Treatment FAQ

what is treatment for bv if clindamycin and flagyl cannot be used

by Helena McGlynn Published 3 years ago Updated 3 years ago

Medication

The ASOA said it remained legal in the UK to:

  • Give antibiotics to farm animals routinely, rather than just when they are sick
  • Give preventative group treatments to farm animals
  • Give antibiotics to farm animals to compensate for inadequate hygiene
  • Import animal foods produced with antibiotic growth promoters.

Self-care

Vibramycin (doxycycline) is safe for people age 65 or older and those who have kidney problems. Flagyl (metronidazole) is good at killing a variety of bacteria. Unlike many other antibiotics, Flagyl (metronidazole) is less likely to make bacteria resistant to it.

Nutrition

Clindamycin isn’t practical because you’re not treating the cause of bacterial vaginosis; you’re only treating the frustrating symptoms you’re experiencing. Another problem you’ll find with using clindamycin to treat bacterial vaginosis is that some women are allergic to this antibiotic.

What antibiotic is similar to Flagyl?

Yes. Continue taking all your usual medications including aspirin, and anti-inflammatory arthritis medication if they are part of your daily medication regimen. Is it OK to get the vaccine if I’m on an antibiotic or do I need to wait?

Is Flagyl stronger than doxycycline?

Does clindamycin really treat bacterial vaginosis?

Can I take clindamycin with Flagyl?

What else can treat BV Besides metronidazole?

To treat bacterial vaginosis, your doctor may prescribe one of the following medications:Metronidazole (Flagyl, Metrogel-Vaginal, others). This medicine may be taken as a pill by mouth (orally). ... Clindamycin (Cleocin, Clindesse, others). ... Tinidazole (Tindamax). ... Secnidazole (Solosec).

How do I get rid of BV when antibiotics don't work?

Probiotics, live bacteria found in some foods and supplements, might help restore balance to your vaginal bacteria. Studies show that eating yogurt or probiotic supplements may treat bacterial vaginosis, and is quite safe. Another promising remedy is boric acid, a white powder with antifungal and antiviral properties.

What happens if Flagyl doesn't work for BV?

Alternative antibiotic treatments Tinidazole tablets may be offered if you know you are intolerant of metronidazole. Tinidazole is a similar antibiotic and you need to take 2 g once a day for two days, or 1 g once a day for five days.

Is Flagyl the only treatment for BV?

There are three equally effective treatments for bacterial vaginosis: the most common is metronidazole (Flagyl), which comes either as a pill or a cream.

How do you get rid of stubborn vaginosis?

Current treatment guidelines include seven days of either oral antibiotic tablets or the insertion of a vaginal antibiotic cream for seven nights. These antibiotics have 80% to 90% cure rates one month after treatment. But more than half of treated women get BV back again within six months.

How do you treat chronic BV?

Abstract. Bacterial vaginosis (BV) is a common but treatable condition, with a number of effective available treatments, including oral and intravaginal metronidazole and clindamycin and oral tinidazole. However, as many as 50% of women with BV experience recurrence within 1 year of treatment for incident disease.

What can BV be mistaken for?

Often, BV can be mistaken for other conditions, such as yeast infections or sexually transmitted diseases, such as chlamydia. Often, BV (or STDs) do not have any symptoms at all, so it's imperative always to make a yearly gynecological appointment.

What if BV keeps coming back?

It's common for BV to come back, usually within 3 months. You'll need to take treatment for longer (up to 6 months) if you keep getting BV (you get it more than twice in 6 months). A GP or sexual health clinic will recommend how long you need to treat it.

Does chronic BV ever go away?

Some women suffer from chronic (recurring) bacterial vaginosis. Medicine can clear up the infection, but it returns again after a few weeks. Some women report that bacterial vaginosis returns after their period each month. Or it can return after they have sex.

Why is metronidazole not working for BV?

Second, the bacteria that either cause BV or cause the anaerobic overgrowth may have become relatively more resistant to metronidazole (the most common treating agent) or to clindamycin (the other common treating agent).

What is the best antibiotic for a bacterial infection?

Bacterial infections are treated with antibiotics such as amoxicillin, erythromycin and ciprofloxacin. There are many different types of antibiotic, with different ways of working; the choice depends on the type of infection you have.

What is better for BV clindamycin or metronidazole?

There was no statistically significant difference between the two results. Side effects for both regimens were comparable. We conclude that 2% clindamycin vaginal cream offers similar efficacy and safety to standard oral metronidazole therapy for bacterial vaginosis.

Who needs treatment for bacterial vaginosis?

