Treatment FAQ

what is the best treatment for severe osteoporisis when i have kidney stones?

by Juwan Pacocha Published 2 years ago Updated 1 year ago

Prescription drugs can help: Calcium channel blockers and alpha-blockers: These relax your ureter, the tube through which pee passes from your kidney to your bladder. A wider ureter will help the stone move more quickly.

Full Answer

Can chronic kidney disease patients with osteoporosis be treated as non-CKD patients?

Chronic kidney disease (CKD) patients with coexisting osteoporosis are becoming common. Many of the therapeutic agents used to treat osteoporosis are known to be affected by the renal function. It is generally thought that osteoporosis in G1 to G3 CKD patients can be treated as in non-CKD patients with osteoporosis.

Which osteoporosis medications are usually tried first?

Which osteoporosis medications are usually tried first? Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Ibandronate (Boniva), a monthly pill or quarterly intravenous (IV) infusion Another common osteoporosis medication is denosumab (Prolia, Xgeva).

What is the best treatment for osteoporosis?

Two infusion medications — those that are injected directly into your vein — have been approved for osteoporosis treatment: Ibandronate (Boniva), infused once every three months. Zoledronic acid (Reclast), infused once a year.

Which osteoporosis medications are contraindicated with kidney disease?

Osteoporosis medications in patients with kidney disease To minimize the risk of chronic kidney disease (CKD) progressing to end-stage renal disease (ESRD), such osteoporosis medications as alendronate (Fosamax) and ibandronate (Boniva) are contraindicated in individuals whose glomerular filtration rate (GFR) is <30%.

Is there a link between kidney stones and osteoporosis?

Kidney and bladder stones (urinary tract stones) and osteoporosis are prevalent, serious conditions for postmenopausal women. Men with kidney stones are at increased risk of osteoporosis; however, the relationship of urinary tract stones to osteoporosis in postmenopausal women has not been established.

How is kidney disease treated with osteoporosis?

Bone metabolic abnormalities in patients with CKD include osteoporotic elements besides renal osteodystrophy. With the advent of novel therapeutic agents for osteoporosis such as denosumab and the recombinant parathyroid hormone teriparatide, it has become practicable to treat osteoporosis even in CKD patients.

What is the safest treatment for severe osteoporosis?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.

Can anything be done for severe osteoporosis?

Treating osteoporosis means stopping the bone loss and rebuilding bone to prevent breaks. Healthy lifestyle choices such as proper diet, exercise, and medications can help prevent further bone loss and reduce the risk of fractures. But, lifestyle changes may not be enough if you have lost a lot of bone density.

Does osteoporosis affect the kidneys?

Patients with osteoporosis often have chronic kidney disease (CKD). CKD is associated with bone and mineral disturbances, renal osteodystrophy, which like osteoporosis leads to a higher risk of fractures.

Can you take Prolia if you have kidney disease?

Kidney function decline is not an adverse reaction that is listed in drug references for Prolia. However, this medication can cause a decrease in calcium (hypocalcemia), sometimes severely. The risk is greater with decreased kidney function, and health care providers are advised to use cautiously in these cases.

What is the newest treatment for osteoporosis?

The U.S. Food and Drug Administration today approved Evenity (romosozumab-aqqg) to treat osteoporosis in postmenopausal women at high risk of breaking a bone (fracture).

What is considered severe osteoporosis?

Severe (established) osteoporosis is defined as having a bone density that is more than 2.5 SD below the young adult mean with one or more past fractures due to osteoporosis.

What is the safest injection for osteoporosis?

Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth.

What is the life expectancy of a person with osteoporosis?

This excess risk is more pronounced in the first few years on treatment. The average life expectancy of osteoporosis patients is in excess of 15 years in women younger than 75 years and in men younger than 60 years, highlighting the importance of developing tools for long-term management.

What is the best and safest treatment for osteoporosis 2022?

Risedronate – Risedronate (brand names: Actonel, Atelvia) reduces the risk of both vertebral and hip fractures. Risedronate is approved for both prevention and treatment of osteoporosis. It can be taken once per day, once per week, or once per month.

Which is better Fosamax or Prolia?

Fosamax (alendronate) is a first-choice treatment for osteoporosis, but taking it can be a hassle. Prevents bone loss. Prolia (Denosumab) is an effective and convenient treatment for osteoporosis if other options haven't worked or aren't appropriate for you.

Which Medications Are Commonly Used For Osteoporosis Treatment?

Bisphosphonates are the most common medications prescribed for osteoporosis treatment. These include: 1. Alendronate (Fosamax) 2. Risedronate (Acto...

How Do Most Osteoporosis Medications Work?

With the exception of teriparatide, osteoporosis medications slow bone breakdown. Healthy bones continuously break down and rebuild.As you age — es...

How Do You Know If You're Taking The Right bisphosphonate?

Drugs in the bisphosphonate class are more alike than they are different. They all help maintain bone density. And, all bisphosphonates have been s...

When Might Other Osteoporosis Medications Be used?

