What is the stereochemical outcome of (R) 1-bromo-4-methylhexane with sodium cyanide?
The stereochemical outcome is inversion at the carbon bearing the leaving group. A carbocation intermediate is formed. Nice work! You just studied 15 terms! Now up your study game with Learn mode. What is the major product formed upon treatment of (R) 1-bromo-4-methylhexane with sodium cyanide?
What solvents are used in SN1 reactions?
Aprotic solvents are good choices for SN1 reactions. The stereochemical outcome is inversion at the carbon bearing the leaving group. A carbocation intermediate is formed. The reaction of tert-butyl bromide, (CH3)3CBr, with methanol in an inert solvent proceeds by an SN1 mechanism to give tert-butyl methyl ether, (CH3)3COCH3.
What are the solvents used in a carbocation reaction?
A carbocation intermediate is formed. The mechanism has only one step. Polar, protic solvents are good choices for SN1 reactions. The stereochemical outcome is racemization at the carbon bearing the leaving group.
What do bromine radicals add to an alkene?
a. Bromine radicals add to the least substituted end of a carbon-carbon double bond of an alkene. b. The major anti-Markovnikov product obtained upon addition of HBr to alkenes in the presence of a peroxide is formed in a radical termination step.
Question
What is the major product formed upon treatment of (R)-1-bromo-4-methylhexane with sodium cyanide
SN2 S N 2 Reaction of Primary Alkyl Halides
Primary alkyl halides are very reactive towards substitution reaction. Primary alkyl halides will react with nucleophiles via the SN2 mechanism. If the SN2 reaction occurs at a chiral carbon, then inversion of configuration will result.