
Explore
Two or more of the following issues also increases the risk of developing refeeding syndrome:
- a BMI of less than 18.5
- unintentionally losing 10 percent of body weight in the past 3–6 months
- consuming little or no food in the past 5 consecutive days or more
- a history of alcoholism or drug abuse
- receiving some treatments, such as insulin, diuretics, chemotherapy drugs, radiation therapy, and antacids
What is refeeding syndrome and how to prevent it?
- Loose motions and diarrhea
- Low calcium level hypocalcaemia
- Tachycardia
What are the causes and symptoms of refeeding syndrome?
- You've lost 10% or more of your normal body weight in the last three to six months.
- Your BMI is under 18.
- You have not eaten for five days in a row.
- You have been diagnosed with an eating disorder, including anorexia or bulimia nervosa.
- You use alcohol.
- You are recovering from surgery.
- You are having a hard time controlling your diabetes.
What do you monitor for refeeding syndrome?
Avoid supplement drinks as these may precipitate re-feeding due to calorie load (unless prescribed by a dietitian). In patients at high and severe risk, limit all oral intake during initial 24 hours of refeeding Accurately record all oral intake on fluid balance sheet and food record chart What are the clinical features?
How to prevent refeeding?

What happens to the body during refeeding?
In the refeeding process, the release of insulin into the bloodstream can decrease phosphorus, potassium, magnesium, calcium and sodium levels in the bloodstream. This causes refeeding syndrome. Symptoms of refeeding syndrome include lightheadedness, fatigues, a drop in blood pressure and a drop in heart rate.
What should I eat when refeeding?
Days of refeeding Aim to consume most of your additional calories from carb-rich foods, such as whole grains, pasta, rice, potatoes, and bananas, as carbs have been shown to increase leptin levels more than protein or fat ( 2 , 10 ). You can continue to eat protein and fat at each meal.
Is refeeding painful?
Science and clinical experience both reveal that the refeeding process may be uniquely painful for each individual – independent of weight. Refeeding can be as physically and psychologically uncomfortable for someone who is overweight, as it can be for someone of average weight, or for someone who is underweight.
What are the symptoms of refeeding?
In patients experiencing refeeding syndrome, a dangerous shift in fluids and electrolytes occurs within the body, resulting in compromised cardiovascular status, respiratory failure, seizures and even death.
How long does the refeeding process take?
Refeeding may take up to 10 days, with monitoring afterward. In addition, refeeding often occurs alongside other serious conditions that typically require simultaneous treatment.
How long should a refeed last?
Refeeds while dieting should occur weekly, bi-weekly, or every 3 to 4 weeks depending on what our body fat percentage is, how aggressive our caloric deficit is, and the amount of time that we're dieting for. In general, if you have a lower body fat percentage, the more frequent your refeeds need to be.
What foods should you avoid with refeeding syndrome?
Doctors should refeed patients slowly, starting with 1,000 calories per day and increasing by 20 calories each day, to prevent refeeding syndrome. Administering oral vitamins and minerals such as phosphate, calcium, magnesium and potassium can also help prevent refeeding syndrome.
How long does it take to recover from malnutrition?
The recovery rate for oedematous malnutrition was 57.6% (95% CI 52.9% to 62.2%) whereas the recovery rate for non-oedematous malnutrition was 63.8% (95% CI 61.1% to 66.5%). The median time to recovery was 16 days (IQR=11–28).
What are the risks of refeeding syndrome?
Who's at Risk for Refeeding Syndrome?Anorexia nervosa.Chronic alcoholism.Conditions that cause malabsorption, such as inflammatory bowel disease, chronic pancreatitis, cystic fibrosis, and short bowel syndrome.Diet practices such as prolonged fasting or low energy diet.Excessive use of antacids or diuretics.More items...•
What are the 3 stages of starvation?
Synopsis: Information regarding the stages of starvation and the effect malnutrition has on the human body. After approximately a week of fasting, a person's brain starts to use ketone bodies, as well as glucose, for sources of energy....Defining the Word "Starvation"Disease.Anorexia.Deprivation.Prolonged fasting.
How do I start to eat again?
16 Ways to Increase Your AppetiteEat Small Meals More Frequently. Share on Pinterest. ... Eat Nutrient-Rich Foods. ... Add More Calories to Your Meals. ... Make Mealtime an Enjoyable Social Activity. ... Trick Your Brain With Different Plate Sizes. ... Schedule Meal Times. ... Don't Skip Breakfast. ... Eat Less Fiber.More items...•
How long can you go without food?
