Treatment FAQ

what is the first line treatment for constipation

by Prof. Titus Powlowski Published 2 years ago Updated 2 years ago
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What is the best cure for constipation?

Bulk Laxatives Fiber Ispaghula (Psyllium) Methylcellulose Calcium Polycarbophil

How to make yourself poop immediately and relieve constipation?

Feb 20, 2022 · First-line treatment is fiber supplementation, increased water intake, gentle exercise, and occasional laxative use as required. Hemorrhoidal suppositories and sitz baths may offer symptomatic...

What is immediate relief of constipation?

Apr 16, 2021 · Nonpharmacologic treatment is the first-line management in constipation. This approach relies on educating patients about diet, fiber and fluid intake, physical activity, and toilet training. Low intake of fiber leads to greater probability of constipation . Dietary fibers are carbohydrate polymers and are digested in small extant in the colon.

What to do when medication makes you constipated?

Your child’s doctor may recommend giving your child an enema or laxative to help treat his or her constipation. Most laxatives are over-the-counter medicines taken by mouth until your child’s bowel movements are normal. Your child’s doctor may recommend stopping the laxative once your child has better eating and bowel habits.

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What is the most effective medication for constipation?

While all the new prescription products provide more treatment options, Wald says, most people don't need them. Instead, over-the-counter drugs such as polyethylene glycol (Miralax and generic), bisacodyl (Dulcolax laxative tablets and generic), or senna (Ex-Lax, Senokot, and generic) are a far better choice.Sep 26, 2021

What is the second line treatment for constipation?

Subsequent treatments if fiber is not successful or tolerated would include saline osmotic laxatives, lactulose, or stimulants like senna or bisacodyl. Recent data demonstrate polyethylene glycol laxative to be safe and effective as an initial or second-line agent for chronic constipation.

What is used in the treatment of constipation?

Lubiprostone (Amitiza) helps increase fluid secretion in the intestines, which helps pass stool through the intestines. Lubiprostone is used to treat: chronic constipation.

How is Dulcolax taken?

Swallow the tablet whole with a full glass of water. Dulcolax taken by mouth should produce a bowel movement within 6 to 12 hours. Dulcolax used in the rectum can produce much faster results. You should have a bowel movement within 15 to 60 minutes after using a rectal suppository.

What is the difference between amitiza and lubiprostone?

Irritable bowel syndrome is a group of different symptoms occurring together including abdominal pain and changes in bowel movements: diarrhea, constipation, or both....What are the main differences between Amitiza and Linzess?Main differences between Amitiza and LinzessWhat is the generic name?LubiprostoneLinaclotide7 more rows•Dec 28, 2018

What is Dulcolax 5mg used for?

Dulcolax Adult Tablets are used for the short-term relief of occasional constipation. Dulcolax Adult Tablets contain bisacodyl and belong to a group of medicines known as stimulant laxatives, which increase bowel movements.

What is enema procedure?

An enema involves inserting liquid or gas into the rectum, which is the lower part of the large intestine. The aim is to empty the bowels, allow for an examination, or administer medication. An enema can be effective in treating certain medical conditions, but regular enema use can cause serious health problems.

How to treat constipation?

If those changes don't help, your doctor may recommend medications or surgery.

What tests are used to diagnose constipation?

In addition to a general physical exam and a digital rectal exam, doctors use the following tests and procedures to diagnose chronic constipation and try to find the cause: Blood tests. Your doctor will look for a systemic condition such as low thyroid (hypothyroidism) or high calcium levels. An X-ray.

What is the best way to get stool to move through your colon?

Lubricants. Lubricants such as mineral oil enable stool to move through your colon more easily. Stool softeners. Stool softeners such as docusate sodium (Colace) and docusate calcium (Surfak) moisten the stool by drawing water from the intestines. Enemas and suppositories.

What are the causes of intestines to contract?

Stimulants including bisacodyl (Correctol, Dulcolax, others) and sennosides (Senokot, Ex-Lax, Perdiem) cause your intestines to contract. Osmotics. Osmotic laxatives help stool move through the colon by increasing secretion of fluid from the intestines and helping to stimulate bowel movements.

