What is the primary target when using medication to lower lipids?
Summary: ATP III recommendations state, on triglycerides and HDL-cholesterol as targets to reduce cardiovascular risk: (1) that lowering LDL-cholesterol levels is the primary target of therapy, (2) a secondary target is to achieve a triglyceride level < 150 mg/dL and (3) clinical trial data are considered to be ...
What is the primary treatment for hyperlipidemia?
The basis of treating hyperlipidemia remains diet, physical exercise and weight reduction. Olive oil and nuts have been shown to be beneficial. Statins remain first line drug treatment. Further treatment options are ezetimibe, bile acid sequestrants, fibrates and fish oil.
What is the main treatment option for primary or secondary hyperlipidemia?
Statins have the most convincing data for primary prevention, especially for higher risk patients. Therefore, risk stratification is essential. Statin therapy is also recommended for secondary prevention in all patients with known cardiovascular disease or the risk equivalent.Sep 1, 2011
What is the goal of cholesterol management?
LDL Goal: less than 100 mg/dl with a therapeutic option of treating to under 70 mg/dL. For very high-risk patients whose LDL levels are already below 100 mg/dL, there is also an option to use drug therapy to reach the less than 70 mg/dL goal.May 24, 2019
What is primary hyperlipidemia?
The term “primary hyperlipidemias” include a heterogeneous set of monogenic and polygenic entities characterized by a family aggregation, severe forms of hypercholesterolemia and/or hypertriglyceridemia, appearance early on life and a high risk of cardiovascular events and/or recurrent pancreatitis (1-3).Dec 9, 2021
When should hyperlipidemia be treated?
Dietary therapy should be initiated in patients who have borderline-high LDL cholesterol levels (130 to 159 mg per dL [3.35 to 4.10 mmol per L]) and two or more risk factors for coronary heart disease and in patients who have LDL levels of 160 mg per dL (4.15 mmol per L) or greater.May 1, 1998
What class of drugs is used in the treatment of hyperlipidemia?
HMG-CoA Reductase Inhibitors (Statins) Statins are the most commonly prescribed lipid-lowering agents in the United States. They are generally effective, are supported by favorable outcome studies and have relatively few adverse effects.Jun 1, 2000
Which drug indicated for dyslipidemia?
The most commonly used options for the pharmacologic treatment of dyslipidemia are statins, resins, fibrate, niacin, and their combinations.Jan 21, 2018
What is the main cause of hyperlipidemia?
Hyperlipidemia is most commonly associated with high-fat diets, a sedentary lifestyle, obesity and diabetes. There are also genetic causes. Familial hypercholesterolemia, one form of hyperlipidemia, is the most common dominantly inherited genetic disorder in humans worldwide.
What are lipid goals?
Finally, those with 0-1 risk factor have a goal LDL cholesterol of <160 mg/dL. These goals are set to maximize reduction in both short-term and long-term risk....1. Therapeutic goals for LDL cholesterol.Risk LevelLDL-C GoalMultiple (2+) Risk Factors<130 mg/dL*0-1 Risk Factor<160 mg/dL1 more row•Dec 17, 2002
What is the treatment goals in the management of hyperlipidemia?
Hyperlipidemia should be treated with an LDL-C goal of less than 130 mg/dL for patients at low to moderate risk for CAD and less than 100 mg/dL for high-risk patients (strength of recommendation: B).
What is the target for LDL and HDL?
Men age 20 or older:Type of CholesterolHealthy LevelTotal Cholesterol125 to 200mg/dLNon-HDLLess than 130mg/dLLDLLess than 100mg/dLHDL40mg/dL or higherOct 2, 2020