Treatment FAQ

what needs to be assessed before starting tb treatment

by Arnoldo Ratke Published 2 years ago Updated 1 year ago
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Medical evaluation, radiography, and the collection of specimens for microbiology are often needed to complete the diagnosis. People with clinical signs and symptoms of TB disease, but negative IGRA or TST, should still be evaluated, especially if TB risk factors are present.

All patients starting MDR-TB treatment should have the following tests.
  1. Acid-fast smear, mycobacterial cultures and DST to rifampicin and isoniazid. ...
  2. Baseline potassium, creatinine, serum glucose and serum glutamic-pyruvic transaminase (SGPT; alanine transaminase (ALT)).

Full Answer

What are the CDC recommendations for tuberculosis (TB) screening?

CDC and the National TB Controllers Association (NTCA) recommend that all U.S. health care personnel be screened for TB upon hire (i.e., pre-placement). Pre-placement screening should include a TB risk assessment, a TB symptom screen, and a TB test.

Do I need a TbTb test?

TB tests are generally not needed for people with a low risk of infection with TB bacteria. Page last reviewed: April 14, 2016 Content source: Division of Tuberculosis Elimination

When should we initiate antiretroviral therapy for tuberculosis (TB)?

Four recent randomised clinical trials [22–25] have shown that initiating ART early during TB treatment in patients with very low CD4+CD4+ T-cell counts improved survival.

What is included in pre-placement screening for tuberculosis (TB)?

Pre-placement screening should include a TB risk assessment, a TB symptom screen, and a TB test.

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What are the guideline for treatment of tuberculosis?

The preferred regimen for treating adults with TB remains a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 months of INH and RIF.

What are the phases of standard treatment in TB that a nurse should be aware of?

treatment regimen consists of an initial 2-month treatment phase followed by a continuation phase of either 4 or 7 months (Table 6.5). The 4-month continuation phase is used for the majority of patients.

What are the activities you would perform in order to monitor a patient's response to treatment?

Monitoring response to treatment is done through regular history taking, physical examination, chest radiograph and laboratory monitoring.

Which of the following tests should be used to monitor the success of treatment for a patient with pulmonary tuberculosis?

New pulmonary TB patients with positive sputum smears at the start of treatment. These patients should be monitored by sputum smear microscopy at the end of the fifth and sixth months. If results at the fifth or sixth month are positive, a sputum specimen should be obtained for culture and DST.

What is the nursing management of a patient with tuberculosis?

First-line agents for the treatment of tuberculosis are isoniazid (INH), rifampin (RIF), ethambutol (EMB), and pyrazinamide. Active TB. For most adults with active TB, the recommended dosing includes the administration of all four drugs daily for 2 months, followed by 4 months of INH and RIF.

What should be done when a health care worker suspects that a patient has TB?

Persons who have or are suspected of having infectious TB disease should be placed in an area away from other patients, preferably in an airborne infection isolation (AII) room.

Why is it important for nurses to assess patients?

The nurse's initial action is patient assessment. 1 Assessment is the foundation of effective nursing care, improved patient outcomes may result from any strategy that enhances patient safety. 2 An appropriate and rapid assessment will improve patient safety.

Which of these rights are checked when with the patient prior to administering the medication?

These five rights refer to the right patient, right medication, right dose, right route, and right time. It is important that these are followed and checked during the process of administering medications to prevent harm and maintain patient safety.

What are the 4 basic rules for medication administration?

The “rights” of medication administration include right patient, right drug, right time, right route, and right dose.

What monitoring is necessary while taking rifampin and isoniazid?

Pharmacodynamic Interactions Isoniazid, when given concomitantly with rifampin, has been reported to increase the hepatotoxicity of both drugs. Patients receiving both rifampin and isoniazid as in RIFAMATE should be monitored closely for hepatotoxicity.

Which of the following tests requires a blood sample for the diagnosis of active pulmonary TB?

Question. Which of the following tests requires a blood sample for the diagnosis of active pulmonary TB? The correct answer is (d). There is no approved blood test for the diagnosis of active pulmonary TB) IGRAs are tested on blood but only give information on latent TB infection, not active disease.

Which of the following diagnostics tests is intended for latent tuberculosis infection?

The main ways to diagnose LTBI are by placing a tuberculin skin test (TST) on the forearm or by getting a TB blood test, in addition to obtaining a chest radiograph (x-ray) if either one of these tests is positive. One-third of the world's population has LTBI. The TB germs are dormant (asleep) in the body.

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2019 TB Screening, Testing, and Treatment of U.S. Health Care Personnel Recommendations

Key Changes in 2019 TB Screening, Testing, and Treatment of U.S. Health Care Personnel Recommendations

CDC and the National Tuberculosis Controllers Association have updated the 2005 CDC recommendations for testing health care personnel given the changing epidemiology of TB in the United States.