Drugs such as denosumab, teriparatide and abaloparatide can be used by anyone with osteoporosis, but are more likely to be recommended for people w...

What Are Common Side Effects of Bisphosphonate pills?

Bisphosphonate pills aren't absorbed well in the stomach. The main side effects of bisphosphonate pills are stomach upset and heartburn. Generic fo...

Do Intravenous Bisphosphonates Have Advantages Over The Pill form?

Infused forms of bisphosphonates don't cause stomach upset. And it may be easier for some women to schedule a quarterly or yearly infusion than to...

Can Bisphosphonates Hurt Your Bones?

Long-term bisphosphonate therapy has been linked to a rare problem in which the upper thighbone cracks and may break. This injury, known as atypica...

How Long Should You Take A Bisphosphonate For Osteoporosis Treatment?

There's some uncertainty about how long to take bisphosphonates because of a lack of long-term studies. Bisphosphonates have been shown to be safe...

What Happens If You Break A Bone While Taking An Osteoporosis medication?

Osteoporosis medications lower the chance of fracture, but they don't eliminate all risk of breaking a bone. If you have a fracture while on treatm...

Can Medication Alone Successfully Treat Osteoporosis?

Don't rely entirely on medication as the only treatment for your osteoporosis. These practices also are important: 1. Exercise. Weight-bearing phys...

What is the best treatment for osteoporosis?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: 1 Alendronate (Fosamax), a weekly pill 2 Risedronate (Actonel), a weekly or monthly pill 3 Ibandronate (Boniva), a monthly pill or quarterly intravenous (IV) infusion 4 Zoledronic acid (Reclast), an annual IV infusion

Which osteoporosis medication is usually tried first?

Which osteoporosis medications are usually tried first? Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill. Ibandronate (Boniva), a monthly pill or quarterly intravenous (IV) infusion.

What is the condition of bisphosphonates and denosumab?

A very rare complication of bisphosphonates and denosumab is a break or crack in the middle of the thighbone. This injury, known as atypical femoral fracture, can cause pain in the thigh or groin that begins subtly and may gradually worsen.

How does osteoporosis medication work?

Because bone rebuilding cannot keep pace, bones deteriorate and become weaker. Most osteoporosis medications work by reducing the rate at which your bones break down. Some work by speeding up the bone-building process. Either mechanism strengthens bone and reduces your risk of fractures.

How often is romosozumab given?

Romosozumab is given as a monthly injection at your doctor's office. It is a new drug and less is known about long-term side effects, but it is not given to people who have recently had a stroke or heart attack. Treatment stops after 12 monthly doses.

How long can you take bisphosphonate?

These bone-building drugs can be taken for only one or two years and the benefits begin disappearing quickly after you stop. To protect the bone that's been built up, you'll need to start taking a bone-stabilizing medication such as a bisphosphonate.

Does Raloxifene help with bone density?

Current recommendations say to use the lowest dose of hormones for the shortest period of time. Raloxifene (Evista) mimics estrogen's beneficial effects on bone density in post menopausal women, without some of the risks associated with estrogen. Taking this drug can reduce the risk of some types of breast cancer.

What is the most common treatment for osteoporosis?

The most common class of osteoporosis drugs is bisphosphonates, which are antiresorptive chemicals designed to reduce bone loss. Essentially, bisphosphonate therapy slows the rate at which bone cells break down and speeds up the regeneration of new cells.

What is the most common type of osteoporosis medication?

The most common class of osteoporosis drugs is bisphosphonates, which are antiresorptive chemicals designed to reduce bone loss. Other, less common types of osteoporosis medication include the family of drugs called denosumab, teriparatide, and abaloparatide.

Why is osteoporosis a problem?

Essentially, osteoporosis is caused by your body failing to produce new bone tissue fast enough to replace the older bone cells as they break down. Low peak bone density as a young adult is one of the main causes of osteoporosis as an adult.

How to increase bone density?

Increasing your bone density through healthy lifestyle choices can reduce your risk of osteoporosis. Eating the right foods, especially those rich in calcium and the correct amounts of vitamin D, help create stronger, denser bones. If you have dietary restrictions such as a dairy intolerance that make it hard to get enough calcium, consider an over-the-counter supplement. Both men and women under 50 years old need 1,000 milligrams of calcium per day. Women over 50 and men over 70 need 1,200 milligrams per day. Use caution when supplementing your diet with calcium, however, as more than 2,000 milligrams per day can lead to kidney stones and heart disease.

Why is osteoporosis a progressive disease?

Osteoporosis results from too little calcium, leading to weakened bones. It’s a progressive disease and affects about 1 in 3 women aged 50 years and over.

How many women are affected by osteoporosis?

It’s a progressive disease and affects about 1 in 3 women aged 50 years and over. Bones require a significant amount of calcium to maintain their structural integrity. Osteoporosis results from too little calcium, leading to weakened bones. It’s a progressive disease and affects about 1 in 3 women aged 50 years and over.

What are the most common fracture spots for a woman with osteoporosis?

