what is phenol treatment

What is phenol used for?

• Phenol Injection. Phenol can be injected into your muscles to treat a condition known as muscle spasticity. ...
• Chemical matrixectomy. Phenol is commonly used in surgeries for ingrown toenails. ...
• Vaccine preservative. ...
• Sore throat spray. ...
• Oral analgesics. ...
• Phenol derivatives. ...
• Phenol liquid. ...
• Soap and antiseptic. ...

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What are the dangers of phenol?

• Diethylene glycol found in window cleaners depresses the nervous system.
• Formaldehyde found in spray and wick deodorizers is a respiratory irritant and suspected carcinogen.
• Petroleum solvents in floor cleaners damage mucous membranes.
• Perchloroethylene, a spot remover, causes liver and kidney damage.

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What is phenol used for in medical practices?

What is phenol used for?

• Phenol Injection. Phenol can be injected into your muscles to treat a condition known as muscle spasticity. ...
• Chemical matrixectomy. Phenol is commonly used in surgeries for ingrown toenails. ...
• Vaccine preservative. ...
• Sore throat spray. ...
• Oral analgesics. ...
• Phenol derivatives. ...
• Phenol liquid. ...
• Soap and antiseptic. ...

Why does phenol have a low pKa?

Why does phenol have a low pKa? Nitro groups are very powerful electron-withdrawing groups. The phenol derivative picric acid has a pKa of 0.25, lower than that of trifluoroacetic acid. Use a resonance argument to explain why picric acid has such a low pKa. Notice that the methoxy group increases the pKa of the phenol group - it makes it less ...

What products contain phenol?

What products contain phenol? Phenol is a very common chemical and is regularly found in the following common products : air fresheners, aftershave, bronchial mists, chloroseptic throat spray, deodorants, feminine powders & sprays, hair spray, decongestants, mouthwash, aspirin, solvents, acne medications, antiseptics, calamine lotions, cleaning

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What is phenol in plants?

What is phenol derivative?

How long can you use phenol for throat pain?

Is BHT a preservative?

Is phenol bad for you?

Is phenol a toxic substance?

Can you eat phenol?

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About this website

What is phenol used to treat?

Descriptions. Phenol is used to relieve pain and irritation caused by sore throat, sore mouth, or canker sores. This medicine is available without a prescription; however, your doctor may have special instructions on the proper use and dose for your medical problem.

What does phenol do to your skin?

If phenol is left on the skin, it will penetrate rapidly and lead to cell death and gangrene. If more than 60 square inches of skin are affected, there is risk of imminent death. Phenol appears to have local anesthetic properties and can cause extensive damage before pain is felt.

Is phenol an anesthetic?

No pain or discomfort was reported by 89.5% and 94.7% had no bleeding. There was no vertigo in all the cases that completed the procedures. Conclusion. This preliminary result shows that the use of phenol as a topical local anesthetic is simple, safe, and effective especially in resource-limited environments.

Why is phenol no longer used?

EPA has classified phenol as a Group D, not classifiable as to human carcinogenicity. delayed permanent adverse health effects or prevent escape from the environment. delayed permanent adverse health effects or prevent escape from the environment.

What are the side effects of phenol?

Exposure to phenol may cause irritation to the skin, eyes, nose, throat, and nervous system. Some symptoms of exposure to phenol are weight loss, weakness, exhaustion, muscle aches, and pain. Severe exposure can cause liver and/or kidney damage, skin burns, tremor, convulsions, and twitching.

Is phenol safe on skin?

Overview. The major hazard of phenol is its ability to penetrate the skin rapidly, causing severe burns. Toxic and even fatal amounts of phenol can be absorbed through relatively small areas of skin. Due to its local anesthetizing properties, skin burns may be painless.

How long does phenol nerve block last?

Phenol block injections are often performed under sedation or general anesthesia, but in some instances it may be done as an outpatient procedure. A phenol block usually lasts four to 12 months.

Is phenol injection painful?

Because phenol has immediate local anesthetic effects, injection is typically painless.

How long does it take a phenol injection to work?

