Treatment FAQ

what is the most effective treatment for peyronie's disease

by Mr. Garrick Kub III Published 2 years ago Updated 2 years ago
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Surgery. Surgery has been shown to be the most effective treatment for Peyronie's disease to correct the curvature of the penis. However, it is usually only recommended in severe cases for patients who fail to respond to non-surgical therapy and have curvature for longer than 12 months.

Medication

In many cases, the best Peyronie’s disease treatment is surgery. There are primarily two different types of surgery, with Dr. Gelman advising the patient to undergo either a penile plication or penile graft surgery. Successful surgery will correct any noticeable signs of curvature, allowing for normal sexual intercourse.

Procedures

Jul 30, 2019 · There are several ways to treat Peyronie’s disease, but three common ones are: Surgery to correct the curvature and straighten the penis. Injections of collagenase Clostridium histolyticum (CCH) directly into the plaques. Traction therapy – stretching the penis with a device like the RestoreX, which is used 30-90 minutes every day.

Nutrition

Most tried and most effective treatments for Peyronie's disease based on the experiences of 28 diagnosed members of the Peyronie's disease research community

What treatment do you recomend for Peyronies disease?

Are there any ways to cure Peyronies disease?

How to cure Peyronie's naturally?

What can be done to help with Peyronie's disease?

See more

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What is the newest treatment for Peyronie's disease?

Eur J Rheumatol Inflamm.

How do you dissolve Peyronie's plaque?

Intralesional collagenase injections (Xiaflex) are currently the only FDA-approved treatment for Peyronie's disease. Collagenase is an enzyme that helps break down the substances that make up plaques. Breaking down the plaques reduces penile curving and improves erectile function.

Is there any hope for Peyronie's disease?

Peyronie's disease is the development of fibrous tissue in the penis that can cause curved and painful erections. Up to 13 percent of men may have the condition, yet that number could be much higher as most men don't talk about it. It's an extremely treatable condition, but you need to see a doctor.Aug 7, 2019

How do you get rid of Peyronie's disease without surgery?

Non-surgical treatments for PD include injectable drugs, penile traction, and shockwave therapy. All of them can help slow the progression of the condition, before it interferes.Mar 25, 2021

Can peyronies be reversed?

Treatment for Peyronie's disease. There's no cure for Peyronie's disease, but it's treatable and may go away on its own. Though it may be tempting to request medication right away, many doctors prefer the “watchful waiting” approach if your symptoms aren't severe.

What happens if Peyronie's disease is left untreated?

If left untreated, Peyronie's disease may cause fibrotic, nonexpansile thickening of relatively discrete areas of the corpora tunica, typically resulting in focal bend, pain or other functional or structural abnormalities of the erect penis. Many cases resolve without treatment.Aug 1, 1999

Does Viagra work for Peyronie's disease?

Medications prescribed for erectile dysfunction (Viagra, Levitra, Cialis) are sometimes beneficial for patients in the early stages of Peyronie's disease.

How to cure Peyronie's disease?

In many cases, the best Peyronie’s disease treatment is surgery. There are primarily two different types of surgery, with Dr. Gelman advising the patient to undergo either a penile plication ...

What is pentoxifylline used for?

Pentoxifylline is a medication that has been used for many years for the treatment of intermittent leg cramping (claudication). It has gained recent attention as a potentially effective Peyronie’s disease treatment. Trental is now at the Center for Reconstructive Urology what Vitamin E was 20 years ago at our Center.

Does Vitamin E help with peyronies?

For decades, Vitamin E has been commonly prescribed Peyronie’s disease treatment because it is inexpensive and can be an effective treatment for scarring (of the skin).

Is Verapamil a tablet?

Unlike the other treatments listed above, Verapamil is not a tablet or pill. Rather, it is Peyronie’s disease treatment that is applied as a topical cream, but also can be injected directly into the penis. Verapamil is a calcium inhibitor that is often used to treat hypertension. It is thought that the this medication may alter fibroblast function. Fibroblast cells are involved in wound healing after tissue injury. It is called “transdermal” as supposedly, the medication can travel through the skin into the plaque leading to a beneficial change. Certainly this medication is effective in increasing the income of those who promote and sell this drug. However, there is no clearly established proven efficacy for this medicaiton being a Peyronie’s Disease cure or effective treatment in the peer-reviewed published literature.

What is penis curvature?

Penile curvature is generally related to the development of a dense inelastic plaque within the penis. In order for creams, pills or other treatments to be effective, they need to change the affected tissue from a dense scar back to elastic, supple, and healthy tissue.

How does Potaba work?

This medication is composed of potassium p-aminobenzoate and is considered an antifibrotic medication, which means that Potaba is thought to prevent fibrosis (scarring) by increasing oxygen uptake at the tissue level. In order for the medication to be effective, patients are required to take large doses every day for months at a time. The recommended daily dose is 4 (0.5gram) tablets or 6 capsules, and the number of pills patients are asked to take discourages many from going with this Peyronie’s treatment. This medication was popular in the 1990s but is no longer in use.

Who makes Xiaflex?

The manufacturer was Auxillium (now owned by Endo Pharmaceuticals). Xiaflex is a medication that is injected into the plaque inside the penis. Prior to Xiaflex injection, a different medication is injected into the penis to produce an erection to identify the area of maximum curvature, and that is marked.

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Diagnosis

Clinical Trials

Coping and Support

Preparing For Your Appointment

Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Initially the condition is monitored and if there is no improvement, then it is treated by medication or surgery based on the severity.
Medication

Hemorrheologic agents: Improve blood flow and reduce the amount of scar tissue.

Pentoxifylline


Enzymes: Used to improve the curvature and problems associated with the condition.

Collagenase clostridium histolyticum


Anti hypertensive drugs: Used to treat high blood pressure.

Verapamil


Proteins: It disrupts the production of scar tissues and breaks it down.

Interferon

Procedures

Plication: Suturing (plicating) the unaffected side results in a straightening of the penis.

Incision and grafting: Cuts are made in scar tissue to stretch out the sheath and allow the penis to straighten.

Iontophoresis: Verapamil and a steroid are administered noninvasively to improve the penile curvature and erectile function.

Penile implant surgery: Used to replace the spongy tissue that fills with blood during an erection.

Nutrition

Foods to eat:

  • NA

Foods to avoid:

  • NA

Specialist to consult

Primary care physician
Specializes in the acute and chronic illnesses and provides preventive care and health.

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