Treatment FAQ

what is the treatment for esophageal cancer

by Grover Cormier Published 2 years ago Updated 2 years ago
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Surgery is the most common treatment for cancer of the esophagus. Part of the esophagus may be removed in an operation called an esophagectomy. Esophageal stent. A device (stent) is placed in the esophagus to keep it open to allow food and liquids to pass through into the stomach.Nov 18, 2021

Medication

7 rows · Jul 15, 2021 · Table 12. Standard Treatment Options for Esophageal Cancer; Stage (TNM Staging Criteria) ...

Procedures

Options for treatment typically include endoscopic treatments such as photodynamic therapy (PDT), radiofrequency ablation (RFA), or endoscopic mucosal resection (EMR). Long-term follow-up with frequent upper endoscopy is very important after endoscopic treatment to continue to look for pre-cancer (or cancer) cells in the esophagus.

Therapy

Nov 18, 2021 · Patients have special nutritional needs during treatment for esophageal cancer. Seven types of standard treatment are used: Surgery ; Radiation therapy Chemotherapy ; Chemoradiation therapy; Laser therapy Electrocoagulation Immunotherapy; New types of treatment are being tested in clinical trials. Targeted therapy

Nutrition

Feb 08, 2022 · Esophageal Cancer Treatments, Molecular Testing, and Overall Approach Your or your loved one’s esophageal cancer will likely be treated with various combinations of surgery, radiation therapy (aiming intense beams of energy at tumors to kill them), and medications known as chemotherapy, targeted therapy, and immunotherapy.

What are the best methods for treating esophageal cancer?

Treatments for recurrent esophageal cancer include surgery, chemoradiation, laser and targeted therapy. Learn about treatment options. Learn more Surgery for esophageal cancer Surgery is often used to treat esophageal cancer. Learn about esophagectomy and other types of surgery used to treat esophageal cancer. Learn more

How do I choose the best esophageal cancer treatment?

You can contact MyPART for help finding experts near you. Treatment options to discuss with your doctor include: Surgery: Surgery is used to remove as much of the esophageal cancer as possible. Radiation therapy: Radiation therapy uses high energy x-rays or other types of radiation to kill the cancer cells.

What is life expectancy for Stage 4 esophageal cancer?

Can you cure esophageal cancer?

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Does esophageal cancer spread quickly?

Esophageal cancer grows slowly and may grow for many years before the symptoms are felt. However, once the symptoms develop, esophageal cancer progresses rapidly. As the tumor grows, it can seep into the deep tissues and organs near the esophagus.Apr 22, 2021

Is esophagus cancer treatable?

Esophageal cancer or cancer of the food pipe is an aggressive cancer. In most cases, esophageal cancer is a treatable disease, although cure rates are low.Apr 19, 2021

How long is the treatment for esophageal cancer?

Adjuvant or neoadjuvant chemo is often given for a total of 3 to 6 months, depending on the drugs used. The length of treatment for advanced esophageal cancer depends on how well it is working and what side effects you might have.Mar 20, 2020

What is the main cause of esophageal cancer?

It's thought that chronic irritation of your esophagus may contribute to the changes that cause esophageal cancer. Factors that cause irritation in the cells of your esophagus and increase your risk of esophageal cancer include: Having gastroesophageal reflux disease (GERD) Smoking.Oct 13, 2020

What were your first signs of esophageal cancer?

The most common symptoms of esophageal cancer are:Trouble swallowing.Chest pain.Weight loss.Hoarseness.Chronic cough.Vomiting.Bone pain (if cancer has spread to the bone)Bleeding into the esophagus. This blood then passes through the digestive tract, which may turn the stool black.Mar 20, 2020

How long can you live with cancer of the esophagus?

It also means that people with esophageal cancer are 47 percent as likely as people without esophageal cancer to live five years or more....5 Year Survival Rate by Stage.SEER Stage*Five-year Survival Rate (in percentage)All SEER stages combined20Localized47Regional25Distant5

Can you beat esophageal cancer?

There are many ways to treat esophagus cancer: Surgery and radiation therapy are mainly used to treat only the cancer. They do not affect the rest of the body. Chemotherapy and targeted therapy and immunotherapy go through the whole body.Mar 20, 2020

Can esophageal cancer be removed?

Esophagectomy is the main surgical treatment for esophageal cancer. It is done either to remove the cancer or to relieve symptoms. During an open esophagectomy, the surgeon removes all or part of the esophagus through an incision in the neck, chest or abdomen.Mar 5, 2022

What are the final stages of esophageal cancer?

