Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it. Sometimes, radiation is given as well. Systemic therapy (chemotherapy) may be used if a malignant phyllodes tumor has spread outside of the breast, though this not common.
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What are the treatment options for a phyllodes tumor?
Surgery remains the mainstay of the treatment in patients with malignant phyllodes tumor of the breast (MPTB); however, the extent of surgery (breast conserving surgery [BCS] versus mastectomy) and the role of adjuvant radiotherapy have been controversial. We report a single institution's experience …
Can a phyllodes tumor return after breast cancer surgery?
Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it. Sometimes, radiation is given as well. Systemic therapy (chemotherapy) may be used if a malignant phyllodes tumor has spread outside of the breast, though this not common. Your oncology team will recommend a treatment plan based on what …
What is the prognosis of phyllodes cancer?
Jul 20, 2021 · Complete excision, with accurate histologic examination and continued follow-up care, is the best way to treat phyllodes tumors. A general surgery specialist should be consulted. In most cases,...
What are the symptoms of a phyllodes tumor?
Eighty-one female patients with phyllodes tumors of the breast, surgically treated from 1974 to 1983, were studied. Their age ranged from 9 to 88 years. According to histology, the series was divided into three groups, of 28 (34.5%) benign tumors, 32 (39.5%) border-line tumors, and 21 (25.9%) malign …
How fast does a phyllodes tumor grow?
Phyllodes Tumor Symptoms Phyllodes tumors can grow to 3 centimeters wide -- a little more than an inch -- in just a few weeks or months. They often grow quickly, even if they're benign. You may notice them bulging through your skin. Sometimes, they can stretch your skin or cause an ulcer on your breast.Aug 29, 2020
Is a phyllodes tumor considered cancer?
A phyllodes tumor is a rare tumor of the breast. Phyllodes tumors grow in the connective tissue of your breast, called the stroma. The American Cancer Society says that most phyllodes tumors aren't cancerous, so they don't often spread outside your breast. However, they can grow quickly.
What are the chances of phyllodes tumor recurrence?
A mean systemic recurrence rate of 13.6% (range, 3.2%-25%) for phyllodes tumors has been reported in the international literature. In our study, the recurrence rate was 15%; all of these recurrences were in patients with resection margins around the primary tumor that were less than 1 cm.
Can phyllodes Tumours grow again?
Sometimes, phyllodes tumours can come back in the same area of breast tissue (known as a local recurrence). This risk is higher with malignant tumours. If this does happen, your surgeon may advise that you have further surgery. This may involve another wide local excision to remove the tumour.
Can phyllodes spread?
Malignant (cancerous) tumors account for about 1 in 4 phyllodes tumors. These tend to grow the fastest and are the most likely to spread or to come back after treatment.Jan 25, 2022
Where do phyllodes tumors spread?
Treatment of phyllodes tumors of the breast It's rare for phyllodes tumors to spread to the lymph nodes, so lymph node surgery usually isn't needed. If the phyllodes tumor is cancerous, radiation therapy may be given to the area where the tumor was after surgery.Jan 20, 2022
How often do benign phyllodes tumors recur?
Earlier published studies have shown that 28%-44% of local recurrence in benign phyllodes tumour present with higher histologic grades than the primary tumour, likewise borderline phyllodes can show recurrence ranges from 14%-25% and transformation to malignant phyllodes are seen in 12%-54% of recurrences [5,7].Mar 29, 2020
What is a borderline phyllodes tumor?
A phyllodes tumour is a growth of cells that forms a hard lump in the breast. Phyllodes tumours can be: benign (not cancer) malignant (cancer) borderline (somewhere between benign and malignant)
Can benign phyllodes turn malignant?
Very rarely, benign phyllodes tumours can develop into a borderline or malignant phyllodes tumour. If your tumour does come back, you'll need to have further surgery.
How big is a 3 cm tumor?
Tumor sizes are often measured in centimeters (cm) or inches. Common food items that can be used to show tumor size in cm include: a pea (1 cm), a peanut (2 cm), a grape (3 cm), a walnut (4 cm), a lime (5 cm or 2 inches), an egg (6 cm), a peach (7 cm), and a grapefruit (10 cm or 4 inches).Aug 29, 2008
Are phyllodes tumors movable?
