Treatment for hyperphosphatemia will depend on the underlying cause:
- If a person has uncontrolled diabetes, it is essential to bring this under control with diet, exercise, and a medicine called insulin.
- A person with the hormone disorder hypoparathyroidism may need to take a supplement. ...
- When kidney disease causes hyperphosphatemia, a combination of changes to diet and medication is usually used to treat it. ...
What are the signs and symptoms of hyperphosphatemia?
These generally are uremic symptoms, such as the following:
- Fatigue
- Shortness of breath
- Anorexia
- Nausea
- Vomiting
- Sleep disturbances
How do you treat high phosphate levels?
Steps you can take to manage your phosphorus levels include:
- Take a phosphate binder This is a pill you take with meals Keeps your body from absorbing the phosphorus from foods and drinks Help keep phosphorus from building up in ...
- Limit how much phosphorus you eat and drink each day. ...
- Take a calcitriol supplement. ...
- Exercise and increase your daily activity. ...
- Do not smoke or use tobacco.
What are the dangers of excess phosphorus?
Phosphorus is an essential element for plant life, but when there is too much of it in water, it can speed up eutrophication (a reduction in dissolved oxygen in water bodies caused by an increase of mineral and organic nutrients) of rivers and lakes.
What can cause hyperphosphatemia?
Renal failure is the most common cause of hyperphosphatemia. A glomerular filtration rate of less than 30 mL/min significantly reduces the filtration of inorganic phosphate, increasing its serum level. Other less common causes include a high intake of phosphorus or increased renal reabsorption.
Which medication is most commonly used to treat hyperphosphatemia?
Sevelamer is the most commonly prescribed non-calcium-based phosphate binder, but has a lower phosphate-binding capacity than other phosphate binders.
What medications reduce hyperphosphatemia?
Sevelamer hydrochloride (Renagel, Renvela) The polymer forms ionic and hydrogen bonds with phosphates and bile acids to promote fecal excretion. It lowers serum phosphate to near normal levels in hemodialysis patients as effectively as calcium acetate without inducing hypercalcemia or increased aluminum levels.
What oral treatment can be used for hyperphosphatemia?
Ferric Citrate: Ferric citrate (Auryxia) is an oral iron-based phosphate binder that was approved by the FDA in 2014 for management of hyperphosphatemia in patients with CKD on dialysis. Upon ingestion, this product dissociates into its ferric iron and citrate components.
What is the treatment for hypophosphatemia?
In chronic hypophosphatemia, standard treatment includes oral phosphate supplementation and active vitamin D. Future treatment for specific disorders associated with chronic hypophosphatemia may include cinacalcet, calcitonin, or dypyrimadole.
What drugs are phosphate binders?
Which medications in the drug class Phosphate Binders are used in the treatment of Hyperphosphatemia?Phosphate Binders. ... Lanthanum carbonate (Fosrenol) ... Sucroferric oxyhydroxide (Velphoro) ... Ferric citrate. ... Aluminum hydroxide. ... Calcium carbonate (Caltrate 600, Os-Cal, Tums, Oysco 500)More items...•
What is the most common cause of hyperphosphatemia?
Renal failure is the most common cause of hyperphosphatemia. A glomerular filtration rate of less than 30 mL/min significantly reduces the filtration of inorganic phosphate, increasing its serum level. Other less common causes include a high intake of phosphorus or increased renal reabsorption.
What happens in hyperphosphatemia?
When you have hyperphosphatemia, the phosphate levels in your body become very high. Your kidneys are supposed to excrete 90% of your daily phosphate load. Your gastrointestinal tract excretes the remaining phosphate. When you have kidney problems, your phosphate levels can't be regulated.
What is severe hyperphosphatemia?
Severe hyperphosphatemia, defined herein as levels of 14 mg/dL or higher, is almost invariably multifactorial--usually resulting from addition of phosphorus to the extracellular fluid together with decreased phosphorus excretion.
What are natural phosphate binders?
Currently, the commonly used phosphate binders are calcium carbonate, calcium acetate, sevelamer hydrochloride, lanthanum carbonate, and magnesium hydroxide. These binders are reasonably safe and moderately bind dietary phosphates.
What is the nursing intervention for hyperphosphatemia?
Nursing interventions for both hypophosphatemia and hyperphosphatemia include the following: monitor serum phosphorus and calcium levels. review the patient's medication administration record for any drugs that may affect the phosphorus or calcium level.
How do you fix phosphorus levels?
Treatment of hypophosphatemia is twofold: (1) correct any precipitating causes of hypophosphatemia, and (2) replace total body phosphates. Depending on the clinical situation, replacement options include dietary phosphate, oral phosphate preparations, and IV phosphate.
Who treats hypophosphatemia?
A nephrologist can help confirm the likelihood of phosphate wasting and can help assess the patient for causes of renal phosphate wasting.
What causes hyperphosphatemia?
Hyperphosphataemia can be induced by three main conditions: a massive acute phosphate load, a primary increase in renal phosphate reabsorption, and an impaired renal phosphate excretion due to acute or chronic renal insufficiency.
How long does it take for hyperphosphataemia to resolve?
Therefore, acute hyperphosphataemia usually resolves within few hours if renal function is intact.
