Treatment FAQ

what is the most common treatment for non-hodjkin's lymphoma?

by Ms. Evelyn Krajcik Published 2 years ago Updated 2 years ago

Chemotherapy is a widely used treatment for non-Hodgkin lymphoma that involves using medicine to kill cancer cells. It may be used on its own, combined with biological therapy, or combined with radiotherapy. The medication can be given in a number of different ways, depending on the stage of your cancer.

Medication

Depending on the type and stage (extent) of the lymphoma and other factors, treatment options for people with NHL might include: Chemotherapy for Non-Hodgkin Lymphoma. Immunotherapy for Non-Hodgkin Lymphoma. Targeted Therapy Drugs for Non-Hodgkin Lymphoma. Radiation Therapy for Non-Hodgkin Lymphoma.

Procedures

Follicular lymphoma. Follicular lymphoma is the most common type of indolent non-Hodgkin lymphoma. It is a very slow-growing type of non-Hodgkin lymphoma that begins in B lymphocytes. It affects the lymph nodes and may spread to the bone marrow or spleen.

Therapy

Here are some of the drugs more commonly used to treat lymphoma (divided into groups based on how they work): Often drugs from different groups are combined. One of the most common combinations is called CHOP. This includes the drugs c yclophosphamide, doxorubicin (also known as h ydroxydaunorubicin), vincristine ( O ncovin) and p rednisone.

Self-care

Nutrition

What is the best treatment for non Hodgkin lymphoma?

What is the most common non Hodgkin lymphoma?

What drugs are used to treat lymphoma?

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What is the newest treatment for non-Hodgkin's lymphoma?

Brentuximab vedotin (Adcetris) is made up of an antibody to CD30 that is attached to a cell poison. It has been shown to help treat patients with anaplastic large cell lymphoma (ALCL), and is now being studied for use against other types of lymphoma.

How long does it take to cure non-Hodgkin's lymphoma?

A short course of treatment usually takes about 6 to 12 weeks. Or you might have a longer course of chemotherapy and a targeted drug, without radiotherapy. Whether you have radiotherapy depends on factors such as where the lymphoma is in the body and how fit you are.

What are the treatment options for adults with non-Hodgkin lymphoma?

Depending on the type and stage (extent) of the lymphoma and other factors, treatment options for people with NHL might include:Chemotherapy for Non-Hodgkin Lymphoma.Immunotherapy for Non-Hodgkin Lymphoma.Targeted Drug Therapy for Non-Hodgkin Lymphoma.Radiation Therapy for Non-Hodgkin Lymphoma.More items...

Can you be cured of non Hodgkins lymphoma?

Many people with a high-grade non-Hodgkin's lymphoma will be cured. Therefore, the usual aim of treatment for high-grade non-Hodgkin's lymphoma is to cure it. A cure is most likely in cases which are at an early stage. However, there is still a good chance of a cure even with those in more advanced stages.

What is the life expectancy of someone with non-Hodgkin's lymphoma?

The overall 5-year relative survival rate for people with NHL is 73%. But it's important to keep in mind that survival rates can vary widely for different types and stages of lymphoma....Follicular lymphoma.SEER Stage5-Year Relative Survival RateAll SEER stages combined90%3 more rows•Mar 2, 2022

Can you live a long life after non-Hodgkin lymphoma?

Takeaway. The outlook for people with non-Hodgkin's lymphoma isn't generally as good as that of Hodgkin's lymphoma, but it still has a better outlook than many other cancers. More than 70 percent of people live longer than 5 years after their diagnosis.

What is the first line of treatment for non-Hodgkin's lymphoma?

Chemo is the main treatment for most people with non-Hodgkin lymphoma (NHL). Depending on the type1 and the stage2 of the lymphoma, chemo may be used alone or combined with other treatments, such as immunotherapy drugs or radiation therapy.

What is the best chemo for non-Hodgkin's lymphoma?

Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), plus the monoclonal antibody rituximab (Rituxan). This regimen, known as R-CHOP, is most often given in cycles 3 weeks apart.

How many rounds of chemo do you need for lymphoma?

Treatment for many patients is chemotherapy (usually 2 to 4 cycles of the ABVD regimen), followed by radiation to the initial site of the disease (involved site radiation therapy, or ISRT). Another option is chemotherapy alone (usually for 3 to 6 cycles) in selected patients.

Is non-Hodgkin's lymphoma a death sentence?

What is the survival rate for non-Hodgkin lymphoma? According to the American Cancer Society, about 71 percent of people of all races with non-Hodgkin lymphoma are still alive five years after diagnosis. Children tend to fare better, with 87 percent living for at least five years after diagnosis.

What is the main cause of non-Hodgkin's lymphoma?