Phyllodes tumor is the most commonly occurring nonepithelial neoplasm of the breast, though it represents only about 1% of tumors in the breast. It has a smooth, sharply demarcated texture and typically is freely movable.Jul 20, 2021
Is a lumpectomy major surgery?
In a lumpectomy, only the affected portion of the breast is removed, without removing the surrounding healthy breast tissue. Lumpectomy is also called breast-conserving surgery. Lumpectomy is a commonly performed surgery but still major surgery with risks and potential complications.Oct 20, 2020
What is a benign breast tumor called?
They may look very much like common benign breast tumors called fibroadenomas. Often, the pathologist needs to look at the whole tumor under the microscope to make a diagnosis. This is why surgery to remove a phyllodes tumor is recommended, even if it is thought to be benign.
What is the best treatment for phyllodes cancer?
Only if the cancer is known to have spread to other parts of the body will systemic therapy be recommended. Local therapy is aimed at preventing the tumor from coming back in the breast. Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it.
Why are phyllodes tumors called leaf tumors?
Their unusual name comes from the Greek word for “leaf”, because they have a leaf-like appearance under the microscope. Some inherited genetic disorders are known to increase the risk of developing a phyllodes tumor, but in most cases, the cause is unknown.
Where do phyllodes start?
Unlike breast cancer which begins in the milk ducts, malignant phyllodes tumors begin in the connective tissue that surrounds and supports the ducts and lobules of the breast. Phyllodes tumors contain different kinds of cells, but the cancerous part is a sarcoma, or cancer of connective tissue. These tumor cells are very different ...
Can phyllodes be treated?
Treatment of malignant phyllodes tumors is also somewhat different than that of more common kinds of breast cancer. Phyllodes tumors that are only in the breast, whether benign or malignant, are most often treated with local therapy alone. Only if the cancer is known to have spread to other parts of the body will systemic therapy be recommended .
Can phyllodes grow quickly?
Unlike other kinds of benign breast lesions, benign phyllodes tumors can grow very quickly and become very large. Malignant phyllodes tumors are a form of breast cancer; however, they are different from more common kinds of breast cancer.
Do sarcomas spread through the lymphatic system?
This is because when sarcomas spread, they typically do not travel through the lymphatic system. Even when sarcomas are very large tumors, lymph nodes are usually negative for cancer, and axillary lymph node dissection (removal of the lymph nodes under the arm) is often not necessary.
What are the complications of phyllodes tumor surgery?
Complications. Surgical treatment of phyllodes tumors, like most surgical procedures of the breast, may have the following complications: Infection . Seroma formation.
Can axillary lymph node dissection be performed?
Axillary lymph node dissection should be performed only for clinically suspicious nodes. However, virtually all of these nodes are reactive and do not contain malignant cells. [ 31] There is no proven role for adjuvant chemotherapy or radiation therapy in the treatment of phyllodes tumors.
How is it diagnosed?
To confirm that you have a phyllodes tumor you may need the following diagnostic tests after a physical examination by the breast specialist.
How is it treated?
Surgical excision forms the mainstay of treatment for phyllodes.Since phyllodes tumours are notorious to recur, it is advisable to get the surgery done when they are small enough to be removed without needing to remove excess breast tissue. Differ..
Lumpectomy
Simple Lumpectomy: Removes the tumor, along with at least 1 centimeter (0.4 inches) of tissue around it. Removing this extra tissue helps to reduce the risk of the tumor from returning. This procedure safely removes the lump without disfiguring the breast. No extra surgery is required for shaping the breast .
Oncoplastic Surgery
Large volume excision with oncoplastic surgery to reshape the breast : For a larger tumor, the surgeon needs to remove a larger part of the breast tissue alongwith the lump. This leads to cosmetic disfigurement for which specialist oncoplastic surgical techniques are used to fill the gap created in the breast.
Total Mastectomy
Total mastectomy with or without reconstruction: In this , the whole breast is removed. Our breast clinic specialists will also assist you for a reconstruction surgery if you desire to have one. Total mastectomy is generally needed for malignant phylloides, especially for the larger tumour or those that recur.
Chemotherapy
Conventional chemotherapy and radiotherapy have little if any role to play in treatment.
What is a phyllodes tumor?
