Healthline.com
· MUSE is a brand name for a medication (alprostadil) used for the treatment of erectile dysfunction in men. MUSE comes as a small pill or pellet that is inserted into the tip of the penis (urethra) just prior to sexual intercourse. The actual active component of this medication is alprostadil. MUSE is an effective treatment option for erectile dysfunction for some men.
Top10homeremedies.com
18 rows · · MUSE represents a unique approach for the treatment of erectile dysfunction, commonly called ...
Everydayhealth.com
· Muse. Generic name: Alprostadil Urethral Suppository [ al-PROS-ta-dill ] Drug classes: Impotence agents, Vasodilators. Medically reviewed by Drugs.com. Last updated on Oct 3, 2021. Uses; Before taking; Warnings; Dosage; Side effects; Storage; Uses of Muse: It is used to treat erectile dysfunction (ED). It may be given to you for other reasons. Talk with the doctor.
Webmd.com
Muse (alprostadil) is a medication that's injected into your penis to treat erectile dysfunction (ED). Although it works quickly, Muse (alprostadil) isn't the first choice for treating ED and it can …
Trueremedies.com
MUSE is a commonly used treatment for erectile dysfunction. The treatment consists of a urethral stick containing alprostadil which is then inserted into the urethra. It is essential that …
What is the best ED treatment?
MUSE represents a unique approach for the treatment of erectile dysfunction, commonly called impotence. It is based on the discovery that the urethra (the normal pathway for urine) can …
How do you use muse for Ed?
· MUSE works differently than sildenafil ( Viagra ), the oral therapy for ED. That is, the prostaglandin in MUSE stimulates the production of a chemical called cAMP, which, like …
Does muse suppository work for Ed?
· MUSE is the brand name of the generic medication alprostadil. Effectively, it’s a pellet that you use an applicator to insert into your urethra to produce an erection. We realize …
What is Muse Ed medication?
· Injectable alprostadil is sold under the brand names Caverject, Edex, and Prostin VR. The suppository form is called “MUSE” (which stands for Medicated Urethral System for …
How long does Muse ED last?
The erection will develop within 5-10 minutes after administration and lasts approximately 30-60 minutes. After administration of MUSE, it is important to sit, or preferably, stand or walk for about 10 minutes while the erection is developing.
Does Muse work better than Viagra?
Overall, Viagra works for about 70% of men. MUSE is effective in 30-40% of men with ED. MUSE takes effect in 5-20 minutes and the erection lasts for about an hour or until ejaculation. Viagra works as soon as 30 minutes but usually, men are advised to take it 1 hour before sex.
How well does Muse work for ED?
Muse has an average rating of 5.3 out of 10 from a total of 47 ratings for the treatment of Erectile Dysfunction. 38% of reviewers reported a positive experience, while 43% reported a negative experience.
Is Muse alprostadil still available?
Mylan discontinued Muse 125 mcg suppositories in late-May 2021.
How much does a Muse cost?
About Muse The lowest GoodRx price for the most common version of Muse is around $463.96, 18% off the average retail price of $570.09. Compare prostaglandin E1 agonists.
What are the side effects of Muse?
Common side effects of Muse include:pain in the penile pain,urethral burning,testicular pain,urethral bleeding/spotting,low blood pressure (hypotension),dizziness, or.fainting.
Does Muse hurt?
Muse (alprostadil) is a medication that's injected into your penis to treat erectile dysfunction (ED). Although it works quickly, Muse (alprostadil) isn't the first choice for treating ED and it can cause pain and burning in the penis.
Does Medicare pay for Muse?
Do Medicare prescription drug plans cover Muse? No. In general, Medicare prescription drug plans (Part D) do not cover this drug. Be sure to contact your specific plan to verify coverage information.
What is the cost of alprostadil injections?
Alprostadil costs around $143.25 for 1, 1ML of 500MCG/ML Solution of Alprostadil for uninsured customers. A SingleCare Alprostadil coupon means you will pay $19.22 for 1, 1ML of 500MCG/ML Vial of generic Alprostadil.
Is Muse available now?
There is currently no therapeutically equivalent version of Muse available in the United States.
