Treatment FAQ

what is the most common treatment for ductal carcinoma in situ

by Craig Moen Published 2 years ago Updated 1 year ago
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  • Breast-conserving surgery (BCS) In breast-conserving surgery (BCS), the surgeon removes the tumor and a small amount of normal breast tissue around it.
  • Mastectomy. Simple mastectomy (removal of the entire breast) may be needed if the area of DCIS is very large, if the breast has several separate areas of DCIS, or if ...
  • Hormone therapy after surgery. If the DCIS is hormone receptor-positive (estrogen or progesterone), treatment with tamoxifen (for any woman) or an aromatase inhibitor (for women past menopause) for 5 years ...

Lumpectomy with radiation after surgery: This is the most common treatment for DCIS. A lumpectomy is surgery that removes all of the DCIS along with a bit of the surrounding healthy breast tissue that borders the cancer growth. This is to make sure that all of the abnormal cancer cells have been removed.Aug 5, 2018

Is chemotherapy needed for ductal carcinoma?

Radiation therapy might be needed Detailed Answer: Thanks for asking on HealthcareMagic. DCIS (Ductal Carcinoma In Situ) is usually non-invasive and hence chemotherapy is not needed. But radiation therapy might be needed, especially because Comedo-type Necrosis was present and since lymph node involvement was present or suspected.

Why is DCIS not cancer?

DCIS is stage 0: It has not spread outside a breast duct (where virtually all breast cancer begins) into the surrounding breast tissue. For this reason, DCIS is often referred to as a precancer. If left untreated, some DCIS lesions go on to become invasive cancers, while others remain a harmless precancer and never leave the duct.

Do I need surgery for DCIS?

While DCIS isn’t considered life threatening, it does increase the risk of developing invasive breast cancer later in life. DCIS usually is treated with surgery to remove the cancer -- lumpectomy in most cases. After surgery, hormonal therapy may be recommended if the DCIS is hormone-receptor-positive (most are).

How serious is invasive ductal carcinoma?

Invasive ductal carcinoma describes the type of tumor in about 80 percent of people with breast cancer. The five-year survival rate is quite high -- almost 100 percent when the tumor is caught and treated early. Once the cancer has metastasized to distant organs like the bones or liver, the five-year survival rate drops by almost three fourths.

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What is the best treatment for ductal carcinoma in situ?

Radiation therapy Treatment of DCIS has a high likelihood of success, in most instances removing the tumor and preventing any recurrence. In most people, treatment options for DCIS include: Breast-conserving surgery (lumpectomy) and radiation therapy. Breast-removing surgery (mastectomy)

Do you need chemo for ductal carcinoma in situ?

Chemotherapy. Chemotherapy is not needed for DCIS since the disease is noninvasive. Hormonal (endocrine) therapy. Hormonal (endocrine) therapy may be appropriate for those whose ductal carcinoma in situ is hormone receptor positive.

How serious is ductal carcinoma in situ?

DCIS is non-invasive because it hasn't spread beyond the milk ducts into other healthy tissue. DCIS isn't life-threatening, but if you're diagnosed with DCIS, you have a higher-than-average risk of developing invasive breast cancer later in life.

What is the treatment for DCIS stage 0?

Surgery is the main treatment for DCIS. Most women are offered breast-conserving surgery. If there are several areas of DCIS in the breast, doctors may do a mastectomy to make sure that all of the cancer is removed.

Do I need a mastectomy for DCIS?

Most women with DCIS or breast cancer can choose to have breast-sparing surgery, usually followed by radiation therapy. Most women with DCIS or breast cancer can choose to have a mastectomy. You have small breasts and a large area of DCIS or cancer. You have DCIS or cancer in more than one part of your breast.

Can DCIS come back after lumpectomy?

A study found that radiation therapy given after DCIS is removed by lumpectomy reduces the risk that the DCIS will come back (recurrence).