Phenol Injection Phenol typically takes effect immediately and lasts four to 12 months. This injection is placed directly on a nerve—which requires finding the nerves to be blocked.

Can I buy phenol?

You can buy over-the-counter phenol spray almost anywhere. The most common brand is Chloraseptic. It contains about 1.4 percent phenol. Phenol spray is safe to use at the recommend dose for a short time.

Is phenol cancerous?

Cancer There is no evidence that phenol causes cancer in humans. The International Agency for Research on Cancer (IARC) and the EPA determined that phenol is not classifiable as to human carcinogenicity.

Is phenol a poison?

Phenol is a protoplasmic poison with myriad effects. Its dual hydrophilic and lipophilic properties allow it to easily break through cellular membranes, denaturing proteins along the way, ultimately leading to cell death and necrosis. A caustic effect resulting in coagulation necrosis can also occur.

What is a phenol peel?

A phenol acid peel is the most aggressive, deep chemical peel available. This skin resurfacing procedure can be extremely effective at treating sig...

What are the pros and cons of a phenol peel?

ProsA phenol chemical peel can improve the quality of your skin in just a single treatment, yielding dramatic results. You can expect results to la...

How much does a phenol peel cost?

The price you pay will depend on your provider’s level of experience, their practice location, whether you have IV sedation, and other details of y...

How does a phenol peel work?

Phenol (also known as carbolic acid) exfoliates so deeply that it removes the outer layers of skin, eradicating damaged skin cells, promoting colla...

What happens during a phenol peel procedure?

First, you'll be given a sedative or IV anesthesia as well as a topical anesthetic cream, to fully numb your face and keep you relaxed. After thoro...

How long does recovery take?

Most people need two full weeks of downtime after a phenol peel.Immediately after your treatment, you will look like you have a severe sunburn. You...

Are phenol peels dangerous?

When administered by an experienced plastic surgeon or dermatologist and for the right candidate (someone with a fair skin tone, a low risk of hype...

What Is Phenol Used For? - MedicineNet

Phenol is a widely used chemical solvent used in numerous places, including chemistry, biology and medical laboratories. It is extremely toxic. It is found in small amounts in certain products that are used as an anesthetic.

Glycerin and phenol intolerance or allergy

Reviewed: February 24, 2020 12/18/2014 We have two patients that are allergy to phenol and React to glycerin. They also have food allergies to beef, so bovine products are out.

What is phenol peel?

What is a phenol peel? A phenol acid peel is the most aggressive, deep chemical peel available. This skin resurfacing procedure can be extremely effective at treating signs of severe sun damage, including deep wrinkles, fine lines, sunspots or freckles, and discoloration ( hyperpigmentation ), as well as acne scars, precancerous growths, ...

Can phenol peels be used on the neck?

Because of its strength, a phenol peel should be administered only by an experienced , board-certified plastic surgeon or dermatologist. It can be applied solely to your face; the skin on your neck is too delicate.

What is phenol topical?

Phenol topical is used on the skin to help protect skin from infection in minor cuts, scrapes, or burns.

Warnings

Use exactly as directed on the label, or as prescribed by your doctor.

How should I use phenol topical?

Use exactly as directed on the label, or as prescribed by your doctor.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

An overdose of phenol topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

Phenol topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

What other drugs will affect phenol topical?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What are the symptoms of phenol?

Nausea, vomiting, abdominal pain, and diarrhea are common symptoms after exposure to phenol by any route. Ingestion of phenol can also cause severe corrosive injury to the mouth, throat, esophagus, and stomach, with bleeding, perforation, scarring, or stricture formation as potential sequelae.

What is phenol in air?

At room temperature, phenol is a translucent, colorless, crystalline mass, white powder, or thick, syrupy liquid. The crystals are hygroscopic and turn pink to red in air. When pure, phenol has a sweet, tar-like odor that is readily detected at low concentrations (0.05 ppm in air). Phenol is soluble in alcohol, glycerol, petroleum, and, to a lesser extent, water. Phenol is designated as "Poison B" by the Department of Transportation (DOT), but no special containers are required due to its modest fire hazard and low reactivity.

