Treatment FAQ

what minimum treatment for lyme disease

by Maude Altenwerth Published 3 years ago Updated 2 years ago
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For early Lyme disease, a short course of oral antibiotics, such as doxycycline or amoxicillin, cures the majority of cases. In more complicated cases, Lyme disease can usually be successfully treated with three to four weeks of antibiotic therapy.

Medication

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Nutrition

The latest ILADS Lyme Disease Treatment Guidelines were published in 2014 in an open access journal. The guidelines cover three common issues faced by clinicians: management of a known tick bite, antibiotic treatment of patients with erythema migrans rash, and management of patients who remain ill following antibiotic therapy for Lyme disease.

What are the best treatments for Lyme disease?

“People who got Lyme disease and didn’t get treated or got what we call ‘post-treatment Lyme,’ a lot of them are still suffering from it, and we don’t understand why or what to do about it. So that’s the big issue. That’s the bigger issue now ...

What guides the selection of treatment for Lyme disease?

What is the treatment for Lyme disease? The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the second generation cephalosporin, Ceftin.

What is Lyme disease and how is it treated?

What is the initial treatment for Lyme disease?

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What is the initial treatment for Lyme disease?

Oral antibiotics. These are the standard treatment for early-stage Lyme disease. These usually include doxycycline for adults and children older than 8, or amoxicillin or cefuroxime for adults, younger children, and pregnant or breast-feeding women.

How quickly does Lyme disease need to be treated?

Early-stage Lyme disease responds very well to treatment. In most cases, taking an antibiotic for 2 to 4 weeks kills the bacteria and clears up the infection.

Is Stage 1 Lyme disease curable?

If diagnosed in the early stages, Lyme disease can be cured with antibiotics. Without treatment, complications involving the joints, heart, and nervous system can occur. But these symptoms are still treatable and curable.

Can Lyme disease be treated at any stage?

Antibiotics such as those named above can be used in the treatment of late-stage, chronic, and “disseminated” (CDC) Lyme disease. Some doctors, including Lyme-literate doctors, prescribe longer-term antibiotic programs than the typical 2-4 week regimen.

How long should you take doxycycline for Lyme disease?

Early localized Lyme disease — Early localized Lyme disease (the erythema migrans rash, with or without flu-like symptoms) is treated with oral antibiotics, usually doxycycline, amoxicillin, or cefuroxime, taken daily. Doxycycline is given for 10 to 21 days, and amoxicillin and cefuroxime are given for 14 to 21 days.

Is 10 days of doxycycline for Lyme?

The guidelines have consistently recommended a 10-day course of doxycycline for uncomplicated early Lyme disease.

What is uncomplicated early Lyme disease?

The early symptoms of Lyme disease are flu-like, with fever, chills, tiredness, muscle aches, joint pain, and a 'bull's eye' rash.

Can Stage 2 Lyme disease be cured?

Using Antibiotics to Treat Lyme Disease If you already have stage 1 (localized) or stage 2 (early disseminated) Lyme disease with the telltale bull's-eye rash but no other significant symptoms, your doctor will most likely treat you with oral doxycycline, amoxicillin, or cefuroxime for 14 to 21 days.

Can you live a normal life with Lyme disease?

Feb. 1, 2000 (Washington) -- People afflicted with Lyme disease go on to lead normal lives, plagued by the same nettlesome but rarely serious problems that are reported by most people, according to the largest study on the long-term effects of the tick-borne illness.

Can you fully recover from Lyme disease?

Understanding Lyme disease treatment and potential complications can help clear up your concerns. Fortunately, most people with Lyme disease recover fully after completing a course of antibiotics. Lyme disease symptoms may persist for longer, but only in rare cases.

How do you feel when you have Lyme disease?

Erythema migrans is one of the hallmarks of Lyme disease, although not everyone with Lyme disease develops the rash. Some people develop this rash at more than one place on their bodies. Other symptoms. Fever, chills, fatigue, body aches, headache, neck stiffness and swollen lymph nodes can accompany the rash.

