Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren't tolerated. It's important to understand "lines of treatment" and how they differ from first line treatment and can play a role in clinical trials.Jun 9, 2020
What is the difference between first-line and second-line drugs?
Your first-line treatment may not work, may start but then stop working, or may cause serious side effects. Your doctor may then suggest a second-line treatment, also called second-line therapy. It is a different treatment that is likely to be effective.
What is second and third line treatment?
THAYR-uh-pee) Treatment that is given when both initial treatment (first-line therapy) and subsequent treatment (second-line therapy) don't work, or stop working.
What does second-line drug mean?
Medical Definition of second-line
: being or using a drug that is not the usual or preferred choice — compare first-line.
: being or using a drug that is not the usual or preferred choice — compare first-line.
What are lines of treatment in cancer?
It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment. If it doesn't cure the disease or it causes severe side effects, other treatment may be added or used instead.
What is a second line antibiotic?
Antibiotics were classified as “first-line” (amoxicillin, TMP-SMX, or erythromycin) or “second-line” (clarithromycin, azithromycin, amoxicillin-clavulanate, cephalosporin, or fluoroquinolone).
What is 3rd line?
Third line support: these are the people you really want to be speaking to if you've got a problem. They're more technically trained, experienced, and knowledgeable. Whatever the issue is, they'll probably be able to fix it, and if they can't, you'll get an on site visit.
What is a line of chemotherapy?
A PICC line (peripherally inserted central catheter line) is used to give someone chemotherapy treatment or other medicines. A PICC line is a long, thin, hollow, flexible tube called a catheter. It is put into one of the large veins of the arm, above the bend of the elbow.
Which is second line Antitubercular?
Injectable antituberculosis drugs- Kanamycin (KAN), amikacin (AMK) and capreomycin (CAP). Less-effective second-line antituberculosis drugs- Ethionamide (ETH)/Prothionamide (PTH), Cycloserine (CS)/Terizidone, P-aminosalicylic acid (PAS).
What does lines of treatment mean?
“Lines of therapy” is the term used to describe the order in which different therapies are given to people as their disease progresses.May 5, 2021
Is chemo worse the second time around?
The effects of chemo are cumulative. They get worse with each cycle. My doctors warned me: Each infusion will get harder. Each cycle, expect to feel weaker.
What is the next step if chemo doesn't work?
Other options. If cancer does not respond to chemotherapy, radiation therapy, or other treatments, palliative care is still an option. A person can receive palliative care with other treatments or on its own.Apr 27, 2022
What is the next treatment after chemotherapy?
After chemotherapy ends, you will have regular appointments with your oncologist or haematologist to monitor your health, manage any long-term side effects, and check that the cancer hasn't come back or spread.