What is the effect of mu-opioid receptor antagonists on the intestine?

If constipation is caused by opioid pain medications, PAMORAs such as naloxegol (Movantik) and methylnaltrexone (Relistor) reverse the effect of opioids on the intestine to keep the bowel moving.

How to get rid of a swollen intestine?

Slowly begin to eat more fresh fruits and vegetables each day. Choose whole-grain breads and cereals.

How does biofeedback help you pass poop?

Biofeedback training involves working with a therapist who uses devices to help you learn to relax and tighten the muscles in your pelvis. Relaxing your pelvic floor muscles at the right time during defecation can help you pass stool more easily.

Where does Ispaghula come from?

Ispaghula comes from an Asian plant that has high water-binding capacity and is fermented in the colon. In an observational study with psyllium, the response to treatment was poor among patients with slow colonic transit, whereas 85% of patients without abnormal physiology improved or became symptom-free.

Why is castor oil used less?

Castor oil is used less commonly because of its side-effect profile and poor palatability. The effect of stimulant laxatives is dose dependent. Low doses prevent absorption of water and sodium, whereas high doses stimulate secretion of sodium, followed by water, into the colonic lumen.

Is bisacodyl a hydrolyzed substance?

Bisacodyl is hydrolyzed by intestinal enzymes and thus can act in the small and large intestines. Sodium picosulfate is hydrolyzed by colonic bacteria. Like anthraquinones, the action of sodium picosulfate is confined to the colon, and its activity is unpredictable because its activation depends on the bacterial flora.

Can stimulant laxatives cause constipation?

Stimulant laxatives vary widely in clinical effectiveness, and some patients with severe constipation are not helped by stimulant laxatives. Anthraquinones . Anthraquinones, such as cascara, senna, aloe, and frangula, are produced by a variety of plants.

Does calcium polycarbophil cause gas?

Calcium polycarbophil is a hydrophilic resin that is resistant to bacterial degradation and thus may be less likely to cause gas and bloating. In patients with IBS with features of constipation, calcium polycarbophil seems to improve overall symptoms and passage of stool, but not abdominal pain.11. Osmotic Agents.

Is sorbitol as effective as lactulose?

Sorbitol is as effective as lactulose and less expensive. A randomized, double-blind, crossover trial of lactulose (20 g/d) and sorbitol (21 g/d) showed no difference in regards frequency of bowel movements and patient preference. Patients using lactulose had more nausea compared with sorbitol.

Is peg better than lactulose?

The lowest dose of PEG produced the most normal stool consistency, whereas if PEG was used in higher doses it produced more liquid stools. Low-dose PEG has been shown in studies to be more effective than lactulose in the treatment of chronic constipation.

What is the best laxative for osmotic stools?

One of the commonly used osmotic laxatives is polyethylene glycol (PEG) [53]. PEG, in comparison with placebo, is significantly more effective in increasing the number of stools, lowering straining and alleviating the need for rescue laxatives.

What is the first line of medication for failure of nonpharmacological management?

In case of failure of nonpharmacological management, laxatives are the first line of medications [51]. Osmotic laxatives change osmotic gradient in the intestine. As a result, secretion of water and electrolytes in the intestine is higher, ultimately volume of stool is increased and consistency is reduced [6,14,52].

Is constipation a gastrointestinal disorder?

Constipation is one of the major gastrointestinal disorders diagnosed in clinical practice in Western countries. Almost 20% of population suffer from this disorder, which means constipation is a substantial utilization of healthcare. Pathophysiology of constipation is complex and multifactorial, where aspects like disturbance in colonic transit, ...

Does linaclotide cause diarrhea?

Linaclotide is successful in achieving spontaneous bowel movements and complete spontaneous bowel movements in constipated patients and patients with IBS-C [59]. The most common side effect of linaclotide is diarrhea which may occur during the first 4 weeks of therapy [60].

Is serotonin a target for multiple drugs?

Nevertheless the serotonin signaling pathway is a target for multiple drugs used in the constipation treatment. Other possible mechanisms of constipation involve influence of proto-oncogenes, overexpression of progesterone receptors, infectious agents, autoimmunity, and tyrosine kinase C [31]. 3.