What happens if you go untreated for Lyme disease?

What happens if Lyme disease is untreated? Left untreated, Lyme disease can spread to joints and organs, causing significant damage. Arthritis, heart disease, and nervous system problems are common complications of untreated Lyme disease.

What to do if you don't have a lyme disease rash?

Lab tests to identify antibodies to the bacteria can help confirm or rule out the diagnosis. These tests are most reliable ...

What happens after Lyme disease treatment?

After treatment, a small number of people still have some symptoms, such as muscle aches and fatigue. The cause of these continuing symptoms, known as post-treatment Lyme disease syndrome, is unknown, and treating with more antibiotics doesn't help.

What is the test used to detect lyme disease?

Enzyme-linked immunosorbent assay (ELISA) test. The test used most often to detect Lyme disease, ELISA detects antibodies to B. burgdorferi. But because it can sometimes provide false-positive results, it's not used as the sole basis for diagnosis. This test might not be positive during the early stage of Lyme disease, ...

How long does it take for a central nervous system infection to go away?

Intravenous antibiotics. If the disease involves the central nervous system, your doctor might recommend treatment with an intravenous antibiotic for 14 to 28 days. This is effective in eliminating infection, although it may take you some time to recover from your symptoms. Intravenous antibiotics can cause various side effects, ...

How long after an infection can you test for antibodies?

Lab tests to identify antibodies to the bacteria can help confirm or rule out the diagnosis. These tests are most reliable a few weeks after an infection, after your body has had time to develop antibodies. They include: Enzyme-linked immunosorbent assay (ELISA) test.

What to do if you have been bitten by a tick?

Make a list of: Your symptoms, and when they began. All medications, vitamins and other supplements you take, including doses. Questions to ask your doctor.

Can a Western Blot test be positive for lyme disease?

This test might not be positive during the early stage of Lyme disease, but the rash is distinctive enough to make the diagnosis without further testing in people who live in areas infested with ticks that transmit Lyme disease. Western blot test. If the ELISA test is positive, this test is usually done to confirm the diagnosis.

What antibiotics are used for lyme disease?

If your Lyme disease is found soon after you’ve been infected, your doctor will start you on antibiotics: 1 Doxycycline 2 Amoxicillin 3 Cefuroxime

How long do you have to take amoxicillin for lyme disease?

Which drug you’re prescribed will depend on your age. Your doctor will also take into account if you’re pregnant or nursing. You’ll need to take this medicine for 10 to 21 days. The earlier Lyme disease is found, the better. Most people who start treatment in this stage improve quickly.

How long does it take for a lyme disease to go away?

Sometimes, people go through treatment for Lyme disease but their symptoms (feeling run-down and achy) don’t go away. If this lasts over 6 months , it’s known as chronic Lyme disease or “post-treatment Lyme disease syndrome” (PTLDS). Doctors still aren’t sure why some people get PTLDS.

Is Lyme disease better treated with antibiotics?

The earlier Lyme disease is found, the better. Most people who start treatment in this stage improve quickly. If not, your doctor may need to pre scribe another course of antibiotics.

Can IV antibiotics make you sick?

It’s likely this treatment will get rid of the bacteria that’s making you sick. Still, it could take some time for your symptoms to go away. IV antibiotics also come with side effects. These can include diarrhea and a low white blood cell count, which makes it hard for your body to fight off other infections.

Can Lyme disease cause damage to the immune system?

Some believe that getting Lyme disease may cause damage to your tissues or immune system. Others believe it’s because the bacteria that causes Lyme hasn’t completely gone away. There is little evidence that taking more antibiotics at this stage will help. They may actually be harmful.

What is the ILADS treatment plan?

ILADS recommends individualized treatment based on the severity of symptoms, the presence of tick-borne coinfections and patient response to treatment. LDo believes that patients and their doctors should make Lyme disease treatment decisions together. This requires that patients be given sufficient information about the risks and benefits ...

Is there a controversy about Lyme disease?