What stage is ductal carcinoma in situ?

DCIS is also called intraductal carcinoma or stage 0 breast cancer. DCIS is a non-invasive or pre-invasive breast cancer. This means the cells that line the ducts have changed to cancer cells but they have not spread through the walls of the ducts into the nearby breast tissue.

What is the survival rate of ductal carcinoma in situ?

Although DCIS doesn't pose any risk, it can turn invasive and spread to other tissues at any time. The five-year survival rate of ductal carcinoma in situ (DCIS), also known as stage 0 breast cancer, is over 98 percent.

How quickly does DCIS spread?

Grade 1 DCIS is almost always ER and PR positive and is a very slow growing form of cancer. It can take years, even decades, to see progression of the disease. In some cases, it may take such a long time to spread beyond the breast duct that it is not an event that will happen during a person's lifetime.

Should I get a double mastectomy for DCIS?

“The findings suggest that patients and their doctors should focus on risk factors and appropriate therapy for the diseased breast, not the opposite breast, and that ipsilateral DCIS should not prompt a bilateral mastectomy.”

How long is treatment for ductal carcinoma?

How long does it take to recover from invasive ductal carcinoma treatment? People who undergo surgery for invasive ductal carcinoma usually recover in about two to four weeks. Healing may take longer if lymph nodes are removed or if you choose to undergo breast reconstruction.

Can DCIS come back after mastectomy?

Recurrence is rare following mastectomy for DCIS. Nevertheless, there remains a need to follow patients for in-breast, nodal, or contralateral breast events, which can occur long after the index DCIS has been treated.

What is a Lumpectomy for DCIS?

Lumpectomy for DCIS is usually followed by whole breast radiation therapy to lower the risk of [ 6-13 ]: DCIS recurrence (a return of DCIS) in the treated breast. Invasive breast cancer in the treated breast.

How to treat DCIS?

Surgery is the first step to treat DCIS. It removes the abnormal tissue from the breast. Depending on how far the DCIS has spread within the milk ducts, surgery can be mastectomy or lumpectomy. If DCIS is spread throughout the ducts, affecting a large part of the breast, a total (simple) mastectomy will be done.

Why is DCIS called in situ?

It’s called “in situ” (which means “in place”) because the cells have not left the milk ducts to invade nearby breast tissue. DCIS is also called intraductal (within the milk ducts) carcinoma. You may hear the terms “pre-invasive” or “pre-cancerous” to describe DCIS. DCIS is treated to try to prevent the development of invasive breast cancer.

How do pathologists determine the hormone receptor status of a DCIS tumor?

A pathologist determines the hormone receptor status of the DCIS by testing the tissue removed during a biopsy. Hormone receptor-positive (estrogen receptor-positive/progesterone receptor-positive) DCIS tumors express hormone receptors. This means they have a lot of hormone receptors..

Can you have a sentinel node biopsy after a mastectomy?

Once a mastectomy has been done, a person can’t have a sentinel node biopsy. If it turns out there’s invasive breast cancer (along with DCIS) in the tissue removed during the mastectomy, a sentinel node biopsy will have already been done.

Can a lumpectomy be done with DCIS?

If there’s little spread of DCIS within the ducts, a choice can be made between mastectomy or lumpectomy. With lumpectomy, the surgeon removes only the abnormal tissue in the breast and a small rim of normal tissue around it. The rest of the breast is left intact.

Can you get DCIS without radiation?

Because DCIS might progress to invasive breast cancer, almost all cases of DCIS are treated. Surgery (with or without radiation therapy) is recommended to treat DCIS. After surgery and radiation therapy, some people take hormone therapy. Learn more about treatments for DCIS. Learn about the risk of invasive breast cancer after treatment for DCIS.

What is the procedure to remove breast tissue?

The following procedures are considered surgery: Incisional biopsy: Through an incision, or a cut in the skin, the doctor can remove a sample of breast tissue to examine it further. Excisional biopsy: This procedure cuts out the entire lump of tissue from the breast.

