Treatment FAQ

what is maintenance treatment

by Prof. Roxanne Padberg Published 2 years ago Updated 2 years ago
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How long to do maintenance therapy?

Maintenance therapy is used for the following reasons: To prevent or delay the cancer’s return if the cancer is in complete remission after the initial treatment. “Complete... To slow the growth of advanced cancer after the initial treatment. This can help shrink the cancer, which is called a...

What is the role of maintenance therapy in cancer care?

To help extend the time before cancer returns, another option is maintenance treatment, which is given after a complete or partial response to platinum-based chemotherapy and may offer a chance for more time without cancer recurring. ZEJULA is approved as a maintenance treatment for women with both newly diagnosed and recurrent ovarian cancer who respond completely or …

What is skilled maintenance therapy?

Mar 29, 2021 · Maintenance therapy: Treatment designed to help the original primary treatment to succeed. Maintenance therapy may be given to patients who have cancer that is in remission to prevent a relapse.

What is Suboxone maintenance therapy?

Oct 13, 2017 · Maintenance therapy for bladder cancer typically involves a type of treatment called Bacillus Calmette-Guerin (BCG) intravesical immunotherapy. 2,3 BCG is a type of bacteria that helps the immune system to destroy cancer cells located in the bladder lining. It works by causing a reaction in a patient’s immune system that activates immune system cells and …

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What is meant by maintenance treatment?

Listen to pronunciation. (MAYN-teh-nunts THAYR-uh-pee) Treatment that is given to help keep cancer from coming back after it has disappeared following the initial therapy. It may include treatment with drugs, vaccines, or antibodies that kill cancer cells, and it may be given for a long time.

What is an example of maintenance therapy?

Examples would include therapy for a child who isn't walking or talking at the expected age. Maintenance begins when the therapeutic goals of a care plan have been achieved, or when no additional functional progress is apparent or expected to occur.Dec 21, 2017

What does maintenance chemo do?

Chemo is given on a regular schedule to keep the cancer under control. This is also called maintenance chemo. This may help curb spread and prolong survival.Jan 14, 2019

What is first line maintenance treatment?

The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment.

What is the goal of maintenance therapy?

Maintenance therapy goals include preventing unnecessary, avoidable complications from a chronic condition, such as deterioration of communication skills and reduced functional independence in activities of daily living.Nov 4, 2021

What are the signs that chemo is working?

How Can We Tell if Chemotherapy is Working?A lump or tumor involving some lymph nodes can be felt and measured externally by physical examination.Some internal cancer tumors will show up on an x-ray or CT scan and can be measured with a ruler.Blood tests, including those that measure organ function can be performed.More items...

When does maintenance stop for chemo?

Cancer treatment is at its most effective the first time that it's used. If you've undergone three or more chemotherapy treatments for your cancer and the tumors continue to grow or spread, it may be time for you to consider stopping chemotherapy.

How often do you get maintenance chemo?

Depending on the drug or combination of drugs, each treatment can last a few hours or a few days. You may have treatments every week or every 2, 3 or 4 weeks.

When does remission start?

To qualify as remission, your tumor either doesn't grow back or stays the same size for a month after you finish treatments. A complete remission means no signs of the disease show up on any tests. That doesn't mean your cancer is gone forever. You can still have cancer cells somewhere in your body.Jul 18, 2020

What is maintenance therapy psychology?

treatment or therapy designed to maintain patients in a stable condition and to promote gradual healing or prevent relapse. It usually (but not always) refers to maintenance drug therapy (maintenance pharmacotherapy or prophylactic maintenance).

What is maintenance chemo for lymphoma?

What is maintenance therapy? Maintenance therapy is a long-term treatment that usually lasts several years. It is sometimes given after an initial course of treatment has put your lymphoma into remission (your lymphoma has shrunk or gone away completely).

What is first-line vs second-line treatment?

Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren't tolerated.Jun 9, 2020

Learn more about the road ahead

You’ve been through a lot—from diagnosis to chemotherapy. But there may be more you can do than just watch and wait to see if the cancer comes back. With maintenance therapy, you can take action after your advanced ovarian cancer has responded to chemotherapy or if you’ve already experienced a recurrence.

FIRST-LINE

Being recently diagnosed with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer and having the cancer respond (completely or partially) to treatment with platinum-based chemotherapy

Why do people need maintenance therapy?

Why do some people have maintenance therapy? Healthcare providers may advise patients who have certain types of non-muscle invasive bladder cancer to have maintenance therapy to attempt to keep the bladder cancer cells from growing back after treatment , which is called recurrence. Maintenance therapy may be recommended for patients who have ...

Why is maintenance therapy important?

For maintenance therapy to be as effective as possible, it is important to maintain the regular treatment schedule, as directed by your healthcare professional, without delays or skipping treatments.

Where are bladder cancer cells located?

1 In non-muscle-invasive bladder cancer, the cancer cells are only located in the urothelium, which is the thin layer of cells that line the inside of the bladder.