Does psyllium help with colon transit?

Studies confirmed its effectiveness in increasing defecation frequency, weight and consistency of stool, and lower tenderness of pain in defecation, however Psyllium does not improve colon transit [43]. Insoluble fiber, e.g., bran, improves intestinal transit time [42].

Is probiotics as effective as placebo?

Nevertheless, in some trials, probiotics are still as efficient as placebo [ 5,10,20]. What is more, Yarullina et al. recently reported a lack of motor activity disturbance or dysbiosis in chronic constipation, challenging previous theories and compromising the efficacy of conventional probiotic treatment.

How to help a child with constipation?

Changing your child’s bowel movement patterns and behaviors may help treat constipation . Ask your potty-trained child to use the toilet after meals to build a routine. Use a reward system when your child uses the bathroom regularly. Take a break from potty training until the constipation stops.

How to treat rectal prolapse in a child?

Your child’s doctor may be able to treat rectal prolapse during an office visit by manually pushing the rectum back through the child’s anus. Helping a child prevent constipation is the best way to prevent rectal prolapse.

How to make your child's stools softer?

Changing what your child eats and drinks may make his or her stools softer and easier to pass. To help relieve symptoms, have him or her. Read about what your child should eat and drink to help relieve constipation. Have your child drink plenty of water and other liquids to help prevent constipation.

Can you give a child a laxative?

You should not give a child a laxative unless told to do so by a doctor. If your child is taking an over-the-counter or prescription medicine or supplement that can cause constipation, your child’s doctor may recommend stopping it, changing the dose, or switching to a different one.

What is the best medicine for constipation?

These drugs include methylnaltrexone (Relistor) and naloxegol (Movantik.) Surgery for constipation treatment. Sometimes constipation is caused by a structural problem in your colon or rectum. Your colon may be blocked or unusually narrow, or you may have a partial collapse or a bulge in the wall of your rectum.

How to get rid of constipation fast?

Gradually increase the amount of fiber in your diet until you're getting at least 20 to 35 grams of fiber daily. Good sources include whole grains found in cereals, breads, and brown rice, beans, vegetables and fresh or dried fruits. Prunes and bran cereal are tried and true constipation remedies. Stay hydrated.

What is the best product to soften stools?

Stool softeners such as docusate calcium ( Surfak) and docus ate sodium ( Colace ) make stools easier to pass by adding fluid to them. Having softer stool can prevent you from having to strain during bowel movements. Your doctor may recommend one of these products if your constipation is due to childbirth or surgery.

How to get rid of constipation without a doctor?

It may seem obvious, but your diet has a big impact on how you poop. Eat more fiber. Fiber makes stool bulkier and softer so it's easier to pass.

What does CIC mean in bowel movement?

Inability to have a bowel movement. Also, call if you've been having trouble going for more than three weeks and constipation treatments aren't working. You may have a condition called Chronic Idiopathic Constipation (CIC) which means your constipation may be caused by something other than physical or physiological.

How many bowel movements do you have in a week?

According to the National Digestive Diseases Information Clearinghouse, part of the National Institutes of Health, constipation is a condition in which you have fewer than three bowel movements in a week, and your stools are hard, dry, and small, making them painful and difficult to pass.

How many people have constipation?

A lot of Americans -- more than 4 million by some estimates -- deal with constipation on a regular basis. Women have constipation more often than men. This may have to do with the slower movement of food through a woman's intestines, as well as with the effects of female hormones on the GI tract.

What is the best laxative for constipation?

Osmotic laxatives include lactulose, which is prescribed by a doctor, and polyethylene glycol (Miralax), which you can buy over the counter. They pull water back into the colon to soften stool. That makes it easier to pass, but research has found that they only help with constipation.

What is the best medicine for IBS C?

For IBS-C, your doctor may prescribe small doses of an SSRI (selective serotonin reuptake inhibitor) antidepressant, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft).

How to treat IBS C?

There's no single, best approach to treating IBS-C. Often, people use a mix of therapies to get relief. They can include changes in diet, exercise, stress management, and medication. The goal of treatment is more than just easing bowel problems. It's also to soothe the stomachaches, pain, and bloating that are also common symptoms of IBS-C.

