Treatment FAQ

what kind of treatment is there for narcolepsy

by Okey Batz Published 3 years ago Updated 2 years ago
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Treatment
  • Stimulants. Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day. ...
  • Selective serotonin reuptake inhibitors (SSRIs) or serotonin and norepinephrine reuptake inhibitors (SNRIs). ...
  • Tricyclic antidepressants. ...
  • Sodium oxybate (Xyrem).
Nov 6, 2020

Medication

Drug Treatments Used for Narcolepsy. Central nervous system stimulants are the main treatments used for excessive daytime sleepiness in narcolepsy, and these stimulants include Amphetamine, Methylphenidate, Modafinil, Dextroamphetamine and Armodafinil.

Nutrition

Dec 09, 2021 · There is no cure for narcolepsy, but medications and lifestyle modifications can help manage symptoms such as excessive daytime sleepiness (EDS). Medications include: Stimulants such as modafinil (Provigil) or armodafinil (Nuvigil) are usually tried first for narcolepsy because they are less addictive than older treatments such as methylphenidate …

What are the natural remedies for narcolepsy?

Solriamfetol : This dual-acting dopamine and norepinephrine reuptake inhibitor is also used to treat narcolepsy. It has proven effective in helping patients stay awake for longer periods of time.

Will there ever be a cure for narcolepsy?

Narcolepsy treatment differs for each person and there is no single medicine that works the same way for everyone. There are however certain medications that have proved very effective in managing narcolepsy. These include modafinil, ADHD medications such as ritalin, sodium oxybate, and some antidepressants.

What is a good diet for someone with narcolepsy?

76 rows · The following list of medications are in some way related to or used in the treatment of this ...

Can you cure narcolepsy?

Substances Antidepressive Agents Central Nervous System Stimulants Neuropeptides Methylphenidate Sodium Oxybate

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What triggers narcolepsy attacks?

It is often triggered by sudden, strong emotions such as laughter, fear, anger, stress, or excitement. The symptoms of cataplexy may appear weeks or even years after the onset of EDS. Some people may only have one or two attacks in a lifetime, while others may experience many attacks a day.

What are the 5 signs of narcolepsy?

There are 5 main symptoms of narcolepsy, referred to by the acronym CHESS (Cataplexy, Hallucinations, Excessive daytime sleepiness, Sleep paralysis, Sleep disruption). While all patients with narcolepsy experience excessive daytime sleepiness, they may not experience all 5 symptoms.

What do doctors prescribe for narcolepsy?

If necessary, a GP or specialist may prescribe a type of medicine known as a stimulant, such as modafinil, dexamphetamine, methylphenidate or pitolisant. These medicines stimulate your central nervous system, which can help keep you awake during the day. They're usually taken as tablets every morning.

How can I get rid of narcolepsy naturally?

Natural Ways to Stay Awake With Narcolepsy
  1. 1 / 11. Stay Awake Naturally. The world narcolepsy was coined in 1880s to mean “seized by somnolence,” or sleepiness. ...
  2. 2 / 11. Schedule Naps. ...
  3. 3 / 11. Rest Best at Night. ...
  4. 4 / 11. Eat Your Way Awake. ...
  5. 5 / 11. Watch Your Carbs. ...
  6. 6 / 11. Move. ...
  7. 7 / 11. Seek Sunshine. ...
  8. 8 / 11. Keep Cool.
Jul 20, 2021

Do people with narcolepsy feel tired all the time?

The most obvious narcolepsy symptom is excessive daytime sleepiness (EDS) which refers to an inability to stay alert during normal daytime hours. The individual feels persistently sleepy, no matter how much sleep he or she gets at night.Dec 3, 2020

How do you test for narcolepsy?

To do the MSLT, a sleep specialist will monitor you while you take five naps, two hours apart. If it takes you less than eight minutes to fall asleep on average, and you fall into REM sleep in at least two of the naps, you are considered to have narcolepsy.Jul 22, 2020

How do you stop narcolepsy?

Management of narcolepsy consists of medications and lifestyle changes. The goal of medications is to reduce daytime sleepiness and improve alertness. A number of medications with varying mechanisms of action in the brain are now available for the treatment of excessive daytime sleepiness (EDS).Mar 16, 2020

What foods help narcolepsy?

Research is limited, but some people with narcolepsy say their symptoms improve when they follow a ketogenic (or keto) diet, which is a restrictive, low-carbohydrate, high-fat, moderate-protein diet. “There's some clinical data from small studies of low-carbohydrate, ketogenic diet in people with narcolepsy,” Li says.Jul 2, 2021

Does Adderall help narcolepsy?

