Treatment FAQ

what is the expected treatment length when a patient is using restasis?

by Yvette Hermiston DDS Published 2 years ago Updated 2 years ago

Some people also report recovered tear production after using this medication for long periods of time. Yet, it is important to remember that it may take several weeks for your Restasis treatment to produce a therapeutic effect, and it may even take up to 6 months for you to feel the maximum benefit.

Full Answer

Can Restasis be used long term?

Restasis is meant to be used as a long-term treatment. If you and your doctor determine that Restasis is safe and effective for you, you’ll likely take it long term. Restasis vs. Restasis MultiDose Restasis is approved to treat chronic dry eye.

How much Restasis is in a vial?

Restasis is a liquid emulsion (an oily liquid mixture) that’s used as eye drops. It’s available in one strength: 0.5 mg/mL. Restasis comes as the following two products: Single-use vials. These vials of Restasis can be used for one dose of the drug. Each vial contains 0.4 mL of Restasis. Restasis MultiDose.

How often should I take Restasis for chronic dry eye?

The typical dosage of Restasis for chronic dry eye is one drop into each of your eyes twice daily. You should use the medication about every 12 hours. Note: If you use other eye drops in addition to Restasis, you can probably still use those drops while you’re using Restasis.

How often should I take Restasis for my child?

The typical dosage of Restasis in children ages 16 years and older is the same as it is for adults: one drop into each of your eyes twice daily. Restasis isn’t approved for use in children less than 16 years of age. What if I miss a dose?

How long do you stay on Restasis?

You will be on Restasis for at least 6 months even if your eyes feel better. Many patients may need to continue on Restasis long term or their symptoms will return. Your doctor will tell you when to stop using Restasis.

How long can you use Restasis for dry eyes?

Dry eye is a chronic condition that often requires lifelong therapy to manage symptoms and delay disease progression. Most studies have shown that Restasis must be used for 4 to 6 months to reach its maximum effect of significant symptom relief.

How long should Restasis take to work?

How long does it take for RESTASIS® to work? Chronic Dry Eye is a chronic condition, and you will need to maintain therapy on an ongoing basis. Within 1 month of therapy, your eyes may start producing more of their own tears, but it could take 3 to 6 months after beginning therapy to see an increase in tear production.

How long does a prescription of Restasis last?

by Drugs.com One drop of Restasis MultiDose should be administered into each eye twice daily, amounting to 4 drops total, which means that one bottle should last a little longer than 30 days.

Can you stop taking Restasis?

However, in a moderate dry eye, due to patients' wishes because of the inconvenience and/or expense of chronic medicines, doctors have stopped Restasis after six months to a year of seeing beneficial effects. In many cases the symptoms remain improved for quite some time after stopping the Restasis.

How long can you use steroid eye drops?

Once your eye begins to feel better, reduce the frequency of using the drops to four times a day for a further few days, then stop. Prednisolone eye drops are only meant to be used for a short period of time. Do not use them for longer than one week unless your doctor advises you otherwise.

How long does cyclosporine take to work?

Cyclosporine can provide rapid relief from symptoms. You may see some improvement in symptoms after two weeks of treatment, particularly with stronger doses. However, it may take from three to four months to reach optimal control. Extended use of cyclosporine by transplant patients is well-established.

How often can you use RESTASIS?

How often should I use RESTASIS® or RESTASIS MultiDose ®? Use 1 drop of RESTASIS® or RESTASIS MultiDose ® twice a day in each eye, 12 hours apart—every day.

How long does it take cyclosporine eye drops to work?

When treating dry eyes with Restasis (cyclosporine), it can take 3 to 6 months to notice an increase in tear production or improved symptoms.

How many vials are in a 30 day supply of Restasis?

Restasis (cyclosporine 0.05%, from Allergan) ophthalmic emulsion is now available in a 60-count package (two trays of 30 vials) that provides patients with a 30-day supply.

How does Restasis eye drops work?

Restasis is an immunosuppressive medication that works to reduce inflammation in the tear glands, helping to prevent further damage. Some people also report recovered tear production after using this medication for long periods of time.

What is the pH of Restasis?

Restasis® appears as a white opaque to slightly translucent homogeneous emulsion. It has an osmolality of 230 to 320 mOsmol/kg and a pH of 6.5-8.0. Each mL of Restasis® ophthalmic emulsion contains: Active: cyclosporine 0.05%.