The most common fracture spots for a woman with osteoporosis are the hip, spine, and wrist. Doctors will diagnosis this by viewing the X-ray of your broken bones. They can see whether the loss of bone mass is more than expected for a woman of your age and health history.

Can parathyroidism be treated with surgery?

First and foremost, if you suspect a parathyroid problem like a tumor, see a doctor for testing. If surgery is necessary, most times it can be done on an outpatient basis under a local anesthetic with minimal incisions and complications.

Does calcium help with nerves?

Although calcium is best known for keeping your teeth and bones healthy, it also aids in the transmission of signals in your nerve cells, and it makes your muscles contract.

How to remove kidney stones?

A procedure called percutaneous nephrolithotomy (nef-row-lih-THOT-uh-me) involves surgically removing a kidney stone using small telescopes and instruments inserted through a small incision in your back.

How to remove a small stone in the kidney?

To remove a smaller stone in your ureter or kidney, your doctor may pass a thin lighted tube (ureteroscope) equipped with a camera through your urethra and bladder to your ureter. Once the stone is located, special tools can snare the stone or break it into pieces that will pass in your urine.

What tests can you do if you have a kidney stone?

If your doctor suspects that you have a kidney stone, you may have diagnostic tests and procedures, such as: Blood testing . Blood tests may reveal too much calcium or uric acid in your blood. Blood test results help monitor the health of your kidneys and may lead your doctor to check for other medical conditions. Urine testing.

What is the procedure to break a kidney stone?

For certain kidney stones — depending on size and location — your doctor may recommend a procedure called extracorporeal shock wave lithotripsy (ESWL). ESWL uses sound waves to create strong vibrations (shock waves) that break the stones into tiny pieces that can be passed in your urine.

What is the purpose of a lab analysis of kidney stones?

Analysis of passed stones. You may be asked to urinate through a strainer to catch stones that you pass. Lab analysis will reveal the makeup of your kidney stones. Your doctor uses this information to determine what's causing your kidney stones and to form a plan to prevent more kidney stones.

How to prepare for a kidney appointment?

To prepare for your appointment: Ask if there's anything you need to do before your appointment, such as limit your diet. Write down your symptoms, including any that seem unrelated to kidney stones. Keep track of how much you drink and urinate during a 24-hour period.

How to pass a stone?

You may be able to pass a small stone by: Drinking water. Drinking as much as 2 to 3 quarts (1.8 to 3.6 liters) a day will keep your urine dilute and may prevent stones from forming. Unless your doctor tells you otherwise, drink enough fluid — ideally mostly water — to produce clear or nearly clear urine.

What are the stones in the kidneys?

Also known as nephrolithiasis or renal lithiasis, kidney stones are mineral and acid salt deposits that form and collect inside of the kidneys. These hard deposits, which resemble pebbles or stones, can often be painful, especially while passing through the urinary tract. Typically, these stones form when there is too much calcium, oxalate, uric acid, and other similar substances in the urine. When the urine cannot dilute these, and instead becomes concentrated, kidney stones form. Obesity, dehydration, supplement use, and bowel disorders increase the risk of developing kidney stones. While these may be painful, if caught early, most will not leave permanent damage. Symptoms include:

Why do kidney stones form?

Typically, these stones form when there is too much calcium, oxalate, uric acid, and other similar substances in the urine. When the urine cannot dilute these, and instead becomes concentrated, kidney stones form. Obesity, dehydration, supplement use, and bowel disorders increase the risk of developing kidney stones.

How to reverse osteopenia?

If osteopenia or osteoporosis is diagnosed, you can control the progression of the disease or in some cases even reverse bone thinning via a combination of exercise, diet and dietary supplements, and medication use.

What causes osteoporosis in transplant recipients?

For transplant recipients, osteoporosis is usually caused by a variety of factors related to the end stage chronic disease: immunosuppressive medications, corticosteroids, and decreased levels of physical activity.

What is the normal bone density score for a dexa scan?

This BMD score is then compared to the peak bone mass of a healthy individual which typically occurs at 30 years of age. A normal score is represented as -1.0.

What is the risk of osteoporosis after transplant?

The risk of osteoporosis increases again years after transplantation, with the incidence as high as 40% depending upon the type of organ transplanted. Lung and liver transplant recipients have the highest incidence of osteoporosis-related fractures.

Why is osteoporosis considered a silent disease?

Osteoporosis is commonly referred to as a “silent disease” because signs and symptoms may not be obvious. It is common for individuals who have not been adequately screened to be diagnosed with osteoporosis when they sustain a broken bone (a low level impact fracture).

When should women be screened for bone thinning?

It has been recommended by the United States Preventative Services Task Force that all women over the age of 60 be screened for bone thinning. If a female has a personal history or maternal history of fractures, screening should begin at age 50.

What to do if you don't have a dexa scan?

If you are not having a routine DEXA scan, you should talk to your transplant coordinator or doctor about making a BMD screening part of your regular health and wellness check-ups. A comprehensive exercise program is an important part of preventing and treating osteoporosis.

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