Although a person can last from 20-60 days without eating anything, human bodies almost all give up within 40 days. However, there have been cases of hunger strikes around the world where people managed to go 70 days without eating anything at all.
What is refeeding syndrome?
Refeeding syndrome can be defined as the potentially fatal shifts in fluids and electrolytes that may occur in malnourished patients receiving artificial refeeding (whether enterally or parenterally5). These shifts result from hormonal and metabolic changes and may cause serious clinical complications.
What are the biochemical features of refeeding syndrome?
The hallmark biochemical feature of refeeding syndrome is hypophosphataemia. However, the syndrome is complex and may also feature abnormal sodium and fluid balance; changes in glucose, protein, and fat metabolism; thiamine deficiency; hypokalaemia; and hypomagnesaemia.16.
What is the role of insulin surge in refeeding syndrome?
Also, the insulin surge causes a greatly increased uptake and use of phosphate in the cells. These changes lead to a deficit in intracellular as well as extracellular phosphorus.
Is refeeding syndrome a controlled disease?
Refeeding syndrome is a well described but often forgotten condition. No randomised controlled trials of treatment have been published, although there are guidelines that use best available evidence for managing the condition. In 2006 a guideline was published by the National Institute for Health and Clinical Excellence (NICE) in England and Wales.
Is refeeding syndrome fatal?
Summary points. Refeeding syndrome is a potentially fatal condition, caused by rapid initiation of refeeding after a period of undernutrition.
Why does refeeding syndrome occur?
Takeaway. Refeeding syndrome can develop when someone who is malnourished begins to eat again. The syndrome occurs because of the reintroduction of glucose, or sugar. As the body digests and metabolizes food again, this can cause sudden shifts in the balance of electrolytes and fluids.
What happens when you refeed too quickly?
Refeeding syndrome can occur when food is reintroduced too quickly after a period of starvation or malnourishment. This can lead to electrolyte imbalances and severe complications that can be fatal.
What is the highest risk of refeeding syndrome?
The risk is high when a person has an extremely low body mass index. People who have recently lost weight quickly, or who have had minimal or no food before starting the refeeding process are also at significant risk.
What happens when food is reintroduced?
When food is reintroduced, the body no longer has to rely on reserves of fat and protein to produce energy. However, refeeding involves an abrupt shift in metabolism. This occurs with an increase in glucose, and the body responds by secreting more insulin. This can result in a lack of electrolytes, such as phosphorous.
Can refeeding cause hypophosphatemia?
Refeeding syndrome can cause hypophosphatemia, a condition characterized by a phosphorus deficiency. It can also lead to low levels of other important electrolytes. The harmful effects of refeeding syndrome are widespread, and they can include problems with the: heart.
What is refeeding syndrome?
Refeeding syndrome is a potentially life-threatening condition that can occur when a person who is severely malnourished begins to eat and drink again. Electrolyte imbalances can affect the heart, brain, and other major organs and lead to serious complications which can be fatal. 22 Adhering to slow and steady rehydration and calorie restoration protocol is essential to a person's safety and wellbeing. Long-term follow-up care for people who have been treated for malnutrition will need to include many different healthcare professionals depending on the underlying cause, including mental health professionals, specialists, and registered dieticians.
Why do people refeed?
Refeeding syndrome has been observed for decades in people who are starving as the result of capture (such as prisoners of war or people who were in concentration camps), famine, poverty, or illness. When medical professionals encountered severely malnourished people in the past, the assumption was that these starving individuals should be allowed to eat and drink normally—or even take in large quantities of nourishment—to address their prolonged hunger and begin to heal their bodies.
What is the safest rate of refeeding for severely malnourished patients who are in the hospital?
In general, the safest rate of refeeding for severely malnourished patients who are in the hospital is starting at about half of what their goal caloric intake will be, and gradually increasing how many calories they eat. 21. Depending on the underlying cause a person's malnutrition, other intervention may be needed.
What happens when a person is refeeding?
When refeeding syndrome occurs, the medical team will need to take prompt action to correct the life-threatening imbalances. Once a malnourished person's health is more stable, the plan of care will need to be changed to prevent further complications.
What happens when you refeed?
If a person is given nutrition and hydration too quickly, it can cause dangerous imbalances in electrolyte levels. When these changes are sudden, it can lead to problems with the heart, kidneys, and brain, ...
What is the best way to maintain weight after refeeding?
Once patients have been treated for malnutrition, maintaining weight and nutrition after refeeding usually requires a team of doctors and allied health professionals. Dietitians and nutrition specialists can help people ensure they are eating a balanced diet as well as eating enough to meet their body's energy needs.
