Treatment FAQ

what is the treatment for childhood leukemia

by Prof. Amiya Mitchell Published 3 years ago Updated 2 years ago
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The main treatment for most childhood leukemias is chemotherapy. For some children with higher risk leukemias, high-dose chemotherapy may be given along with a stem cell transplant. Other treatments might also be used in special circumstances.

What is the expected lifespan of a child with leukemia?

How is childhood leukemia treated? Surgery for Childhood Leukemia Radiation Therapy for Childhood Leukemia Chemotherapy for Childhood Leukemia Targeted Therapy Drugs for Childhood Leukemia Immunotherapy for Childhood Leukemia High-dose Chemotherapy and Stem Cell Transplant for Childhood Leukemia

Can childhood leukemia be cured?

The main treatment for most childhood leukemias is chemotherapy. For some children with higher risk leukemias, high-dose chemotherapy may be given along with a stem cell transplant. Other treatments might also be used in special circumstances.

What are the early signs of childhood leukemia?

Pediatric Leukemia: Chemotherapy, Radiation, and Bone Marrow Transplants MSK Kids offers all of the treatments available for pediatric leukemia. Learn what you and your child can expect. Pediatric Leukemia: CAR T Cell Therapy for Children, Teens, and Young Adults Read about chimeric antigen receptor (CAR) T cell therapy, an innovative form of immunotherapy at MSK …

What is the most common leukemia in children?

Mar 25, 2022 · Possible treatments might include: chemotherapy radiation therapy Chemotherapy with stem cell transplant Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells

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What is the survival rate for childhood leukemia?

Children. According to the Leukemia and Lymphoma Society (LLS), the average 5-year survival rate for ALL, the most common type of leukemia in children, is 94.4 percent for those under age 5. There's a slight drop to 92.5 percent for older children under age 15.Nov 24, 2021

Can you be cured from childhood leukemia?

Most childhood leukemias have very high remission rates, with some up to 90%. Remission means that doctors see no cancer cells in the body. Most kids are cured of the disease. This means that they're in permanent remission.

How long does leukemia treatment last for children?

Treatment typically takes two to three years to complete. Our oncologists, nurses, radiologists, psychologists, and wellness experts provide support for your family—from medical care to emotional and logistical assistance—during and after treatment.

What is the most common age for childhood leukemia?

ALL is most common in early childhood, peaking between 2 and 5 years of age. AML tends to be more spread out across the childhood years, but it's slightly more common during the first 2 years of life and during the teenage years.Jan 12, 2022

Why do kids get leukemia?

The exact cause of most childhood leukemias is not known. Most children with leukemia do not have any known risk factors. Still, scientists have learned that certain changes in the DNA inside normal bone marrow cells can cause them to grow out of control and become leukemia cells.Feb 12, 2019

How I found out my child has leukemia?

Bone marrow aspiration and biopsy: This test is usually needed to tell for sure if your child has leukemia. A doctor uses thin, hollow needles to remove small amounts of bone marrow, usually from the hip bone. The area around the bone is numbed, and the child may be given a drug to make them sleep during the test.Feb 12, 2019

Can leukemia be cured if caught early?

Leukemia is the cancer of the blood-forming tissues that includes bone marrow and lymphatic system. Adults and children are equally affected by Leukemia, which is seen as production of abnormal white blood cells by the bone marrow.Mar 7, 2016

Can leukemia be cured without chemo?

As with other types of cancer, there's currently no cure for leukemia. People with leukemia sometimes experience remission, a state after diagnosis and treatment in which the cancer is no longer detected in the body.May 3, 2021

How long is chemo for child leukemia?

The entire length of treatment is typically about 2 to 3 years, with the most intense treatment in the first few months. Children with ALL are typically classified by risk group to make sure that the correct types and doses of drugs are given. Treatment may be more or less intense, depending on the risk group.Feb 12, 2019

What gender is most affected by leukemia?

