Treatment FAQ

what is the treatment or cure for syphilis

by Dolores Davis Published 2 years ago Updated 2 years ago
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A single injection of long-acting Benzathine penicillin G can cure the early stages of syphilis. This includes primary, secondary, or early latent syphilis. CDC recommends three doses of long-acting Benzathine penicillin G at weekly intervals for late latent syphilis or latent syphilis of unknown duration.

Medication

The recommended treatment for neurosyphilis, ocular syphilis, or otosyphilis is Aqueous crystalline penicillin G 18-24 million units per day, administered as 3-4 million units intravenously every 4 hours or continuous infusion, for 10-14 days. Treatment will prevent disease progression, but it might not repair damage already done.

Self-care

Syphilis can usually be treated with a short course of antibiotics. It's important to get it treated because syphilis won't normally go away on its own and it can cause serious problems if left untreated. Antibiotics for syphilis. A short course of antibiotics can usually cure syphilis.

Nutrition

Some basic questions to ask your doctor include:

  • What's the medical name of the infection I have?
  • How is it transmitted?
  • Will it keep me from having children?
  • If I get pregnant, could I give it to my baby?
  • Is it possible to catch this again?
  • Could I have caught this from someone I had sex with only once?
  • Could I give this to someone by having sex with that person just once?
  • How long have I had it?

More items...

How long does it take to treat and cure syphilis?

Those without a history of treatment for syphilis should be offered treatment. Unless a medical history or results of a physical examination indicate a recent infection, previously untreated persons should be treated for syphilis of unknown duration or late latent syphilis.

Will syphilis ever go away?

What drug is used to treat syphilis?

When to treat syphilis?

Can syphilis be cured?

Does penicillin kill syphilis?

Is there a cure for syphilis?

Can you take penicillin for syphilis?

See more

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How is syphilis treated and cured?

When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin desensitization.

Can syphilis be cured or just treated?

Yes, syphilis is curable with the right antibiotics from your healthcare provider. However, treatment might not undo any damage the infection can cause.

What is the fastest treatment for syphilis?

Treating and curing syphilis Primary and secondary syphilis are easy to treat with a penicillin injection. Penicillin is one of the most widely used antibiotics and is usually effective in treating syphilis. People who are allergic to penicillin will likely be treated with a different antibiotic, such as: doxycycline.

What does syphilis look like on a man?

A person with primary syphilis generally has a sore or sores at the original site of infection. These sores usually occur on or around the genitals, around the anus or in the rectum, or in or around the mouth. These sores are usually (but not always) firm, round, and painless.

Are syphilis sores itchy?

usually does not cause itching. may appear as rough, red, or reddish-brown spots on the palm of the hands and bottoms of the feet. However, rashes with a different appearance may occur on other parts of the body. Sometimes they resemble rashes caused by other diseases.

What is one of the first signs of syphilis?

The first sign of syphilis is a small sore, called a chancre (SHANG-kur). The sore appears at the spot where the bacteria entered your body. While most people infected with syphilis develop only one chancre, some people develop several of them. The chancre usually develops about three weeks after exposure.

How long does it take for syphilis to go away?

As the bacteria spread through your blood, you may get a fever, a sore throat, and swollen glands. You may also feel generally weak and tired. Like primary syphilis, the signs and symptoms of secondary syphilis go away on their own without treatment in 2 to 6 weeks.

What causes syphilis in a woman?

Syphilis is a sexually transmitted disease (STD) caused by an infection with bacteria known as Treponema pallidum. Like other STDs, syphilis can be spread by any type of sexual contact. Syphilis can also be spread from an infected mother to the fetus during pregnancy or to the baby at the time of birth.

Syphilis - STI Treatment Guidelines

12/20/2021: Dear Colleague Letter Regarding Possible False RPR Reactivity with Syphilis Test pdf icon FDA issued an alert that false reactivity, or “false-positive,” Rapid Plasma Reagin (RPR; non-treponemal) test results, when using the Bio-Rad Laboratories BioPlex 2200 Syphilis Total & RPR kit, can occur in some people who received a COVID-19 vaccine.

How Long Does It Take To Treat and Cure Syphilis?

