How is Triple X syndrome diagnosed and treated?
Management and Treatment How is triple X syndrome treated? There is no cure for triple X syndrome. Treatment will depend on the individual symptoms, if any. Given the known association with certain conditions, additional screening tests may be required: Renal ultrasound to look at kidney structure.
Can seizures and kidney abnormalities occur in Triple X syndrome?
How Is Triple X Syndrome Treated? There is no cure for triple X syndrome, but treatments can help with specific symptoms. Finding services early is important and can greatly increase their ability to help your daughter live a healthier, more productive life.
Can I live a normal life with Triple X syndrome?
Aug 26, 2020 · Treatment of Triple X Syndrome Periodic examinations – The doctor may suggest regular screenings. It will allow them to provide you with immediate... Early intervention – These treatment plans comprise different types of therapies, such as speech therapy, physical... Creative learning therapies – If ...
What are the symptoms of Triple X syndrome in babies?
Dec 07, 2020 · Treatment and Medication Options for Triple X Syndrome Genetic Counseling. Women or mothers of women who’ve been diagnosed with triple X syndrome may want to meet with a... Early Intervention. Because babies with trisomy X can have poor muscle tone and motor skills, as well as language and... ...
Can triple X syndrome be treated?
The chromosome error that causes triple X syndrome can't be repaired, so the syndrome itself has no cure. Treatment is based on symptoms and needs. Options that may be helpful include: Periodic screenings.Feb 2, 2022
What is the life expectancy of someone with triple X syndrome?
What is the prognosis for girls and women with triple X syndrome? Girls and women with triple X syndrome can lead normal lives. In many cases, there are no problems with sexual development or fertility. In general, early diagnosis and intervention can help to reduce developmental delays.Oct 16, 2020
What happens when you have triple X syndrome?
Delayed development of speech and language skills, as well as motor skills, such as sitting up and walking. Learning disabilities, such as difficulty with reading, understanding or math. Behavioral problems, such as attention-deficit/hyperactivity disorder (ADHD) or symptoms of autism spectrum disorder.Feb 2, 2022
How do you get triple X syndrome?
It occurs as a random event during cell division in early embryonic development. As a result, some of an affected person's cells have two X chromosomes (46,XX), and other cells have three X chromosomes (47,XXX).Mar 1, 2022
What is the life expectancy of a person with Triple X Syndrome?
This condition does not affect the life expectancy of a person. So, most people with Triple X Syndrome will have the same life expectancy as a pers...
What is Metafemale syndrome?
XXX syndrome is also known as Metafemale syndrome, in which your cells have three X chromosomes instead of two
How does triple X syndrome affect our Body?
The triple X syndrome affects females in different ways. They are:Delay in the development of motor skillsDelay in developing language and speech s...
How long do the symptoms of triple X syndrome disease take to appear?
A majority of females with XXX syndrome are quite healthy with no apparent signs and symptoms of the disease. Therefore, in some cases, this disord...
How can we control the triple X syndrome from spreading?
The triple X syndrome occurs due to a random malfunction when the cells divide, and a girl child receives three X chromosomes (XXX) instead of two...
How many chromosomes are in a 23rd chromosome?
Triple X syndrome happens when a female is born with an extra X chromosome, and therefore has a total of 47 chromosomes . For some girls and women with triple X syndrome, ...
What are the most common disorders that girls with triple X syndrome have?
Attention deficit disorder: It’s more likely that girls with triple X syndrome will have difficulty concentrating in school than girls without triple X syndrome. Mood disorders: Mood disorders most commonly include anxiety and depression.
Why do women get triple X syndrome?
Most cases are caused by errors in chromosome replication and division during the formation of egg or sperm cells, and occur completely by chance. Mothers of advanced maternal age (women who are greater than 35 years old at the time of delivery) appear to be at an increased risk to have a daughter with triple X syndrome.
How many copies of a chromosome are there in a trisomy?
A trisomy is a genetic condition in which there are three copies of a chromosome. Males and females are usually born with 46 chromosomes total, arranged in 23 pairs. One copy of each chromosome in the pair comes from the mother, and the other copy in the pair comes from the father.
What test is used to determine if a person has an extra X chromosome?
These tests can include: Karyotype or chromosome microarray: This is used to assess the person for the presence of an extra X chromosome and to determine the degree of mosaicism (if any).
What are the social problems of triple X syndrome?
Social problems: Girls with triple X syndrome may have problems with communication or social interactions. They may be prone to low self-esteem. Mild cognitive or intellectual impairment: IQ is often in the normal range and typically only 10 to 15 points lower than siblings.
What are the physical characteristics of triple X?
One consistent physical characteristic is that females with triple X are taller than girls of the same age and/or taller than predicted by their parents’ heights. Otherwise, the physical features may be subtle, including: Wide-spaced eyes (known as hypertelorism).
How many chromosomes do girls have?
The chromosomes contain genes, which determine an individual's characteristics, such as eye color and height. Girls typically have two X chromosomes (or XX), but girls with triple X syndrome have an extra X chromosome (XXX).