What are the different types of stimulants?

Some can be habit-forming and possibly harmful in the long run. Stimulant laxatives include bisacodyl (Correctol, Dulcolax), sennosides (Ex-Lax, Senokot), castor oil, and the plant cascara.

What is the best way to change your mind?

This approach teaches you how to change the way your mind and body react to events. It can include cognitive behavioral therapy, psychotherapy, hypnosis, biofeedback, and relaxation therapy . Most of these therapies help people avoid overreacting to stressful situations and people.

What are some good sources of fiber?

Good sources of fiber include whole-grain bread and cereals, fruits, vegetables, and beans. If you plan to add more high-fiber foods to your diet, do it gradually. Foods affect each person in different ways. Some people get diarrhea and gas when they eat too much fiber, especially all at once.

Can IBS slow down my stool?

They can slow down your stools. So can processed foods such as chips, cookies, and white bread and rice. Keep a symptom journal to figure out which foods your system can handle. Just jot down your IBS symptoms, then note the type and amount of foods you ate during the meals before the symptoms started.

What is the best medication for constipation?

More Options for Opioid-Induced Constipation: Prevention. Osmotic cathartics such as lactulose (Cholac, Constilac, Enulose, Generlac) or polyethylene glycol ( MiraLax) increase water in the bowel and help to move the bowel movement more quickly through the intestine.

What is the FDA approved medication for opiod constipation?

Symproic (naldemedine) In March of 2017, the FDA approved Shionogi's Symproic ( naldemedine ), another peripherally-acting mu -opioid receptor antagonist. Used in adults to treat opioid-induced constipation (OIC) due to opioid use for chronic non-cancer pain or pain related to prior cancer or its treatment.

What is OIC in bowel movements?

Opioid-induced constipation (OIC) results in bowel movements that are infrequent or incomplete due to a side effect of opioid medications. Prevention of OIC is always preferred over waiting to treat it due to the possibility of complications from unaddressed constipation.

What is OIC in pain?

opioid-induced constipation (OIC) in adults with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation.

How to prevent opioid constipation?

Lifestyle Changes to Help Prevent Opioid-Induced Constipation. It's important to address opioid-induced constipation (OIC) with lifestyle changes, even if medications are still needed. Prevention is preferred over treatment, when possible. It's best to start OIC prevention strategies when the opioid is initiated.

How long does Movantik last?

In clinical studies, 1,352 participants received 12.5 milligrams (mg) or 25 mg of Movantik or a placebo (sugar pill) once daily for 12 weeks.

What is the first line of treatment for OIC?

First-Line Medications for OIC. Prevention of opioid-induced constipation (OIC) is always preferred over treatment. Exercise, added fiber in the diet with whole grains, fruits and leafy vegetables, and plenty of fluids can be helpful, but may not work for everyone.

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Diagnosis

Treatment

Self-treatment: Self- care steps that may be helpful in some less- serious cases:
  • Regular exercise for example swimming, walks
  • Increase the content of fiber in food, choose higher fiber cereals and legumes
  • Desist from waiting or holding in the urge to defecate
  • Avoid processed or fast foods, white bread, doughnuts, pastries
  • Drink more fluids, especially water
  • Eat more fruits as they help relieve constipation. For those with edible skins, do not peel them as they are rich in fiber
See a doctor if you notice:
  • Abdominal pain and fever
  • That the last bowel movement was more than 3 days ago
  • Leaking stool
  • Recurrent bleeding from the rectum

See a doctor immediately if you notice:
  • Vomiting occurs and the vomitus has a bright yellow or green coloration (bile)
  • Vomiting and swelling or unusual abdominal distention
  • Severe pain in the rectum
  • Melena or black/tarry stool
  • There are no bowel movements at all

Clinical Trials

Alternative Medicine

Preparing For Your Appointment

  • Treatment for chronic constipation usually begins with diet and lifestyle changes meant to increase the speed at which stool moves through your intestines. If those changes don't help, your doctor may recommend medications or surgery.
See more on mayoclinic.org

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