Gender: Men are more likely than woman to develop leukemia. Age: The risk of most leukemias increase with age. The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older.Feb 2, 2022

How long do childhood leukemia survivors live?

Conditional life expectancy was 48.5 years (95% UI, 47.6-49.6 years) for survivors who received a diagnosis during the 1970-1979 era, 53.7 years (95% UI, 52.6-54.7 years) for survivors who received a diagnosis during the 1980-1989 era, and 57.1 years (95% UI, 55.9-58.1 years) for survivors who received a diagnosis ...Jan 2, 2020

What are the side effects of childhood leukemia?

Children treated for leukemia or lymphoma may be at risk for fatigue, growth delays, thyroid dysfunction, hearing loss and the development of a secondary cancer. Children may also become infertile.

What is the best treatment for leukemia?

If the leukemia remains in remission after induction and consolidation, maintenance therapy can begin. Most treatment plans use daily 6-mercaptopurine (6-MP) and weekly methotrexate, given as pills, often along with vincristine, which is given into a vein (IV), and a steroid (prednisone or dexamethasone). These latter 2 drugs are given ...

How long does it take to get rid of lymphocytic leukemia?

The main treatment for children with acute lymphocytic (lymphoblastic) leukemia (ALL) is chemotherapy, which is usually given in 3 main phases: The entire length of treatment is typically about 2 to 3 years, with the most intense treatment in the first few months. Children with ALL are typically classified by risk group to make sure ...

What is the goal of induction chemotherapy?

Induction. The goal of induction chemotherapy is to achieve a remission. This means that leukemia cells are no longer found in bone marrow samples, the normal marrow cells return, and the blood counts become normal. (A remission is not necessarily a cure.) More than 95% of children with ALL enter remission after 1 month of induction treatment.

What is intrathecal chemo?

Intrathecal chemotherapy: All children also get chemo into the cerebrospinal fluid (CSF) to kill any leukemia cells that might have spread to the brain and spinal cord. This treatment, known as intrathecal chemotherapy, is given through a lumbar puncture (spinal tap).

How often is methotrexate given?

It is usually given twice (or more if the leukemia is high risk or leukemia cells have been found in the CSF) during the first month and several times during the next 1 or 2 months. It is then repeated less often during the rest of treatment. Usually, methotrexate is the drug used for intrathecal chemo.

Can a child get chemo after relapse?

If the ALL recurs (comes back) during or after treatment, the child will most likely be treated again with chemotherapy. Much of the treatment strategy depends on how soon the leukemia returns after the first treatment. If the relapse occurs after a long time, the same drugs might still be effective, so the same or similar treatment may be used to try to get the leukemia into a second remission.

How long does the consolidation phase of chemo last?

Consolidation (intensification) The next, and usually more intense, consolidation phase of chemo starts once the leukemia is in remission and typically lasts for several months. This phase further reduces the number of leukemia cells still in the body.

What is the treatment for childhood leukemia?

Other treatments might also be used in special circumstances. Surgery for Childhood Leukemia. Radiation Therapy for Childhood Leukemia.

What to do if your child has leukemia?

It’s important to weigh the benefits of each treatment option against the possible risks and side effects.

What to do after leukemia diagnosis?

Making treatment decisions. After leukemia is diagnosed and tests have been done to determine its type, your child’s cancer care team will discuss the treatment options with you. It’s important to discuss your child’s treatment options as well as their possible side effects with the treatment team to help make the decision that’s ...

What to do if you don't understand cancer?

If there is anything you don’t understand, ask to have it explained. If time allows, getting a second opinion from another doctor experienced with your child’s type of cancer is often a good idea. This can give you more information and help you feel more confident about the treatment plan you choose.

What is clinical trial?

Clinical trials are one way to get state-of-the art cancer treatment. Sometimes they may be the only way to get access to newer treatments (although there is no guarantee that newer treatments will be better). They are also the best way for doctors to learn better methods to treat these cancers.

What is complementary medicine?