The signs of dying from esophageal cancer include greater difficulty swallowing (dysphagia), as well as symptoms common to other types of cancers, such as: fatigue. onset of pain. breathing troubles.Mar 27, 2020

Where does esophageal cancer usually start?

The cancer starts at the inner layer of the esophagus and can spread throughout the other layers of the esophagus and to other parts of the body (metastasis). There are two main types of esophageal cancer. One type is squamous cell carcinoma.Jan 20, 2022

Does esophageal cancer show up in blood work?

Certain blood tests can also be used to help a physician confirm an esophageal cancer diagnosis. For instance, a blood test can be used to detect anemia or check liver function; esophageal cancer can sometimes cause anemia if the tumor bleeds, and it may impact liver function if the cancer spreads.

How long does it take esophageal cancer to develop?

The cells lining the esophagus in that area can become irritated from being exposed to foods for longer than normal amounts of time. People with achalasia have a risk of esophageal cancer that is many times normal. On average, the cancers are found about 15 to 20 years after the achalasia began.Jun 9, 2020

Treating Stage 0 Esophagus Cancer

A stage 0 tumor is not true cancer. It contains abnormal cells called high-grade dysplasia and is a type of pre-cancer. The abnormal cells look lik...

Treating Stage I Esophagus Cancer

In this stage the cancer has grown into some of the deeper layers of the esophagus wall (past the innermost layer of cells) but has not reached the...

Treating Stages II and III Cancer of The Esophagus

Stage II includes cancers that have grown into the main muscle layer of the esophagus or into the connective tissue on the outside of the esophagus...

Treating Stage IV Cancer of The Esophagus

Stage IV esophageal cancer has spread to distant lymph nodes or to other distant organs.In general, these cancers are very hard to get rid of compl...

How long does esophageal cancer last?

The survival rate of patients with esophageal cancer is poor. Surgical treatment of resectable esophageal cancers results in 5-year survival rates of 5% to 30%, with higher survival rates in patients with early-stage cancers. [ 7] .

What is the median age for esophageal cancer?

In the United States, the median age of patients who present with esophageal cancer is 68 years. [ 6] . Most adenocarcinomas are located in the distal esophagus. The cause for the rising incidence and demographic alterations is unknown.

Which neoplasms are most common in the esophagus?

Related Summaries. Two histologic types account for the majority of malignant esophageal neoplasms: adenocarcinoma and squamous cell carcinoma. Adenocarcinomas typically start in the lower esophagus and squamous cell carcinoma can develop throughout the esophagus. The epidemiology of these types varies markedly.

What are the risk factors for squamous cell carcinoma of the esophagus?

Risk factors for squamous cell carcinoma of the esophagus include: Tobacco. Alcohol. Risk factors associated with esophageal adenocarcinoma are less clear. [ 3] . Barrett esophagus is an exception and its presence is associated with an increased risk of developing adenocarcinoma of the esophagus.

Is palliation a problem for esophageal cancer patients?

Palliation presents difficult problems for all patients with recurrent esophageal cancer. All patients should be considered candidates for clinical trials as outlined in the Treatment Option Overview for Esophageal Cancer section of this summary.

What is AJCC staging?

The AJCC has designated staging by TNM (tumor, node, metastasis) classification to define cancer of the esophagus and esophagogastric junction. [ 13] Tumors located in the gastric cardia within 5 cm of the gastroesophageal junction with extension into the esophagus or the gastroesophageal junction are classified as esophageal cancer. Tumors with the epicenter of the tumor located in the gastric cardia beyond 5 cm of the gastroesophageal junction or without extension into the esophagus are classified as gastric cancer. [ 13] (Refer to the Stage Information for Gastric Cancer section in the PDQ summary on Gastric Cancer Treatment for more information.)

Is PDQ cancer information updated?

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

What is the best treatment for esophagus cancer?

Options for treatment typically include endoscopic treatments such as photodynamic therapy (PDT), radiofrequency ablation (RFA), or endoscopic mucosal resection (EMR). Long-term follow-up with frequent upper endoscopy is very important after endoscopic treatment to continue to look for pre-cancer (or cancer) cells in the esophagus.

Where are abnormal cells found in the esophagus?

The abnormal cells look like cancer cells, but they are only found in the inner layer of cells lining the esophagus (the epithelium). They have not grown into deeper layers of the esophagus. This stage is often diagnosed when someone with Barrett’s esophagus has a routine biopsy. Options for treatment typically include endoscopic treatments such as ...

What is the treatment for cancer in the neck?

If the cancer is in the upper part of the esophagus (in the neck), chemoradiation may be recommended as the main treatment instead of surgery.

Is it hard to cure cancer?