What is the procedure to get a spot on a mammogram?

Biopsy: If a spot or a shadow is found on the mammogram, the doctor will recommend a biopsy. Core needle biopsy: With this procedure, the doctor inserts a large needle into the breast to get a big sample of the breast tissue that looked abnormal on the mammogram.

What is lumpectomy surgery?

A lumpectomy is surgery that removes all of the DCIS along with a bit of the surrounding healthy breast tissue that borders the cancer growth. This is to make sure that all of the abnormal cancer cells have been removed. With a lumpectomy, the surgeon will leave the majority of the breast intact.

How many DCIS cases are there in 2018?

The American Cancer Society expects that 63,960 new cases of DCIS will be found in 2018. Today more and more women are aware of the importance of early detection and are getting mammograms each year. Because of this, the number of cases of DCIS has increased.

What is a DCIS?

Ductal carcinoma in situ (DCIS) is a type of breast cancer. This is also called non-invasive or pre-invasive breast cancer. The cancer cells are found along the sides of the milk duct within the breast. Milk ducts are within each breast and are the tubes that let milk travel from the lobes (made up of lobules) to the nipple openings ...

What is the first step in diagnosing DCIS?

The following tests or procedures are usually used to diagnose DCIS: Breast examination: A routine breast exam is usually part of a regular physical. It is the first step in detecting breast cancer.

Is DCIS stage 0?

The lower the stage number, the better chance for successful treatment of the disease and for the best results. Although DCIS is always considered Stage 0, the tumor can be any size and may be found within several milk ducts inside the breast. With proper treatment, the prognosis is excellent.

How is DCIS diagnosed?

If a doctor sees the calcifications on your mammogram, he or she will recommend more tests, which could include a breast biopsy. During the biopsy, a doctor or other health care provider takes samples of cells or tissues from your body. The cells are examined by a pathologist — a doctor who checks for signs of disease in body tissues.

What is the treatment for DCIS?

Lumpectomy with radiation. The standard treatment is breast-preserving surgery (a lumpectomy) with radiation therapy, which results in successful outcomes for most patients. Cancers can be larger than expected, so about 20% of the time, patients need a re-excision lumpectomy — another surgery — to remove all of the cancer.

What should I expect after a DCIS diagnosis?

The outlook after DCIS diagnosis, Sun says, is encouraging. “With continued, rigorous monitoring, the prognosis for DCIS is excellent,” she explains. “Your doctor will recommend a regular screening schedule to guard against recurrence in the original breast, and to monitor the other breast for any signs of malignancy.

What Are Some Advantages Of Receiving Treatment For Dcis At Msk

At MSK, we have a very thoughtful approach to personalizing treatment for each person with DCIS. The doctors and patients make treatment decisions as a team.

Current Controversies In The Treatment Of Ductal Carcinoma In Situ Of The Breast

Giorgia Garganese1*, Simona Maria Fragomeni1*, Sonia Bove1, Maria Teresa Evangelista1, Ida Paris2, Danilo Di Giorgio1, Daniela Andreina Terribile1, Riccardo Masetti1

How Common Is Ductal Carcinoma In Situ

The American Cancer Society expects that 63,960 new cases of DCIS will be found in 2018. Today more and more women are aware of the importance of early detection and are getting mammograms each year. Because of this, the number of cases of DCIS has increased.

Overtreatment Of Ductal Carcinoma In Situ

9 out of ten ladies have no idea that some breast cancers by no means trigger issues or have turn into identified in the midst of their lives. This can be a downside that ductal carcinoma in situ has delivered to the fore.

How Is Dcis Treated

The options for treating DCIS are: lumpectomy, lumpectomy and radiation, a combination of those with tamoxifen, or mastectomy. You dont have to rush into any one treatment because your doctor or your friend or anyone else says you should. Its your breast, and your life. Take the time to decide whats best for you.