What is phenol poisoning?

As a corrosive substance, phenol denatures proteins and generally acts as a protoplasmic poison. Phenol may also cause peripheral nerve damage (i.e., demyelination of axons). Systemic poisoning can occur after inhalation, skin contact, eye contact, or ingestion. Typically, transient CNS excitation occurs, then profound CNS depression ensues rapidly. Damage to the nervous system is the primary cause of death from phenol poisoning. However, damage to other organ systems (e.g., acid-base imbalance and acute kidney failure) may complicate the condition. Symptoms may be delayed for up to 18 hours after exposure.

What tests are used to determine if phenol is toxic?

Depending on the initial evaluation, additional studies for patients exposed to phenol include ECG monitoring and kidney-function tests. Laboratory tests to determine hemolysis include peripheral blood smear, urinalysis, and plasma free hemoglobin and haptoglobin analyses. Chest radiography and pulse oximetry (or ABG measurements) are also recommended for severe inhalation exposure or if pulmonary aspiration is suspected.

How much phenol is fatal?

Accidental and intentional ingestions of phenol have been reported. As little as 50 to 500 mg has been fatal in infants. Deaths in adults have resulted after ingestions of 1 to 32 g.

What happens if you put phenol on your skin?

When phenol is applied directly to the skin, a white covering of precipitated protein form s. This soon turns red and eventually sloughs, leaving the surface stained slightly brown. If phenol is left on the skin, it will penetrate rapidly and lead to cell death and gangrene. If more than 60 square inches of skin are affected, there is risk of imminent death. Phenol appears to have local anesthetic properties and can cause extensive damage before pain is felt.

How long can you stay asymptomatic after phenol?

Patients who have mild exposure and remain asymptomatic for 2 to 4 hours may be discharged with instructions to seek medical care promptly if symptoms develop (see the Phenol-Patient Information Sheet below).

What is phenol used for?

Phenol in low concentrations is used as a disinfectant in household cleaners and mouthwash. Phenol used as a slimicide (a chemical toxic to bacteria and fungi characteristic of aqueous slimes) is a type of disinfectant. The largest single use of phenol is as an intermediate in the production of phenolic resins.

Why is phenol used in water?

Phenol has been used traditionally for sterilization of surgical areas before performing any procedure. Small amounts of phenol in water have been injected into nerve tissue to lessen the pain associated with certain nerve disorders. Phenol destroys the outer layers of the skin if allowed to remain in contact with the skin.

How to get rid of phenol eye?

Irrigate the affected eye with copious amounts of running water and the immediately to to the hospital. Wash your hands with plenty of water before and after handline phenols. Clean the affected area before use. Make sure to dry the area well. Put a thin layer on the affected skin and rub gently .

What is the smell of phenol?

Phenol (also known as carbolic acid) is an aromatic organic compound, usually in the form of colorless or white crystals. It has a sickly sweet smell and sharp burning taste. Phenol is part of coal tar and is formed during the natural decomposition of organic materials.

Can you use phenol in the nose?

Use phenol topical solution as directed by your doctor. Follow all instructions closely. Do not use phenol topical solution orally. Keep it away from your nose and eyes (may burn ).

Can phenol cause burns?

Low-level exposure from the correct use of products that contain phenol would not be expected to cause any adverse health effects. Exposure to high concentrations can result in serious health effects. High concentrations may cause irritation, burns and discoloration of the skin, mouth, throat, eyes and airways.

What to do if you are allergic to phenol?

If you are allergic to phenol topical solution; any part of phenol topical solution; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If a large area needs to be treated. This medicine may interact with other drugs or health problems.

Can you use phenol for longer than you were told by your doctor?

Do not use phenol topical solution for longer than you were told by your doctor. This medicine may stain fingernails, hair, and skin. Protect clothing and fabrics from staining. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding.

Can you take phenol twice at the same time?

If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not use 2 doses at the same time or extra doses.

Can you use phenol on your skin?