Not everyone with BV needs antibiotics. In some mild or low risk cases, the vagina will restore the balance of good bacteria and the condition will resolve on its own.

What bacterial vaginosis treatment is best for me?

The best treatment for BV varies by individual and depends on a few different things :

How long does it take for BV to clear?

These treatments have been around a while, and are proven to work: 80% of women treated for BV using one of these methods are clear of the infection one month after treatment .

Can metronidazole cause nausea?

Pills usually give more side effects than creams, and for metronidazole pills, these might include a headache, nausea, or stomach pain. Both metronidazole pills and creams can give you a metallic taste in your mouth.

Can you use clindamycin vaginally?

If you are using clindamycin vaginally, you’ll need to be careful using latex condoms for protection. Clindamycin cream can weaken condoms to the point that they break.

Can BV be treated with antibiotics?

Luckily, BV is easily treated with simple antibiotics. In some women, the infection comes back, and they have to take antibiotics for longer to get rid of the infection completely.

Do women get better with BV?

Many women don’ t know that they have BV. That’s ok. One-third of women get better with no treatment at all.

Can bacterial vaginosis be cured?

BV will sometimes go away without treatment. But if you have symptoms of BV you should be checked and treated. It is important that you take all of the medicine prescribed to you, even if your symptoms go away. A health care provider can treat BV with antibiotics, but BV may recur even after treatment.

Resources for Clinicians

Vaginitis Self-Study Module external icon – An online learning experience that helps users learn how to manage vaginitis. Free CME/CNE available. (November 1, 2017)

What antibiotics are used for bacterial vaginosis?

Bacterial vaginosis can cause symptoms such as discharge with an unpleasant smell. The antibiotics clindamycin and metronidazole are both effective treatments for bacterial vaginosis. There has not yet been enough research on the possible benefits of lactic acid bacteria treatments. Bacterial vaginosis is quite common and caused by changes in the vaginal flora that allow the rapid growth of specific types of bacteria (usually gardnerella). The infection can cause a thin, grayish-white discharge with an unpleasant smell, but it often goes undetected. If it does produce symptoms, antibiotics can be used as an effective treatment, even during pregnancy. Treatment can help lower the slightly increased risk of miscarriage due to the infection, too.

What is the best treatment for bacterial vaginosis?

Bacterial vaginosis can cause symptoms such as discharge with an unpleasant smell. The antibioticsclindamycin and metronidazole are both effective treatments for bacterial vaginosis. There has not yet been enough research on the possible benefits of lactic acid bacteriatreatments.

How long does it take for clindamycin to show symptoms?

88% of the study participants who used clindamycin had no symptoms one to two weeks after treatment.

Can antibiotics cause premature births?

Antibiotics had no influence on the risk of premature births or on stopping a woman’s water from breaking sooner. About 2% of the women stopped treatment due to side effects. There is no evidencethat antibioticsused to treat bacterial vaginosis have any long-term side effects or are harmful for the child.

Is metronidazole good for vaginosis?

Clindamycin and metronidazole are very effective against vaginosis symptoms. Studies on clindamycin cream treatments have shown the following:

Does clindamycin cause nausea?

Other side effects may also occur. Metronidazole tablets leave behind a metallic taste in about 10% of women. Less commonly, they cause nausea and vomiting. Clindamycin is very well tolerated when used as a cream, and aside from yeast infections it has no other known side effects.

Can lactic acid be used in combination with antibiotics?

There are hardly any studies testing them on their own – they are usually used in combination with antibiotics. But no evidencehas been found that vaginosis clears up any better with this combination. Little is known about possible side effects.

What is the best medicine for bacterial vaginosis?

To treat bacterial vaginosis, your doctor may prescribe one of the following medications: Metronidazole (Flagyl, Metrogel-Vaginal, others). This medicine may be taken as a pill by mouth (orally). Metronidazole is also available as a topical gel that you insert into your vagina.

How long does Clindamycin last in vagina?

This medicine is available as a cream that you insert into your vagina. Clindamycin cream may weaken latex condoms during treatment and for at least three days after you stop using the cream. Tinidazole (Tindamax). This medication is taken orally.

How long does it take for bacterial vaginosis to recur?

It's common for bacterial vaginosis to recur within three to 12 months, despite treatment. Researchers are exploring treatments for recurrent bacterial vaginosis. If your symptoms recur soon after treatment, talk with your doctor about treatments. One option may be extended-use metronidazole therapy.

How to check for anaerobic bacteria?

Take a sample of vaginal secretions. This may be done to check for an overgrowth of anaerobic bacteria in your vaginal flora. Your doctor may examine the vaginal secretions under a microscope, looking for "clue cells," vaginal cells covered with bacteria that are a sign of bacterial vaginosis.