Syphilis is a common infection in people, especially adults, around the world. Consequently, it is important for you to know what it is, and what causes it. This will help you know how to treat it, and how long it should take.

Syphilis - Diagnosis and treatment - Mayo Clinic

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Sexually Transmitted Infections Treatment Guidelines, 2021

Morbidity and Mortality Weekly Report Recommendations and Reports / Vol. 70 / No. 4 July 23, 2021 Sexually Transmitted Infections Treatment Guidelines, 2021

What test can confirm syphilis?

Blood. Blood tests can confirm the presence of antibodies that the body produces to fight infection. The antibodies to the syphilis-causing bacteria remain in your body for years, so the test can be used to determine a current or past infection. Cerebrospinal fluid.

How to prevent HIV infection?

Avoid sexual contact with new partners until the treatment is completed and blood tests indicate the infection has been cured. Notify your sex partners so that they can be tested and get treatment if necessary. Be tested for HIV infection.

Can you cure syphilis with penicillin?

When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin desensitization.

How long do side effects of syphilis last?

Joint or muscle pain. All of the above, plus nausea and chills. If you do have side effects, they typically only last about 24 hours. Once you’ve completed your treatment, the antibiotics will kill the bacteria that cause syphilis and prevent any additional problems from occurring because of that particular case.

Can syphilis cause blindness?

Syphilis can cause blindness or paralysis. It increases your chances of getting and spreading HIV, the virus that causes AIDS. Over time, it can damage your organs and even lead to death. And, of course, if you’re not treated, you’ll likely spread the STD to your sexual partner.

Can you get syphilis again?

And, they’ll advise you to be tested for HIV and avoid all sexual contact until blood tests confirm you’re cured. And remember that getting treatment doesn’t mean you can’t get syphilis again or spread it at a later time.

Nontreponemal Tests and Traditional Algorithm

False-positive nontreponemal test results can be associated with multiple medical conditions and factors unrelated to syphilis, including other infections (e.g., HIV), autoimmune conditions, vaccinations, injecting drug use, pregnancy, and older age ( 566, 569 ).

Treponemal Tests and Reverse Sequence Algorithm

The majority of patients who have reactive treponemal tests will have reactive tests for the remainder of their lives, regardless of adequate treatment or disease activity. However, 15%–25% of patients treated during the primary stage revert to being serologically nonreactive after 2–3 years ( 570 ).

Cerebrospinal Fluid Evaluation

Further testing with CSF evaluation is warranted for persons with clinical signs of neurosyphilis (e.g., cranial nerve dysfunction, meningitis, stroke, acute or chronic altered mental status, or loss of vibration sense).

Special Considerations

Parenteral penicillin G is the only therapy with documented efficacy for syphilis during pregnancy. Pregnant women with syphilis at any stage who report penicillin allergy should be desensitized and treated with penicillin (see Management of Persons Who Have a History of Penicillin Allergy).

Management of Sex Partners

Sexual transmission of T. pallidum is thought to occur only when mucocutaneous syphilitic lesions are present. Such manifestations are uncommon after the first year of infection.

What to do if you have syphilis?

If you might have syphilis, your doctor will order a blood test. If this blood test is positive, the lab typically performs a second test on your blood to confirm that you have syphilis. If you have syphilis, you need treatment.

How long does it take to get penicillin for syphilis?

Here’s how you may get the antibiotic: Early stage: One shot of penicillin. Late stage: Three shots of penicillin, with one shot given each week for three weeks. Syphilis affects your nervous system: Penicillin given through an IV (intravenous) infusion, with treatment given once a week for two weeks. To treat syphilis with penicillin, you need ...

How long after syphilis treatment can you have sex?

To treat syphilis with penicillin, you need a shot or IV infusion. Taking penicillin pills cannot cure you. You should not have sex for at least 1 week after treatment and until all symptoms have gone away.

What happens if you catch syphilis in a late stage?

If the syphilis was caught in a late stage, it may have affected your body in other ways. You may need other medical tests. People also need follow-up syphilis blood tests to make sure the syphilis treatment worked. Taking good care of yourself also plays an important role in your treatment.

How long does it take for a bacterial reaction to go away?