There is significant controversy in science, medicine, and public policy regarding Lyme disease. Two medical societies hold widely divergent views on the best approach to diagnosing and treating Lyme disease. The conflict makes it difficult for patients to be properly diagnosed and receive treatment.

Is lyme disease hard to catch?

The conflict makes it difficult for patients to be properly diagnosed and receive treatment. One medical society, the Infectious Diseases Society of America (IDSA), regards Lyme disease as “hard to catch and easy to cure” with a short course of antibiotics. IDSA claims that spirochetal infection cannot persist in the body after a short course ...

Can a test determine if a patient has Lyme disease?

There is currently no test that can determine whether a patient has active infection or whether the infection has been eradicated by treatment. The IDSA thinks Lyme disease symptoms after treatment represent a possibly autoimmune, “post-Lyme syndrome” that is not responsive to antibiotics.

Can lyme rash be treated?

They may treat a Lyme rash for a longer period of time than the IDSA recommends, to ensure that the disease does not progress. They are unlikely to withhold treatment pending laboratory test results.

How high is the risk of Lyme disease after treatment?

The rates of Post Treatment Lyme Disease after neurologic involvement may be as high as 20% or even higher. Other risk factors being investigated are genetic predispositions and immunologic variables.

What are the risk factors for lyme disease?

Risk factors for Post Treatment Lyme Disease include: 1 Delay in diagnosis 2 Increased severity of initial illness 3 Presence of neurologic symptoms

How common is PTLD after lyme disease?

The rates of Post Treatment Lyme Disease after neurologic involvement may be as high as 20% or even higher.

What is lyme disease?

Lyme disease encompasses a range of biologic processes and disease manifestations. Patients are often referred to the Lyme Disease Research Center for evaluation of chronic Lyme disease, an umbrella term that encompasses many heterogeneous subsets of illness. Examples of defined Lyme disease subsets include Post Treatment Lyme Disease (PTLD), ...

What antibiotics are used for borrelia?

Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the second generation cep halosporin, Ceftin. The mainstay of treatment is with oral (pill) antibiotics, but intravenous antibiotics are sometimes indicated for more difficult to treat cases of neurologic-Lyme disease, such as meningitis, ...

Can antibiotics help with lyme disease?

The use of antibiotics is critical for treating Lyme disease. Without antibiotic treatment, the Lyme disease causing bacteria can evade the host immune system, disseminate through the blood stream, and persist in the body. Antibiotics go into the bacteria preferentially and either stop the multiplication of the bacteria (doxycycline) ...

Can lyme disease be recurrent?

However, some patients suffer from ongoing or recurrent symptoms related to Lyme disease despite standard of care antibiotic therapy. The persistent symptoms in Lyme disease can have a large negative impact on an individual’s health and quality of life.

What to do if you have a tick borne disease?

Patients with tick-borne diseases should develop a healthy program of light exercise, nutrition and good sleeping habits. While on antibiotics, taking a probiotic containing acidophilus will replenish the “good” bacteria in the GI tract. Organic yogurt and kefir are also good sources of probiotics. Patients may take vitamins, herbs, or even homeopathic remedies to help with cellular repair, boost immune function, help with sleep, detox and inflammation. Always consult with your physician first regarding non-prescription treatments, nutrition and exercise programs.

Can Lyme disease recur?

Recurrence. A patient who seems symptom-free of Lyme should be vigilant for signs of recurrence, as should his or her doctor. Relapses can occur. Many patients can do fine for a period of time after being treated, then start to experience the same or new symptoms.

Can antibiotics cure lyme disease?

Antibiotics are effective in treating many cases of Lyme disease, especially when caught early. However, up to 20 percent of those treated continue to experience lingering symptoms. Some call this post-treatment Lyme disease syndrome, while others call it "chronic" Lyme.

When was the lyme guidelines developed?

Although the IDSA has recently adopted the GRADE assessment protocol, its Lyme guidelines were developed in 2006, before the protocol applied. The IDSA has not updated its Lyme guidelines since that time. The IDSA has denied patient requests to participate in its guideline process for the past 10 years.

