Treatment FAQ

what is radical prostatectomy aggressive treatment

by Elody Lindgren Published 2 years ago Updated 2 years ago
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If your medical team determines that your prostate cancer has become aggressive and needs to be treated, an operation called radical prostatectomy — removal of the prostate — is typically the first-line treatment. This surgery removes the prostate gland and surrounding tissues such as the seminal vesicles and sometimes nearby lymph nodes.

A radical prostatectomy is surgery to remove the prostate gland and seminal vesicles (and sometimes nearby lymph nodes) after a prostate cancer diagnosis. It is one treatment option for patients with localized prostate cancer.

Full Answer

What is a radical prostatectomy?

Radical Prostatectomy. Removing the entire prostate gland through surgery, known as a radical prostatectomy, is a common option for men whose cancer has not spread. For men with advanced or recurrent disease, other surgical procedures may be chosen, such as removal of lymph nodes, which are initial landing spots for the spread of prostate cancer.

Can hormone therapy help with radical prostatectomy?

Radical Prostatectomy. Hormone therapy may be recommended for men who have cancer found in their lymph nodes at the time of surgery; for these men, hormone therapy following surgery has been shown to help patients live longer. Multiple clinical trials have not demonstrated a significant benefit to using hormone therapy before surgery, however.

How can minimally invasive prostate surgery help speed recovery after radical prostatectomy?

Minimally invasive techniques — and most commonly, robot-assisted surgery — help speed recovery after radical prostatectomy, since they cause less blood loss, less pain and shorter hospital stays. At Roswell Park, 100% of radical prostatectomies are performed with robot assistance.

Who should undergo radical prostatectomy?

Radical prostatectomy can cure prostate cancer in men whose cancer is limited to the prostate. Who Should Undergo Radical Prostatectomy? Men younger than age 75 with limited prostate cancer who are expected to live at least 10 more years tend to get the most benefit from radical prostatectomy.

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What is best treatment for aggressive prostate cancer?

Hormone therapy is often used to treat advanced prostate cancer to shrink the cancer and slow its growth. Hormone therapy is sometimes used before radiation therapy to treat cancer that hasn't spread beyond the prostate. It helps shrink the cancer and increases the effectiveness of radiation therapy.

Is aggressive prostate cancer treatable?

Advanced prostate cancer is not “curable,” but there are many ways to treat it. Treatment can help slow advanced prostate cancer progression.

What stage is aggressive prostate cancer?

Stage 4 prostate cancer is cancer that begins in the prostate and spreads to nearby lymph nodes or to other areas of the body.

How serious is a radical prostatectomy surgery?

Radical prostatectomy has a low risk of serious complications. Death or serious disability caused by radical prostatectomy is extremely rare. Important nerves travel through the prostate on the way to the penis. Skilled surgeons can usually protect most of these nerves during radical prostatectomy.

What is the life expectancy for aggressive prostate cancer?

A decade ago, a man with metastatic prostate cancer would typically have a life expectancy of two to three years. Today, life expectancy for men with the same advanced disease is likely to be five to six years.

How long does it take aggressive prostate cancer to spread?

Prostate cancer is a cancer that develops in the prostate gland in men and it is one of the most common types of cancer. In some cases, it can take up to eight years to spread from the prostate to other parts of the body (metastasis), typically the bones. In other cases, it may be more aggressive.

What is the most aggressive prostate cancer?

Ductal prostate cancer is usually more aggressive than common prostate cancer, and it's more likely to come back after treatment. Although glandular epithelial cells produce PSA, men with ductal prostate cancer often have normal PSA levels.

What does aggressive prostate cancer mean?

High-risk prostate cancer is aggressive, meaning it is likely to spread quickly outside the prostate. Understanding the risk level of your cancer will help your doctor advise you about possible treatments. Your doctor will look at key "markers" for aggressive cancer, as well as the "stage" of your specific cancer.

What causes aggressive prostate cancer?

Like all types of cancer, the exact cause of prostate cancer isn't easy to determine. In many cases, multiple factors may be involved, including genetics and exposure to environmental toxins, like certain chemicals or radiation.

Is prostatectomy a major surgery?

A radical prostatectomy, which removes the entire prostate gland as well as some surrounding tissue, takes a few hours to complete. Here are three things you can expect after your prostate is removed. Prostate removal is major surgery, so expect some soreness and pain.

What is the most common problem after prostatectomy?