Non-Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called lymphocytes, although the exact reason why this happens isn't known. DNA gives cells a basic set of instructions, such as when to grow and reproduce.

Is non-Hodgkin's lymphoma a terminal illness?

Yes, NHL is a very treatable disease and curable in many cases, particularly with aggressive NHL. Before treatment begins, it is necessary to know how far the cancer has advanced. This is called the stage of the disease.

What tests can be done to detect lymphoma?

Imaging tests. Your doctor may recommend imaging tests to look for signs of lymphoma cells elsewhere in your body. Tests may include CT, MRI and positron emission tomography (PET). Lymph node test. Your doctor may recommend a lymph node biopsy procedure to remove all or part of a lymph node for laboratory testing.

What tests can be done to check for swollen lymph nodes?

Physical exam. Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as for a swollen spleen or liver. Blood and urine tests. Blood and urine tests may help rule out an infection or other disease. Imaging tests.

What is car T cell therapy?

A specialized treatment called chimeric antigen receptor (CAR)- T cell therapy takes your body's germ-fighting T cells, engineers them to fight cancer and infuses them back into your body. CAR -T cell therapy might be an option for certain types of B-cell non-Hodgkin's lymphoma that haven't responded to other treatments.

What is the best way to kill cancer cells?

Radiation therapy. Radiation therapy uses high-powered energy beams, such as X-rays and protons, to kill cancer cells. During radiation therapy, you lie on a table and a large machine moves around you, directing the energy beams to specific points on your body.

How does immunotherapy work?

Immunotherapy uses your immune system to fight cancer. Your body's disease-fighting immune system may not attack your cancer because the cancer cells produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

Can radiation kill lymphoma?

For certain types of non-Hodgkin's lymphoma, radiation therapy may be the only treatment you need, particularly if your lymphoma is slow growing and located in just one or two spots. More commonly, radiation is used after chemotherapy to kill any lymphoma cells that might remain.

Can immunotherapy be used for non-Hodgkin's lymphoma?

Immunotherapy drugs may be an option for certain types of non-Hodgkin's lymphoma if other treatments haven't helped. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form.

What is the most common type of non-Hodgkin lymphoma?

Follicular lymphoma. Follicular lymphoma is the most common type of indolent non-Hodgkin lymphoma. It is a very slow-growing type of non-Hodgkin lymphoma that begins in B lymphocytes. It affects the lymph nodes and may spread to the bone marrow or spleen. Most patients with follicular lymphoma are age 50 years and older when they are diagnosed. Follicular lymphoma may go away without treatment. The patient is closely watched for signs or symptoms that the disease has come back. Treatment is needed if signs or symptoms occur after the cancer disappeared or after initial cancer treatment. Sometimes follicular lymphoma can become a more aggressive type of lymphoma, such as diffuse large B-cell lymphoma.

What is non-Hodgkin lymphoma?

Non-Hodgkin lymphoma is a disease in which malignant (cancer) cells form in the lymph system. Non-Hodgkin lymphoma is a type of cancer that forms in the lymph system. The lymph system is part of the immune system. It helps protect the body from infection and disease. The lymph system is made up of the following:

What is the name of the B cell lymphoma that grows and spreads quickly?

Burkitt lymphoma. Burkitt lymphoma is a type of B-cell non-Hodgkin lymphoma that grows and spreads very quickly. It may affect the jaw, bones of the face, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt lymphoma ( endemic, sporadic, and immunodeficiency related).

What is intravascular large B cell lymphoma?

Intravascular large B-cell lymphoma. This type of non-Hodgkin lymphoma affects blood vessels, especially the small blood vessels in the brain, kidney, lung, and skin. Signs and symptoms of intravascular large B-cell lymphoma are caused by blocked blood vessels. It is also called intravascular lymphomatosis.

What are the symptoms of diffuse large B cell lymphoma?

It grows quickly in the lymph nodes and often the spleen, liver, bone marrow, or other organs are also affected. Signs and symptoms of diffuse large B-cell lymphoma may include fever, drenching night sweats, and weight loss. These are also called B symptoms.#N#Primary mediastinal large B-cell lymphoma. This type of non-Hodgkin lymphoma is a type of diffuse large B-cell lymphoma. It is marked by the overgrowth of fibrous (scar-like) lymph tissue. A tumor most often forms behind the breastbone. It may press on the airways and cause coughing and trouble breathing. Most patients with primary mediastinal large B-cell lymphoma are women who are age 30 to 40 years.

Where does lymph enter the body?

The lymph enters the blood through a large vein near the heart. Lymph tissue is also found in other parts of the body such as the lining of the digestive tract, bronchus, and skin. Cancer can spread to the liver and lungs. There are two general types of lymphomas: Hodgkin lymphoma and non-Hodgkin lymphoma.

Where does mantle cell lymphoma spread?

