Treatment FAQ

what is in remdesivir treatment

by Prof. Roosevelt Mraz Published 3 years ago Updated 2 years ago
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Remdesivir is a nucleotide prodrug of an adenosine analog. It binds to the viral RNA-dependent RNA polymerase and inhibits viral replication by terminating RNA transcription prematurely. Remdesivir has demonstrated in vitro activity against SARS-CoV-2.

What is remdesivir used for?

Aug 05, 2021 · Abstract Background: Remdesivir is an antiviral medicine with properties to inhibit viral replication of SARS-CoV-2. Positive results from early studies attracted media attention and led to emergency use authorisation of remdesivir in COVID-19.

Where should remdesivir be administered?

Feb 07, 2022 · Remdesivir. Generic name: remdesivir (rem DES i veer) Brand names: Veklury. Dosage forms: intravenous powder for injection (100 mg); intravenous solution (5 mg/mL) Drug class: Investigational drugs, Purine nucleosides. Medically reviewed by Drugs.com on Feb 7, 2022. Written by Cerner Multum. Uses. Warnings.

What is the generic name for remdesivir?

Remdesivir is a broad-spectrum antiviral drug. Used for treatment of COVID-19 infection caused by the SARS-CoV-2 virus. 24/7 Appointment Helpline +91 40 4567 4567 International +91 40 6600 0066 Home About Us Leadership Team Awards & Recognition Achievements Gallery News Events Medical Updates News Gallery Locations Secunderabad Somajiguda Malakpet

Can remdesivir be used to treat hepatitis?

• Remdesivir is an antiviral medicine which directly kills COVID-19 in the body. It may stop the virus from multiplying in your body. Who can it help ? • Remdesivir can be used to treat adults 18 years and older who are at higher risk of severe illness and needing to go to the hospital for COVID-19. This includes people who are:

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What is Remdesivir?

Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body.

What are the side effects of Remdesivir?

Remdesivir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:• nausea• constipation• pain, bleeding, bruising of the skin, soreness, or swelling near the place where the medication was injected

How does Remdesivir work against covid-19?

Remdesivir works by blocking the virus from copying itself. Trials of the drug showed that it can cut recovery time from COVID-19 by nearly a third in people with severe COVID-19.Aug 24, 2020

Is Remdesivir approved to treat COVID-19?

Remdesivir is a nucleotide analogue prodrug that is approved to treat COVID-19 in certain patients.

Are long term side effects possible with the COVID-19 vaccine?

Benefits of Vaccination Outweigh the Risks Serious side effects that could cause a long-term health problem are extremely unusual following any vaccination, including COVID-19 vaccination.

Is it possible to have lingering symptoms of COVID-19?

"Some symptoms of COVID-19 linger longer than others," says Dr. Septimus. "In particular, fatigue and loss of taste and smell can persist beyond the period of contagion."While uncomfortable and/or inconvenient, Dr. Septimus adds that these lingering symptoms aren't too worrisome for most people.Jan 5, 2022

How do live attenuated Covid vaccines work?

Whole virus Live attenuated vaccines use a weakened form of the virus that can still replicate without causing illness. Inactivated vaccines use viruses whose genetic material has been destroyed so they cannot replicate, but can still trigger an immune response.Dec 18, 2020

How well does Paxlovid work?

How well does Paxlovid work? When it applied for FDA authorization, Pfizer presented data from a clinical trial conducted in 2021. The data showed that participants who were given Paxlovid were 89% less likely to develop severe illness and death compared to trial participants who received a placebo.Mar 10, 2022

How long do COVID-19 antibodies last?

At this time, it is unknown for how long antibodies persist following infection and if the presence of antibodies confers protective immunity.Jan 31, 2022

Is Remdesivir approved in Europe for treatment of COVID-19?

Since July 2020, remdesivir has been conditionally approved in Europe for the treatment of coronavirus disease (COVID-19) in adults and adolescents aged 12 years and older with pneumonia who require supplemental oxygen but no invasive ventilation.Jul 6, 2021

What is the first drug that was approved by the FDA to treat COVID-19?

Remdesivir is the first drug approved by the FDA for treatment of hospitalized COVID patients over the age of 12.Jan 25, 2022

Which drug is approved by FDA to treat COVID-19?

Veklury (Remdesivir) is an antiviral drug approved for use in adults and pediatric patients [12 years of age and older and weighing at least 40 kilograms (about 88 pounds)] for the treatment of COVID-19 requiring hospitalization.Mar 31, 2022

What is Remdesivir?

Remdesivir is a broad-spectrum antiviral drug that has become popular because of its ability to treat coronavirus disease. Developed to treat Ebola...

What are the uses of Remdesivir?

Remdesivir is used to treat COVID-19 infection caused by the SARS-CoV-2 virus. It stops the COVID virus from spreading in the body and causing seve...

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What are the side effects of Remdesivir?

Remdesivir side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Some side effects may occur during or after the injection. Tell your caregiver right away if you have:

How long does it take to get Remdesivir?

remdesivir must be given slowly, and the infusion can take 30 to 120 minutes to complete. Remdesivir is usually given once per day for 5 to 10 days. You will need frequent blood tests to check your liver function.

How much does Remdesivir weigh?

Remdesivir is for use in adults and children at least 12 years old and weighing at least 88 pounds (40 kilograms). Remdesivir may also be used for purposes not listed in this medication guide.

What are the side effects of a syringe?

Some side effects may occur during or after the injection. Tell your caregiver right away if you have: 1 severe headache, pounding in your neck or ears; 2 fast, slow, or pounding heartbeats; 3 wheezing, trouble breathing; 4 swelling in your face; 5 nausea; 6 fever, chills, or shivering; 7 itching, sweating; or 8 a light-headed feeling, like you might pass out;

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Monitoring and Adverse Effects

In the US, remdesivir is approved by the FDA to treat coronavirus infection, also known as COVID-19, for certain patients who are in the hospital. In Canada, remdesivir has not been approved by Health Canada for general use. However, Health Canada is allowing remdesivir to be used in human studies and for conditional use in hospitalized patients. More information about remdesivir is available from the US manufacturer's Patient Information leaflet, or should be provided by the doctor from the Informed Consent form for a study or the Health Canada Patient Medication Information for conditional use.

May Treat: COVID-19

Brand Names: Veklury

Drug Class: SARS-CoV-2 Antiviral Agents - RNA Polymerase Inhibitor

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Consult a doctor before using

Drug-Drug Interactions

Considerations in Pregnancy

Considerations in Children

  • Remdesivir can cause gastrointestinal symptoms (e.g., nausea), elevated transaminase levels, an increase in prothrombin time without a change in the international normalized ratio, and hypersensitivity reactions. Liver function tests and prothrombin time tests should be performe…
See more on covid19treatmentguidelines.nih.gov

Clinical Trials

  • Currently, no clinical drug-drug interaction studies of remdesivir have been conducted. In vitro, remdesivir is a minor substrate of cytochrome P450 (CYP) 3A4 and a substrate of the drug transporters organic anion transporting polypeptide (OATP) 1B1 and P-glycoprotein. It is also an inhibitor of CYP3A4, OATP1B1, OATP1B3, and multidrug and toxin extrusion protein 1 (MATE1).…
See more on covid19treatmentguidelines.nih.gov

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