Can Restasis be used with contact lenses?

Restasis® should not be administered while wearing contact lenses. Patients with decreased tear production typically should not wear contact lenses. If contact lenses are worn, they should be removed prior to the administration of the emulsion.

Does Restasis emulsion increase tear production?

Restasis® ophthalmic emulsion is indicated to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. Increased tear production was not seen in patients currently taking topical anti-inflammatory drugs or using punctal plugs.

How often should I take a syringe?

Children younger than 16 years of age—Use and dose must be determined by your doctor. Adults—Put 1 drop in each eye 2 times a day (about 12 hours apart). Children—Use and dose must be determined by your doctor.

How long do you have to wait to put cyclosporine in your eyes?

This medicine can be used with lubricant eye drops (eg, artificial tears). After putting in your artificial tears, you must wait 15 minutes before putting the cyclosporine eye drops into your eyes.

What is cyclosporine used for?

Uses for Restasis. Cyclosporine eye drops are used to increase tear production in patients who have a certain eye condition (eg, keratoconjunctivitis sicca). The medicine belongs to a class of medicines known as immunosuppressants. This medicine is available only with your doctor's prescription.

Does Restasis cause side effects?

Restasis side effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common. Bladder pain.

Can you take two different medicines at the same time?

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Can you use Restasis with Cyclosporine?

Proper use of Restasis. This section provides information on the proper use of a number of products that contain cyclosporine. It may not be specific to Restasis . Please read with care. Take this medicine only as directed by your eye doctor (ophthalmologist).

How long does it take for cyclosporine to relapse?

Upon stopping treatment with cyclosporine, relapse will occur in 50% of patients within 6 weeks. In the majority of patients, rebound disease does not occur after cessation of cyclosporine treatment; although, transformation of chronic plaque psoriasis to more severe forms of psoriasis has been reported.

What is the best treatment for aplastic anemia?

In appropriate patients (i.e., those not immediate candidates for bone marrow transplantation), the combination of cyclosporine (Nonmodified), at doses of 12 mg/kg/day PO in adults or 15 mg/kg/day PO in children and antithymocyte globulin (ATG) has become the standard of care treatment for aplastic anemia. While the response rate to combination therapy is good, relapses are common. Treatment regimens may also include corticosteroids, hematopoietic colony-stimulating factors, and/or cyclophosphamide. In a randomized trial, cyclosporine alone was compared to the combination of cyclosporine and ATG in patients with nonsevere aplastic anemia. In the cyclosporine group, the overall response rate was 46%, with 23% complete responses. A significantly higher response rate of 74% with 57% complete responses was seen with the combination treatment. A high-dose ATG regimen in combination with corticosteroids and cyclosporine resulted in a 78% response rate among patients who had not received previous therapy with ATG or cyclosporine. The cyclosporine regimen consisted of cyclosporine (Nonmodified) 12 mg/kg/day in adults or 15 mg/kg/day in children for 14 days, then cyclosporine doses were adjusted to maintain cyclosporine levels between 200 and 400 ng/mL. The majority of patients who relapsed responded to additional courses of immunosuppressive therapy. Actual survival at 1 and 2 years was 86% and 72%, respectively.

How much should cyclosporine be reduced?

If at any time the serum creatinine increases by >= 50% above baseline, cyclosporine dosage should be reduced by 25—50%. Cyclosporine should be discontinued if reversibility (within 25% of baseline) of the serum creatinine is not achieved after two dosage reductions.

How much cyclosporine should I take for ulcerative colitis?

The American College of Gastroenterology (ACG) states that 2 mg/kg IV is the targeted cyclosporine dose for rescue treatment of acute severe ulcerative colitis (ASUC), with additional studies describing drug levels in the range of 200 ng/mL to 400 ng/mL for efficacy. Other options include infliximab IV. The ACG strongly recommends the use of cyclosporine IV or infliximab IV in patients with ASUC failing to adequately respond to IV corticosteroids after 3 to 5 days. Cyclosporine or infliximab use should be restricted to those failing IVCS therapy except in patients who have contraindications or intolerance to corticosteroids. Higher cyclosporine doses of 4 mg/kg IV do not have greater efficacy based on available data. In some studies, patients received cyclosporine PO after the IV infusion to maintain concentrations until transitioned to other maintenance therapies. In patients with ASUC who achieve remission with cyclosporine treatment, the ACG suggests maintenance of remission with thiopurines or vedolizumab.