Stress incontinence is the most common type after prostate surgery. It's usually caused by problems with the valve that keeps urine in the bladder (the bladder sphincter). Prostate cancer treatments can damage this valve or the nerves that keep the valve working.

How long can you live after radical prostatectomy?

Based on the natural history of localized prostate cancer, the life expectancy (LE) of men treated with either radical prostatectomy (RP) or definitive external-beam radiotherapy (EBRT) should exceed 10 years.

Is aggressive prostate cancer serious?

High-risk prostate cancer is aggressive, meaning it is likely to spread quickly outside the prostate. Understanding the risk level of your cancer will help your doctor advise you about possible treatments. Your doctor will look at key "markers" for aggressive cancer, as well as the "stage" of your specific cancer.

What is the most aggressive type of prostate cancer?

Ductal prostate cancer is usually more aggressive than common prostate cancer, and it's more likely to come back after treatment. Although glandular epithelial cells produce PSA, men with ductal prostate cancer often have normal PSA levels.

Can aggressive cancer be cured?

While advanced cancers cannot be cured, there are still things that can be done to help you feel as good as possible for as long as possible. This care, aimed at relieving suffering and improving the quality of life, is called palliative care. Palliative care focuses on the patient and family rather than the disease.

What percent of prostate cancer is aggressive?

Yet in 10 to 15 percent of cases, the cancer is aggressive and advances beyond the prostate, sometimes turning lethal.

What are the treatments for prostate cancer?

There are 2 other therapies that may be given in conjunction with surgery, based on your pathology report after the surgery: 1 Radiation therapy is recommended in some men with high-risk prostate cancer who have cancer that has penetrated through the prostate capsule (layer of connective tissue around the prostate) and/or who have positive margins after surgery. Research has shown that recurrence rates drop by approximately 50% in men with a positive margin or T3 disease if radiation is given after surgery. You should discuss with your doctor the risks and benefits of radiation therapy. Another strategy is to use radiation only if PSA levels rise; this is referred to as salvage radiation. Genomic tests (eg, Decipher, GenomeDx) have been developed that may help you and your doctor decide if you would benefit from adjuvant radiation therapy versus waiting to see if the PSA rises 2 Hormone therapy may be recommended for men who have cancer found in their lymph nodes at the time of surgery; for these men, hormone therapy following surgery has been shown to help patients live longer. Multiple clinical trials have not demonstrated a significant benefit to using hormone therapy before surgery, however.

What is the procedure to remove the prostate gland?

Radical Prostatectomy. Removing the entire prostate gland through surgery, known as a radical prostatectomy, is a common option for men whose cancer has not spread. For men with advanced or recurrent disease, other surgical procedures may be chosen, such as removal of lymph nodes, which are initial landing spots for the spread of prostate cancer.

Where is the prostate removed?

Open radical prostatectomy is the classical way of surgically removing the prostate. In this procedure, the surgeon makes an incision in the lower abdomen in order to remove the prostate. The prostate may also be removed through the perineum, the area between the scrotum and the anus, although this technique is uncommon.

Does radiation help with prostate cancer?

Radiation therapy is recommended in some men with high-risk prostate cancer who have cancer that has penetrated through the prostate capsule (layer of connective tissue around the prostate) and/or who have positive margins after surgery.

Can you use radiation if your PSA is high?

Another strategy is to use radiation only if PSA levels rise; this is referred to as salvage radiation. Genomic tests (eg, Decipher, GenomeDx) have been developed that may help you and your doctor decide if you would benefit from adjuvant radiation therapy versus waiting to see if the PSA rises.

Can men have hormone therapy before surgery?

Hormone therapy may be recommended for men who have cancer found in their lymph nodes at the time of surgery; for these men, hormone therapy following surgery has been shown to help patients live longer. Multiple clinical trials have not demonstrated a significant benefit to using hormone therapy before surgery, however.

Overview

Radical prostatectomy is a surgical treatment for prostate cancer. This procedure can cure prostate cancer that hasn’t spread outside your prostate gland.

Procedure Details

Before radical prostatectomy, your provider will ask you about your health history. You’ll also need to tell your provider what drugs and vitamins you take. You may need to stop taking some of your medications a few days before your surgery, especially drugs that cause blood thinning.

Recovery and Outlook

The likelihood of recurrence-free survival depends on the pathologic stage. You’ll need to have regular follow-up appointments with your healthcare provider to make sure the cancer has not returned.

When to Call the Doctor

Talk to your healthcare provider if you have any of these symptoms after your surgery:

What is radical prostatectomy?

