
Medication
Treatments for infertility can range from medications to embryo implantation through assisted reproductive technology (ART). There are treatments that are specifically for men or for women and some that involve both partners.
Procedures
Unexplained infertility: The logic behind using ICSI to treat unexplained infertility is that since we don’t know what is wrong, treating every possibility is a good plan of action. That said, so far research has not found that ICSI for unexplained infertility significantly improves live birth success rates.
Self-care
Severe male infertility isn’t the only reason ICSI-IVF is used. Other evidence-based reasons for ICSI include: Previous IVF cycle had few or no fertilized eggs: Sometimes, a good number of eggs are retrieved, and sperm counts look healthy, but no eggs get fertilized.
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However, IUI may be selected as a fertility treatment for any of the following conditions as well: 1 Unexplained infertility 2 A hostile cervical condition, including cervical mucus problems 3 Cervical scar tissue from past procedures which may hinder the sperms’ ability to enter the uterus 4 Ejaculation dysfunction
What are the treatment options for infertility?
Does ICSI work for unexplained infertility?
Why is ICSI-IVF used for severe male infertility?
What conditions can IUI be used to treat?

How is IVF different from ICSI?
IVF and ICSI are forms of assisted reproductive treatment (ART) in which eggs are fertilised with sperm outside the body. IVF is used for female infertility and unexplained infertility, and ICSI is used when there is a male cause of infertility.
Is ICSI more successful than IVF?
And they're in good company. New Scientist reports that a recent study revealed that ICSI boasts a pregnancy success rate of 24%. While IVF without ICSI still has a slightly higher pregnancy success rate at 27%, those aren't bad odds for anyone who's already tried other methods of assisted reproductive technology.
Can ICSI be done without IVF?
IVF simply means in vitro fertilization and it can be completed with or without ICSI treatment. If your fertility diagnosis includes insufficient sperm parameters (male factor infertility) you probably will undergo ICSI in addition to IVF.
Does ICSI cost more than IVF?
Cost. The ICSI procedure costs between $1,400 to $2,000. This is on top of the general IVF cost, which on average costs $12,000 to $15,000. It may cost more than this if other IVF options are being used.
How much does ICSI treatment cost?
On average, ICSI costs range from $800 - $2,500, depending on where you have it performed. Nearly all ICSI is done in-house at your clinic's laboratory, where we estimate the clinic's costs to perform ICSI are in the $50 - $250 range.
Is ICSI babies are normal?
Findings from some but not all studies suggest that ICSI is associated with an increased risk for chromosomal abnormalities, autism, intellectual disabilities, and birth defects compared with conventional IVF. These increased risks may also be due to the effects of subfertility.
How do they pick sperm for ICSI?
Initially, a sperm sample is prepared using multiple techniques in order to eliminate poor quality sperm. The remaining specimen of “healthy” sperm is then placed under high-magnification for visual inspection by an embryologist. The embryologist will select the “best looking” sperm using a fine glass needle.
Does ICSI work first time?
Couples who have more severe problems such as low sperm counts or movement will have an even higher rate of fertilization failure. Therefore, at IVF1, our recommendation to increase the chance for 1st time IVF success is to use ICSI for fertilization EVEN IF there are no known sperm problems.
Is ICSI treatment painful?
No, ICSI is not a painful procedure. During the process of IVF/ICSI, the patient is anxious about the procedure being painful. However, there is no part of the procedure in which the patient may experience pain.
Does ICSI affect gender?
Since it is the sperm that determines the embryo's sex, ICSI doesn't affect the baby's gender in any way.
Can you have twins with ICSI?
Abstract. Twin pregnancies constitute the most serious complication for both mother and children after IVF/ICSI treatment, but transfer of at least two `best looking' embryos remains the standard policy.
How many eggs are needed for ICSI?
One requirement for split ICSI is a minimum number of mature eggs. We must be able to identify at least eight mature eggs on the day of your egg retrieval in order to proceed with split ICSI. If this requirement is not met, we will inject all of your mature eggs.
What is ICSI IVF?
Pronounced ick-see IVF, ICSI stands for intracytoplasmic sperm injection. During regular IVF, many sperm are placed together with an egg, in hopes that one of the sperm will enter and fertilize the egg on its own. With ICSI-IVF, the embryologist takes a single sperm and injects it directly into an egg. 1 .
Why should ICSI not be used for every IVF cycle?
There is also a slightly increased risk of a male baby having fertility problems in the future. This is because male infertility may be passed on genetically. These additional risks are why many doctors are saying ICSI should not be used for every IVF cycle. 1 It's one thing if you need ICSI to conceive.
Why do we use ICSI?
Sperm retrieved through TESE require the use of ICSI. ICSI is also used in cases of retrograde ejaculation if the sperm are retrieved from the man's urine. Severe male infertility isn’t the only reason ICSI-IVF is used. Other evidence-based reasons for ICSI include: 2 .
