Treatment FAQ

what is the typical treatment for first stage colon cancer

by Vince Schmitt Published 2 years ago Updated 1 year ago
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The most common treatment for early stage colon cancer is surgery. Some patients with early stage disease may also receive chemotherapy after surgery. For patients with localized colon cancer, the five-year survival rate is 90 percent.

Medication

Stage I cancers have a survival rate of 80-95 percent. Stage II tumors have survival rates ranging from 55 to 80 percent. A stage III colon cancer has about a 40 percent chance of cure and a patient with a stage IV tumor has only a 10 percent chance of a cure.

Procedures

How long will a person with stage 4 colon cancer live?

  • Diagnosis. A doctor may recommend multiple tests to accurately diagnose colon cancer. ...
  • Decisions. Anyone who receives a stage 4 colon cancer diagnosis will have to make some decisions about the way forward, particularly regarding treatment options.
  • Treatment options. ...
  • Outlook. ...
  • Summary. ...

Therapy

Treating stage II colon cancer Many stage II colon cancers have grown through the wall of the colon, and maybe into nearby tissue, but they have not spread to the lymph nodes. Surgery to remove the section of the colon containing the cancer (partial colectomy) along with nearby lymph nodes may be the only treatment needed.

Nutrition

Your specific colon resection strategy will depend on many factors, including the following:

  • The location of the tumor
  • The presence of other cancers or polyps
  • The stage of the cancer
  • The risk of developing colon cancer in the future
  • Your preferences

See more

What is the survival rate of Stage 1 colon cancer?

What is the life expectancy of someone with colon cancer?

Is there a cure for Stage II colon cancer?

What is the best treatment for colon cancer?

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How is Stage 1 colon cancer treated?

Treatment for stage 1 large bowel (colon) cancer Surgery is the main treatment. People with very early colon cancer (stage 1) do not usually need chemotherapy. But this might change after surgery. After your operation, a specialist doctor (pathologist) looks closely at your cancer.

Can colon cancer be cured at stage 1?

Stage 1 colon cancer is an early-stage cancer that can be cured without chemotherapy or radiation. Removal of the cancerous tissue with surgery or during colonoscopy is the primary treatment. Many people do well after their stage 1 colon cancer is treated.

What is the first line treatment for colorectal cancer?

In many cases, bevacizumab is recommended as a component of the first-line treatment of metastatic colorectal cancer, along with FOLFIRI, FOLFOX, FOLFOXIRI, or XELOX/CAPOX.

How long does it take stage 1 colon cancer to progress?

Colon cancer, or cancer that begins in the lower part of the digestive tract, usually forms from a collection of benign (noncancerous) cells called an adenomatous polyp. Most of these polyps will not become malignant (cancerous), but some can slowly turn into cancer over the course of about 10-15 years.

Does Stage 1 cancer need chemo?

Chemotherapy is usually not part of the treatment regimen for earlier stages of cancer. Stage 1 is highly treatable, however, it does require treatment, typically surgery and often radiation, or a combination of the two.

How long does it take colon cancer to progress from Stage 1 to Stage 4?

The clock ticks at a rate of about one mutation every two years. Markowitz and his team discovered that it takes about 17 years for a small colon polyp—also called an adenoma, the first, non-deadly stage of colon cancer—to develop into a more dangerous advanced carcinoma.

How soon after colon surgery Do you start chemotherapy?

The start of chemotherapy treatment usually requires a delay of about 4 weeks after surgical resection in patients with primary colorectal cancer and synchronous distant metastasis.

Is there a chemo pill for colon cancer?

Chemotherapy drugs used to treat colorectal cancer Capecitabine (Xeloda), a pill that is changed into 5-FU once it gets to the tumor. Irinotecan (Camptosar) Oxaliplatin (Eloxatin) Trifluridine and tipiracil (Lonsurf), a combination drug in pill form.

Do you have to have a colostomy bag after colon surgery?

Once you have recovered from surgery, you will need to empty the colostomy pouch, also called a colostomy bag. You will probably do this several times a day. You will not be able to control when stool and gas move into the pouch. It is best to empty it when the bag is less than half full.

What are symptoms of stage 1 colon cancer?

A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool. Rectal bleeding or blood in your stool. Persistent abdominal discomfort, such as cramps, gas or pain. A feeling that your bowel doesn't empty completely.

How long after colon cancer diagnosis is surgery?