A radical prostatectomy is a surgical procedure that removes the prostate gland and attached seminal vesicles. Lymph nodes near the prostate can be removed at the same time. Radical prostatectomy is one treatment option for men with localized prostate cancer.

How is the prostate removed?

Perineal. In this procedure, the prostate is removed through an incision in the skin between the scrotum and anus. The lymph nodes can't be removed through this incision. If the lymph nodes need to be examined, removal can be done through a small abdominal incision or by a laparoscopic procedure.

What is the procedure to remove prostate and lymph nodes?

Retropubic. In this procedure, the surgeon uses an incision in the lower abdomen to remove the prostate and the lymph nodes for examination. This procedure allows for a nerve-sparing approach, which can lower but not totally eliminate the risk of impotence following surgery.

What is the procedure called when a prostate gland is removed?

This is done to determine if the prostate cancer has spread to the lymph nodes. The procedure is called pelvic lymph node dissection.

What tests are done before prostate surgery?

These tests include blood tests, transrectal ultrasound and a prostate biopsy. Selected patients may receive a bone scan and a computed tomography (CT) or magnetic resonance imaging (MRI) scan of the abdomen and pelvis.

How many incisions are needed for prostate removal?

In this recently developed procedure, the prostate is removed in a fashion similar to a retropubic prostatectomy, but the procedure is performed through five very small (less than 1.0 cm) inci sions using lighted, magnified scopes and cameras.

Can you get radiation after prostate surgery?

The serum prostate-specific antigen (PSA) level should be undetectable, and recurrence of cancer is relatively easy to detect because of this. Radiation can be given after surgery, if necessary, with a low risk of any additional side effects.

What is radical prostatectomy?

A radical prostatectomy is a surgery used to treat prostate cancer. If you’ve been diagnosed with prostate cancer, your doctor will discuss different options for treatment. If your cancer is only inside the prostate gland and hasn’t spread to surrounding tissue, your doctor may recommend a radical prostatectomy.

Why is a prostate surgery called a radical prostatectomy?

The surgery is called a “radical” prostatectomy because the entire prostate gland is removed. In other prostate surgeries, such as a “simple” prostatectomy, only part of the gland is removed.

What is the best treatment for prostate cancer?

A radical prostatectomy might be your best treatment option if your tumor is inside your prostate gland and hasn’t invaded surrounding areas. This treatment is done to remove the cancer before it can spread to other parts of your body. The entire prostate is removed.

What type of anesthesia is used for prostatectomy?

Epidural or spinal anesthesia can also be used. With this type of anesthesia, you can’t feel anything below your waist. Sometimes, both types of anesthesia are used to control potential bleeding and to provide the best pain management. The three main types of radical prostatectomy surgery are: 1.

What is pelvic lymph node dissection?

This procedure is called pelvic lymph node dissection. Lymph nodes are fluid-filled sacs that are part of your immune system. Your doctor will examine your pelvic lymph nodes to determine whether your prostate cancer has spread, or metastasized, to them.

How is the prostate removed?

The prostate is removed through one of the holes with a small bag. This type of surgery often involves less pain afterward, requiring less recovery time. Using the “nerve-sparing” approach with this method may not be as successful as with the “open” type of surgery. 3. Open radical perineal prostatectomy.

How to remove prostate from pubic bone?

1. Open radical retropubic prostatectomy. In this surgery, the doctor makes a cut just below your belly button down to your pubic bone. The surgeon moves aside muscles and organs to remove the prostate, vas deferens, and seminal vesicles.

What is the first line of treatment for prostate cancer?

If your medical team determines that your prostate cancer has become aggressive and needs to be treated, an operation called radical prostatectomy — removal of the prostate — is typically the first-line treatment. This surgery removes the prostate gland and surrounding tissues such as the seminal vesicles and sometimes nearby lymph nodes.

How long can you lift after pelvic surgery?

Restrictions are similar to other pelvic surgery: no lifting more than five pounds for six weeks. No straining to lift for six months. Men can resume sex and activities such as walking or swimming immediately. More strenuous exercise should wait at least six weeks.

Is prostate cancer aggressive?

Prostate cancer grows slowly, even when aggressive. Prostate cancer is neither lung cancer nor pancreatic cancer nor leukemia. You have time to stop, get educated and arrive at a treatment decision that’s right for you.”. Featured Expert. Image.

Can radiation be used after prostatectomy?

However, Dr. Mohler cautions against beginning radiation treatment too soon after radical prostatectomy. “You need to be fully healed and have regained urinary control, because radiation can cause scarring that might hamper that,” he says.