What Are Phyllodes Tumors? Phyllodes tumors are a rare type of breast growth. Less than 1% of all breast tumors are this type. Most are not cancer, called benign. But about 25% of these tumors are cancerous (or malignant). Some are borderline, a mix of benign and cancerous. Phyllodes tumors start in your breast’s stromal, or connective, tissue.
How long after breast surgery can you get a phyllodes tumor?
Follow-up treatment. Because phyllodes tumors can return, you need careful follow-up after your surgery. Within 4 to 6 months of your surgery, see your doctor for a breast exam, mammogram, and ultrasound.
What is the procedure to remove a lump?
Excisional biopsy or lump removal. Most people need this procedure to get a diagnosis. Your surgeon will remove the whole lump and examine the tissue. This biopsy can show if your tumor is benign, borderline cancer, or malignant. Phyllodes Tumor Treatment. All phyllodes tumors, even benign ones, require surgery.
How to tell if a lump is a phyllodes tumor?
Tests can tell whether a lump is a phyllodes tumor. Mammogram. Your doctor may suspect a phyllodes tumor because of something they see on a regular mammogram or ultrasound. It will show detailed images of the lump. A phyllodes tumor has a clearly defined round or oval shape.
How long after phyllodes surgery do you need a CT scan?
If your phyllodes tumor was malignant, you may need regular CT scans of your chest and abdomen for 5 years after your surgery. Your outlook is excellent if you had a benign tumor removed with surgery. Treatment often cures malignant phyllodes tumors, but they’re more likely to grow back.
What is the best way to diagnose a lump?
Needle biopsy. Your doctor may do a core needle biopsy of your lump to confirm your diagnosis. They’ll take a small sample of tissue with a hollow needle and use a microscope to check for signs of cancer. Excisional biopsy or lump removal. Most people need this procedure to get a diagnosis.
Where do phyllodes start?
Some are borderline, a mix of benign and cancerous. Phyllodes tumors start in your breast’s stromal, or connective, tissue. Phyllodes means “leaflike.”. That’s because as they grow, the tumors have the shape of a leaf. All phyllodes tumors may grow.
What is a phyllodes tumor?
Phyllodes tumors of the breast are rare tumors that start in the connective (stromal) tissue of the breast. [1] [2] They get their name from the leaf-like pattern in which they grow (phyllodes means leaf-like in Greek). [2] [3] They are most common in women in their 30s and 40s, although women of any age can be affected. These tumors, which are usually painless, tend to grow quickly, but rarely spread outside of the breast. [1] [2] Most phyllodes tumors are benign. About 1 in 10 are cancerous. [1] The underlying cause of these tumors in unknown. [3] Surgery is the main treatment. Because the tumors can reoccur if they are not removed with enough surrounding tissue, the tumor and at least 1 cm of tissue should be removed. Cancerous phyllodes tumors are often treated with mastectomy. Close follow-up with frequent breast examinations are recommended after surgery. [1] [2]
What is the survival rate of a malignant phyllodes tumor?
[3] . The five year survival rate for malignant phyllodes tumors has been reported to be 60 to 80 percent. [4]
What is an orphanet?
Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Phyllodes tumor of the breast. Click on the link to view a sample search on this topic.
What is monarch tool?
Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.
What is support and advocacy?
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services.
Why is research important?
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Is a phyllodes tumor benign?
These tumors, which are usually painless, tend to grow quickly, but rarely spread outside of the breast. [1] [2] Most phyllodes tumors are benign. About 1 in 10 are cancerous. [1] . The underlying cause of these tumors in unknown. [3] . Surgery is the main treatment.
What is borderline tumor?
overgrown connective tissue cells with an unusual appearance. Borderline tumors have features of the benign and malignant forms. Malignant tumors — particularly those with lots of connective tissue overgrowth — may spread and grow quickly, possibly spreading beyond the breast.
What is a phyllodes tumor?
Phyllodes tumors are a rare type of breast tumor. The pattern of their cells resembles leaves, and the name “phyllodes” comes from the Greek word meaning “leaf-like.”. Phyllodes tumors can grow quickly, but they do not always spread beyond the breast. Authors of a 2013 review note that 35–64%. Trusted Source.
How old do phyllodes tumors develop?
Phyllodes tumors can form at any age, but they tend to affect women aged 35–55 years. Trusted Source. . Those that develop in younger women are more likely to be benign. Very rarely, phyllodes tumors develop in males. Trusted Source. , usually in those with a condition called gynecomastia.
