Medication
In many cases, the best Peyronie’s disease treatment is surgery. There are primarily two different types of surgery, with Dr. Gelman advising the patient to undergo either a penile plication or penile graft surgery. Successful surgery will correct any noticeable signs of curvature, allowing for normal sexual intercourse.
Procedures
Most Peyronie’s specialists initiate treatment with medical therapy, usually pills or topical creams to the penis. The history of pill therapy for Peyronie’s includes many drugs, most non-FDA approved. Many specialists prescribe pentoxyphyline, a drug initially used to improve blood flow to the legs of patients with vascular insufficiency.
Nutrition
Some doctors use a drug called verapamil. Studies show it can decrease the curve and pain in many men. Collagenase clostridium histolyticum ( Xiaflex) is another injected drug for treating...
What treatment do you recomend for Peyronies disease?
Apr 20, 2022 · Peyronie’s disease is one of the most underconsultated medical ailments, which most men would keep undercover due to the social stigma. There are various ways to treat this disorder, but a penis stretcher/ penis extender is the most popular of all.
Are there any ways to cure Peyronies disease?
What can be done to help with Peyronie's disease?
What does it mean to "cure" Peyronie's disease?
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How to cure Peyronie's disease?
In many cases, the best Peyronie’s disease treatment is surgery. There are primarily two different types of surgery, with Dr. Gelman advising the patient to undergo either a penile plication ...
What is pentoxifylline used for?
Pentoxifylline is a medication that has been used for many years for the treatment of intermittent leg cramping (claudication). It has gained recent attention as a potentially effective Peyronie’s disease treatment. Trental is now at the Center for Reconstructive Urology what Vitamin E was 20 years ago at our Center.
Does Vitamin E help with peyronies?
For decades, Vitamin E has been commonly prescribed Peyronie’s disease treatment because it is inexpensive and can be an effective treatment for scarring (of the skin).
Is Verapamil a tablet?
Unlike the other treatments listed above, Verapamil is not a tablet or pill. Rather, it is Peyronie’s disease treatment that is applied as a topical cream, but also can be injected directly into the penis. Verapamil is a calcium inhibitor that is often used to treat hypertension. It is thought that the this medication may alter fibroblast function. Fibroblast cells are involved in wound healing after tissue injury. It is called “transdermal” as supposedly, the medication can travel through the skin into the plaque leading to a beneficial change. Certainly this medication is effective in increasing the income of those who promote and sell this drug. However, there is no clearly established proven efficacy for this medicaiton being a Peyronie’s Disease cure or effective treatment in the peer-reviewed published literature.
What is penis curvature?
Penile curvature is generally related to the development of a dense inelastic plaque within the penis. In order for creams, pills or other treatments to be effective, they need to change the affected tissue from a dense scar back to elastic, supple, and healthy tissue.
How does Potaba work?
This medication is composed of potassium p-aminobenzoate and is considered an antifibrotic medication, which means that Potaba is thought to prevent fibrosis (scarring) by increasing oxygen uptake at the tissue level. In order for the medication to be effective, patients are required to take large doses every day for months at a time. The recommended daily dose is 4 (0.5gram) tablets or 6 capsules, and the number of pills patients are asked to take discourages many from going with this Peyronie’s treatment. This medication was popular in the 1990s but is no longer in use.
Who makes Xiaflex?
The manufacturer was Auxillium (now owned by Endo Pharmaceuticals). Xiaflex is a medication that is injected into the plaque inside the penis. Prior to Xiaflex injection, a different medication is injected into the penis to produce an erection to identify the area of maximum curvature, and that is marked.
What is the treatment for Peyronie's disease?
Medical Management for Peyronie's Disease. Most Peyronie’s specialists initiate treatment with medical therapy, usually pills or topical creams to the penis. The history of pill therapy for Peyronie’s includes many drugs, most non-FDA approved. Many specialists prescribe pentoxyphyline, a drug initially used to improve blood flow to the legs ...
What is Xiaflex injection?
Xiaflex, collagenase, is a biological agent that a urologist injects directly into the plaque. The enzyme digests the abnormal collagen deposits in the plaque to decrease the abnormal force exerted on the penis.
Is Xiaflex an intralesional therapy?
Interferon injections have also been used with similar success. Neither of these therapies is FDA approved. However, as of 2013, Xiaflex received FDA approval as an intralesional therapy. Xiaflex, collagenase, is a biological agent that a urologist injects directly into the plaque. The enzyme digests the abnormal collagen deposits in the plaque to decrease the abnormal force exerted on the penis. Men in clinical studies had a roughly 40% improvement in their curvature and reported improvements in their distress suffered from the disease. Side effects of this therapy were usually mild and included temporary pain, bruising and swelling. A few men in the clinical trials had a penile injury severe enough to need surgical correction. All of these men regained sexual function post surgery. Dr. Mills at The Men's Clinic at UCLA is a national leader in using Xiaflex, the first drug to be approved by the U.S. Food and Drug Administration (FDA) for the treatment of Peyronie's Disease.
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