What are non-calcium based phosphate binders?
At present, there are three types of non-calcium-based phosphate binders available: sevelamer, lanthanum carbonate and magnesium salts.
Is calcium salt good for hypercalcemia?
Calcium-based salts are inexp ensive, effective and most widely used, but there is now concern about their association with hypercalcaemia, parathyroid gland suppression, adynamic bone disease, and vascular and extraosseous calcification.
What is the best treatment for hyperphosphatemia?
Medication or supplements containing calcium may be recommended for treating and preventing hyperphosphatemia. Treatment for hyperphosphatemia will depend on the underlying cause: If a person has uncontrolled diabetes, it is essential to bring this under control with diet, exercise, and a medicine called insulin.
How to prevent hyperphosphatemia?
The main way to prevent hyperphosphatemia is to control the levels of phosphate and calcium in the body. This is usually done by eating certain foods and avoiding others. Processed foods often contain phosphorus as a preservative, shown by ingredients that have the letters PHOS together.
What causes high phosphate levels?
There are other conditions linked with high levels of phosphate in the blood, however, including the following: 1 Uncontrolled diabetes: This causes high levels of blood sugar that can lead to serious medical problems, such as organ damage. 2 Diabetic ketoacidosis: A complication of diabetes that can happen if the body begins to run out of insulin. Harmful ketones build up in the body and blood sugar levels rise. 3 Hypoparathyroidism: A rare hormone disorder in which the body does not produce enough parathyroid hormone (PTH). PTH helps control the levels of phosphorus in the blood and bones. 4 Hypocalcemia: Low levels of calcium in the blood.
What is the effect of phosphates on the kidneys?
The kidneys naturally control levels of phosphates. However, if the kidneys are not working efficiently, they may not be able to remove enough phosphate, leading to high levels in the body. Treatment for hyperphosphatemia will depend on the underlying condition.
What is the chemical that makes up phosphate?
Phosphate is a chemical found in the body. It contains a mineral called phosphorus that occurs naturally in many foods. Phosphorus supports bones and teeth to develop and helps turn food into energy for the body to use. The kidneys naturally control levels of phosphates.
What is phosphate binder?
The primary aim is to prevent further damage to bones. A phosphate binder is a medication containing calcium.
What is too much phosphate in the blood called?
Treatment. Prevention. Outlook. Too much phosphate in the blood is known as hyperphosphatemia. The most common cause is kidney disease, but other conditions can lead to phosphate levels being out of balance. Phosphate is a chemical found in the body. It contains a mineral called phosphorus that occurs naturally in many foods.
What happens if you have hyperphosphatemia?
If your hyperphosphatemia is left untreated, you may be at risk of developing other life-threatening conditions. These include the following: 1 Secondary hyperparathyroidism 2 Renal osteodystrophy, a bone disease caused by kidney failure 3 Metastatic calcification, or deposition of calcium, in blood vessels and soft tissue
Can CKD cause high phosphorus levels?
Properly functioning kidneys remove extra phosphorus that ends up in your body. But with CKD, your kidneys can’t remove the phosphorus, causing it to build up in your body. High levels of phosphorus can damage your body.#N#
What is hyperphosphatemia?
Hyperphosphatemia is a condition that arises from elevated phosphate levels in your bloodstream. It may be something that you have never considered or even realized was possible for your body. But it can happen, and it could do some serious damage to your system.
Why do doctors check for hyperphosphatemia?
These blood tests will look at: It should be noted that doctors may consider hyperphosphatemia early on if you have had issues with your kidneys in the past. Kidney disease, failure, and transplantation often come with high phosphate levels in the blood, as the kidneys help process phosphates in your body.
How to lower phosphate levels?
Changing your diet to foods containing fewer phosphates can help lower the overall amount in your body. You can also avoid foods that have high phosphate content. If you are trying to lower your phosphate levels, try avoiding the following foods: 1 Whole grains 2 Chocolate 3 Dairy products like milk, ice cream and cheese (cottage cheese and cream cheese are okay) 4 Organ meats 5 Dark cola drinks 6 Certain types of fish like pollock, sardines, and walleye 7 Vegetables and legumes (artichoke, asparagus, broccoli, beans, corn, lentils, mushrooms, pumpkin, parsnip, spinach, and sweet potato)
What blood test is used to detect hyperphosphatemia?
In the case of hyperphosphatemia, blood tests are best for detecting the higher phosphate levels within the bloodstream. These blood tests will look at: Vitamin D. Phosphate. Calcium.
Does hyperphosphatemia right itself?
So in the cases of things like injury or trauma to the body , once they are treated, the phosphate levels in your bloodstream will frequently right themselves on their own.
Can hyperphosphatemia be treated with drugs?
And you will no longer have to worry about hyperphosphatemia. However, for certain issues or when there is no identifiable underlying cause, treatment for hyperphosphatemia may include certain drugs. For example, there are a number of drugs known as phosphate binders that basically prevent your body from absorbing phosphate.
Can high phosphate levels be life threatening?
Having high phosphate levels in your body sounds like a severe issue, and don’t get us wrong, higher levels of phosphate in your system can be life-threatening if left untreated. That being said, hyperphosphatemia is easily treated, especially if you are targeting its underlying cause.