How Likely Is Dcis To Come Back

The chance of the DCIS coming back depends on various factors. But after mastectomy DCIS almost never comes back. In women who have just the area of DCIS removed the chance of it coming back is a bit higher. But it depends on the grade and type of DCIS.

Some Cases Of Dcis Will Progress Towards Invasive Breast Cancer If Left Untreated

There is a general consensus that DCIS may represent a transitional stage between the normal breast tissue and invasive breast carcinoma.

What is the best treatment for DCIS?

Doctors recommend this type of treatment for DCIS that is hormone-receptor-positive -- which means it responds to the hormone estrogen.

How to treat DCIS?

Surgery is the most common way that doctors treat DCIS. Most often, it’s done with a procedure called a lumpectomy. A surgeon removes only the affected area of the breast while leaving healthy tissue. Doctors also call this breast-conserving surgery. Sometimes, a doctor might suggest removing the whole breast.

Why is breast cancer called DCIS?

Doctors often call this type of breast cancer ductal carcinoma in situ (DCIS). It gets this name because the cancer is only in the breast ducts that carry milk.

Why do doctors recommend mastectomy?

This type of surgery is a mastectomy. Reasons why a doctor might suggest you have a mastectomy instead of a lumpectomy for DCIS include: The cancer covers a large area of the breast. The cancer is in more than one place.

What to do after a lumpectomy?

After a lumpectomy or mastectomy, some women may choose to have surgery to reconstruct their breast. The decision to have breast reconstruction is a personal one.

How long does radiation last for DCIS?

Radiation of the whole breast is the most common treatment. A machine delivers the radiation, often 5 days a week for several weeks . It might be an option to get radiation for only part of the breast. It’s not clear if this works as well as whole breast radiation.

Can chemo kill cancer cells?

No, most likely not. Chemotherapy uses drugs given throughout the body to kill fast-growing cells, including cancer. Because DCIS is only in the breast ducts, doctors don’t usually recommend chemotherapy to treat it.

Abstract

Standard options for the treatment of ductal carcinoma in situ (DCIS) include breast-conserving surgery (BCS) alone; BCS with radiotherapy or endocrine therapy, or both; and mastectomy. Survival is excellent with all options, but rates of local recurrence (LR) vary, as do quality-of-life measures.

INTRODUCTION

Ductal carcinoma in situ (DCIS) is a non-invasive malignancy comprising approximately 20% of all newly diagnosed breast cancers [ 1 ]. Distinguished by a malignant proliferation of ductal epithelial cells that are confined to the milk ducts, this ‘stage 0’ entity has been increasingly detected with the widespread adoption of screening mammography.

STANDARD TREATMENT OPTIONS

The fundamental goals of treating DCIS are to eradicate disease in the breast and prevent future development of invasive recurrence. This may be accomplished with mastectomy or BCS with or without adjuvant irradiation, and/or endocrine therapy.

BREAST-CONSERVATION: RISK FACTORS FOR LOCOREGIONAL RECURRENCE

While early trials provided a foundation for understanding the risk of LR after treatment of DCIS, modern data―largely examining patients who underwent BCS―suggest a substantial influence of several clinicopathologic features on risk of LR ( Table 2 ).

MASTECTOMY: RISK FACTORS FOR LOCOREGIONAL RECURRENCE

While the aforementioned factors are known to confer higher risk of LR after BCS, widely variable results have been reported on their association with locoregional recurrence after mastectomy, with past studies being limited by retrospective nature and small populations [ 36 – 39 ].

RISK ESTIMATION

A key aspect of decision making for many patients is an understanding of their individual risk of LR.

PRESENT RELEVANCE AND CONTROVERSIES

As a non-invasive entity with numerous treatment options, the optimal course of action for a patient with DCIS remains a subject of controversy, with concerns regarding both overtreatment and undertreatment.

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