Treatment FAQ

what is the best treatment for bladder cancer?

by Maribel Christiansen IV Published 2 years ago Updated 2 years ago
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Transurethral resection (TURBT) is often done first to find out how far the cancer has grown into the bladder wall. Chemotherapy followed by radical cystectomy (removal of the bladder and nearby lymph nodes) is then the standard treatment. Partial cystectomy is rarely an option for stage III cancers.Sep 20, 2021

Medication

When the cancer has invaded the muscle, radical cystectomy (removal of the bladder) is the standard treatment. Lymph nodes near the bladder are often removed as well. If cancer is in only one part of the bladder, a partial cystectomy may be done instead. But this is possible in only a small number of patients.

Procedures

Bladder Cancer Surgery. Intravesical Therapy for Bladder Cancer. Chemotherapy for Bladder Cancer. Radiation Therapy for Bladder Cancer. Immunotherapy for Bladder Cancer. Targeted Therapy Drugs for Bladder Cancer.

Therapy

The most common chemotherapeutic drug used in bladder cancer is cisplatin. Immunotherapy Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections.

Nutrition

Treatment of bladder cancer depends on the stage of the cancer. Treatment options include different types of surgery (transurethral resection, radical and partial cystectomy, and urinary diversion), radiation therapy, chemotherapy, and immunotherapy. Learn more about how bladder cancer is treated.

What is the newest treatment for bladder cancer?

Mar 13, 2022 · Natural remedies are effective supports and go hand-in-hand with traditional medical treatment to treat bladder cancer safely and effectively. Some of the best natural remedies include baking soda, blackstrap molasses, and lemon.

What is the treatment for Stage 1 bladder cancer?

Sep 28, 2021 · Chemotherapy drugs commonly used for bladder cancer include Mutamycin (mitomycin), Gemzar (gemcitabine), or Valstar (valrubicin). 1 Radiation therapy Immunotherapy with a drug such as Opdivo (nivolumab) System-wide chemotherapy Targeted therapy Clinical trials Summary BCG treatment is a form of immunotherapy for non-muscle invasive bladder …

What are the best hospitals for bladder cancer?

In bladder cancer, adjuvant therapy is usually cisplatin-based chemotherapy (if not given before surgery) or treatment in a clinical trial. Neoadjuvant therapy is treatment that is given before surgery, such as cisplatin-based chemotherapy. The treatments your doctor recommends mainly depend on the stage of bladder cancer.

Is there a cure for bladder cancer?

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What is the latest treatment for bladder cancer?

Advanced and metastatic bladder cancer treatment A notable new FDA approval in December 2019 was enfortumab vedotin (Padcev), approved for advanced bladder cancer patients who have not responded to chemotherapy or immune checkpoint drugs.

Are most bladder cancers curable?

Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable. But even early-stage bladder cancers can come back after successful treatment. For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs.Aug 8, 2020

Does bladder cancer spread fast?

It is an early stage cancer but is always high grade. This means it can grow quickly and might spread. If you have bladder carcinoma in situ your doctor will start treatment straight away.

Do you always need chemo for bladder cancer?

For muscle-invasive bladder cancer, our doctors may recommend chemotherapy before surgery. This treatment approach is called neoadjuvant chemotherapy. Large clinical studies have shown that this method improves cure rates and long-term survival for people with muscle-invasive bladder cancer.

How serious is a tumor in the bladder?

Bladder cancer can be benign or malignant. Malignant bladder cancer may be life threatening, as it can spread quickly. Without treatment, it can damage tissues and organs.Aug 19, 2019

Does size of bladder tumor matter?

CONCLUSIONS: Larger tumor size (>5 cm) is associated with greater length of stay, reoperation, readmission, and death following TURBT. Patients should be counseled appropriately and likely warrant vigilant observation prior to and following hospital discharge.

What are the signs that bladder cancer has spread?

The signs and symptoms of bladder cancer that has spread to other parts of the body include:tiredness or weakness.pain when urinating.difficulty urinating or inability to urinate.pain in the lower back on one side of the body.weight loss.swollen feet.bone pain.Jul 30, 2018

Where does bladder cancer usually spread to first?

Bladder cancer can spread this way. If it does, it usually first spreads to the lymph nodes in the pelvis around the bladder (called perivesicular lymph nodes). From there, it can spread to lymph nodes that are close to major blood vessels that run into the leg and pelvis.7 days ago

Is bladder cancer a terminal?

The general 5-year survival rate for people with bladder cancer is 77%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed. The 5-year survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%.

What happens if bladder cancer is not treated?

Untreated bladder cancer produces significant morbidity, including the following: Hematuria. Dysuria. Irritative urinary symptoms.

Is bladder cancer curable if caught early?