Follow all instructions closely. Do not take phenol topical solution by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn). Wash your hands before and after use. Do not wash your hands after use if putting this on your hand. Clean affected part before use. Make sure to dry well.

Can you take phenol with OTC?

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take phenol topic al solution with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Q: When is it used?

A: Liquid or crystallized phenol injections have been used for the treatment of mild to moderate pilonidal cysts and for patients seeking minimally invasive treatment options.

Q: How successful is it?

A: A one-time application has a 64.5% cure rate, and the rate of success approaches 95% with two or more applications.

Q: Is it painful?

A: Most patients report a mild burning sensation that subsides within a day, and requires no pain medications.

Q: How many treatments does it typically take?

A: The average number of treatments at different times is 2-3, though some patients will require more. Some patients only require 1 treatment.

Q: What is the treatment like?

A: Treatment will be in Dr. Kamrava’s medical office. The pit is widened with a sterile clamp, and the hair and debris that are in the cavity are cleared out. Dr. Kamrava will then place phenol crystals into the wound which will liquify and irritate the surrounding tissue, initiating the healing cycle.

Q: Complications to consider?

A: The most frequent adverse event is irritation to the surrounding skin by the phenol liquid that drains out. Typically irritation is well managed with the simple application of antibiotic ointments.

When was phenol discovered?

Phenol was discovered in 1834 by Friedlieb Ferdinand Runge, who extracted it (in impure form) from coal tar. Runge called phenol "Karbolsäure" (coal-oil-acid, carbolic acid). Coal tar remained the primary source until the development of the petrochemical industry. In 1841, the French chemist Auguste Laurent obtained phenol in pure form.

What is the chemical formula for phenol?

Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula C 6 H 5 OH. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group (−C 6 H 5) bonded to a hydroxy group (−OH). Mildly acidic, it requires careful handling because it can cause chemical burns .

What is the route analogous to cumene?

It is oxidized to a hydroperoxide, akin to the production of cumene hydroperoxide. Via the Hock rearrangement, cyclohexylbenzene hydroperoxide cleaves to give phenol and cyclohexanone. Cyclohexanone is an important precursor to some nylons.

What is reduced to benzene when distilled with zinc dust?

Phenol is reduced to benzene when it is distilled with zinc dust or when its vapour is passed over granules of zinc at 400 °C: C 6 H 5 OH + Zn → C 6 H 6 + ZnO. When phenol is reacted with diazomethane in the presence of boron trifluoride (BF 3 ), anisole is obtained as the main product and nitrogen gas as a byproduct.

How much phenol is in scotch?

Phenol is a measurable component in the aroma and taste of the distinctive Islay scotch whisky, generally ~30 ppm, but it can be over 160ppm in the malted barley used to produce whisky. This amount is different from and presumably higher than the amount in the distillate.

Why is phenol acidic?

Resonance structures of the phenoxide anion. One explanation for why phenol is more acidic than aliphatic compounds containing an -OH group is resonance stabilization of the phenoxide anion by the aromatic ring. In this way, the negative charge on oxygen is delocalized on to the ortho and para carbon atoms through the pi system.

Is phenol a corrosive substance?

Phenol and its vapors are corrosive to the eyes, the skin, and the respiratory tract. Its corrosive effect on skin and mucous membranes is due to a protein-degenerating effect. Repeated or prolonged skin contact with phenol may cause dermatitis, or even second and third-degree burns. Inhalation of phenol vapor may cause lung edema. The substance may cause harmful effects on the central nervous system and heart, resulting in dysrhythmia, seizures, and coma. The kidneys may be affected as well. Long-term or repeated exposure of the substance may have harmful effects on the liver and kidneys. There is no evidence that phenol causes cancer in humans. Besides its hydrophobic effects, another mechanism for the toxicity of phenol may be the formation of phenoxyl radicals.

What is phenol used for?

Phenol is a common chemical used for activities such as tissue preservation and DNA/RNA extraction. Phenol can be a component in a commercial reagent (e.g. QIAzol, TRIzol) or prepared as part of a mixture in the laboratory (e.g. chloroform: phenol). Because phenol solutions are an integral part of routine life science applications, their hazards may be taken for granted. Make no mistake about it, however. Phenol can be very dangerous and the hazards are not just those of a typical corrosive.

