What is pseudochromhidrosis and what causes it?
Pseudochromhidrosis: This results when dyes, chemicals, or pigment-producing bacteria mix with colorless eccrine sweat to form colored sweat. Chromhidrosis can occur at nearly any age, but it usually becomes noticeable after puberty, when the apocrine glands begin secreting fluid.
What is the best treatment for Chromhidrosis?
The best treatment depends on the type of chromhidrosis: Treatment for this type of chromhidrosis either aims to reduce the amount of sweat or to induce the sweat and empty the glands. The latter approach can stop the sweat from happening for up to 3 days at a time.
Does pseudochromhidrosis recur on restarting only the proton pump inhibitor?
The pseudochromhidrosis resolved on stopping both medications and did not recur on restarting only the proton pump inhibitor. 2-Pyridinylmethylsulfinylbenzimidazoles / pharmacology
What is progressive pseudochromhidrosis (PRP)?
Pseudochromhidrosis is an extremely rare pathology of the eccrine sweat glands. Patients produce colorless sweat that subsequently becomes colored when being in contact with various external compounds, which leads to black, blue, pink, brown, yellow, or red discoloration of the skin.
What is Pseudochromhidrosis?
Pseudochromhidrosis is production of colorless sweat, which becomes colored when it reaches the skin and comes in contact with extrinsic agents such as chromogenic bacterial products, fungi, dyes, paint, and colored foods.
Can you cure chromhidrosis?
Apocrine chromhidrosis has no fully satisfactory cure or treatment. Patients can manually or pharmacologically empty the glands to achieve a symptom-free period of about 48-72 hours or until the glands replenish the pigment. BOTOX® injections have been attempted in 5 cases of chromhidrosis, with mixed results.
How does chromhidrosis happen?
Chromhidrosis is a rare condition characterized by the secretion of colored sweat. It is caused by the deposition of lipofuscin in the sweat glands. Cases of red, blue, green, yellow, pink, and black sweat have been reported. Usually, chromhidrosis affects the apocrine glands, mainly on the face and underarms.
What drugs cause chromhidrosis?
Eccrine chromhidrosis is due to water-soluble coloured dyes and other chemicals being excreted in the eccrine sweat. Examples include: Ingestion of medications, metals, and dyes including tartrazine-coated bisacodyl laxatives, quinine, rifampicin, clofazimine, methylene blue, mercury, and copper.
Is chromhidrosis serious?
Chromhidrosis is a rare chronic condition that causes sweat to turn black, blue, green, yellow, or brown. The coloration may be barely noticeable and restricted to a few locations or more widespread. Chromhidrosis is harmless, but it can cause embarrassment or distress that may lead to depression or anxiety.
How can you prevent chromhidrosis?
According to the medical journal Pediatrics, chromhidrosis can be treated with topical capsaicin cream 0.025% (applied to the affected skin 1-2 times per day). Others have noted that Botox injections can treat chromhidrosis.
How do you test for chromhidrosis?
Multiple staining modalities targeted at lipofuscin pigments can give histological clues to the diagnosis of chromhidrosis. Under H&E, increased lipofuscin granules may be observed in the apical side of secretory cells in the apocrine glands.
What is eccrine chromhidrosis?
Eccrine chromhidrosis is a rare condition in which water-soluble pigments from certain dyes or drugs are excreted via the eccrine sweat glands-in our case, the bile components.
How do you stop yellow sweat?
Prevent yellow sweat stains by washing your clothes with extra care. To avoid yellow sweat stains from forming on your clothes: Try pre-treating dirty clothing with laundry detergent or color-safe bleach. Apply a stain-releasing spot cleaner to any areas of your clothes prone to stains, such as your underarms.
Why do I have blue sweat?
Signs and symptoms of chromhidrosis Normally, sweat is a clear, salty fluid, but for people with chromhidrosis, sweat may appear a vivid color such as: Yellow. Green. Blue.
Why my sweat leave yellow stains?
Your sweat consists of water, ammonia, urea, salts, and sugar, and on its own, is colourless and odourless. However, when your sweat reacts with chemicals such as active ingredients in your antiperspirant, laundry detergent, or bacteria, it can turn yellow and cause stubborn yellow stains.
Is there an over the counter medicine for excessive sweating?
There is no over-the-counter medicine for excessive sweating and, by law, over-the-counter antiperspirants can contain no more than 15% aluminum chloride. But most OTC antiperspirants use less effective formulations and contain no aluminum chloride at all.
Presentation
Pseudochromhidrosis is a rare phenomenon in clinical practice, with only a handful of cases described in the literature so far [1] [2] [3]. The coloration of the skin seen in these individuals stems from the initial production of uncolored sweat that interacts with various substances present on the skin [1] [4] [5].
Workup
Because of the rare occurrence of pseudochromhidrosis, clinicians will unlikely encounter this disorder. For this reason, the physician must conduct a thorough investigation in the presence of skin discoloration.
Treatment
This article provides a literature review of the various etiology, investigation, treatment, and prognosis. [ncbi.nlm.nih.gov]
Prognosis
This article provides a literature review of the various etiology, investigation, treatment, and prognosis. [ncbi.nlm.nih.gov]
Etiology
This article provides a literature review of the various etiology, investigation, treatment, and prognosis. [ncbi.nlm.nih.gov]
Epidemiology
Patient Population: Prevalence and Epidemiology Knee // Shoulder & Elbow // Hip // Spine // Foot & Ankle // Hand & Wrist Fragility Fractures: Diagnosis and Treatment Shoulder & Elbow The Characteristics of Surgeons Performing Total Shoulder Arthroplasty [mdedge.com]
Pathophysiology
Although the presentations of apocrine and eccrine chromhidrosis are similar, the pathophysiology is quite different. [idoj.in]
What are the symptoms of chromhidrosis?
These symptoms can include: a general feeling of hopelessness, worthlessness, helplessness, guilt or pessimism. a persistent anxious, sad, or “empty” mood.
How long does apocrine chromhidrosis last?
The latter approach can stop the sweat from happening for up to 3 days. Trusted Source.
Why does chromhidrosis discolor?
In people with eccrine chromhidrosis, the discoloration usually happens because the person has ingested. Trusted Source. : water-soluble dyes. heavy metals, such as copper. certain food colorings or flavorings. certain medications, such as bisacodyl, a laxative, when it is coated in tartrazine, a yellow dye.
What is the defining symptom#N#Trusted Source#N#of Chromhidrosis?
The defining symptom#N#Trusted Source#N#of chromhidrosis is the production of colored sweat. The color may only affect sweat in certain areas or sweat all over the body. The color and the vividness of the shade can vary from person to person.
Is chromhidrosis related to sex?
There seems to be no association between chromhidrosis and sex, geographic location, season, or weather, though it may be more likely to develop in people of African descent. Although the condition is chronic, the discoloration of sweat may decrease. Trusted Source.
Can chromhidrosis cause anxiety?
The coloration may be barely noticeable and restricted to a few locations or more widespread. Chromhidrosis is harmless, but it can cause embarrassment or distress that may lead to depression or anxiety. If sweat changes color, contact a doctor, who may rule out other causes before diagnosing chromhidrosis.