How many eggs are fertilized with ICSI?
The ICSI procedure fertilizes 50 to 80 percent of eggs. You might assume all eggs get fertilized with ICSI-IVF, but they don’t. Fertilization isn’t guaranteed even when a sperm is injected into the egg. Remember that fertilization rates don’t tell you the clinical pregnancy or live birth rates.
How much does ICSI cost?
The ICSI procedure costs between $1,400 to $2,000. This is on top of the general IVF cost, which on average costs $12,000 to $15,000. It may cost more than this if other IVF options are being used.
What is a low sperm count?
Very low sperm count (also known as oligospermia) Abnormally shaped sperm (also known as teratozoospermia) Poor sperm movement (also known as asthenozoospermia) If a man does not have any sperm in his ejaculate, but he is producing sperm, they may be retrieved through testicular sperm extraction or TESE.
How long does it take for an embryo to be transferred after IVF?
If fertilization takes place, and the embryos are healthy, an embryo or two will be transferred to your uterus, via a catheter placed through the cervix, two to five days after the retrieval. You can get more detailed information here in this IVF Treatment Step by Step .
How does IVF work?
IVF allows us to maximise the chance of fertilisation by placing eggs with sperm. We can choose the embryo with the highest potential for pregnancy thanks to our advanced embryo selection techniques, which include time-lapse monitoring and Preimplantation Genetic Screening. If you have more than one good embryo from your cycle, you can freeze the remainder to use in future treatment cycles.
What is ICSI treatment?
ICSI is a treatment designed to overcome male fertility issues, such as low sperm count or poor sperm mobility, which prevents sperm from fertilising the egg naturally. It’s also used for surgically-retrieved sperm, or for men whose sperm has high levels of DNA damage. If sperm issues aren’t the cause of your fertility problems, ...
Why do IVF women need to be advised?
Why IVF may be advised. IVF is designed to overcome issues that prevent sperm from fertilising an egg in the body, such as fallopian tube damage or blockages . It may also be advised in some cases of unexplained infertility, or in mild cases of male infertility.
What is IVF in a lab?
IVF – In-Vitro Fertilisation - involves the use of fertility drugs to gently stimulate your ovaries to produce quality mature eggs, which are retrieved and then fertilised in our laboratory with sperm from either your partner or a donor. Sperm and eggs are placed together in a special dish and eggs monitored for signs of fertilisation.
What is IUI in pregnancy?
IUI is short for Intrauterine Insemination. It involves inserting your partner’s sperm – or donor sperm – into your uterus at the time you are ovulating, in the hope the egg is fertilised for pregnancy.
Why do I need ICSI?
ICSI helps you get pregnant when your partner has sperm problems. Because the sperm is injected it bypasses the other stages of early fertilisation. . Only the best quality sperm is used for fertilisation, as identified by one of our Embryologists.
How are eggs and sperm placed together?
Sperm and eggs are placed together in a special dish and eggs monitored for signs of fertilisation. The best quality resulting embryo is selected for transfer, where it’s placed into your uterus to implant and grow for pregnancy.
What are some examples of medications used to treat infertility?
The most common medications used to treat infertility help stimulate ovulation. Examples of these types of medications include: 2, 3. Clomiphene is a medication patients take by mouth (orally).
How likely is a woman to get treatment for infertility?
Fertility Treatments for Females. Once a woman is diagnosed with infertility , the overall likelihood for successful treatment is 50%. 1. Whether a treatment is successful depends on: Fertility treatments are most likely to benefit women whose infertility is due to problems with ovulation. Treatment with medications is least likely ...
What is the best medicine for high prolactin levels?
Bromocriptine or Cabergoline. Bromocriptine and cabergoline are pills taken orally to treat abnormally high levels of the hormone prolactin, which can interfere with ovulation. 2 Pituitary growths; certain medications, including antidepressants; kidney disease; and thyroid disease can cause high levels of prolactin.
What is ectopic pregnancy?
These surgeries involving the fallopian tubes also increase the risk of ectopic (pronounced ek-TAH-pik) pregnancy, which is a pregnancy that occurs outside of the uterus. 1 Ectopic pregnancies are also called "tubal pregnancies," because they most often occur in a fallopian tube. 6.
Can in vitro fertilization help with infertility?
Treatment with medications is least likely to benefit infertility caused by damage to the fallopian tubes or severe endometriosis, although in vitro fertilization can help women with these conditions to conceive. 1. The first step of treating infertility in many cases is to treat the underlying cause of infertility.
Does clomiphene cause ovulation?
Patients take clomiphene in the beginning of the menstrual cycle. Clomiphene causes ovulation to occur in 80% of women treated. About half of those who ovulate are able to achieve a pregnancy or live birth. 2. Use of clomiphene increases the risk of having a multiple pregnancy.
What are the treatments for a woman's fertility?