How to boost the number of good bacteria in your vagina?

A self-help approach is lactobacillus colonization therapy — which attempts to boost the number of good bacteria in your vagina and re-establish a balanced vaginal environment — possibly accomplished by eating certain types of yogurt or other foods containing lactobacilli.

How to make the best use of your time with your doctor?

To make the best use of your time with your doctor and prevent you from forgetting an important question: Make a list of any symptoms you're experiencing. Include all of your symptoms, even if you don't think they're related. Make a list of any medications, vitamins, herbs or other supplements you take.

How to diagnose bacterial vaginosis?

Open pop-up dialog box. Close. Pelvic examination. Pelvic examination. In a pelvic exam, your physician inserts two gloved fingers inside your vagina. While simultaneously pressing down on your abdomen, he or she can examine your uterus, ovaries and other organs. To diagnose bacterial vaginosis, your doctor may: ...

Why don't antibiotics work on BV?

Why antibiotics don’t work on BV. You may have a diagnosis of bacterial vaginosis with or without symptoms. Either way the problem is the same: Gardnerella vaginalis and friends have made a sticky bacterial biofilm on your vaginal cells and they are not giving up their position.

How long does it take for BV to come back?

The usual treatment for BV is antibiotics, however more often than not, the BV ‘comes back’ after a month or two. The three-month success rate of antibiotics is about half. This is because in many cases,the BV never really goes away; the bacterial biofilm home-grown by Gardnerella vaginalis and friends is still in there, ...

What is the book Killing BV?

We’ve written a book, Killing BV, detailing how to get rid of the bacterial biofilm caused by G. vaginalis.

What is the name of the drug that has not worked?

Clindamycin (Cleocin, oral or vaginal, Clindesse, vaginal) Tinidazole (Tindamax, oral) If you have tried antibiotics, and they haven’t worked, you may be treating the wrong bacteria or have antibiotic-resistant bacteria. Posted on March 27, 2014. September 4, 2020.

Do antibiotics help with vaginal biofilm?

This biofilm causes your vagina to become too alkaline, kills off the Lactobacillus, and causes unpleasant symptoms. Antibiotics merely put a few bullet holes in the biofilm, but they are not effective in dissolving it. Antibiotics work for some women, and should be tried, because if they do work they are an excellent option and save much heartache.

How to treat BV?

Another alternative for treating BV is to induce a vaginal flora shift from a BV- to a Lactobacillus-dominated flora by promoting the growth of lactobacilli. The principle behind prebiotics is to provide nutriments that stimulate the growth of lactobacilli. Oligosaccharides can selectively promote the growth of lactobacilli that in turn generate lactic acid to lower the vaginal pH and secrete antibacterial substances that inhibit the adhesion and replication of the anaerobic bacteria.74Some authors have proposed the topical application of a gel containing sucrose, a disaccharide of glucose and fructose, to treat BV. A Phase III clinical trial was conducted including women with symptomatic BV who were randomly assigned into three groups for vaginal application of sucrose (5 g), metronidazole (0.75%), and placebo gels, twice daily for 5 consecutive days.75The therapeutic cure rates (according to FDA guidelines) evaluated 21–35 days after the start of treatment were 61%, 67%, and 7%, respectively, for sucrose, metronidazole, and placebo gel groups. These results suggest that sucrose has a therapeutic cure rate similar to the metronidazole gel. Interestingly, at the intermediate visit (7–10 days after the start of treatment), the therapeutic cure rate was statistically higher for the sucrose group (83%) than for the metronidazole group (71.3%) and the placebo group (0.9%). The evaluation of lactobacilli based on the Nugent score at the 5–7 days visit showed significantly higher levels of lactobacilli in the sucrose gel group compared with the metronidazole group. These results suggest that by promoting the growth of lactobacilli, sucrose gel restores normal vaginal flora more rapidly than does metronidazole. However, while the rate of adverse events after sucrose gel was found to be similar with that found in the other groups, treatment with sucrose would be expected also to promote the development of candidosis.

What is the treatment for BV?

This lincosamide antibiotic, a subclass of the larger family of macrolide antibiotics, has various treatment preparations including vaginal (ovule and cream) and oral. Clindamycin vs placebo .

What is BV in a vagina?