What are the risk factors for refeeding syndrome?
You are most at risk for refeeding syndrome if you have any of these risk factors: 12. You have had little or nothing to eat for 10 or more days in a row. Your body mass index (BMI) is less than 16. Your blood tests show low levels of phosphate, potassium, sodium, or magnesium.
What electrolytes are needed for refeeding?
There is complex interplay among potassium, phosphorus and other key electrolytes in the refeeding process. As calories are reintroduced, it is essential to monitor phosphorus, potassium and other electrolyte levels in the body.
Can refeeding syndrome cause heart failure?
Avoiding Refeeding Syndrome. Increasing caloric intake without proper blood monitoring too quickly can result in refeeding syndrome, a dangerous metabolic imbalance marked by a shift in fluids and electrolytes within the body that can lead to heart failure. Read More.
What Is Refeeding?
When you don’t get the proper amount of food in your body, you begin to suffer from malnutrition. Recovering from severe malnutrition isn’t as simple as starting to eat normally again. You will need to be admitted to the hospital, and doctors will prescribe a special formula of artificial nutrients to replenish your body.
What Causes Refeeding Syndrome?
Refeeding syndrome is a complication of treatment for malnutrition. It’s essential to replace lost nutrients because malnutrition has serious health consequences. You can develop loss of body fat and muscle wasting. It can also lead to poor bone health, anemia, or vitamin deficiencies.
Complications From Refeeding Syndrome
If you develop refeeding syndrome, it can affect different organ systems in your body. The effects can be life-threatening. Complications from refeeding syndrome may include:
Who's at Risk for Refeeding Syndrome?
Refeeding syndrome is a complication of refeeding. You're only at risk if you have malnutrition so severe that you need artificial nutrients for it. Most refeeding patients are already in the hospital for treatment.
Treatment for Refeeding Syndrome
Experts believe that preventing refeeding syndrome is the most effective course of action. If you're being treated with refeeding, your doctor may monitor the electrolyte levels in your body. If there's an imbalance, your doctor will adjust the formula of nutrients to prevent refeeding syndrome.
What is RFS in nutrition?
Even though well tolerated, nutritional treatment has a potential risk of complications, including RFS, which is an exacerbated response to the metabolic change from a starvation to a fed state as a consequence of large amount of food in the replenishment phase. RFS is characterized by an imbalance of electrolytes (mainly phosphate, potassium, ...
What is tube feeding?
Enteral nutrition (tube feeding) is indicated for extremely malnourished patients (e.g., very low BMI) or patients who are unable to consume enough food to reach the energy targets. Parenteral nutrition is indicated when oral and/or enteral nutrition are insufficient or in the case of failure of the gut function.
What is the metabolic response to the switch from starvation to a fed state in the initial phase of nutritional answer
Refeeding syndrome (RFS) is the metabolic response to the switch from starvation to a fed state in the initial phase of nutritional therapy in patients who are severely malnourished or metabolically stressed due to severe illness.
What is RFS characterized by?
RFS is characterized by an imbalance of electrolytes (mainly phosphate, potassium, and magnesium), vitamin disturbances ( e.g., vitamin B1 thiamine deficiency), and fluid imbalances , as well as limited organ functions, in some cases leading to mortality [8,9,10,11,12].
What is the goal of RFS?
The overall objectives in the treatment of RFS complications are to stabilize the patient’s general clinical state, to reverse the medical complications, as well as to restore nutritional needs and weight. The sooner the RFS complications are treated, the lower the risk of damage to patient’s vital organs.
Can RFS cause tachycardia?
Peripheral edema, tachypnea, and tachycardia are the most commonly observed clinical symptoms in patients suffering RFS.
Is RFS a clinical manifestation?
This is primarily due to the fact that the clinical manifestations of RFS are nonspecific, leading to RFS frequently being overlooked, underdiagnosed, and subsequently untreated.
What is refeeding syndrome?
Refeeding. Refeeding syndrome was first described in Japanese prisoners of war from World War II who had been starved while imprisoned. It is a complex of biological symptoms that can occur when food is reintroduced to people who are starved or severely malnourished. People who have not eaten for 5 or more days are at an increased risk ...
Why is refeeding syndrome confused with renourishment?
Refeeding syndrome may be confused with renourishment because they sound as if they might be similar processes. However, renoursihment is actually the process of reintroducing food to people who are malnourished or starved such as those who suffer from Anorexia Nervosa.
What happens when you are starved?
When the body is starved it implements various physiological mechanisms to conserve muscle tissue and slow the metabolism. To achieve this various hormones are increased or decreased, the body begins to burn ketones rather than glucose, and electrolyte stores are used.