What happens if you have a radical prostatectomy?

During radical prostatectomy, the removed prostate is examined under a microscope to see if prostate cancer has reached the edge of the prostate. If so, the prostate cancer has probably spread. In these cases, further treatments may be needed.

What is the difference between radical prostatectomy and laparoscopic prostatectomy?

In laparoscopic prostatectomy, surgeons make several small incisions across the belly. Surgical tools and a camera are inserted through the incisions, and radical prostatectomy is performed from outside the body. The surgeon views the entire operation on a video screen.

What is the procedure to remove the prostate gland?

Prostate Cancer: Radical Prostatectomy. Radical prostatectomy is an operation to remove the prostate gland and tissues surrounding it. This usually includes the seminal vesicles and some nearby lymph nodes. Radical prostatectomy can cure prostate cancer in men whose cancer is limited to the prostate.

How long does it take for prostate cancer to return after a radical prostatectomy?

Pain after radical prostatectomy can generally be controlled with prescription pain medicines. It can take weeks or months for urinary and sexual function to return to their maximum levels. After radical prostatectomy, regular follow-up is essential to make sure prostate cancer does not return.

What to do if prostate cancer has not spread?

If it appears that the prostate cancer has not spread, a surgeon (urologist) may first offer other options besides surgery. These can include radiation therapy, hormone therapy, or simply observing the prostate cancer over time, since many prostate cancers grow slowly.

Where is the prostate gland located?

The prostate gland lies just under the bladder, in front of the rectum. Surgeons choose from two different approaches to reach and remove the prostate during a radical prostatectomy. One is a traditional approach known as open prostatectomy. The other, more recent approach is minimally invasive.

How long do you stay in the hospital after a prostatectomy?

Most men stay in the hospital for one to three days after radical prostatectomy. A urinary catheter is inserted during the surgery, and some men may need to wear the catheter home for a few days to a few weeks. Another catheter inserted through the skin also may need to stay in place for a few days after returning home.

Urination Problems

Urinary incontinence, or the loss of bladder control, sometimes happens following surgery in this delicate part of the body. It can be caused by increased pressure on the bladder, muscle spasms, or damage to the sphincter muscle, which controls bladder flow.

Erectile Dysfunction (ED)

Even when surgeons use the most-advanced techniques, erectile dysfunction can occur. Also referred to as impotence, it means that you’re unable to get or maintain an erection. This happens if prostate surgery disrupts the nerves close to the prostate that control blood flow to the penis.

Why do men need radical prostatectomy?

Age of the patient — Radical prostatectomy is offered mostly to men under 70 years of age because they are more likely to live longer and be able to survive any long term effects of the disease. 2. The natural progression of the disease — Slow progression of a non-aggressive tumor does not lend itself to surgery.

What is the treatment for prostate cancer?

On the other hand, radiation therapy, also known as radiotherapy, is used in the treatment of almost all cancers, including prostate cancer. It involves the use of high doses of radiation to kill cancer cells or to slow their development by destroying their DNA.

What is radiation therapy for prostate cancer?

Introduction. Radical prostatectomy and radiation therapy are both cancer treatment methods. Radical prostatectomy is specific to prostate cancer and involves the surgical removal of the prostate, either alone or with other surrounding tissues such as the seminal vesicles and some lymph nodes.

How long does it take to remove a prostate?

It takes just a few hours to completely remove the affected prostate and the patient is likely to recover fully, albeit gradually and with the monitoring of a urologist. The main disadvantage is that it is appropriate only where the cancer has not spread to other organs outside the prostate.

How to make the right choice in urology?

In order to make the right choice, make a point of consulting a qualified urologist. Reading material on the subject should also be helpful, and sites such as the one operated by the Advanced Urology Institute should be a good place to start. For more information, visit the Advanced Urology Institute website.

What is radical prostatectomy?

radical prostatectomy is a surgical procedure whereby the prostate gland is removed. Lymph nodes near the prostate can be removed at the same time. Radical prostatectomy is one option for men with clinically localized prostate cancer. Potential advantages include the following: 1) removal of the prostate and analysis by a pathologist allows accurate assessment of cancer aggressiveness (stage and grade); 2) follow-up after surgery is straightforward: the serum PSA (prostate specific antigen) level should be undetectable, and recurrence of cancer is relatively easy to detect because of this; 3) radiation can be given after surgery, if necessary, with a relatively low risk of any additional side effects; and 4) surgery appears to be associated with a very limited risk of late (i.e. beyond 5 years) local recurrence if careful and sensitive PSA testing is performed. Patients who are in good health, have a long life expectancy and have cancers which appear to be confined to the prostate gland are candidates for radical prostatectomy. Some men with more advanced cancers may benefit from the procedure as well. The procedure is associated with certain side effects, although major complications are very rare. Many men may be candidates for a “nerve-sparing” radical prostatectomy whereby sexual function may be preserved.