Complementary methods refer to treatments that are used along with your regular medical care. Alternative treatments are used instead of standard medical treatment.

What are the services that help with cancer?

These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. For children and teens with cancer and their families, other specialists can be an important part of care as well.

What happens when you have leukemia?

When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.

What is the term for cancer of the blood cells?

Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job: White blood cells help your body fight infection.

What are the functions of blood cells?

Each type of cell has a different job: White blood cells help your body fight infection. Red blood cells deliver oxygen from your lungs to your tissues and organs. Platelets help form clots to stop bleeding. When you have leukemia, your bone marrow makes large numbers of abnormal cells.

Is CML rare in children?

Chronic myeloid leukemia (CML), in which the bone marrow makes abnormal granulocytes (a type of white blood cell). It is very rare in children. There are some other rare types of leukemia in children, including juvenile myelomonocytic leukemia (JMML).

Can leukemia be treated?

The treatments for leukemia depend on which type it is, how severe the leukemia is, the child's age, and other factors. Possible treatments might include. Treatment for childhood leukemia is often successful. But the treatments can cause complications right away or later in life.

What is CBC test?

Blood tests, such as a complete blood count (CBC) Bone marrow tests. There are two main types - bone marrow aspiration and bone marrow biopsy. Both tests involve removing a sample of bone marrow and bone. The samples are sent to a lab for testing. Genetic tests to look for gene and chromosome changes.

Is leukemia fast growing?

There are different types of leukemia. Some types are acute (fast growing). They usually get worse quickly if they are not treated. Most childhood leukemias are acute: Acute lymphocytic leukemia (ALL), which is the most common type of leukemia in children and the most common cancer in children. In ALL, the bone marrow makes too many lymphocytes, ...

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Induction

  • The goal of induction chemotherapy is to achieve a remission. This means that leukemia cells are no longer found in bone marrow samples, the normal marrow cells return, and the blood counts become normal. (A remission is not necessarily a cure.) More than 95% of children with ALL enter remission after 1 month of induction treatment. This first month is intense and requires prolong…
See more on cancer.org

Consolidation

  • The next, and usually more intense, consolidation phase of chemo starts once the leukemia is in remission and typically lasts for several months. This phase further reduces the number of leukemia cells still in the body. Several chemo drugs are combined to help prevent the remaining leukemia cells from developing resistance. Intrathecal chemo (as described above) is continue…
See more on cancer.org

Maintenance

  • If the leukemia remains in remission after induction and consolidation, maintenance therapy can begin. Most treatment plans use daily 6-mercaptopurine (6-MP) and weekly methotrexate, given as pills, often along with vincristine, which is given into a vein (IV), and a steroid (prednisone or dexamethasone). These latter 2 drugs are given for brief periods every 4 to 8 weeks. Other drug…
See more on cancer.org

Treatment of Residual Disease

  • The treatment plans may change if the leukemia doesn’t go into remission during induction or consolidation. The doctor will probably check the child’s bone marrow soon after treatment starts to see if the leukemia is going away. If not, treatment might need to be more intense or prolonged. If standard lab tests show the leukemia seems to have gone away, the doctor may use more sen…
See more on cancer.org

Treatment of Recurrent All

  • If the ALL recurs (comes back) during or after treatment, the child will most likely be treated again with chemotherapy. Much of the treatment strategy depends on how soon the leukemia returns after the first treatment. If the relapse occurs after a long time, the same drugs might still be effective, so the same or similar treatment may be used to try to get the leukemia into a second …
See more on cancer.org

Philadelphia Chromosome-Type All

  • For children with certain types of ALL, such as those with the Philadelphia chromosome, standard chemotherapy for ALL (as outlined above) might not be as effective. A stem cell transplantmay be advised if induction treatment puts the leukemia in remission and a suitable stem cell donor is available. Newer, targeted drugssuch as imatinib (Gleevec) and dasatinib (Sprycel) are designe…
See more on cancer.org

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