Bladder cancer is usually treatable when caught at an early stage but more challenging to address when found later. Recurrence also poses a risk, even with early-stage tumors, so regular surveillance is essential following treatment or surgery.Apr 8, 2020

How many rounds of chemo do you need for bladder cancer?

Chemotherapy before surgery or radiotherapy usually 3 cycles. Chemotherapy after surgery or radiotherapy, or alongside radiotherapy, can be 6 or more cycles.

Treating Stage 0 Bladder Cancer

Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis). In either case, the cancer has not inv...

Treating Stage I Bladder Cancer

Stage I bladder cancers have grown into the connective tissue layer of the bladder wall but have not reached the muscle layer.Transurethral resecti...

Treating Stage II Bladder Cancer

These cancers have invaded the muscle layer of the bladder wall. Transurethral resection (TURBT) is typically the first treatment for these cancers...

Treating Stage III Bladder Cancer

These cancers have reached the outside of the bladder and might have grown into nearby tissues or organs.Transurethral resection (TURBT) is typical...

Treating Stage IV Bladder Cancer

These cancers have reached the abdominal or pelvic wall (T4b tumors) or have spread to nearby lymph nodes or distant parts of the body. Stage IV ca...

Treating Bladder Cancer That Progresses Or Recurs

If cancer continues to grow during treatment (progresses) or comes back (recurs), your treatment options will depend on where and how much the canc...

Which Treatments Are Used For Bladder Cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: 1. Surgery 2. Intravesical th...

Which Doctors Treat Bladder Cancer?

Depending on your options, you can have different types of doctors on your treatment team. The types of doctors who treat bladder cancers include:...

Making Treatment Decisions

It’s important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decisi...

Help Getting Through Treatment

Your cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or c...

What is the treatment for bladder cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: Bladder Cancer Surgery. Intravesical Therapy for Bladder Cancer. Chemotherapy for Bladder Cancer. Radiation Therapy for Bladder Cancer. Immunotherapy for Bladder Cancer. Targeted Therapy Drugs for Bladder Cancer.

What are the things to consider when considering cancer treatment?

Some important things to consider include: Your age and expected life span. Any other serious health conditions you have. The stage and grade of your cancer. The likelihood that treatment will cure your cancer (or help in some other way) Your feelings about the possible side effects from treatment.

What kind of doctor treats cancer?

Based on your treatment options, you might have different types of doctors on your treatment team. These doctors could include: 1 Urologists: surgeons who specialize in treating diseases of the urinary system and male reproductive system 2 Radiation oncologists: doctors who treat cancer with radiation therapy 3 Medical oncologists: doctors who treat cancer with medicines such as chemotherapy and immunotherapy

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

What are the things to consider when making a treatment decision?

Some important things to consider include: Your age and expected life span.

What are the services offered by the American Cancer Society?

These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. The American Cancer Society also has programs and services – including rides to treatment, lodging, and more – to help you get through treatment.

Is treatment information given here official policy of the American Cancer Society?

The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

What is the treatment for bladder cancer?

Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections. The approach is still being researched and there is a lot left to learn, but clinical studies have shown that immunotherapy holds a lot of promise in its ability to treat a wide range of malignancies, including some types of bladder cancer.

What is the procedure to remove a bladder tumor?

Cystectomy (Bladder Removal) Surgery. When bladder cancer tumors completely invade the bladder’s muscular wall, the standard of care is to perform bladder removal surgery. Typically, complete removal of the bladder ( radical cystectomy) is required. Partial cystectomy is rare because the requirements are that the tumor is easily accessible ...

How does intravenous drug therapy work?

Intravesical drug therapy involves placing medicines directly into the bladder via a urethral catheter to lower the recurrence rates of bladder tumors. It is usually used for multiple carcinomas in situ that cover a large area (5 centimeters-plus), or for high-grade or high-stage tumors.

What is the procedure called when a camera is passed through the urethra?

Cystoscopy is an outpatient procedure during which a thin, lighted tube with a camera is passed through the urethra into the bladder, allowing your doctor to see the inside of the bladder.

How does chemotherapy work?

Chemotherapy uses chemical agents to interfere with replication and other normal functions of cells, resulting in tumor shrinkage or cancer cell death . The use of two or more chemotherapy drugs together has been found to be more effective than a single drug alone. There are several types of chemotherapy.

What percentage of bladder cancer is superficial?

Bladder Cancer Liver Gallbladder and Pancreas Urological Conditions Cancer. Over 75 percent of bladder cancers remain confined to the lining of the bladder and do not invade the bladder wall. These are called nonmuscle-invasive bladder cancer, or superficial bladder cancer, and when managed well, they are associated with excellent prognoses.