It begins in the lymph nodes and spreads to the spleen, bone marrow, blood, and sometimes the esophagus, stomach, and intestines.

What is the treatment for lymphoma?

Chemotherapy (chemo) is the use of anti-cancer drugs that are usually injected into a vein (IV) or taken by mouth. These drugs enter the bloodstream and reach almost all areas of the body, making this treatment very useful for lymphoma.

What is the name of the drug that is given to lymphoma patients?

To treat lymphoma that might have reached these areas, chemo may also be given into the CSF. This is called intrathecal chemo. The chemo drugs most often used for intrathecal chemo are methotrexate and cytarabine.

How long does chemo last?

Each chemo cycle generally lasts for several weeks.

What happens when you kill lymphoma cells?

Killing the lymphoma cells releases their contents into the bloodstream. This can overwhelm the kidneys, which can’t get rid of all of these substances at once. This can lead to the build-up of certain minerals in the blood and even kidney failure. The excess minerals can lead to heart and nervous system problems.

What is the most common drug combination?

One of the most common combinations is called CHOP. This includes the drugs c yclophosphamide, doxorubicin (also known as h ydroxydaunorubicin), vincristine ( O ncovin) and p rednisone. Another common combination leaves out doxorubicin and is called CVP.

Can chemo be used for lymphoma?

Many chemo drugs are useful in treating lymphoma. Often, several drugs are combined. The number of drugs, their doses, and the length of treatment depend on the type and stage of the lymphoma. Here are some of the drugs more commonly used to treat lymphoma (divided into groups based on how they work):

Can chemo be delayed?

If serious side effects occur, the dose of chemo may be reduced or treatment may be delayed. There are often ways to lessen these side effects. For example, drugs can be given to prevent or reduce nausea and vomiting. Certain chemo drugs can have other possible side effects. For example:

What is the goal of non-Hodgkin lymphoma?

The goal of treatment is to eradicate the lymphoma while causing as little damage as possible to normal cells to minimize the side effects of treatment .

What tests are needed for lymphoma?

Depending on your specific symptoms, the type of the lymphoma, its site of origin, and the biopsy results, you will need some or all of the following tests: Blood tests. Bone marrow biopsy. Chest X-ray. Computed tomography (CT) scans of the neck, chest, abdomen, and pelvis.

What is the procedure to biopsy a lymph node?

To perform a lymph node biopsy a doctor will cut into the lymph node to remove a sample of tissue or remove the entire lymph node. If the biopsy shows non-Hodgkin lymphoma, further testing will be needed to determine the specific type as well as to determine the stage of disease.

Can you treat non-Hodgkin lymphoma alone?

The most common treatments for non-Hodgkin's lymphoma include: These treatments may be used in combination or alone, depending on the type, stage, and symptoms of the non-Hodgkin lymphoma.

Is there a way to prevent non-Hodgkin lymphoma?

Prevention of Non-Hodgkin Lymphoma. Because most causes of non-Hodgkin lymphoma are unknown, there are few ways known to prevent it. Researchers are looking into prevention of infections that have been associated with non-Hodgkin lymphoma, such as HHV-8, HIV, HTLV-1, and H. pylori.

Diagnosis

Treatment

Clinical Trials

Alternative Medicine

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
The choice of treatment is based on the type and stage of lymphoma, age and overall health of the patient. Slow growing lymphoma may not require any treatment, but a regular follow-up may be recommended.
Medication

Chemotherapy: To kill cancer cells; administered orally or intravenously.

Cyclophosphamide . Doxorubicin


Targeted therapy: To improve body’s immune system.

Rituximab

Procedures

Bone marrow transplantation: It is also known as stem cell transplant and the therapy involves introducing healthy bone marrow stem cells from a donor.

Therapy

Radiation therapy:High-powered energy beams like X-rays are used to kill cancerous cells and shrink tumors.

Self-care

Always talk to your provider before starting anything.

  • Learn about your condition.
  • Keep your family and friends informed of your condition.
  • Eat a healthy and nutritious diet.
  • Remain active.

Nutrition

Foods to eat:

  • Foods rich in carbohydrates like rice, bread and pasta
  • Foods rich in vitamins and minerals like fruits and vegetables
  • Milk and other dairy Foods

Foods to avoid:

  • Foods rich in saturated fats like butter, meat and cakes
  • Processed Foods like sausages and crisps

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Hematologist
Specializes in the study of the blood and blood disorders.

Coping and Support

Preparing For Your Appointment

  • Several non-Hodgkin's lymphoma treatments are available. Which treatment or combination of treatments is best for you will depend on the particulars of your lymphoma, such as the types of cells involved and whether your lymphoma is aggressive. Your doctor also considers your overall health and your preferences. If your lymphoma appears to be slow growing (indolent) and doesn'…
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