How to get rid of phenol in hands?

Put on safety glasses and silver shield gloves (but don’t put on the gloves if you are treating yourself and your hands are contaminated with phenol). Open up a few packages of gauze pads. Pour polyethylene glycol liberally on to one of the gauze pads. Gently wipe off excessive phenol on exposed area.

What gloves are good for phenol?

For working with phenol at concentrations >70%, butyl rubber, Viton, Barrier and Silver Shield gloves provide good resistance. Neoprene and polyvinyl alcohol are suitable for short term work (resistance to breakthrough within 1-4 hours) but should be thicker than 0.3 mm (11.8 mil).

How to reduce phenol uptake?

A high-density shower is preferable to reduce phenol uptake. Lesser amounts of water will merely dilute the phenol and expand the area of exposure. If possible, use PEG after the initial decontamination. Otherwise, the victim should stay in the shower until the emergency responders arrive to provide assistance.

What is the threshold concentration of phenol?

The threshold concentration of human skin damage from phenol is 1.5%. It can cause permanent eye injury, blindness and scarring. Recommendations are that laboratories working with phenol use polyethylene glycol 300 or 400 (PEG-300 or PEG-400), rather than water, for immediate first aid treatment of dermal exposures.

Where to put phenol first aid kit?

Phenol First Aid Kit. Laboratories that use phenol are advised to assemble a kit for first aid treatment of dermal exposure. The kit should be located in a visible area where the phenol work is being done (for instance, in the fume hood), or nearby with the location clearly posted.

What happens if phenol is left on the skin?

If phenol is left on the skin, it will penetrate rapidly and lead to cell death and gangrene.

What is phenol in plants?

Plant-based compounds containing phenol are known to be antioxidants . This means that they can stop the reaction of free radicals with other molecules in your body, preventing damage to your DNA as well as long-term health effects.

What is phenol derivative?

Phenol derivatives. Phenol-derived compounds have a variety of uses, including: Chemical peels. Phenol in trichloroacetic acid is used to penetrate through layers of skin to get rid of old or damaged skin. Food and cosmetic preservatives.

How long can you use phenol for throat pain?

But throat sprays and antiseptic liquids shouldn’t be used for more than a couple days at a time. And if you’re having symptoms like fever and vomiting, see a doctor.

Is BHT a preservative?

Food and cosmetic preservatives. Phen ol derivative butylated hydroxytoluene (BHT) is a common FDA-approved preservative used in cosmetics. Trusted Source. , and to keep food from going bad. It’s safe to consume in small amounts. But some companies have removed BHT from their foods in response to public pressure.

Is phenol bad for you?

Phenol has numerous health benefits and can be helpful to treat a few different conditions. But it can be dangerous and even deadly in high amounts. Be careful in places that may contain high levels of phenol, such as industrial facilities.

Is phenol a toxic substance?

Phenol is a type of organic compound. While toxic to consume on its own, it’s available in tiny doses in many household products like mouthwash and spray cleaners. In its pure form, it may be colorless or white. It has a mildly sugary scent that might remind you of somewhere that’s sterile, such as a hospital room.

Can you eat phenol?

This may be partly due to exposure to many other industrial chemicals in addition to phenol. Don’t eat anything that might contain phenol. Consuming phenol in its pure form can damage your esophagus, stomach, intestines, and other digestive organs.

Description

Routes of Exposure

Sources/Uses

• Phenol is obtained by fractional distillation of coal tar and by organic synthesis. By far, its largest single use is in manufacture of phenolic resins and plastics. Other uses include manufacture of explosives, fertilizers, paints, rubber, textiles, adhesives, drugs, paper, soap, wood preservatives, and photographic developers. When mixed with sla...

See more on wwwn.cdc.gov

Standards and Guidelines

Physical Properties

Health Effects

Acute Exposure

Chronic Exposure

Carcinogenicity

Reproductive and Developmental Effects