Why is partial cystectomy rare?

Partial cystectomy is rare because the requirements are that the tumor is easily accessible and small in size, and that there are no tumors in the rest of the bladder. This approach is usually used only if the cancer has not left its site of origin.

What is bladder cancer?

Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller to store urine made by the kidneys.

What is it called when you have cancer in your bladder?

Cancer that is in the lining of the bladder is called superficial bladder cancer. Cancer that has spread through the lining of the bladder and invades the muscle wall of the bladder or has spread to nearby organs and lymph nodes is called invasive bladder cancer. See the following PDQ summaries for more information:

How does chemo work?

When chemotherapy is taken by mouth or injected into a vein or muscle , the drugs enter the bloodstream and can reach cancer cells throughout the body ( systemic chemotherapy ). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas ( regional chemotherapy ). For bladder cancer, regional chemotherapy may be intravesical (put into the bladder through a tube inserted into the urethra). The way the chemotherapy is given depends on the type and stage of the cancer being treated. Combination chemotherapy is treatment using more than one anticancer drug.

What is an IVP pyelogram?

Intravenous pyelogram (IVP): A series of x-rays of the kidneys, ureters, and bladder to find out if cancer is present in these organs. A contrast dye is injected into a vein. As the contrast dye moves through the kidneys, ureters, and bladder, x-rays are taken to see if there are any blockages.

Where does cancer spread?

cancer has spread from the bladder to the wall of the abdomen or pelvis; or. cancer has spread to lymph nodes that are above the common iliac arteries (major arteries in the pelvis). In stage IVB, cancer has spread to other parts of the body, such as the lung, bone, or liver.

Where is urine made in the body?

Anatomy of the male urinary system (left panel) and female urinary system (right panel) showing the kidneys, ureters, bladder, and urethra. Urine is made in the renal tubules and collects in the renal pelvis of each kidney.

What type of cancer begins in squamous cells?

Squamous cell carcinoma: Cancer that begins in squamous cells (thin, flat cells lining the inside of the bladder). Cancer may form after long-term infection or irritation. Adenocarcinoma: Cancer that begins in glandular cells that are found in the lining of the bladder.

How to diagnose bladder cancer?

Tests and procedures used to diagnose bladder cancer may include: Using a scope to examine the inside of your bladder (cystoscopy). To perform cystoscopy, your doctor inserts a small , narrow tube (cystoscope) through your urethra. The cystoscope has a lens that allows your doctor to see the inside of your urethra and bladder, ...

How does radiation therapy help bladder cancer?

Radiation therapy. Radiation therapy uses beams of powerful energy, such as X-rays and protons, to destroy the cancer cells. Radiation therapy for bladder cancer usually is delivered from a machine that moves around your body, directing the energy beams to precise points.

What is a cystoscope?

Cystoscopy allows your doctor to view your lower urinary tract to look for abnormalities, such as a bladder stone. Surgical tools can be passed through the cystoscope to treat certain urinary tract conditions.

What is retrograde pyelogram?

Retrograde pyelogram is an X-ray exam used to get a detailed look at the upper urinary tract. During this test, your doctor threads a thin tube (catheter) through your urethra and into your bladder to inject contrast dye into your ureters. The dye then flows into your kidneys while X-ray images are captured.

How to get a follow up on bladder cancer?

Get a schedule of follow-up tests and go to each appointment. When you finish bladder cancer treatment, ask your doctor to create a personalized schedule of follow- up tests. Before each follow-up cystoscopy exam, expect to have some anxiety. You may fear that cancer has come back or worry about the uncomfortable exam.

What is the procedure called when you remove a sample of tissue for testing?

Removing a sample of tissue for testing (biopsy). During cystoscopy, your doctor may pass a special tool through the scope and into your bladder to collect a cell sample (biopsy) for testing. This procedure is sometimes called transurethral resection of bladder tumor (TURBT). TURBT can also be used to treat bladder cancer.

What is a low grade bladder cancer?

Low-grade bladder cancer. This type of cancer has cells that are closer in appearance and organization to normal cells (well differentiated). A low-grade tumor usually grows more slowly and is less likely to invade the muscular wall of the bladder than is a high-grade tumor. High-grade bladder cancer.

The Early-Stage Bladder Cancer Treatment

Jennifer Welsh is a Connecticut-based science writer and editor with over ten years of experience under her belt. She’s previously worked and written for WIRED Science, The Scientist, Discover Magazine, LiveScience, and Business Insider.

Who Can Use BCG?