How long before transplant can you give cyclosporine?

Initial dosing of cyclosporine (Modified) can be given 4 to 12 hours before transplantation or postoperatively. In newly transplanted patients, the initial dosage of cyclosporine (Modified), is the same as the initial dosage of cyclosporine (Nonmodified).

How long before renal transplant can I take tacrolimus?

5 to 6 mg/kg IV as a single dose 4 to 12 hours before transplantation. IV doses should be given as dilute solutions and administered by slow infusion over 2 to 6 hours. Renal transplant guidelines recommend a calcineurin inhibitor (CNI) such as cyclosporine and an antiproliferative agent plus or minus corticosteroids for initial maintenance immunosuppression. Of note, tacrolimus is suggested as the first-line CNI, and the CNI is suggested to be started before or at the time of transplantation rather than delayed until graft function onset.

Is cyclosporine ophthalmic emulsion contraindicated?

Cyclosporine ophthalmic emulsion is contraindicated in patients with an active ocular infection. Cyclosporine ophthalmic emulsion has not been studied in patients with a history of herpes simplex keratitis (dendritic keratitis). No increase in the incidence of bacterial or fungal ocular infections was reported following the administration of cyclosporine ophthalmic emulsion.

How long does Restasis last?

When you get Restasis from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication.

How often should I take Restasis?

The typical dosage of Restasis for chronic dry eye is one drop into each of your eyes twice daily. You should use the medication about every 12 hours. Note: If you use other eye drops in addition to Restasis, you can probably still use those drops while you’re using Restasis.

How long does it take for Restasis to work?

Depending on how severe your dry eye is, Restasis may take 4 to 6 months to relieve your symptoms. But for some people with mild dry eye, the drug may improve dry eye symptoms within a month. Your eye doctor may recommend a lubricating eye drop for you to use when you first start Restasis treatment.

What is Restasis used for?

Restasis is approved to treat chronic dry eye. With this condition, there’s inflammation or irritation in your eye that causes dryness. Restasis contains the active drug cyclosporine. It belongs to a class of drugs called calcineurin inhibitor immunosuppressants.

How does Restasis work?

It belongs to a class of drugs called calcineurin inhibitor immunosuppressants. Restasis works by increasing your eyes’ natural ability to make tears. Restasis is a liquid emulsion (an oily liquid mixture) that’s used as eye drops. It’s available in one strength: 0.5 mg/mL.

How old is too old to take Restasis?

Restasis is approved for use in children ages 16 years and older. The side effects of Restasis in these children haven’t been reported as being any different than those seen in adults.

Why is it important to dispose of Restasis?

If you no longer need to take Restasis and have leftover medication, it’s important to dispose of it safely. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment.

What does Restasis do for your eyes?

Restasis (cyclosporine) is one of the most popular CNI immunosuppressants, a class of drug that also includes Prograf and Protopic. Drugs in this class are used to treat rheumatoid arthritis, psoriasis, dry eyes, and eczema.

Is there a generic version of Restasis?

Manufacturer Allergan lost their patents for Restasis last year, but we still haven’t seen a generic. What’s going on?

Restasis works best for me. How can I save?

Use a manufacturer coupon or patient assistance program. Manufacturer Allergan offers a savings card to help reduce the cost of Restasis by up to $300, and a patient assistance program that can help qualifying patients get Restasis for free.

Are there other treatments for dry eyes?

Artificial tears. This is the first line of treatment for dry eyes, and it is affordable as it can be purchased without a prescription. One drop four times a day is the place to start, and you may feel relief in a few days. Also, remember that gels and ointments can blur vision because they are greasy.

HEALTH INSURANCE I PAY FOR OR GET THROUGH WORK

About 80% of patients pay less than $35 for a RESTASIS ® or RESTASIS MultiDose® prescription. 2 This cost includes use of RESTASIS ® savings cards.

MEDICAID

About 90% of RESTASIS ® prescriptions have an out-of-pocket cost between $0 and $4 per prescription. 2

NO INSURANCE

The Allergan ® Patient Assistance Program provides certain products to patients in the United States who are unable to afford the cost of their medicine and who meet other eligibility requirements. The RESTASIS ® list price is $586 † per month, plus any additional pharmacy charges depending on where you purchase your medicine.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 1 2 3 4 5 6 7 8 9