What is the best medication for prostate surgery?

After surgery you will receive an anti-inflammatory medication called ketorolac (Toradol), which is similar to ibuprofen (Motrin), unless you have a history of stomach ulcers or kidney dysfunction. For some men, this is sufficient. If you do have pain, you may receive oral narcotic tablets, usually Vicodin (hydrocodone and acetominophen), and if your pain is more severe you can receive intravenous hydromorphone (Dilaudid), which is similar to morphine. Narcotics, both oral and intravenous, can cause nausea and drowsiness and tend to slow bowel function, so you should use only as much of these medications as you need. On the other hand, it is important to make sure your pain is controlled enough not just to lay in bed, but also to take deep breaths, cough and walk. It is easier to stay ahead of postoperative pain than to try to catch up once in severe pain, so make sure you ask for pain medicine early if needed. The same guidelines apply when you go home with medication (usually Vicodin) for pain. If you feel you are not getting adequate pain relief, please feel free to discuss this with your nurse or doctor. Each person’s experience of pain is different, and although we may not be able to completely eliminate all of your discomfort, we want you to be as comfortable as possible after your surgery.

What to do if you have a spasm after surgery?

During the time that you are taking them, be sure to increase your fluid intake (at least eight glasses of water a day), take stool softeners, and eat lots of roughage (whole grains, fruit and vegetables). Use laxatives only as a last resort. Diarrhea may also occur in the first few days after surgery as your bowel function returns to normal. This usually fairly mild; if it is severe or not improving, contact your doctor.

Why do you remove lymph nodes from prostate?

When prostate cancer spreads (metastasizes) it often does so into lymph nodes in the area of the prostate. For this reason, the lymph nodes close to the prostate may be removed to check for tumor spread. The lymph nodes may be removed during either open or laparoscopic (robot-assisted) surgery and will be performed at the same time as prostate removal using the same incision(s). As mentioned, lymph node dissection is not necessary in all patients. Only those at moderate or high-risk of lymph node metastases need undergo the procedure.

How to get rid of urinary leakage after catheter removal?

Your doctor or nurse will teach you exercises which you can do to strengthen your sphincter muscle. These are called Kegel exercises and they can be done anytime: when lying down, sitting, standing or walking. You should do 200 repetitions of five second Kegel exercises per day. These exercises will tend to decrease the amount of time it takes you to recover continence.

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Are There Different Types of Radical Prostatectomy?

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There are several methods of radical prostatectomy: 1. Radical prostatectomy with retropubic (suprapubic) approach. This is the most common surgical approach used by urologists (doctors who specialize in diseases and surgery of the urinary tract). If there's reason to believe the cancer has spread to the lymph nodes, the d…
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Risks of The Procedure

  • As with any surgical procedure, certain complications can occur. Somepossible complications of both the retropubic and perineal approaches to RPmay include: 1. Urinary incontinence . Incontinence involves uncontrollable, involuntary leaking of urine, which may improve over time, even up to a year after surgery. This symptom may be worse if you're older than age 70 when th…
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Before The Procedure

  • Some things you can expect before the procedure include: 1. Your doctor will explain the procedure to you and offer you the opportunity to ask any questions you might have about the procedure. 2. You'll be asked to sign a consent form that gives your permission to do the procedure. Read the form carefully and ask questions if something isn't clear. 3. In addition to a …
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During The Procedure

  • Radical prostatectomy requires a stay in the hospital. Procedures may varydepending on your condition and your doctor's practices. Generally, a radical prostatectomy (retropubic or perineal approach)follows this process: 1. You'll be asked to remove any jewelry or other objects that may interfere with the procedure. 2. You'll be asked to remove your clothing and will be given a gown …
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After The Procedure

  • After the procedure, you may be taken to the recovery room to be closelymonitored. You'll be connected to monitors that will constantly displayyour heart beat (electrocardiogram—ECG or EKG) tracing, blood pressure,other pressure readings, breathing rate, and your oxygen level. You may receive pain medication as needed, either by a nurse, or byadministering it yourself through …
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