It’s possible that the person’s immune system is reacting to the dying bacteria. The reaction clears quickly on its own, usually disappearing completely within 24 hours.

Can you use latex condoms for syphilis?

When you start having sex again, use latex condoms and/or dental dams to prevent getting syphilis again or other sexually transmitted diseases. While the right antibiotic can cure syphilis, it cannot undo damage already done. If syphilis caused hearing loss, you’ll continue to have hearing loss after being treated.

Can you take doxycycline for syphilis?

If your doctor decides to treat you with one of these antibiotics, you will need several follow-up appointments. These antibiotics can be less effective at treating syphilis.

How to get rid of syphilis?

Syphilis is usually super easy to get rid of in the early stages. Your nurse or doctor will prescribe antibiotics to treat the infection — usually penicillin, unless you’re allergic or can’t take it for other reasons. If you’re having syphilis treatment, it’s really important for your sexual partners to get treated also.

What happens if you don't treat syphilis?

Your sexual partners need to be treated, too. If you don’t treat syphilis, it can lead to very serious health problems. X in a circle.

Can syphilis be passed to a baby?

Syphilis can be passed to your fetus during pregnancy or to your baby at birth. This is called congenital syphilis, and it’s very dangerous. Congenital syphilis can lead to stillbirth, birth defects, or infant death. You should be tested for syphilis if you’re pregnant to make sure this doesn’t happen.

Can you pass syphilis back and forth?

If you’re having syphilis treatment, it’s really important for your sexual partners to get treated also. Otherwise, you may pass the infection back and forth, or to other people.

Can you pass syphilis to someone?

Even though syphilis is common and has mild symptoms in the beginning, it can become a really big deal if it’s not treated. You can also easily pass it to other people. Syphilis is easily cured in the early stages. But if you don’t treat syphilis early on, it can get worse and do serious harm to your body in the future.

Can you get syphilis again?

Make sure you both take all of the medicine prescribed to you. Even if you finish your treatment and the syphilis is totally gone, it’s still possible to get a new syphilis infection again if you’re exposed in the future. Syphilis isn’t a one-time-only deal. So use condoms and/or dental dams and get tested regularly.

What is the best treatment for syphilis?

Treatment for syphilis. After determining that you have syphilis, your doctor may give you a single injection of long-acting penicillin if you are still in the primary stages. If you are allergic to penicillin, your doctor may give you antibiotics like doxycycline, azithromycin, or ceftriaxone.

What is syphilis STD?

What is syphilis? Syphilis is a sexually transmitted disease (STD) and the treatment will depend on the stage at which you are diagnosed in. Syphilis is a common infection in people, especially adults, around the world. Consequently, it is important for you to know what it is, and what causes it. This will help you know how to treat it, ...

How long does penicillin last in the hospital?

This medicine is usually given intravenously in a hospital for up to two weeks.

What are the symptoms of secondary syphilis?

After the early symptoms are gone, you will enter the secondary stage. You may start experiencing signs of secondary syphilis which include: A reddish brown rash. White patches in the mouth. Headaches, fever, tiredness, and other flu-like symptoms.

How many groups of people are affected by syphilis?

Symptoms are usually the same for men and women. They can be classified into three groups.

What blood test can be used to test for syphilis?

There are two types of blood tests to prove whether you have a syphilis infection: Nontreponemal tests detect damage to your cells caused by syphilis. Treponemal tests detect antibodies that your body creates to fight syphilis. Both types of tests are needed to confirm a positive diagnosis for syphilis.

How do you get syphilis?

They may appear on your genitals, mouth, or anus. You may get it by engaging in sexual activity with an infected person or by sharing sex toys. Syphilis can be divided into the following stages:

What was the first treatment for syphilis?

The early treatments of syphilis. In the early 16th century, the main treatments for syphilis were guaiacum, or holy wood, and mercury skin inunctions or ointments, and treatment was by and large the province of barber and wound surgeons.

Who discovered syphilis?

In 1913 Joseph Waldron Moore and Hideyo Noguchi isolated the syphilis spirochaete Spirochaeta pallida, which had previously been discovered in 1905 by Fritz Schaudinn, from the brains of people who had died from a condition called “general paralysis of the insane”, establishing syphilis as the cause of this condition.