The median time from diagnosis to surgery was 25 days. Approximately 18.1% of the sample had surgery within 10 days of diagnosis, and 10.4% had surgery within 41 to 50 days of colon cancer diagnosis.

What is the average life expectancy with colon cancer?

5-year relative survival rates for colon cancerSEER stage5-year relative survival rateLocalized91%Regional72%Distant14%All SEER stages combined64%Mar 1, 2022

Treating Stage 0 Colon Cancer

Since stage 0 colon cancers have not grown beyond the inner lining of the colon, surgery to take out the cancer is often the only treatment needed....

Treating Stage I Colon Cancer

Stage I colon cancers have grown deeper into the layers of the colon wall, but they have not spread outside the colon wall itself or into the nearb...

Treating Stage II Colon Cancer

Many stage II colon cancers have grown through the wall of the colon, and maybe into nearby tissue, but they have not spread to the lymph nodes.Sur...

Treating Stage III Colon Cancer

Stage III colon cancers have spread to nearby lymph nodes, but they have not yet spread to other parts of the body.Surgery to remove the section of...

Treating Stage IV Colon Cancer

Stage IV colon cancers have spread from the colon to distant organs and tissues. Colon cancer most often spreads to the liver, but it can also spre...

Treating Recurrent Colon Cancer

Recurrent cancer means that the cancer has come back after treatment. The recurrence may be local (near the area of the initial tumor), or it may b...

What is the earliest stage of colon cancer?

At its earliest stage (stage 0), colon cancer is limited to the inner lining of your colon. As colon cancer progresses, it can grow through your colon and extend to nearby structures. The most advanced stage of colon cancer (stage IV) indicates cancer has spread to other areas of the body, such as the liver or lungs.

How to tell what stage of colon cancer you have?

The stages of colon cancer are indicated by Roman numerals that range from 0 to IV, with the lowest stages indicating cancer that is limited to the lining of the inside of the colon.

How does chemotherapy help with colon cancer?

Chemotherapy uses drugs to destroy cancer cells. Chemotherapy for colon cancer is usually given after surgery if the cancer is larger or has spread to the lymph nodes. In this way, chemotherapy may kill any cancer cells that remain in the body and help reduce the risk of cancer recurrence.

What is the procedure to check for colon cancer?

Colonoscopy. During a colonoscopy , the doctor inserts a colonoscope into your rectum to check for abnormalities in your entire colon. If your signs and symptoms indicate that you could have colon cancer, your doctor may recommend one or more tests and procedures, including:

What tests are needed for colon cancer?

Staging helps determine what treatments are most appropriate for you. Staging tests may include imaging procedures such as abdominal, pelvic and chest CT scans.

What is the treatment for cancer?

Immunotherapy. Immunotherapy is a drug treatment that uses your immune system to fight cancer. Your body's disease-fighting immune system may not attack your cancer because the cancer cells produce proteins that blind the immune system cells from recognizing the cancer cells.

Is a colon ostomy permanent?

Sometimes the ostomy is only temporary, allowing your colon or rectum time to heal after surgery. In some cases, however, the colostomy may be permanent. Lymph node removal. Nearby lymph nodes are usually also removed during colon cancer surgery and tested for cancer.

What is the best treatment for colon cancer?

If you have colon cancer, your treatment team will include medical oncologists, surgeons and radiation oncologists. These specialists will work together to develop the best treatment plan for your condition. Colon cancer treatment will depend on how early the cancer is caught. Sometimes, your doctor can remove polyps during a colonoscopy ...

What is the treatment for gastrointestinal cancer?

Other treatment options for late stage gastrointestinal cancers may include cytoreductive (debulking) surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).

What happens after colon cancer surgery?

Following colon cancer surgery, vigilant monitoring is a critical part of follow-up care. There is a risk of recurrence, especially if the cancer involved the lymph nodes. After your surgery, your doctor will see you at the following times:

What is the treatment for cancer after surgery?

This is called neoadjuvant therapy. In more advanced cancers, you may need a course of chemotherapy following your surgery. This type of chemotherapy is generally administered on an outpatient basis. Chemoradiation (chemotherapy combined with radiation therapy) may also be used after surgery.

What percentage of colon cancer patients have localized disease?

Some patients with early stage disease may also receive chemotherapy after surgery. For patients with localized colon cancer, the five-year survival rate is 90 percent.

How does chemotherapy work?

Chemotherapy drugs travel through the bloodstream to destroy tumor cells that may have broken away from original tumor and could begin to grow again elsewhere in the body. They may be administered orally or intravenously. Chemotherapy can be used at various stages of colon cancer treatment.

