Thiazide diuretics remain the drugs of first choice for treating hypertension in the African-American hypertensive. The calcium channel blockers (CCBs) are attractive alternatives to thiazides in patients uncontrolled by or intolerant of thiazides or who have specific indications for these agents (eg, angina, severe diastolic dysfunction).
What is the first-line therapy for hypertension in African Americans?
Race has only recently been introduced as a branch-point in the clinical practice guideline algorithm for hypertension(HTN) designed to assist decision making in the treatment of HTN in the U.S 1.This paradigm shift in the treatment of HTN in blacks has provoked an element of controversy reminiscent of the introduction of race-based heart failure (HF) therapy with the …
Are there any clinical trials of HTN for the black patient?
Thiazide diuretics remain the drugs of first choice for treating hypertension in the African-American hypertensive. The calcium channel blockers (CCBs) are attractive alternatives to thiazides in patients uncontrolled by or intolerant of thiazides or who have specific indications for these agents (eg, angina, severe diastolic dysfunction).
Is there a race-based heart failure treatment for HTN?
Apr 06, 2021 · Hypertension is a major problem in Black patients; the incidence and prevalence of cardiovascular and renal complications of hypertension are greater than in other race/ethnicity groups [ 1 ]. The adjusted relative risk of stroke, for example, is more than twice as high in hypertensive Black patients aged 45 to 64 years as compared with ...
Do the HTN guideline committees have good data on black patients?
Apr 01, 2013 · Although either a thiazide diuretic or a CCB is usually considered to be a better choice than an ACE inhibitor or a BB as first‐line monotherapy for African Americans, 11, 27, 35, 36 persons in the JHS taking CCB monotherapy had significantly lower rates of BP control than persons taking thiazide monotherapy.
What is first line treatment for hypertension in African American?
What antihypertensive is best for African American?
What is the first line drug of choice for hypertension?
Which of the following is a first line anti hypertensive drug in black patients with no compelling indications?
Why is lisinopril not recommended for African Americans?
Why are ACE inhibitors not recommended for African black population?
Why is thiazide first line for hypertension?
What is a first line drug?
Which are the drugs for 3rd line treatment of hypertension?
Which of the following group of drugs are the 1st line treatment in both hypertension and heart failure?
What is the first drug of choice for hypertension in India?
Why are ACE inhibitors first line for hypertension?
Do African Americans have high blood pressure?
In cases of special populations, such as African Americans, children, the elderly, and pregnant women, the panel made mention of additional therapies that may benefit each specific group. African Americans have a higher prevalence of hypertension than their Caucasian counterparts. This high blood pressure develops earlier in life ...
What is JNC VI?
The Sixth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI) report, released in 1997, [ 1] recommends a specific strategy for the treatment of hypertension in the United States. These recommendations are based on outcome trials such as the Systolic Hypertension in the Elderly Program (SHEP) ...
How many antihypertensive agents are needed for primary hypertension?
More than 70% of adults treated for primary hypertension will eventually require at least two antihypertensive agents, either initially as combination therapy or as add-on therapy if monotherapy and lifestyle modifications do not achieve adequate blood pressure control. Four main classes of medications are used in combination therapy for ...
Can antihypertensive medications be used for blood pressure?
In some cases, antihypertensive medications may be used to treat the underlying disease regardless of blood pressure. For this reason, these recommendations should be used in conjunction with disease-specific guidelines.
What are the different types of medications used for hypertension?
Four main classes of medications are used in combination therapy for the treatment of hypertension: thiazide diuretics, calcium channel blockers, angiotensin-converting enzyme inhibitors (ACEIs), and angiotensin receptor blockers (ARBs). ACEIs and ARBs should not be used simultaneously.
What is the treatment for proteinuria?
Treatment for patients with chronic kidney disease and proteinuria should include an ACEI or ARB plus a thiazide diuretic or a calcium channel blocker. Patients with diabetes mellitus should be treated similarly to those without diabetes unless proteinuria is present, in which case combination therapy should include an ACEI or ARB. ...
Does monotherapy control blood pressure?
However, in a randomized controlled trial, patients who started on monotherapy eventually achieved blood pressure control similar to that of patients who started on combination therapy .
Does angiotensin converting enzyme inhibitor affect renal function?
A meta-analysis showed that angiotensin-converting enzyme inhibitors—but not angiotensin receptor blockers—reduced the incidence of doubling of the serum creatinine level in patients with diabetes mellitus, but it did not affect progression to end-stage renal disease.