BV is characterized by the alkalinization of vaginal fluid (vaginal pH > 4.5) prompting some authors to propose correcting the vaginal pH in order to treat BV. The results have been discordant. In two randomized double-blind clinical trials, vaginal acidification alone (5 mL acetic acid gel intravaginally twice daily for 7 days or 5 g acid-buffering formulation gel intravaginally once daily for 5 days) was an ineffective therapy for BV compared with placebo or metronidazole.59,60However, in another randomized study, the combination of oral metronidazole 500 mg twice daily and 5 g lactic acid vaginal gel at bedtime for 7 days was found to be better than metronidazole alone at promoting lactobacilli colonization and reducing malodorous vaginal discharge.61Moreover, not only was the lactic acid well tolerated but it also reduced recurrence of symptomatic BV.61

What is BV in women?

Bacterial vaginosis (BV) is a common cause of malodorous vaginal discharge in women of reproductive age.1Women’s awareness of BV is low and often they self-medicate with antifungals before presenting very late when symptoms have become intolerable.

What is metronidazole used for?

Metronidazole is a nitroimidazole antimicrobial agent used to manage protozoal infections such as trichomoniasis and anaerobic infections.18 Since the early 1980s, metronidazole has been used widely in the treatment of BV with good clinical results.

What essential oils are good for BV?

Essential oils from medicinal plants have strong antiseptic properties. Two recent studies have suggested the use of thymol and eugenol for BV therapy.69,70Thymol is a natural monoterpene phenol found in oil of thyme, with an in vitro activity on G. vaginalisbiofilms; and eugenol is a phenylpropene extracted in particular from clove oil. Both were applied via vaginal douche once daily for 7 days and resulted in a similar significant reduction in symptoms as that obtained with vaginal metronidazole.70Beyond reducing symptoms, the effect of thymol on vaginal flora should however be analyzed.

Is secnidazole a placebo?

No study has evaluated the efficacy of secnidazole compared with placebo. The efficacy of secnidazole was however compared with the mainstay of BV therapy, metronidazole. A randomized, double-blind, noninferiority study was conducted according to FDA guidance to compare the efficacy of a single 2 g oral dose of secnidazole compared with a 7-day course of 500 mg metronidazole administered orally twice daily.37The secnidazole regimen was shown to be at least as effective as the multiple-dose metronidazole regimen. The therapeutic cure at the 28-day follow up was 60% in the secnidazole group and 59% in the metronidazole group. Secnidazole was well tolerated and adverse events were similar in both groups (38% in the metronidazole group and 39% in the secnidazole group). Although headaches were rarely reported, they were more frequent in the secnidazole group (9% vs 4%).

How long does metronidazole last?

Recommended treatment for recurrent BV consists of an extended course of metronidazole treatment (500 mg twice daily for 10-14 days); if ineffective, metronidazole vaginal gel 0.75% for 10 days, followed by two times per week for 3-6 months, is an alternate treatment regimen.

Is BV a common disease?

Bacterial vaginosis (BV) is a common but treatable condition, with a number of effective available treatments, including oral and intravaginal metronidazole and clindamycin and oral tinidazole. However, as many as 50% of women with BV experience recurrence within 1 year of treatment for incident dis …

Is BV a treatable condition?

Bacterial vaginosis (BV) is a common but treatable condition, with a number of effective available treatments, including oral and intravaginal metronidazole and clindamycin and oral tinidazole. However, as many as 50% of women with BV experience recurrence within 1 year of treatment for incident disease. Some reasons for recurrence include the ...

How long does it take for BV to go away after taking clindamycin?

Studies on the efficacy of clindamycin have shown that 88% of the study participants did not experience any BV symptoms 1–2 weeks after using the cream.

How often can you take Flagyl?

People can take metronidazole tablets (Flagyl) twice per day for 7 days or take a single tablet as a one-time dose.

What is BV medication?

Bacterial vaginosis (BV) medication: Options, side effects, and more. Bacterial vaginosis (BV) is a vaginal infection. Antibiotics may help treat the condition and reduce symptoms. Some antibiotics can cause side effects, and there are some Food and Drug Administration (FDA) warnings on certain BV drugs.

How long does clindamycin stay in your vagina?

Clindamycin comes as a single, pre-filled applicator containing 5 grams (g) of the medication that a person inserts into their vagina every night for 5 days. The CDC. Trusted Source. suggests that individuals avoid using latex and rubber condoms during treatment and for 5 days after use.

What are the symptoms of yeast infection?

Symptoms of a yeast infection include lumpy, white vaginal discharge or vaginal itching and redness.

What are the symptoms of BV?

Trusted Source. : pain, itching, or burning sensation in the vagina. painful urination. white or gray vaginal discharge. discharge with a fish-like odor.

How to diagnose BV?

To diagnose BV, a doctor may perform a pelvic exam and take a sample of the vaginal discharge.

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