Does refeeding increase insulin?
Refeeding increases insulin, decreases glucagon. In refeeding syndrome, food is introduced after prolonged starvation and this leads to an increase in insulin and decrease in glucagon. The body increases metabolism and switches from using ketones as the primary energy source back to glucose.
Can refeeding syndrome cause death?
When they are deranged as in refeeding syndrome, it can result in cardiac arrhythmias, confusion, convulsions, coma, or even death. To avoid refeeding sydrome, severely malnourished individuals are usually given milk as a main energy source because it is generally well tolerated and naturally has high phosphate levels.
Why is refeeding important?
Refeeding, nutritional plans, and weight restoration are crucial parts of the medical stabilization process which is necessary in order to proceed with treatment and eventually achieve recovery. There are many serious and some deadly complications that arise during refeeding process which is why medical supervision is of the utmost importance.
What are the causes of refeeding syndrome?
Heart failure. Arrhythmias (abnormal heart rhythms) Respiratory failure. Muscle breakdown. Death. It is for these reasons that the refeeding syndrome should be avoided and if it occurs, patients should be closely followed by specialized doctors.
What is the most dangerous complication of refeeding?
The Dangers of Refeeding Syndrome. The most feared and potentially deadly complication of the refeeding process is the refeeding syndrome. Refeeding syndrome occurs when patients that have been starved begin to eat and metabolize calories. The body shifts from a catabolic state (a state of breaking down tissues for nutrients) ...
What is the purpose of starving the brain?
It is for this reason that nutritional rehabilitation and weight restoration are key components of the recovery process.
Is there enough data to refeed adults?
While the literature seems to be shifting from a “start low and go slow” approach to refeeding the malnourished patient, nutritional rehabilitation must remain tailored to individual patients. There is no sufficient data on how to refeed adults.
Can you refeed a malnourished patient?
There are clear guidelines regarding when malnourished patients should go through the refeeding process in specialized units or a hospital setting: weight < 70 ideal body weight, bradycardia (slow heart rate), arrhythmias, and unstable vital signs. There are, however, no clear guidelines on how to refeed patients once they start the process.
Is there a clear guideline for refeeding patients?
There are, however, no clear guidelines on how to refeed patients once they start the process. The current refeeding practices are based on experience and consensus statements rather than published data thus lack scientific evidence to support such statements. The refeeding mantra for many years has been “start low and go slow”.

What Is Refeeding Syndrome?
Symptoms
- Refeeding syndrome can come on suddenly and have devastating consequences. Symptoms of refeeding syndrome include:5 1. Abdominal pain 2. Bowel changes 3. Confusion 4. Difficulty breathing 5. Fatigue 6. Heart arrhythmias 7. Increased heart rate 8. Low blood pressure 9. Muscle pain 10. Nausea 11. Rapid weight gain (from fluid retention) 12. Paralysis 13. Seizures 14. Swelli…
Causes
- Refeeding syndrome has been observed for decades in people who are starving as the result of capture (such as prisoners of war or people who were in concentration camps), famine, poverty, or illness. Initially, healthcare providers allowed starving individuals to eat and drink normally to address their prolonged hunger and allow their bodies to heal. However, instead of returning to h…
Risk Factors
- Refeeding syndrome occurs in people who are malnourished, most commonly in those who have been hospitalized.11 Other causes of malnutrition include an inability to take food by mouth due to an injury or condition such as dental problemsor oral surgery, an inability to swallow, a gastrointestinal disease that impacts digestion (malabsorption), or weight-loss surgery. In additi…
Diagnosis
- People who are severely malnourished are typically admitted to the hospital to begin the refeeding and rehydration process. This allows for close monitoring of vital signs and bloodwork to quickly diagnose refeeding syndrome. Bloodwork can often show potentially life-threatening complications before outward symptoms are evident. Your healthcare team will closely monitor …
Treatment and Prevention
- Prompt action is needed to correct the life-threatening imbalances of refeeding syndrome. When a person is being refed and rehydrated after a period of malnutrition, it's important that the process is slow and deliberate, allowing the body enough time to adjust. If a person is going to need tube feeding, healthcare providers usually will try to ensure they are well-hydrated and don'…
A Word from Verywell
- Refeeding syndrome is a potentially life-threatening condition that can occur when a person who is severely malnourished begins to eat and drink again. Electrolyte imbalances can affect the heart, brain, and other major organs and lead to serious complications which can be fatal.19 Adhering to slow and steady rehydration and calorie restoration protocol is essential to a person…