Adderall is a prescription medication that doctors commonly prescribe to treat attention deficit hyperactivity disorder, or ADHD. Adderall can also help treat narcolepsy, which is a sleep disorder.

Does B12 help with narcolepsy?

Conclusion. Decreased serum vitamin B12 levels are independently associated with the development of narcolepsy, which illustrates the complex relationship between vitamin B12 and narcolepsy. Future studies should explore whether vitamin B12 supplementation can improve the symptoms of patients.

Can CBD help narcolepsy?

Results: Hourly analysis of sleep data showed that CBD blocked the sleepiness during the lights-off period across 7h post-injection in lesioned rats. Conclusion: Taking together, these preliminary findings suggest that CBD might prevent sleepiness in narcolepsy.

Does magnesium help narcolepsy?

Certain nutrients, such as magnesium and vitamin B, may help control narcolepsy symptoms. A diet rich in nutrients and low in carbohydrates will optimize the body's performance throughout the day.Oct 5, 2020

How to treat narcolepsy?

Treatment for narcolepsy can be broken down into two categories: 1 Behavioral approaches employ changes in lifestyle and daily habits to manage symptoms and reduce the likelihood of other physical and emotional challenges that often affect people with narcolepsy. 2 Medications can be prescribed to address symptoms. The use of medications is known as pharmacotherapy.

Is narcolepsy curable?

Narcolepsy is not curable. It is considered to be a lifelong condition. For the majority of patients, symptoms stay relatively stable over time. A significant number see symptom improvement 4 or, in some rare cases, remission 5 as they age.

What are the risks of narcolepsy?

Its central symptom is excessive daytime sleepiness (EDS), which may involve falling asleep involuntarily, even while eating or driving. People with narcolepsy face safety risks including a three- to four-fold increase 2 in their chances of being in an automobile accident. Narcolepsy symptoms can also cause significant impairment in school, work, ...

What are the behavioral elements of narcolepsy?

Behavioral elements of narcolepsy treatment involve lifestyle strategies that are meant to combat excessive daytime sleepiness, prevent accidental injuries, and fortify physical, mental, and emotional health. People with narcolepsy can adapt these non-medical treatment methods to fit their individual situation.

Is narcolepsy a life threatening condition?

People with narcolepsy are at a higher risk of accidents while driving, operating heavy machinery, or engaging in other safety-critical activities. Accidents can be life-threatening, making the prevention of involuntary sleep an important element of narcolepsy care.

Can narcolepsy cause accidents?

Well-timed naps may enable safer driving for short distances. The risk of accidents can depend on the severity t of excessive daytime sleepiness as well as the presence of other symptoms, like cataplexy.

Can narcolepsy cause fragmented sleep?

Treating fragmented sleep in people with narcolepsy can be challenging. Typical prescription sleep medications, such as benzodiazepines or “Z drugs,” have a strong sedative effect that can persist into the morning, worsening daytime EDS.

What is the best treatment for narcolepsy?

Central nervous system stimulants are the main treatments used for excessive daytime sleepiness in narcolepsy, and these stimulants include Amphetamine, Methylphenidate, Modafinil, Dextroamphetamine and Armodafinil.

Can narcolepsy be cured?

Although people suffering from narcolepsy can’t be cured, they can be helped. Treatment for this disorder is tailored to each individual and is based on the person’s symptoms and therapeutic response. It could well take months, or even longer, to achieve effective control of symptoms.

Is narcolepsy a neurological disorder?

Narcolepsy can be described as a neurological condition involving a person’s reduced ability to manage the sleep-wake cycle. Although people suffering from narcolepsy can’t be ...

Can narcolepsy run in families?

The symptoms of narcolepsy are generally first noticed in young adults or teenagers, but narcolepsy can occur in both women and men at any age. In fact, there’s strong evidence that narcolepsy could run in families, because approximately 10% of people diagnosed with narcolepsy with cataplexy already have a close family member with this neurological disorder. As mentioned previously, narcolepsy can be confused with depression, and it’s true that there is a link between these two disorders. The co-occurrence of depression in narcolepsy patients has produced mixed results, though, with different studies producing numbers anywhere between 6% and 50%.

How to help narcolepsy?

There are several things you can do at home to help improve the symptoms of narcolepsy and include the following: Maintain a regular sleep schedule. Many people have an improvement in their symptoms if they maintain a regular sleep schedule, usually seven to eight hours of sleep per night. Schedule naps during the day.

What are the best medications for narcolepsy?