Can you use Viagra with alprostadil?
Interactions between your drugs Sildenafil can add to the blood pressure-lowering effect of alprostadil. Contact your doctor if you experience signs and symptoms of low blood pressure such as dizziness, lightheadedness, fainting, flushing, headache, or a rapid pulse or heart rate.
What is in a Muse pill?
MUSE (alprostadil) is a prescription-only treatment for erectile dysfunction and comes in the form of individual applicators that contain a pellet of alprostadil.
How do I use Muse (alprostadil)?
Right before using Muse (alprostadil), urinate and gently shake the penis to get off any leftover urine. Open the pouch and set it aside. You'll us...
How long does it take Muse (alprostadil) to work and how long will the effects last?
Muse (alprostadil) can start to work 5-10 minutes after you administer the injection. The effects typically last about 30-60 minutes but this might...
Will it hurt to administer Muse (alprostadil)?
Pain in the penis, perineum (area between the penis and rectum), urethra, and testicles are common side effects of Muse (alprostadil). Be sure to u...
Do I have to use a condom when using Muse (alprostadil)?
If your female partner is pregnant, don't use Muse (alprostadil) unless you use a condom because Muse (alprostadil) can potentially harm a pregnant...
Can Muse (alprostadil) be used for other things?
Alprostadil is also used for newborns who are born with a heart defect where there's a hole in their heart that allows the blood to skip the circul...
What's the difference between Muse (alprostadil) and Caverject (alprostadil), Caverject Impulse (alp...
All four of these medications contain the same active ingredient called alprostadil and they're all used to treat erectile dysfunction. But Muse is...
What is the purpose of the Muse?
Muse is a prescription medicine used to treat the symptoms of Erectile Dysfunction. Muse may be used alone or with other medications. Muse belongs to a class of drugs called Prostaglandins, Genitourinary. It is not known if Muse is safe and effective in children.
How to report Muse side effects?
These are not all the possible side effects of Muse. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
How is muses delivered?
MUSE® (alprostadil) is a single-use, medicated transurethral system for the delivery of alprostadil to the male urethra. Alprostadil is suspended in polyethylene glycol 1450 (as excipient) and is formed into a medicated pellet ( micro- suppository measuring 1.4 mm in diameter by 3 mm or 6 mm in length) that resides in the tip of a translucent hollow applicator. MUSE is administered by inserting the applicator stem into the urethra after urination. The pellet containing alprostadil is delivered by depressing the applicator button (see Figure 1). The components of the delivery system are constructed of medical grade polypropylene. Each MUSE system is packaged in an individual foil pouch.
What is the pulmonary first pass metabolism of MUSE?
The near-complete pulmonary first-pass metabolism of PGE 1 is the primary factor influencing the systemic pharmacokinetics of MUSE and is a reason that peripheral venous plasma levels of P GE 1 are low or undetectable (< 2 picograms/mL) following MUSE administration. Patients with pulmonary disease therefore may have a reduced capacity to clear the drug. In patients with the adult respiratory distress syndrome ( ARDS ), pulmonary extraction of intravascularly administered alprostadil was reduced by approximately 15% compared to a control group of patients with normal respiratory function (66±3.2% vs. 78±2.4%).
What is the primary factor influencing the systemic pharmacokinetics of MUSE?
Pulmonary Disease. The near-complete pulmonary first-pass metabolism of PGE 1 is the primary factor influencing the systemic pharmacokinetics of MUSE and is a reason that peripheral venous plasma levels of PGE 1 are low or undetectable (<2 picograms/mL) following MUSE administration.
How long does Muse last?
painful or prolonged erection lasting 4 or more hours. Get medical help right away, if you have any of the symptoms listed above. The most common side effects of Muse include: pain in the penis, testicles or groin, dizziness, swelling (especially of leg veins), rapid heartbeat, and.
How long can muses be stored?
Do not expose MUSE to temperatures above 30°C (86°F). MUSE may be kept by the patient at room temperature (below 30°C or 86°F) for up to 14 days prior to use.
What are some things I need to know or do while I take Muse?
Tell all of your health care providers that you take Muse (alprostadil urethral suppository). This includes your doctors, nurses, pharmacists, and dentists.