What is a biopsy of a tumor?
A biopsy involves taking tissue samples for testing. These tests provide confirmation of the type of tumor. A doctor may recommend a core needle biopsy or an excisional biopsy. A core needle biopsy involves the doctor taking a sample through the skin, using a hollow needle.
Why is my breast blue?
It can become visible as it pushes against the skin of the breast, and it may expand the veins under the skin, causing that area of the breast to appear blue. The tumor may cause an ulcer to form on the skin of the breast, but this is rare. An ulcer can form whether the tumor is benign, borderline, or malignant. .
When do fibroadenomas appear?
Second, phyllodes tumors tend to develop about 10 years later, when people are in their 40s. Fibroadenomas tend to appear when people are in their 20 and 30s. These distinctions can help a doctor make an accurate diagnosis.
Can a phyllodes tumor recur?
If a malignant phyllodes tumor recurs, there is a limited risk of this type of tumor developing beyond the breast. Only 5% of all phyllodes tumors recur elsewhere the body, according to Breastcancer.org.
What is a malignant phyllodes tumor?
Malignant phyllodes tumors are different from the more common types of breast cancer. They are less likely to respond to some of the treatments commonly used for breast cancer, such as hormone therapy or the chemotherapy drugs normally used for breast cancer. Phyllodes tumors that have spread to other parts of the body are often treated more like ...
What is a fill odes tumor?
Phyllodes Tumors of the Breast. Phyllodes tumors (FILL-odes or full-OH-deez) can also be spelled phylloides tumors (full-OY-deez). These are rare breast tumors that start in the connective (stromal) tissue of the breast. Phyllodes tumors are most common in women in their 40s, but women of any age can have them.
How to tell if a tumor is fibroadenomas?
The tumors are usually felt as a painless breast lump, but some may hurt. They tend to grow quickly and stretch the skin. Sometimes they are seen first on an imaging test (like an ultrasound or mammogram ), in which case they’re often hard to tell apart from fibroadenomas . The diagnosis can often be made with a core needle biopsy, but sometimes the entire tumor needs to be removed (during an excisional biopsy) to know for sure that it’s a phyllodes tumor, and whether it's malignant or not.
Can a woman have a phyllodes tumor?
Phyllodes tumors are most common in women in their 40s, but women of any age can have them. Women with Li-Fraumeni syndrome (a rare, inherited genetic condition) have an increased risk for phyllodes tumors. Most phyllodes tumors are benign (not cancer), but about 1 out of 4 of these tumors are malignant (cancer).
Does phyllodes cancer come back?
Having a benign phyllodes tumor does not affect your breast cancer risk, but you may be watched more closely and get regular imaging tests, because these tumors can come back after surgery.
How long does it take for a phyllodes tumor to come back?
Phyllodes tumors aren’t usually cancerous, but they can sometimes return after treatment. Usually, these tumors come back within a year or two after you have surgery. Cancerous tumors may come back sooner.
What is a phyllodes tumor?
A phyllodes tumor is a rare tumor of the breast. Phyllodes tumors grow in the connective tissue of the breast, called the stroma. This includes the tissue and ligaments that surround the ducts, blood vessels, and lymph vessels in the breast. The name “phyllodes” comes from the Greek word for “leaflike.”. The name describes the pattern the cells of ...
What is the difference between a fibroadenoma and a phyllodes tumor?
They aren’t cancerous. The main difference between the two conditions is that phyllodes tumors grow faster and start later in life.
Is a phyllodes tumor cancerous?
of all breast tumors are of this type. About 90 percent of phyllodes tumors aren’t cancerous, so they don’t often spread outside the breast. However, they can grow quickly. Some phyllodes tumors are between benign and cancerous. These types are considered “borderline.”.
Can a phyllodes tumor grow?
Even though a phyllodes tumor is benign, it can grow and cause pain and other problems. Your doctor will recommend that you have surgery to remove it. The surgeon will remove not only the tumor, but also some of the healthy tissue around it.
Can a phyllodes tumor grow under skin?
The tumor may grow quickly enough that you can eventually see it under your skin. Even though most phyllodes tumors aren’t cancerous, they can grow and cause pain. If the tumor breaks through your skin, you might see an open sore on your breast.