How much funding does Lyme disease receive?

However, federal funding of Lyme disease has been meager. For example, while Lyme disease occurs six times more often annually than HIV/AIDS, it receives less than 1% of the funding allotted to HIV/AIDS by the National Institutes of Health. (6)

Why should patients be advised of the benefits and risks associated with both treatment approaches?

Because there are two standards of care in Lyme disease, patients should be advised of the benefits and risks associated with both treatment approaches. They have the right to engage in shared medical decision making with their physicians, a process that recognizes the importance of patient values and preferences in decisions that impact quality ...

How many cases of lyme disease in 2013?

In 2013, the CDC dramatically revised its estimate of the annual incidence of Lyme disease from roughly 30,000 cases per year to over 300,000 cases, a ten-fold increase.

How long have Lyme disease patients been ill?

In a survey of more than 5000 patients with chronic Lyme, half report that they have been ill for more than 10 years. These patients suffer a worse quality of life than those with most other chronic illnesses, including congestive heart failure, diabetes, multiple sclerosis and arthritis. (19)

Is Lyme disease long lasting?

(7, 15-18) Chronic Lyme disease may be long lasting, may significantly impair patient quality of life, and may be costly to patients, employers, healthcare systems, and society.

Is Lyme disease insensitive to HIV?

Unlike tests for HIV/AIDS, which have a sensitivity and specificity of over 99%, Lyme disease tests are highly insensitive and miss more than half of cases. (7) Further uncertainty results from the high rate of treatment failure for all stages of Lyme disease.

How to develop a Lyme disease antibiotic regimen?

The following are four rules to develop a Lyme disease antibiotic regimen. Rule 1. Combine antibiotics to treat all forms of the germ. Borrelia exists in two separate forms. These forms are the spirochete and a cell-wall deficient form that goes by a few names, including “round body,” “L-form,” and “cyst.”.

How to get rid of lyme germs?

To get rid of Lyme germs, all forms must be treated at the same time. Rule 2. Combine antibiotics to treat Lyme living outside and inside of cells. Most physicians think Lyme lives outside of cells in tissues that hold cells and body structures together, or even on nerve coverings.

How often should I rotate my antibiotics?

Generally, I suggest rotating a prescription antibiotic every six months to prevent resistance to that antibiotic. However, I find herbal antibiotics work well for a year or more without changing the herbs. Lyme does not easily develop herbal antibiotic resistance.

Can lyme disease be a persister?

Recent research shows Lyme can form persisters. These are forms of spirochetes and cysts that slow their metabolism way down. In this hibernation state, they can ignore the antibiotics sent to kill them.

Do you need IV antibiotics for lyme disease?

Thus, the majority of people with chronic Lyme do not require IV antibiotics.

Does lyme live inside or outside of cells?

However, Miklossy shows that Lyme lives inside cells and outside of cells. (6) To recover from Lyme, it is necessary to treat Lyme germs living inside cells and outside of cells at the same time. Antibiotics that work inside of cells include the tetracyclines, macrolides, rifamycins, and azoles.

Can a spirochete be treated with doxycycline?

For instance, when the spirochete is exposed to doxycycline, it can convert to a more treatment-resistant cyst form of the germ. At any given time, it is likely that a person with chronic Lyme disease has Borrelia existing in both forms. To get rid of Lyme germs, all forms must be treated at the same time. Rule 2.

What is lyme arthritis?

Lyme arthritis in the knee. Lyme arthritis occurs when Lyme disease bacteria enter joint tissue and cause inflammation. If left untreated, permanent damage to the joint can occur. Lyme arthritis accounts for approximately one out of every four Lyme disease cases reported to CDC. Because of reporting practices, this statistic may overstate ...

How long does it take for lyme arthritis to develop?

Lyme arthritis typically develops within one to a few months after infection .

What are the symptoms of lyme arthritis?

What are the symptoms? The main feature of Lyme arthritis is obvious swelling of one or a few joints. While the knees are affected most often, other large joints such as the shoulder, ankle, elbow, jaw, wrist, and hip can also be involved. The joint may feel warm to the touch or cause pain during movement.