Why is triple X called triple X?
Girls who have triple X syndrome are born with it. It's called triple X because they have an extra X chromosome in most or all of their cells. Usually, a person has 46 chromosomes in each cell, divided into 23 pairs, which includes two sex chromosomes. Half of the chromosomes are inherited from the father and the other half from the mother.
What is triple X syndrome?
Triple X syndrome is a genetic condition found in females only. About 1 in 1,000 girls have it. Girls with triple X syndrome — also known as XXX syndrome, trisomy X, and 47,XXX, — might be taller than other girls. Other symptoms can include problems with spoken language and processing spoken words, coordination problems, and weaker muscles.
How to help a triple X girl?
Occupational therapy and behavioral therapy can help your daughter develop more confidence and interact better with other children. Counseling. The whole family can benefit from counseling to better understand triple X syndrome and help a girl who has it to live a productive life.
What are the problems that triple X syndrome can cause?
Girls with triple X syndrome can develop speech, learning, or social challenges at a young age. This can make them more likely to have low self-esteem and lead to school or social problems.
What causes triple X?
Triple X is not caused by anything the parents did or did not do. The disorder is a random error in cell division. This error can happen before conception in the reproductive cells of the mother or the father, or early in the embryo's development. When the extra chromosome is due to incorrect cell division in the embryo, ...
What is a curved pinky finger?
very curved pinky finger (called clinodactyly) widely spaced eyes (called hypertelorism) Girls with triple X syndrome also may have delayed development of their social, language, and learning skills. They also can have problems with reading and understanding math, and may have mild delays with coordination.
Why is triple X syndrome called 47,XXX syndrome?
Triple X syndrome is also called 47,XXX syndrome because the extra X chromosome results in 47 chromosomes in each cell instead of the usual 46.
What determines a child's sex?
The pair of sex chromosomes — either XX or XY — determines a child's sex. A mother can give the child only an X chromosome, but a father can pass on an X or a Y chromosome: If the child receives an X chromosome from the father, the XX pair makes the child genetically a female.
How many chromosomes are in triple X syndrome?
Females normally have two X chromosomes in all cells — one X chromosome from each parent. In triple X syndrome, a female has three X chromosomes.
Why is triple X syndrome not inherited?
Causes. Although triple X syndrome is genetic, it's usually not inherited — it's due to a random genetic error. Normally, people have 46 chromosomes in each cell, organized into 23 pairs, including two sex chromosomes. One set of chromosomes is from the mother and the other set is from the father. These chromosomes contain genes, which carry ...
What is the random error that causes an extra X chromosome in a child?
Nondisjunction. In most cases, either the mother's egg cell or the father's sperm cell divides incorrectly, resulting in an extra X chromosome in the child. This random error is called nondisjunction, and all the cells in the child's body will have the extra X chromosome. Mosaic.
What are the symptoms of triple X syndrome?
Signs and symptoms in girls and women with triple X syndrome may include an increased risk of: Delayed development of speech and language skills, as well as motor skills, such as sitting up and walking. Learning disabilities, such as difficulty with reading (dyslexia), understanding or math.
What are the symptoms of autism spectrum disorder?
Behavioral problems, such as attention-deficit/hyperactivity disorder (ADHD) or symptoms of autism spectrum disorder. Psychological problems, such as anxiety and depression. Problems with fine and gross motor skills, memory, judgment and information processing.
What is the meaning of "nondisjunction"?
● Nondisjunction – Incorrect division of the egg cell of the mother or the sperm cell of the father, resulting in an extra X chromosome in the child. If this error occurs, all the cells in the body of the child will have an extra X chromosome.
Is Triple X a chromosomal defect?
As Triple X Syndrome is a chromosomal defect, there is no definite cure for it. The treatment plans depend on symptoms, their severity, and unique requirements. A few of the treatment options include –
Is triple X syndrome severe?
Signs and symptoms of Triple X Syndrome differ from one woman to the other. In some, there are no symptoms at all, while some might show moderate to severe symptoms.
What is triple X syndrome?
Triple X syndrome — also called trisomy X or 47,XXX — is a genetic disorder in which a woman carries an extra X chromosome in each of her cells. Although it’s a genetic disorder, triple X syndrome (which only affects women) is almost never inherited. People have 46 chromosomes in each cell, ...
What is the Axys organization?
Association for X and Y Variations (AXYS) The AXYS is an advocacy, education, and support organization for people and families of people who have Y and Y chromosome variations. It provides support to individuals with the conditions and experts who serve them, as well as champions research and treatment options.
How many chromosomes are in triple X?
Although it’s a genetic disorder, triple X syndrome (which only affects women) is almost never inherited. People have 46 chromosomes in each cell, including one pair of sex chromosomes. Normally, women have two X chromosomes (XX) per cell, while men have one X and one Y chromosome (XY), according to the National Institutes of Health. ...
What is trisomy X?