How is this medicine (Muse) best taken?
Use Muse (alprostadil urethral suppository) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
What are some other side effects of Muse?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
If OVERDOSE is suspected
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer information use
If your symptoms or health problems do not get better or if they become worse, call your doctor.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
What is Muse (alprostadil)?
Muse (alprostadil) is a prostaglandin. It widens your blood vessels and relaxes the muscles around your penis. This allows more blood to flow to your penis to encourage an erection.
Pros and cons of Muse (alprostadil)
Available in 4 dosage strengths which may be good for people who need a larger dose to achieve an erection
Pharmacist tips for Muse (alprostadil)
Muse (alprostadil) can lower your blood pressure, which can cause dizziness, lightheadedness, blurred vision, or fainting. After using Muse (alprostadil), avoid driving or other tasks where you could get injured if you develop dizziness or fainting.
What are the side effects of Muse (alprostadil)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
What are the risks and warnings for Muse (alprostadil)?
Muse (alprostadil) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options
Interactions between Muse (alprostadil) and other medications
Muse (alprostadil) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
How much does Muse (alprostadil) cost?
There is currently no generic for Muse (alprostadil), so it can be expensive, even with insurance. GoodRx coupons, copay cards and patient assistance programs may help lower the cost.
What is muses used for?
MUSE is a commonly used treatment for erectile dysfunction. The treatment consists of a urethral stick containing alprostadil which is then inserted into the urethra.
Can you get muses on the NHS?
MUSE is available on the NHS as long as you are eligible for the erectile dysfunction treatment. These categories include factors such as being over 60 or if you have a physical disability. If you do not fall into one of these categories and you are not eligible for treatment to help with your condition on the NHS you can still visit a private doctor to be able to get MUSE on a private prescription. This will obviously cost more than an NHS prescription, but after you have been checked over by a doctor to make sure that you are able to have the treatment you will then be able to purchase the medication online at a reputable website for a discounted price.
What are the effects of MUSE?
2. Cardiovascular effects: During in-clinic dosing, patients should be monitored for symptoms of hypotension, and the lowest effective dose of MUSE should be prescribed. 3. Hematologic effects: Patients administering MUSE improperly may be at risk of urethral abrasion resulting in minor bleeding or spotting.
What is muses system?
MUSE ® (alprostadil) is a single-use, medicated transurethral system for the delivery of alprostadil to the male urethra. Alprostadil is suspended in polyethylene glycol 1450 (as excipient) and is formed into a medicated pellet (micro-suppository measuring 1.4 mm in diameter by 3 mm or 6 mm in length) that resides in the tip ...
How long does a muses erection last?
Priapism and prolonged erection: In clinical trials of MUSE, priapism (rigid erection lasting ≥ 6 hours) and prolonged erection (rigid erection lasting 4 hours and < 6 hours) were reported infrequently (< 0.1% and 0.3% of patients, respectively). Nevertheless, these events are a potential risk of pharmacologic therapy and can cause penile injury. Physicians should lower the dose or consider discontinuing MUSE treatment in any patient who develops priapism or prolonged erection.
What is the primary factor influencing the systemic pharmacokinetics of MUSE?
Pulmonary Disease. The near-complete pulmonary first-pass metabolism of PGE 1 is the primary factor influencing the systemic pharmacokinetics of MUSE and is a reason that peripheral venous plasma levels of PGE 1 are low or undetectable (< 2 picograms/mL) following MUSE administration.
How long does muses take to work?
The onset of effect is within 5-10 minutes after administration. The duration of effect is approximately 30-60 minutes. However, the actual duration will vary from patient to patient. Each patient should be instructed by a medical professional on proper technique for administering MUSE prior to self-administration.
Is muses contraindicated for urethral stricture?
1. Known hypersensitivity to alprostadil. 2. Abnormal penile anatomy: MUSE is contraindicated in patients with urethral stricture, balanitis (inflammation/infection of the glans of the penis), severe hypospadias and curvature, and in patients with acute or chronic urethritis.
How long does it take for muses to work?