In general, these cancers are very hard to get rid of completely, so surgery to try to cure the cancer is usually not a good option. Treatment is used mainly to help keep the cancer under control for as long as possible and to relieve any symptoms it is causing.

What is stage 3 cancer?

Stage III includes some cancers that have grown through the wall of the esophagus to the outer layer, as well as cancers that have grown into nearby organs or tissues. It also includes most cancers that have spread to nearby lymph nodes.

Can cancer come back in the esophagus?

If the cancer was initially treated endoscopically (such as with endoscopic mucosal resection or photodynamic therapy), it most often comes back in the esophagus. This type of recurrence is often treated with surgery to remove the esophagus. If the patient isn’t healthy enough for surgery, the cancer may be treated with chemotherapy, radiation, ...

What does it mean when a tumor comes back?

Recurrent means the cancer has come back after treatment . The recurrence may be local (near the area of the initial tumor), or it may be in distant organs. Treatment of esophageal cancer that comes back (recurs) after initial treatment depends on where it recurs and what treatments have been used, as well as a person’s health and wishes for further treatment.

What are the symptoms of esophageal cancer?

Signs and symptoms of esophageal cancer are weight loss and painful or difficult swallowing. Tests that examine the esophagus are used to diagnose esophageal cancer. Certain factors affect prognosis (chance of recovery) and treatment options.

Why is it so hard to eat with esophageal cancer?

Many people with esophageal cancer find it hard to eat because they have trouble swallowing. The esophagus may be narrowed by the tumor or as a side effect of treatment. Some patients may receive nutrients directly into a vein. Others may need a feeding tube (a flexible plastic tube that is passed through the nose or mouth into the stomach) until they are able to eat on their own.

How does chemo work?

When chemotherapy is taken by mouth or injected into a vein or muscle , the drugs enter the bloodstream and can reach cancer cells throughout the body ( systemic chemotherapy ). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas ( regional chemotherapy ). The way the chemotherapy is given depends on the type and stage of the cancer being treated.

Where is squamous cell carcinoma found?

This cancer is most often found in the upper and middle part of the esophagus, but can occur anywhere along the esophagus. This is also called epidermoid carcinoma.

Why do we do clinical trials?

Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.

What is the esophagus made of?

The wall of the esophagus is made up of several layers of tissue , including mucous membrane, muscle, and connective tissue.

Where does adenocarcinoma form?

Adenocarcinomas usually form in the lower part of the esophagus, near the stomach.

How does esophageal cancer surgery work?

During esophagectomy, your surgeon removes the portion of your esophagus that contains the tumor, along with a portion of the upper part of your stomach, and nearby lymph nodes. The remaining esophagus is reconnected to your stomach. Usually this is done by pulling the stomach up to meet the remaining esophagus.

What is the stage of esophageal cancer?

The stages of esophageal cancer are indicated by Roman numerals that range from 0 to IV, with the lowest stages indicating that the cancer is small and affects only the superficial layers of your esophagus. By stage IV, the cancer is considered advanced and has spread to other areas of the body.

Why do you need a feeding tube?

Providing nutrition. Your doctor may recommend a feeding tube if you're having trouble swallowing or if you're having esophagus surgery. A feeding tube allows nutrition to be delivered directly to your stomach or small intestine, giving your esophagus time to heal after cancer treatment.

What is the camera on the end of an endoscope?

A tiny camera on the end of the endoscope lets your doctor examine your esophagus, stomach and the beginning of your small intestine (duodenum). Tests and procedures used to diagnose esophageal cancer include: Barium swallow study. During this study, you swallow a liquid that includes barium and then undergo X-rays.

Where does radiation come from?

Radiation typically will come from a machine outside your body that aims the beams at your cancer (ex ternal beam radiation). Or, less commonly, radiation can be placed inside your body near the cancer (brachytherapy). Radiation therapy is most often combined with chemotherapy in people with esophageal cancer.

What is the purpose of a scope in an endoscopy?

Using a scope to examine your esophagus (endoscopy). During endoscopy, your doctor passes a flexible tube equipped with a video lens (videoendoscope) down your throat and into your esophagus. Using the endoscope, your doctor examines your esophagus, looking for cancer or areas of irritation.

How to treat esophageal obstruction?

If your esophageal cancer has narrowed your esophagus, a surgeon may use an endoscope and special tools to place a metal tube (stent) to hold the esophagus open.

Treatments for stage 0 esophageal cancer

A number of treatments may be used for stage 0 esophageal cancer. Learn about treatments, including surgery, EMR, PDT and radiofrequency ablation.