Where does colon cancer spread?

When colon cancer metastasizes (spreads), it usually appears in the liver. It may also spread to the lungs, brain, peritoneum (the lining of the abdominal cavity) and/or distant lymph nodes. For patients with this type of late stage disease, the five-year survival rate is 14 percent.

What is colon cancer?

Key Points. Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon. Health history affects the risk of developing colon cancer. Signs of colon cancer include blood in the stool or a change in bowel habits. Tests that examine the colon and rectum are used to diagnose colon cancer.

What are the risk factors for colon cancer?

Risk factors for colorectal cancer include the following: Having a family history of colon or rectal cancer in a first-degree relative (parent, sibling, or child). Having a personal history of cancer of the colon, rectum, or ovary.

Where does colon cancer spread?

Cancer has spread from the mucosa of the colon wall to the submucosa or to the muscle layer. In stage I colon cancer, cancer has formed in the mucosa (innermost layer) of the colon wall and has spread to the submucosa (layer of tissue next to the mucosa) or to the muscle layer of the colon wall.

How do you know if you have colon cancer?

Signs of colon cancer include blood in the stool or a change in bowel habits. These and other signs and symptoms may be caused by colon cancer or by other conditions. Check with your doctor if you have any of the following: A change in bowel habits. Blood (either bright red or very dark) in the stool.

Where are abnormal cells found in the colon?

Abnormal cells are shown in the mucosa of the colon wall. In stage 0, abnormal cells are found in the mucosa (innermost layer) of the colon wall. These abnormal cells may become cancer and spread into nearby normal tissue. Stage 0 is also called carcinoma in situ.

How does chemo work?

When chemotherapy is taken by mouth or injected into a vein or muscle , the drugs enter the bloodstream and can reach cancer cells throughout the body ( systemic chemotherapy ). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas ( regional chemotherapy ).

Is a colostomy permanent?

If the doctor needs to remove the entire lower colon, however, the colostomy may be permanent. Enlarge. Colon cancer surgery with colostomy. Part of the colon containing the cancer and nearby healthy tissue is removed, a stoma is created, and a colostomy bag is attached to the stoma.

What is the procedure to remove a tumor from the colon?

They may call this procedure a polypectomy. If you have larger tumors, your surgeon may need to take out the diseased part of the colon and reattach the healthy tissue so that your bowels still work .

Where does stage 2 colorectal cancer go?

Stage II Colorectal Cancer Treatment. Stage II colorectal cancers are larger and go through the muscular wall of the bowel. They may have spread to places nearby like the bladder, uterus, or prostate gland.

What is the best medicine for cancer?

Bevacizumab ( Avastin ), cetuximab ( Erbitux ), or panitumumab ( Vectibix ). These drugs work on your immune system. Your doctor may call them monoclonal antibodies. Ziv-Aflibercept ( Zaltrap) if your cancer has gotten worse or doesn’t respond to other treatment.

What is stage IV cancer?

Stage IV colorectal cancers have spread to far-off parts of the body, often the liver or lungs. Your doctor may say the cancer has “metastasized” or call it "metastatic” cancer. The tumor can be any size and may or may not include your lymph nodes. Treatment may include: Chemotherapy.

Where does stage 1 cancer spread?

The cancer hasn’t spread to the outer wall of the bowel or outside it . At this stage, most people will have surgery to remove the cancer and a small amount of tissue around it.

Can you get radiation before or after surgery?

You may get radiation and chemotherapy before or after surgery. Stage III Colorectal Cancer Treatment. Stage III colorectal cancers have spread to one or more lymph nodes. Your doctor may talk about stage lIl A, B, or C tumors. Here’s what that means: Stage lIlA.

Can colorectal cancer come back?

Doctors call colorectal cancer “recurrent” if it comes back (recurs) after treatment. It can happen in the same area or in a different part of your body. Recurrence is most likely in people who had more advanced colorectal cancer the first time. Treatment may involve: Surgery to take out the cancer.

What is the treatment for stage 1 colon cancer?

STAGE I COLON CANCER. For stage I colon cancer, surgery is also often the recommended treatment. It will typically be either: Colectomy (resection) — removal of all or part of your colon through one incision.

What are the treatments for metastatic disease?

Often, chemotherapy and radiation are combined with surgery to shrink tumors.

What is stage IV CRC?