There, it stimulates dilation of the arteries and provides for relaxation of the cavernosal smooth muscle within 10 to 20 minutes. The onset of a response to the MUSE is quick, usually occurring within 7 to 20 minutes after it is administered. The duration of the response varies with the dose and ranges from 60 to 80 minutes.
What is intraurethral alprostadil muses?
What is intraurethral alprostadil MUSE and how do I use it. Intraurethral alprostadil (Vivus's MUSE) is an intraurethral medication (i.e., a drug that is injected into the urethra) that was approved by the FDA in June 1998. Alprostadil is a synthetic form of a normal body chemical, prostaglandin E1, that causes increased blood flow into the penis.
Is muses an on demand medication?
MUSE is an on-demand medication, meaning that you must take it each time that you wish to achieve an erection. The suppository of the alprostadil is enclosed in a small applicator (Figure 33). You should void before inserting the tip of the applicator into your penis, because voiding helps lubricate the urethra.
Does muses work for ED?
MUSE works differently than sildenafil ( Viagra ), the oral therapy for ED. That is, the prostaglandin in MUSE stimulates the production of a chemical called cAMP, which, like cGMP, can cause the relaxation of smooth muscle and thus increase blood flow to the penis. MUSE is an on-demand medication, meaning that you must take it each time ...
How effective is muses?
Is MUSE Effective. MUSE has a success rate of about 60%, so it does work for many men that otherwise wouldn’t be able to get an erection. The success rate increases with higher doses of medicine and decreases with lower doses.
How does MUSE work?
How MUSE Works. The MUSE system consists of a medicine pellet and and applicator. The medicine is called Alprostadil, and the applicator is used to insert the pellet inside the opening of the urethra. The pellet is housed in a tube. Once the tube is inserted, you press the button to release the pellet. The medicine in MUSE is absorbed ...
What is muses urethra?
Effectively, it’s a pellet that you use an applicator to insert into your urethra to produce an erection.
How long does muses last?
The medicine in MUSE is absorbed through the membrane that lines the urethra, and an erection occurs in about 10 minutes. The erections lasts about 30 minutes and could last up to an hour. MUSE relaxes the smooth muscle walls of the blood vessels in the penis, allowing for blood to flow in.
Can you use muses while pregnant?
It also should not be ingested,so you should avoid oral sex while using it. And if your partner is pregnant, you’ll need to use a condom in conjunction with MUSE.
Does muses work for erectile dysfunction?
MUSE may work, but it also may be a little too weird for some guys to want to use.#N#For that reason, and the fact that it requires a prescription, MUSE is best suited for guys with real erectile dysfunction issues, not for guys just looking to make good things better.
How Effective Is It?
The injectable form causes an erection firm enough for sex in more than 80% of men with erectile dysfunction regardless of their age or the cause of their ED.
How Quickly Will Alprostadil Work?
It usually starts to work in about 5 to 20 minutes. Wait 10-30 minutes before you have sex. Your erection should last for about an hour and may continue after you ejaculate.
Who Should Not Take Alprostadil?
This drug is not right for everyone. Before you take it, tell your doctor:
How Do I Inject Alprostadil?
Your doctor will teach you how to give yourself the injection. If you need to prepare the mixture you’ll inject, follow the directions provided.
How Do I Insert the Suppository?
First, urinate. The small amount of urine left in the urethra will help dissolve the suppository.
How Do I Know Which One Is Right for Me?
Choosing between the injection and suppository is a personal choice. Talk to your doctor about the pros and cons. For example, the injection may be more painful, but it’s more effective than the suppository.
Precautions
If you use alprostadil (either by injection or suppository) and have sex with a pregnant woman, use a condom. Doctors don’t know if alprostadil will affect the baby.
Initiation of Therapy
Dose titration should be administered under the supervision of a physician to test a patient's responsiveness to MUSE, to demonstrate proper administration technique (see detailed instructions for MUSE administration in patient package insert), and to monitor for evidence of hypotension (see WARNINGS ).
Home Treatment Regimen
MUSE should be used as needed to achieve an erection. The maximum frequency of use is 2 administrations per 24-hour period. Each MUSE is for single use only and should be properly discarded after use.
