Precautions
Orphenadrine is used with rest, physical therapy, and other measures to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Orphenadrine is in a class of medications called skeletal muscle relaxants. It works by changing the way the body senses muscle pain. How should this medicine be used?
What are the side effects of orphenadrine?
Feb 28, 2022 · Orphenadrine is a muscle relaxer. Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Orphenadrine may also be used for purposes not listed in this medication guide. Warnings
Is orphenadrine an opioid?
Apr 01, 2022 · Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment …
Is orphenadrine a scheduled drug?
Orphenadrine can be used for relief of pain due to muscle spasm. The medication is not a first-choice option for short-term pain, but it's often used together with other pain-relieving methods that don't require medications, such as resting and physical therapy. COMMON BRANDS Norflex (brand no longer available) DRUG CLASS Muscle relaxant
Is orphenadrine addictive?
Orphenadrine is used to treat muscle spasms /pain. It is usually used along with rest, physical therapy, and other treatment. How to use Orphenadrine Citrate Take this …
Is orphenadrine a painkiller?
Orphenadrine can be used for relief of pain due to muscle spasm. The medication is not a first-choice option for short-term pain, but it's often used together with other pain-relieving methods that don't require medications, such as resting and physical therapy.
Is orphenadrine an anti inflammatory?
General information. Nefopam, an orphenadrine derivative, is a centrally acting non-opioid analgesic with both supraspinal and spinal sites of action. It inhibits the reuptake of serotonin, dopamine, and noradrenaline and is neither an opiate nor a non-steroidal anti-inflammatory drug.
Is Orphenadrine Citrate a painkiller?
Norgesic (orphenadrine citrate, aspirin and caffeine) is a combination of a muscle relaxant, a pain reliever, and caffeine which increases the pain relieving effects of the other drugs, used, along with rest and physical therapy, to treat injuries and other painful muscular conditions.
How does orphenadrine make you feel?
Lightheadedness warning: This drug may cause lightheadedness, dizziness, or loss of consciousness. These effects are due to a sudden drop in blood pressure. This drug can make it difficult for you to do activities that require alertness. You should not drive or use machinery until you know how this drug affects you.
Who should not take orphenadrine?
You should not take orphenadrine if you have urination problems, an enlarged prostate, glaucoma, a stomach ulcer or blockage in your digestive tract, trouble swallowing, or myasthenia gravis.Feb 28, 2022
Is orphenadrine the same as Norflex?
Orphenadrine is used treat muscle spasms and pain such as back pain and tension headaches. Find out how to take it safely and possible side effects. Orphenadrine is also called Norflex.Aug 27, 2018
Is orphenadrine a sedative?
cyclobenzaprine and orphenadrine both increase sedation. Use Caution/Monitor. cyproheptadine and orphenadrine both increase sedation.
Can orphenadrine make you sleepy?
you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how orphenadine will affect you. ask your doctor about the safe use of alcohol while you are taking this medication. Alcohol can make the side effects of orphenadrine worse.
How long does it take for orphenadrine to kick in?
Orphenadrine citrate (Norflex®) has an onset of action of one hour2 and can be used in combination with simple analgesics 5, 6. Norflex® Co, which patients can take 3-4 times daily, gets to work on the strain or spasm quickly, within 30 minutes7.Nov 1, 2018
Is orphenadrine good for anxiety?
Norflex (orphenadrine) Helps you relax. Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.
Is orphenadrine a good muscle relaxer?
Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease.
Can orphenadrine get u high?
Orphenadrine has been chronically abused for its euphoric effects. The mood elevating effects may occur at therapeutic doses of orphenadrine. No information provided. Some patients may experience transient episodes of light-headedness, dizziness or syncope.
Before Taking This Medicine
You should not use orphenadrine if you are allergic to it, or if you have: 1. urination problems; 2. an enlarged prostate; 3. glaucoma; 4. a stomac...
How Should I Take Orphenadrine?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.Orphenadrin...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Should I Avoid While Taking Orphenadrine?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.Do not drink alcohol. Dan...
Orphenadrine Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.St...
Orphenadrine Dosing Information
Usual Adult Dose for Muscle Spasm:Acute musculoskeletal conditions:100 mg orally twice a day (morning and evening).-or-60 mg by intramuscular or in...
What Other Drugs Will Affect Orphenadrine?
Taking orphenadrine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before...
Is orphenadrine a good painkiller?
Clinical guidelines don't recommend orphenadrine as a first choice option for pain relief or muscle relaxation. Other pain medications, such as ace...
Is orphenadrine an NSAID?
No, orphenadrine is not a nonsteroidal anti-inflammatory drug (NSAID), like ibuprofen (Motrin, Advil) or naproxen (Aleve, Naprosyn). Orphenadrine d...