Can bladder cancer recur?

Recurrence is not uncommon among patients who have been treated for non-muscle-invasive bladder cancer. Because treatment tends to be more effective when recurrence is detected early, healthcare providers will monitor patients regularly after treatment to check for signs that the cancer cells have started growing again. Maintenance therapy may also be used to potentially help reduce the risk that the bladder cancer will recur, or start growing again after the initial treatment is finished.

What is maintenance therapy?

Maintenance therapy refers to treatment given to patients after high-dose chemotherapy with autologous stem cell transplant, while continuous therapy refers to treatment given to patients who do not go on to transplant after frontline therapy.

Does Revlimid prolong life?

While maintenance or continuous therapy with Revlimid is the current standard of care for patients with standard-risk myeloma, sub-group analyses of high-risk patients in clinical trials has established that Revlimid maintenance does not prolong overall survival for many patients with high-risk cytogenetic abnormalities.

Is Velcade better than Revlimid?

It also showed that it may be more effective for other high-risk abnormalities than Revlimid.

Is there a set time period for Revlimid?

While maintenance/continuous therapy with Revlimid® is the standard of care for treatment of multiple myeloma, there is currently no set time period for the optimal duration of maintenance.

What is Velcade used for?

It has been shown to provide benefits in the treatment of multiple myeloma and mantle cell lymphoma.

What is maintenance therapy for multiple myeloma?

The goal of maintenance therapy is not to cure the cancer but to “maintain” a remission or prevent or delay the cancer's return. Clinical studies have demonstrated that Revlimid (lenalidomide), ...

How long does lenalidomide last?

After 65 months median follow-up, the median overall survival has not yet been reached for those receiving lenalidomide and is 76 months for the placebo group. Among those receiving treatment, 25 secondary primary malignancies were observed, compared to 10 in the placebo arm.

Is Tourmaline MM2 a placebo controlled trial?

TOURMALINE-MM2 is an international, randomized, double-blind, multicenter, placebo-controlled Phase 3 clinic al trial, designed to evaluate whether the addition of Ninlaro to Revlimid could improved outcomes in myeloma patients ineligible for ASCT in 705 patients. The addition of Ninlaro resulted delayed myeloma progression by 13.5 months. Ninlaro patients survived 35 months without cancer progression compared to 22 months for those treated with Revlimid and dexamethasone without Ninlaro. This improvement however did not reach "statistical significance"

Does ninlaro inhibit myeloma?

Ninlaro is referred to as a proteasome inhibitor. It produces anti-cancer effects by blocking proteins called enzymes within myeloma cells. By blocking these enzymes, the growth of the cancer cells is reduced or halted. Ninlaro appears to delay cancer progression when used following ASCT but has not been found effective following allogeneic stem cell transplant. 8,13

Does Revlimid stop myeloma?

Revlimid is an oral medication that can stop or slow the growth of cancerous myeloma cells within the bone marrow. Despite the increased risk of causing new cancers in some patients Revlimid continues to be widely used as maintenance therapy in multiple myeloma.

What is Methadone?

Methadone is a synthetic opioid agonist that is FDA-approved for use in opioid addiction treatment. It eliminates withdrawal symptoms, reduces cravings, and blocks euphoric effects of opioids such as heroin. Methadone does bind to the brain’s opioid receptors; however, it activates those receptors at a slower rate than heroin or morphine.

What are the Benefits of Methadone Maintenance?

Cravings and withdrawal symptoms make it very hard to stop using. For many individuals, such cravings hinder their success in treatment. Methadone helps individuals to focus on treatment without withdrawal symptoms or cravings as a distraction.

Is Methadone a Substitute for Illicit Opioids?

Methadone is not a substitute for abused opioids. Under medical supervision, clients do not experience the euphoric feelings associated with illicit drugs. Methadone is slower acting, with a therapeutic dose typically lasting 24-36 hours. Heroin has a much shorter half-life, about three to six hours.

What to Expect in Methadone Maintenance

Those in a methadone maintenance treatment program typically take methadone daily in a supervised clinical setting. FDA-approved methadone products are administered in liquid or tablet form. The appropriate dose is unique to each individual. Dosage may change based on clients’ progress in treatment.

How Long Does Treatment Last?

This is entirely dependent on the client; however, when taken under medical supervision, treatment can last indefinitely as long as it remains beneficial for the client. Some individuals may reduce their dose but remain on methadone, while others eventually become abstinent.

When is Methadone Maintenance Recommended?

Methadone maintenance may be recommended for individuals with a history of opioid dependence or who have not had success with treatment previously.

Methadone Maintenance at Pyramid

Methadone maintenance is offered through Pyramid Healthcare’s Medication-Assisted Treatment (MAT) program. We have methadone maintenance treatment programs throughout Pennsylvania. MAT is available at Pyramid treatment centers in Pennsylvania, New Jersey, and Virginia.

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