Can you take antibiotics after a first course?

Patients with persistent joint inflammation and pain after the first course of antibiotics may require a second course (see tables below). In some cases, joint swelling and pain can persist or recur after two courses of antibiotics.

Can lyme arthritis be mistaken for septic arthritis?

Lyme arthritis can be mistaken for septic arthritis, especially in children. Whereas septic arthritis may require surgical intervention, Lyme arthritis generally does not. Talk to patients about tick bite prevention.

What antibiotics are used for lyme disease?

Individuals with acute neurological manifestations of Lyme disease should be treated with intravenous ceftriaxone, cefotaxime, penicillin G, or oral doxycycline. Decisions about the choice of antibiotic, including the route of administration, should be based on an individual’s clinical history and preferences.

Who endorses the 2020 guidelines for lyme disease?

(Endorsed, July 2020) The “2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease” was developed by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR) and endorsed by the American Academy of Family Physicians prior to publication.

What is the treatment for erythema migrans?

Individuals with diagnosed erythema migrans should be treated with doxycycline, amoxicillin, or cefuroxime axetil.

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Diagnosis

Treatment

Alternative Medicine

Preparing For Your Appointment

Medically reviewed by
Dr. Rakshith Bharadwaj
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment includes antibiotics.
Medication

Oral antibiotics: Early stages of lyme disease are treated with oral antibiotics.

Doxycycline . Amoxicillin . Tetracycline


Intravenous antibiotics: Prescribed for people whose central nervous system is affected by lyme disease.

Ceftriaxone . Penicillin

Nutrition

Foods to eat:

  • Gluten-free eating
  • Low sugar/ carbohydrate diet
  • Consume food that is rich In vitamins to improve immunity

Foods to avoid:

  • Stop dairy intake
  • Avoid refined sugars

Specialist to consult

Primary care physician
Specializes in the acute and chronic illnesses and provides preventive care and health.

Treatment

  • Many signs and symptoms of Lyme disease are often found in other conditions, so diagnosis can be difficult. What's more, ticks that transmit Lyme disease can also spread other diseases. If you don't have the characteristic Lyme disease rash, your doctor might ask about your medical history, including whether you've been outdoors in the summer where Lyme disease is common, and do …
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Side effects

  • Antibiotics are used to treat Lyme disease. In general, recovery will be quicker and more complete the sooner treatment begins.
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Prognosis

  • Antibiotics are the only proven treatment for Lyme disease. Some people who have unexplained signs and symptoms or chronic disease might believe they have Lyme disease even if it's not been diagnosed. There are a variety of alternative treatments that people with Lyme disease or people who think they have Lyme disease turn to for relief. Unfortunat...
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Roles

  • You're likely to start by seeing your family doctor or a general practitioner who might refer you to a rheumatologist, infectious disease specialist or other specialist. Here's some information to help you get ready for you appointment.
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Research

  • The first-line standard of care treatment for adults with Lyme disease is doxycycline, a tetracycline antibiotic. Other antibiotics that have activity against borrelia include the penicillin-like antibiotic, amoxicillin, and the cephalosporin, Ceftin. In children under the age of 12, amoxicillin is used because of the possible side effects of doxyc...
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Terminology

  • Antibiotics, like all medications, have the potential for side effects. Any antibiotic can cause skin rashes and if an itchy red rash develops while on antibiotics, a patient should see their physician. Sometimes symptoms worsen for the first few days on an antibiotic. This is called a Herxheimer reaction and occurs when the antibiotics start to kill the bacteria. In the first 24 to 48 hours, thes…
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Diagnosis

  • The prognosis after treatment of Lyme disease is generally very good. The majority of people are treated with antibiotics and return to their normal health. The prognosis is best when Lyme disease is diagnosed and treated early and worsens when diagnosis and treatment is delayed. Most patients with early Lyme disease infection recover with antibiotics and return to their norm…
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