Drugs that act as stimulants and/or reduce the other symptoms of narcolepsy are standard treatments for the condition. They include: Armodafinil ( Nuvigil ): This drug is similar to Provigil. It is also used to reduce excessive daytime sleepiness. Headache and nausea are the most common side effects. Methylphenidate Hcl ( Daytrana, Ritalin ...

What is Xywav used for?

Sodium oxybate ( Xyrem, Xywav): This drug is used to treat a small subset of people with narcolepsy who have excessive daytime sleepiness and cataplexy that does not respond to the other medications. It is the only drug approved by the FDA for cataplexy.

Is Wakix a controlled substance?

It has a history of abuse as a recreational drug; therefore, the FDA has classified it as a controlled substance. Pitolisant ( Wakix ): This new drug is also used to treat those who experience excessive daytime sleep.

Does Pitolisant work on histamine receptors?

It acts on the histamine receptors and mimics histamine. Pitolisant uses the histamine receptors to prompt your brain to stay awake. Solriamfetol ( Sunosi ): This dual-acting dopamine and norepinephrinere uptake inhibitor is also used to treat narcolepsy.

What are the side effects of Prozac?

Side effects of Prozac and the other SSRIs also include stomach upset and sexual dysfunction.

Medications to Treat Narcolepsy

There are several medications that can combat and help reduce the effects of narcolepsy. Typically, these medications fall into two categories: stimulants that promote alertness and wakefulness; and anti-depressants and sedatives that help ensure a more regulated sleep, treat cataplexy, and can decrease overall anxiety.

Lifestyle changes

Because narcolepsy is a chronic lifelong condition with a wide range of different symptoms and causes, it is important to seek medical help to determine the right combination of medication and lifestyle adjustments. Besides medications, there are several ways people can adapt their lifestyle to reduce the effects of narcolepsy.

Resources

https://www.mayoclinic.org/diseases-conditions/narcolepsy/diagnosis-treatment/drc-20375503#:~:text=Selective%20serotonin%20reuptake%20inhibitors%20 (SSRIs,hypnagogic%20hallucinations%20and%20sleep%20paralysis.

Drugs used to treat Narcolepsy

The following list of medications are in some way related to, or used in the treatment of this condition.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

What is narcolepsy type 1?

Narcolepsy type 1 and narcolepsy type 2 are central disorders of hypersomnolence. Narcolepsy type 1 is characterized by excessive daytime sleepiness and cataplexy and is associated with hypocretin-1 deficiency.

What is the difference between narcolepsy type 1 and narcolepsy type 2?

Narcolepsy type 1 and narcolepsy type 2 are central disorders of hypersomnolence. Narcolepsy type 1 is characterized by excessive daytime sleepiness and cataplexy and is associated with hypocretin-1 deficiency. On the other hand, in narcolepsy type 2, cerebrospinal fluid hypocretin-1 levels are normal and cataplexy absent. Despite major advances in our understanding of narcolepsy mechanisms, its current management is only symptomatic. Treatment options may vary from a single drug that targets several symptoms, or multiple medications that each treats a specific symptom. In recent years, narcolepsy treatment has changed with the widespread use of modafinil/armodafinil for daytime sleepiness, antidepressants (selective serotonin and dual serotonin and noradrenalin reuptake inhibitors) for cataplexy, and sodium oxybate for both symptoms. Other psychostimulants can also be used, such as methylphenidate, pitolisant and rarely amphetamines, as third-line therapy. Importantly, clinically relevant subjective and objective measures of daytime sleepiness are required to monitor the treatment efficacy and to provide guidance on whether the treatment goals are met. Associated symptoms and comorbid conditions, such as hypnagogic/hypnopompic hallucinations, sleep paralysis, disturbed nighttime sleep, unpleasant dreams, REM- and non REM-related parasomnias, depressive symptoms, overweight/obesity, and obstructive sleep apnea, should also be taken into account and managed, if required. In the near future, the efficacy of new wake-promoting drugs, anticataplectic agents, hypocretin replacement therapy and immunotherapy at the early stages of the disease should also be evaluated.

To treat EDS and sleep attacks

People with narcolepsy experience EDS every day. Medication doesn’t provide complete relief from EDS, but it can help prevent serious accidents.

Treating disrupted nighttime sleep

Many people with narcolepsy experience disrupted nighttime sleep (DNS), where they wake often during the night. There aren’t many FDA-approved medications to treat disrupted nighttime sleep symptoms.

Treatment for cataplexy, hallucinations, and sleep paralysis

For people with type 1 narcolepsy, medication can help treat cataplexy, hallucinations, and sleep paralysis.

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