BCG is a treatment for early-stage bladder cancer that has not yet invaded the muscle of the bladder wall. Called non-muscle invasive bladder cancers (NMIBCs) or in situ bladder cancers, these account for about half of all bladder cancers. 3

What to Expect During BCG Treatment

First, make sure you haven’t had any fluids for four hours before the treatment. Right before you go into the treatment room your doctor or nurse will have you empty your bladder. 2

How to Prepare

To prepare for the BCG treatment, your doctor will likely have you undergo surgery to remove any visible cancer in the bladder. The surgery is called transurethral resection of bladder tumor (TURBT) and is usually done about two weeks before BCG therapy.

When to See a Doctor

There are a few side effects that can be especially dangerous, so make sure to talk to your doctor if you notice that you: 2

Other Treatments for Bladder Cancer

For many early-stage bladder cancers, BCG is the best option for treatment. Other treatments for bladder cancer include:

Summary

BCG treatment is a form of immunotherapy for non-muscle invasive bladder cancer. It is administered into the bladder through a catheter. It then activates the body's immune system to attack the cancer cells.

What is the best treatment for bladder cancer?

In general, the main treatment options for bladder cancer are: Surgery. Chemotherapy. Immunotherapy (local and systemic) Targeted therapy. Radiation therapy. To learn more about the basics of each type of treatment, read this guide’s Types of Treatment section.

What is stage IV bladder cancer?

Metastatic urothelial cancer (stage IV) If bladder cancer has spread to another part of the body, doctors call it metastatic bladder cancer. If this happens, it is a good idea to talk with doctors, usually medical oncologists, who have experience in treating it.

What is stage 0A in TURBT?

People with low-grade noninvasive bladder cancer (stage 0a) are treated with TURBT first. Low-grade noninvasive bladder cancer rarely turns into aggressive, invasive, or metastatic disease, but patients are at risk for developing more low-grade cancers throughout their life.

What is neoadjuvant therapy?

Neoadjuvant therapy is treatment that is given before surgery, such as cisplatin-based chemotherapy. The treatments your doctor recommends mainly depend on the stage of bladder cancer. Treatment for cancer in the renal pelvis and/or ureter follow the same treatment plans based on the stage of the disease.

What is the first line of treatment for urothelial cancer?

The first treatment a person is given for advanced urothelial cancer is called first-line therapy . If that treatment stops working, then a person receives second-line therapy.

Can metastatic urothelial cancer be treated?

A combination of treatments may be used to help manage the cancer. There are no methods to permanently cure metastatic urothelial cancer for most people. The goals of treatment are to slow the spread of cancer, delay its growth, shrink the tumor (called remission), and extend life for as long as possible.

Can you get a TURBT before surgery?

Sometimes, people with muscle-invasive bladder cancer receive systemic chemotherapy first, before surgery.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatments include surgery, chemotherapy, and biological therapy.
Medication

Immunotherapy: This therapy helps boost your immune system fight against the cancerous cells.

Atezolizumab . Durvalumab . Avelumab


Chemotherapy: Injection of cancer-fighting medications into the bladder through a catheter to kill the harmful cells.

Gemcitabine/Cisplatin . Methotrexate/ Vinblastine/Doxorubicin/Cisplatin (called MVAC) . Cisplatin/ Methotrexate/Vinblastine (called CMV) . Carboplatin/Paclitaxel . Docetaxel

Procedures

Transurethral resection of bladder tumor (TURBT): An instrument called a resectoscope is inserted into the bladder through the urethra which is used to remove abnormal tissues or tumors.

Cystectomy: Removal of a part of bladder is called as partial cystectomy or complete bladder removal which is called as radical cystectomy.

Therapy

Radiation therapy:High-energy radiation is used to kill the cancer cells.

Nutrition

Foods to eat:

  • Focus on starchy carbohydrates such as bread, pasta, rice or potatoes
  • Whole grains are highly recommended
  • Eat a variety of fruit and vegetables daily
  • Include lean protein such as meat, fish, eggs, beans or pulses
  • Have milk and cheese

Foods to avoid:

  • Eggs, total fat, butter
  • Soft drinks, caffeine, chlorinated surface water, sugar

Specialist to consult

Urologist
Specializes in the urinary tract disease.
Oncologist
Specializes in the diagnosis and treatment of cancer.

Preparing For Your Appointment

  • Diagnosing bladder cancer
    Tests and procedures used to diagnose bladder cancer may include: 1. Using a scope to examine the inside of your bladder (cystoscopy).To perform cystoscopy, your doctor inserts a small, narrow tube (cystoscope) through your urethra. The cystoscope has a lens that allows your doct…
  • Determining the extent of the cancer
    After confirming that you have bladder cancer, your doctor may recommend additional tests to determine whether your cancer has spread to your lymph nodes or to other areas of your body. Tests may include: 1. CTscan 2. Magnetic resonance imaging (MRI) 3. Positron emission tomog…
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