Can you drink alcohol with orphenadrine?
Orphenadrine can cause you to be less alert and feel sleepy. Because alcohol can make you feel even less alert and sleepier, it's recommended to av...
Can you take orphenadrine if you're pregnant or breastfeeding?
It's unclear whether orphenadrine can cause harm to your unborn baby, affect your ability to produce breast milk, or be found in breast milk. To be...
What is orphenadrine used for?
Orphenadrine is a muscle relaxer. Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Orphenadrine may also be used for purposes not listed in this medication guide.
What are the side effects of orphenadrine?
dizziness, drowsiness, weakness; nausea, vomiting; dry mouth; or. constipation. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088. Orphenadrine side effects (more detail)
How to store orphenadrine?
Store orphenadrine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Keep track of the amount of medicine used from each new bottle. Orphenadrine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Can orphenadrine cause hives?
Orphenadrine side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using orphenadrine and call your doctor at once if you have: a light-headed feeling, like you might pass out; painful or difficult urination;
Can you take orphenadrine if you are allergic to it?
You should not use orphenadrine if you are allergic to it, or if you have: urination problems; an enlarged prostate; glaucoma; a stomach ulcer; a blockage in your stomach or intestines; trouble swallowing; or. myasthenia gravis.
Can you take orphenadrine if you have a stomach ulcer?
You should not take orphenadrine if you have urination problems, an enlarged prostate, glaucoma, a stomach ulcer or blockage in your digestive tract, trouble swallowing, or myasthenia gravis.
Can you crush or chew or break an extended release?
Follow your doctor's dosing instructions. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Orphenadrine is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.
What is orphenadrine used for?
Descriptions. Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease. However, this medicine does not take the place of rest, ...
Does orphenadrine help with trembling?
Orphenadrine is used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles. One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease . However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem.
How much does Orphenadrine ER cost?
ORPHENADRINE helps to relieve pain and stiffness in muscles and can treat muscle spasms. The lowest GoodRx price for the most common version of orphenadrine ER is around $22.70, 77% off the average retail price of $100.50. Prescription Settings.
What are some examples of CNS depressants?
Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; other muscle relaxants; or anesthetics, including some dental anesthetics.
Why is it important to check your progress with a doctor?
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects .
Is orphenadrine safe for elderly?
However, elderly patients are more likely to have age-related heart, liver, or kidney problems which may require caution in patients receiving orphenadrine .
Does orphenadrine help with Parkinson's?
One form of orphenadrine is also used to relieve trembling caused by Parkinson's disease. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects.
Can you drink alcohol while taking Orphenadrine?
Do not drink alcoholic beverages, and check with your doctor before taking any of the medicines listed above, while you are using this medicine. Orphenadrine may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute.
Can you take a medicine with food?
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Important warnings
Lightheadedness warning: This drug may cause lightheadedness, dizziness, or loss of consciousness. These effects are due to a sudden drop in blood pressure. This drug can make it difficult for you to do activities that require alertness. You should not drive or use machinery until you know how this drug affects you.
What is orphenadrine?
Orphenadrine is a prescription drug. It comes as an extended-release oral tablet. An extended-release tablet releases the drug into your body slowly. This drug also comes as an intravenous (IV) injection and an intramuscular (IM) injection, which are only given by a healthcare provider.
Orphenadrine side effects
Orphenadrine oral tablet may cause drowsiness, and it can also cause other side effects.
Orphenadrine may interact with other medications
Orphenadrine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
How to take orphenadrine
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
Take as directed
Orphenadrine oral tablet is used for short-term treatment. The safety of this drug for long-term treatment has not been established.
Important considerations for taking orphenadrine
Keep these considerations in mind if your doctor prescribes orphenadrine for you.
What is the phase 3 of Placebo?
Liver Cirrhosis Muscle Cramps. Drug: orphenadrine Drug: Placebo. Phase 3. Detailed Description: Muscle cramps are common in patients with liver disease and associated with significantly diminished quality of life. Patients with cirrhosis often experience muscle cramps with varied frequency and severity. The exact mechanisms by which they occur ...
Why do I get muscle cramps when I have liver disease?
The exact mechanisms by which they occur remain unclear, although a number of pathophysiological events unique to liver disease may contribute. Clinical studies have identified alterations in 3 areas: nerve function, energy metabolism, and plasma volume/electrolytes (1) Orphenadrine is an anticholinergic drug with prominent central nervous system (CNS) and peripheral actions used to treat painful muscle spasms and other similar conditions. The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including from: radiculopathy, muscles, and headaches. [3,4]
Does orphenadrine help with muscle cramps?
The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including from: radiculopathy, muscles, and headaches. [3,4] Muscle cramps are common in patients with liver disease and associated with significantly diminished quality of life.