Treatments can include lifestyle changes, vitamins and supplements, surgery, medication, or assisted reproduction.
How old do you have to be to conceive?
The American Society for Reproductive Medicine recommends consulting a health care provider if a woman is under 35 years old and has been trying to conceive for more than 12 months, or is over 35 years old and has been trying to conceive for over 6 months. Fertility treatments can increase the likelihood ...
What is ICSI in a woman's egg?
What is Intracytoplasmic Sperm Injection (ICSI)? Before a man’s sperm can fertilize a woman’s egg, the head of the sperm must attach to the outside of the egg. Once attached, the sperm pushes through the outer layer to the inside of the egg (cytoplasm), where fertilization takes place.
How many eggs are fertilized in ICSI?
ICSI fertilizes 50% to 80% of eggs. But the following problems may occur during or after the ICSI process: Some or all of the eggs may be damaged. The egg might not grow into an embryo even after it is injected with sperm. The embryo may stop growing.
Why can't sperm penetrate the outer layer of an egg?
In these cases, a procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) to help fertilize the egg.
How long does it take for an embryo to grow?
With either traditional IVF or ICSI, once fertilization occurs, the fertilized egg (now called an embryo) grows in a laboratory for 1 to 5 days before it is transferred to the woman’s uterus (womb).
What are the conditions associated with ICSI?
Certain conditions have been associated with the use of ICSI, such as Beckwith-Wiedemann syndrome, Angelman syndrome, hypospadias, or sex chromosome abnormalities. They are thought to occur in far less than 1% of children conceived using this technique. Some of the problems that cause infertility may be genetic.
Can sperm move in a normal fashion?
The sperm may not move in a normal fashion. The sperm may have trouble attaching to the egg. A blockage in the male reproductive tract may keep sperm from getting out. Eggs have not fertilized by traditional IVF, regardless of the condition of the sperm. In vitro matured eggs are being used.
What doctor can help with infertility?
Depending on your age and personal health history, your doctor may recommend a medical evaluation. A gynecologist, urologist or family doctor can help determine whether there's a problem that requires a specialist or clinic that treats infertility problems.
What to do before infertility testing?
Before infertility testing, your doctor or clinic works to understand your sexual habits and may make recommendations to improve your chances of getting pregnant. In some infertile couples, no specific cause is found (unexplained infertility). Infertility evaluation can be expensive, and sometimes involves uncomfortable procedures.
What is the reproductive tract?
The reproductive tract must allow an egg to pass into the fallopian tubes and join with sperm for fertilization. The fertilized egg must travel to the uterus and implant in the lining. Tests for female infertility try to find out if any of these processes are impaired.
What is the substance that is injected into the uterus called?
In HSG, a thin tube is threaded through the vagina and cervix. A substance known as contrast material is injected into the uterus. A series of X-rays, or fluoroscopy, follows the dye, which appears white on X-ray, as it moves into the uterus and then into the tubes.
How to increase sperm count?
Certain medications may improve sperm count and likelihood for achieving a successful pregnancy. These medicines may increase testicular function, including sperm production and quality. Surgery. For some conditions, surgery may be able to reverse a sperm blockage and restore fertility.
Where is the fertilized egg transferred?
The fertilized egg (embryo) is transferred into the uterus (C). In intracytoplasmic sperm injection (ICSI), a single healthy sperm is injected directly into each mature egg. ICSI is often used when semen quality or number is a problem or if fertilization attempts during prior in vitro fertilization cycles failed.
What to include in a medical list for infertility?
Make a list of any medications, vitamins, herbs or other supplements you take. Include the doses and how often you take them. Make a list of questions to ask your doctor.
When is IUI used?
The most common reasons for IUI are low sperm count or decreased sperm mobility. However, IUI may be selected as a fertility treatment for any of the following conditions as well:
How does IUI work?
Before intrauterine insemination, ovulation- stimulating medications may be used, in which case careful monitoring will be necessary to determine when the eggs are mature.
What are the risks?
The chance of becoming pregnant with multiples is increased if you take fertility medication when having IUI. There is also a small risk of infection after IUI.

Overview
Why Is ICSI-IVF done?
Controversial Uses
ICSI-IVF
Specialist to consult
Cost
Risks
- ICSI-IVF is typically used in cases of severe male infertility, including:2 1. Very low sperm count (also known as oligospermia) 2. Abnormally shaped sperm (also known as teratozoospermia) 3. Poor sperm movement (also known as asthenozoospermia) If a man does not have any sperm in his ejaculate, but he is producing sperm, they may be retrieved through testicular sperm extracti…
Success Rate
- IVF with ICSI can be a great technology when needed. However, there’s some disagreement on when it can and can’t improve success rates. Research is ongoing, but here are some situations that the American Society of Reproductive Medicine reports IVF with ICSI may not be warranted: 1. Very few eggs retrieved: The concern is that with so few eggs, why take a risk that they won’t …