Why was syphilis so feared?

From its beginning, syphilis was greatly feared by society – because of the repulsiveness of its symptoms, the pain and disfigurement that was endured, the severe after effects of the mercury treatment, but most of all, because it was transmitted and spread by an inescapable facet of human behaviour, sexual intercourse.

When was syphilis first discovered?

Up until the early 20th century it was believed that syphilis had been brought from America and the New World to the Old World by Christopher Columbus in 1493. In 1934 a new hypothesis was put forward, that syphilis had previously existed in the Old World before Columbus.

Where did the word "syphilis" come from?

The name for the disease, ‘syphilis’, originates from an epic Latin poem Syphilis, sive morbus gallicus, ‘Syphilis, or the French disease’ , published in 1530 by Girolamo Fracastoro (L. Hieronymus Fracastorius).

What was the disease that Charles VIII of France caused?

Desiderius Erasmus, 1520. [1] In 1495 an epidemic of a new and terrible disease broke out among the soldiers of Charles VIII of France when he invaded Naples in the first of the Italian Wars, and its subsequent impact on the peoples of Europe was devastating – this was syphilis, or grande verole, the “great pox”.

Who was the first physician to study syphilis?

In 1736 Jean Astruc , a French royal physician and professor of medicine at Montpellier and Paris, wrote one of the first great medical works on syphilis and venereal disease, De Morbus Veneris .

Can syphilis be cured?

Syphilis can be cured with the right antibiotics. However, treatment will not undo any damage that the infection has already caused. If playback doesn't begin shortly, try restarting your device. Videos you watch may be added to the TV's watch history and influence TV recommendations.

Does penicillin kill syphilis?

Treatment will kill the syphilis bacterium and prevent further damage, but it will not repair damage already done. Selection of the appropriate penicillin preparation is important to properly treat and cure syphilis.

Is there a cure for syphilis?

What is the treatment for syphilis? There are no home remedies or over-the-counter drugs that will cure syphilis, but syphilis is easy to cure in its early stages.

Can you take penicillin for syphilis?

Combinations of some penicillin preparations (e.g., Bicillin C-R, a combination of benzathine penicillin and procaine penicillin) are not appropriate treatments for syphilis, as these combinations provide inadequate doses of penicillin.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Syphilis treatment involves antibiotics. Sexual partner should also be treated.
Medication

Antibiotics: Drugs that are used to treat bacterial infections.

Penicillin . Tetracycline . Doxycycline

Self-care

Always talk to your provider before starting anything.

Complete the entire course of medications prescribed.

  • Avoid unsafe sex.
  • Avoid sharing sex toys.
  • Men having unprotected sex with other men are at higher risk.
  • Abstain from sexual contact until infection is cured, including kissing.

Nutrition

Foods to eat:

  • Foods which increase immunity like garlic onions carrots cauliflower and spinach
  • Dry fruits which boosts defence like walnut, almond and pumpkin seeds
  • Blue fish and eggs
  • Whole grain cereals like rice, wheat and oats

Foods to avoid:

  • Soured buttermilk
  • Heavy meals that take long time to digest

Specialist to consult

Infectious disease specialist
Specializes in dealing with the diagnosis, control and treatment of infections.
Primary care physician
Specializes in the acute and chronic illnesses and provides preventive care and health.

Preparing For Your Appointment

Nontreponemal Tests and Traditional Algorithm

  • Medication
    When diagnosed and treated in its early stages, syphilis is easy to cure. The preferred treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin d…
  • Treatment follow-up
    After you're treated for syphilis, your doctor will ask you to: 1. Have periodic blood tests and exams to make sure you're responding to the usual dosage of penicillin. Your specific follow-up will depend on the stage of syphilis you're diagnosed with. 2. Avoid sexual contact with new part…
See more on mayoclinic.org

Treponemal Tests and Reverse Sequence Algorithm

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Cerebrospinal Fluid Evaluation

  • Finding out you have syphilis can be extremely upsetting. You might experience anger if you feel you've been betrayed, or shame if you think you've infected others. However, hold off placing blame. Don't assume that your partner has been unfaithful to you. One (or both) of you may have been infected by a past partner.
See more on mayoclinic.org

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