In most cases, trisomy X occurs when the cells from the mother’s egg or the father’s sperm divide incorrectly, creating an egg or sperm that has an extra X chromosome. In women with mosaicism, the extra chromosome arises from an incorrect cell division that randomly occurs when the embryo (the fertilized egg) develops.
What is the treatment for trisomy X?
Early intervention strategies, like speech therapy, physical therapy, and occupational therapy, can help some girls with trisomy X catch up to their peers or reach their full potential. (5)
What is 47 XYY?
48,XXYY: a chromosome condition in males that results from having an extra X and Y chromosome.
What are the symptoms of premature ovarian failure?
Symptoms of premature ovarian failure include irregular periods, no periods, and trouble getting pregnant. Girls and women with triple X syndrome tend to be more prone to mood disorders like anxiety or depression, and can benefit from counseling and support groups.
What Causes Triple X Syndrome?
Triple X syndrome is congenital, which means that people with the condition are born with it. It affects only females and happens when an extra X chromosome is inherited.
What Are the Symptoms of Triple X Syndrome?
Many girls and women with triple X syndrome have mild symptoms or don’t experience any symptoms at all. People with triple X syndrome that affects all of their cells or a higher percentage of their cells are more likely to have more severe or obvious symptoms.
How Is Triple X Syndrome Diagnosed?
Sometimes, triple X syndrome is diagnosed when a woman has difficulty getting pregnant or experiences early menopause because of ovarian problems.
What Is the Treatment for Triple X Syndrome?
There’s no cure for triple X syndrome, so treatment often depends on each person’s symptoms and needs.
Disease-Specific Communities
Communities, advocacy groups, and support organizations for Triple X syndrome.
General Rare Disease Support Groups
Here are some patient advocacy organizations that support anyone in the rare diseases community.
What is triple X?
Overview. Triple X, also called trisomy X and 47, XXX, is a genetic condition that occurs when a girl receives three X chromosomes from her parents. Typically, girls only receive two X chromosomes. The extra X chromosome can have no effect on a girl’s health, or it can cause physical and mental abnormalities that may range from very mild ...
How to diagnose a fetus?
A diagnosis can be made through genetic testing. This testing can be performed after birth by taking a blood sample. It can also be done before birth by more sophisticated tests like amniocentesis and chorionic villus sampling, which analyze the tissues and cells of a fetus.
What are the symptoms of triple X?
Speech and language delays are other symptoms of triple X. Many with triple X have learning disabilities, involving reading and difficulty with speech and language. A review of studies. found some evidence that girls with triple X may have an IQ about 20 points lower than girls without the disorder.
Why is my triple X baby so slow to walk?
being taller than average (with especially long legs) poor muscle tone. Without strong and developed muscles, babies with triple X may be slow to walk. As they grow older, they may be clumsier than girls without the syndrome.
How many chromosomes are there in a human?
People are usually born with 46 chromosomes, including a pair of sex chromosomes: XY (male) or XX (female). Due to a random malfunction in the way cells split at or right after conception, a girl may receive three X chromosomes, resulting in triple X.
What does extra X chromosomes do to the brain?
Having an extra X chromosome may affect areas of the brain that control what experts#N#Trusted Source#N#call executive functioning. People who don’t have strong executive functioning may find it hard to focus, manage time, and get along with others.
When does menopause stop?
For most women, menopause occurs around age 50. Some research indicates that women with triple X can stop producing eggs at a younger than average age.
What chromosomes do females have?
For female it is the XX chromosomes and males have the XY pair. Genetically, the mother gives the X chromosome while the father has the ability to pass either X or Y chromosome. Then this makes up the sex of the fetus. In the case of Triple X syndrome, there is an additional X chromosome.
What is triple X syndrome?
Triple X is a rare genetic syndrome where there is an addition of X chromosome in a cell of a female. In the genetic makeup, the female genes comprise of XX chromosomes. In a rare occasion, an additional X chromosome or even more is added to the XX pair thus Triple X syndrome happens. This condition is also called as the Trisomy X, 47, ...
Why do women have triple X?
This happens in women because of the additional X chromosome in the pair of XX chromosomes. The chromosomal pair determines the sex of the fetus. For female it is the XX chromosomes and males have the XY pair.
What is epicanthal folds?
Epicanthal folds. This is a condition wherein there are vertical skinfolds in the eyes which can cover the eye corners. Delayed development of speech or language as well as motor skills- fine motor and gross motor skills. Speech problems like being dyslexic.
Why is it called 47?
This condition is also called as the Trisomy X, 47, Triplo-X or XXX aneuploidy. This is called as 47 because conventionally there are 46 chromosomes in the body. With the addition of 1 chromosome, it is then called as 47.
What happens when an egg cell is incorrectly formed?
What happens is that the egg cell or the sperm cell is incorrectly formed thus an addition of X chromosome is formed . This process is called as the nondisjunction. The addition of extra chromosome usually happens in the first few stages of the embryonic development or when the embryo is still in the process of developing.
Why are problems associated with the developmental stages of the child as compared to the physical manifestations?
This is because the anomaly in the physical aspect is seldom observed in patients with triple X.