Treatments for stage 1 esophageal cancer

A number of treatments may be used for stage 1 esophageal cancer. Learn about treatment options, including surgery, EMR, chemoradiation and chemotherapy.

Treatments for stage 2 esophageal cancer

A number of treatments may be used for stage 2 esophageal cancer. Learn about treatments, including surgery, chemoradiation and chemotherapy.

Treatments for stage 3 esophageal cancer

Different treatments may be used for stage 3 esophageal cancer. Learn about treatments, including surgery, chemoradiation and chemotherapy.

Treatments for stage 4 esophageal cancer

Treatments for stage IV esophageal cancer can relieve symptoms and improve quality of life. Learn about surgery, radiation, laser and other treatments used.

Treatments for recurrent esophageal cancer

Treatments for recurrent esophageal cancer include surgery, chemoradiation, laser and targeted therapy. Learn about treatment options.

Surgery for esophageal cancer

Surgery is often used to treat esophageal cancer. Learn about esophagectomy and other types of surgery used to treat esophageal cancer.

What is the best treatment for esophageal cancer?

Surgery: Surgery is used to remove as much of the esophageal cancer as possible. Radiation therapy: Radiation therapy uses high energy x-rays or other types of radiation to kill the cancer cells. Chemotherapy: Chemotherapy uses anti-cancer drugs to kill the cancer cells. Chemotherapy is used when the cancer cells have spread to other parts ...

What are the symptoms of esophageal cancer?

Weight loss for no known reason. Hiccups. Throwing up with streaks of blood. Streaks of blood in mucus coughed up from the lungs. Imaging: If you have symptoms of esophageal cancer, your doctor will use imaging scans such as a Barium Swallow, CT, PET, and ultrasound to see where the tumor is and how big it is.

How does cancer affect you?

The estimate of how a disease will affect you long-term is called prognosis. Each person is different and prognosis will depend on many factors, such as: 1 Where the tumor is in your body 2 If the cancer has spread to other parts of your body 3 How much of the tumor is taken out during surgery

What are the two most common types of esophageal cancer?

It is part of the digestive system. The two most common types of esophageal cancer are adenocarcinoma and squamous cell carcinoma. Esophageal adenocarcinoma forms in the glandular cells. These cells are in the lining of the esophagus and make fluids, such as mucus. Esophageal squamous cell carcinoma forms in the squamous cells in the esophagus.

How long does esophageal cancer last?

The overall five-year survival rate for esophageal cancer is about 20%, but survival rates can range from 5% to 47%. When esophageal cancer is found early and when it is small, the five-year survival rate is higher.

When is chemotherapy used?

Chemotherapy is used when the cancer cells have spread to other parts of the body. Targeted therapy: Targeted therapy is aimed at the changes in cancer cells that help them grow, divide, and spread.

Is esophageal cancer rare?

Esophageal cancer is a rare type of cancer, making up about 1% of cancer cases in the United States. The rate of new cases per year is about 4 for every 100,000 people. In other parts of the world, esophageal cancer is more common. In the United States, esophageal adenocarcinoma is more common than esophageal squamous cell carcinoma ...

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Diagnosis

Treatment

Clinical Trials

Alternative Medicine

Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves removal of tumor through surgery, chemotherapy or radiation.
Medication

Chemotherapy: Drugs to kill the cancer cells and can be used at different times during treatment. Often as a combination with radiation therapy.

Carboplatin/Paclitaxel . Cisplatin/5-Fluorouracil (5-FU) . Epirubicin/Cisplatin/5-FU (ECF) . Docetaxel/ Cisplatin/5-FU (DCF)

Procedures

Tumor excision: To remove the small tumors which are confined to the superficial layers of esophagus.

Esophagectomy: A portion of esophagus which contains tumor is removed, and the remaining esophagus is reconnected to the stomach.

Esophagogastrectomy: Surgery to remove part of esophagus and the upper portion of stomach.

Electrocoagulation: Electric current is used to destroy the cancer cells.

Therapy

Radiation therapy:High-powered energy from X-rays and protons are used to destroy cancer cells and shrink tumors.

Photodynamic therapy:High-intensity laser light is used to destroy superficial tumors.

Nutrition

Foods to eat:

  • Soft foods such as pudding, applesauce, ice cream, bananas, smoothies
  • Liquid foods like soups and broths

Foods to avoid:

  • Citrus fruits like oranges, lemon
  • Tomatoes and tomato-based foods
  • Spicy foods
  • Fried dishes
  • Alcohol and drinks with carbonation

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Gastroenterologist
Specializes in the digestive system and its disorders.

Coping and Support

Preparing For Your Appointment

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