How many days apart can you take TB cultures?

After initial conversion, 2 consecutive cultures, taken at least 30 days apart, are found to be positive. Long term. Treatment cure. A patient with bacteriologically confirmed TB at the beginning of treatment who was smear- or culture-negative in the last month of treatment and on at least one previous occasion.

How long does it take to treat tuberculosis with antibiotics?

Antibiotic treatment of tuberculosis has a duration of several months. There is significant variability of the host immune response and the pharmacokineticpharmacodynamic properties of Mycobacterium tuberculosissub-populations at the site of disease. A limitation of sputum-based measures of treatment response may be sub-optimal detection ...

What are the priorities in assessment of response to treatment?

Open in a separate window. Priorities in assessment of response to treatment include both identification and prediction of treatment induced adverse events such as drug side effects and paradoxical reactions, temporary and permanent disability secondary to disease, treatment failure and subsequent relapse.

What is MTB in medical terms?

Mycobacterium tuberculosis (MTB) causes a wide spectrum of disease in different patient groups. Up to one third of the world's population are assumed infected with latent tuberculosis infection (LTBI), a proportion of which will progress to active infection.

What is the goal of a tuberculosis treatment plan?

The goal of the treatment plan is to achieve treatment to cure by the least restrictive means.

What are the barriers to treatment for TB?

Patients with TB often face issues that complicate and can act as barriers to treatment, such as substance abuse, homelessness, unemployment, and lack of healthcare access. Effective case management may obviate the need for legal interventions.

What is LTBI treatment?

The final two bullets address treatment for latent tuberculosis infection (LTBI). Treatment of LTBI is generally initiated after the possibility of TB disease is excluded, and has been proven to greatly reduce the risk that individuals latently infected with TB will progress to TB disease.

What is direct observation therapy?

1) Health care providers may prescribe DOT as a method to monitor the adherence of a patient to his or her prescribed treatment for tuberculosis disease. Health care providers may utilize the Department’s TB Standards of Care as a guideline for appropriate utilization of DOT.

Who is at high risk for developing TB?

Those at high risk for developing TB disease include: People who became infected with TB bacteria in the last 2 years. People who are sick with other diseases that weaken the immune system. People who were not treated correctly for TB in the past.

Who is at increased risk for TB?

Health-care workers who care for patients at increased risk for TB disease. Infants, children and adolescents exposed to adults who are at increased risk for latent tuberculosis infection or TB disease. Many people who have latent TB infection never develop TB disease.

Where is TB common?

People from a country where TB disease is common (most countries in Latin America, the Caribbean, Africa, Asia, Eastern Europe, and Russia) People who live or work in high-risk settings (for example: correctional facilities, long-term care facilities or nursing homes, and homeless shelters)

What are the risks of latent TB?

Many people who have latent TB infection never develop TB disease. But some people who have latent TB infection are more likely to develop TB disease than others. Those at high risk for developing TB disease include: 1 People with HIV infection 2 People who became infected with TB bacteria in the last 2 years 3 Babies and young children 4 People who inject illegal drugs 5 People who are sick with other diseases that weaken the immune system 6 Elderly people 7 People who were not treated correctly for TB in the past

How long after exposure to TB should you be tested?

Health care personnel with a previous negative TB test result should be tested immediately and re-tested 8 to 10 weeks after the last known exposure.

Who developed the recommendations for TB screening?

Experts from the National TB Controllers Association (NTCA), state and local public health departments, academia, occupational health associations, and CDC developed the recommendations after conducting a systematic review of scientific studies on TB screening and testing of health care personnel. Which health care personnel should be screened ...

What is TB screening?

TB screening is a process that includes an individual risk assessment, a symptom evaluation, a TB test (e.g., a TB blood test or a TB skin test), and additional evaluation for TB disease as needed.

What is TB education?

TB education should include information on TB risk factors, the signs and symptoms of TB disease, and TB infection control policies and procedures. TB education materials can be found through CDC, the TB Centers of Excellence for Training, Education, and Medical Consultation, NTCA. , State TB Programs, and the Find TB Resources website.

What are the risk factors for TB?

Risk factors for TB include. exposure to TB disease, time spent in countries where TB is common (e.g., born in or frequent travel to countries with a high rate of TB), and. current or planned immune system suppression (e.g., HIV infection or taking medication that suppresses the immune system).

Do you need annual TB testing?

CDC and NTCA do not recommend annual TB testing for health care personnel unless there is a known exposure or ongoing transmission in a health care setting. All health care personnel should receive TB education annually. TB education should include information on TB risk factors, the signs and symptoms of TB disease, ...

Should health care personnel be screened for TB?

Health care personnel should be screened for TB upon hire (i.e., pre-placement). Annual TB testing is not recommended unless there is a known exposure or ongoing transmission. A positive TB test only tells that a person has been infected with TB bacteria.

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