Treatment for stage IV or recurrent colorectal cancer is complex, and generally requires consultation with medical, surgical and radiological doctors.

What is the National Comprehensive Cancer Network?

The National Comprehensive Cancer Network is a “not-for-profit alliance of centers that develops practice guidelines to help in making informed treatment decisions.” NCCN Guidelines for Patients® are easy-to-understand resources and may help you with treatment decision making.

Is colorectal cancer treated by stage?

Colorectal cancer treatment by stage can be straightforward in the early stages, but it can become incredibly complicated once the cancer progresses. Our Guide in the Fight includes more detailed colorectal cancer treatment by stage for stage III, IV and recurrent cancers.

Is colon cancer a stage 2 node negative?

Treatment of node-negative stage II colon cancer is controversial. While surgery to remove the tumor in the colon is universally accepted as an initial treatment, the value of chemotherapy after that surgery (adjuvant chemotherapy) to keep cancer from recurring (coming back) is hard for patients and doctors to judge.

Can stage 3 rectal cancer be treated with chemotherapy?

For stage III rectal cancer patients who are medically fit and can tolerate combined methods of therapy, treatment can consist of chemoradiation (chemotherapy and radiation) before surgery (adjuvant therapy), abdominal surgery, and/or adjuvant chemotherapy after surgery. Patients who cannot tolerate chemoradiation at first, ...

What is the best treatment for colon cancer?

Surgery is often the only treatment needed for stage 0 colon cancer. Stage 1. Surgery alone is recommended for stage 1 colon cancer.

What is the stage 1 colon cancer?

Stage 1 colon cancer indicates the cancer has grown into the inner layer of the colon, called the mucosa, to the next layer of the colon, called the submucosa. It hasn’t spread to the lymph nodes.

What tests are needed to determine if a colon cancer is spread?

Diagnostic tests performed may include imaging of the abdomen, liver, and chest with CT scans, X-rays, or MRI scans.

What to do if you test positive for colorectal cancer?

If after taking a FIT test or a sigmoidoscopy you test positive for colorectal cancer, your healthcare provider will suggest a colonoscopy to confirm your diagnosis. A colonoscopy is a screening test where the doctor uses a long, narrow tube with a small camera attached to view the inside of your colon.

How do you know if you have colon cancer?

At later stages, symptoms tend to vary based on tumor size and location in your large intestine. These symptoms can include: change in bowel habits. blood in stool or rectal bleeding.

What is the most advanced stage of colon cancer?

4A stage. This stage indicates that cancer has spread to one distant site, such as the liver or lungs. 4B stage. This most advanced stage of colon cancer indicates cancer has spread to two or more distant sites, such as the lungs and liver.

What is cancer stage classification?

Cancer stage classifications. Within each category, the disease is classified even further and assigned a number or a letter to indicate the extent of the disease. These assignments are based on the structure of the colon, as well as how far the cancer has grown through the layers of the colon wall.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves surgery and chemotherapy.
Medication

Targeted drugs: The specific sites which can be cancerous are targeted and the drugs are administered.

Bevacizumab . Ramucirumab


Chemotherapy: To destroy the cancer cells and relieve symptoms.

5-Fluorouracil . Capecitabine . Irinotecan . Oxaliplatin


Immunotherapy: To treat the type of cancers which might respond to the antibodies.

Nivolumab . Pembrolizumab

Procedures

Colonoscopy: To visualize and remove/biopsy the polyps.

Laparoscopy: To remove the polyps which can not be removed using colonoscopy.

Endoscopic mucosal resection: Procedure where a small section of the colon lining that has cancerous tissue is removed.

Bowel resection with colostomy: Involves creating another way for elimination of connecting healthy tissue to a pouch attached to skin and removing the cancerous tissue.

Lymphadenectomy: Nearby lymph nodes are removed and tested for malignancy so as to ensure the death of all the cancerous cells.

Partial colectomy: Removal of the part of colon with cancer and then reconnecting it with healthy tissue.

Therapy

Radiation therapy:Therapy involves the usage of high energy beams like X-rays to destroy cancer cells.

Nutrition

Foods to eat:

  • low-fat high-fiber diet – fruits and vegetables
  • Antioxidants – kidney beans, goji berries, wild berries

Foods to avoid:

  • high fat fast foods
  • Red meat

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Gastroenterologist
Specializes in the digestive system and its disorders.
Colon and rectal surgeon
Specializes in dealing with disorders of the rectum, anus, and colon.

Preparing For Your Appointment

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