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what is diabetes mellitus type 2 & treatment

by Charlie Cassin Published 2 years ago Updated 2 years ago
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What are some causes of diabetes type 2?

Dec 11, 2018 · Type 2 diabetes is a chronic disease. It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes. That's because it used to start almost always in middle- and late-adulthood. However, more and more children and teens are developing this condition.

What is the best treatment for type 2 diabetes?

Dec 09, 2021 · What is type 2 diabetes? Type 2 diabetes, the most common type of diabetes, is a disease that occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is your main source of energy and comes mainly from the food you eat. Insulin, a hormone made by the pancreas, helps glucose get into your cells to be used for energy. In type 2 diabetes, your …

What is the difference between Type 1 and Type 2 diabetes?

Jan 25, 2022 · Type 2 diabetes is a chronic disease. It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes. That's because it used to start almost always in middle- and late-adulthood. However, more and more children and teens are developing this condition.

What is the difference between Type 1 and Type 2?

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Aug 30, 2020 · Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Because insulin release and activity are essential processes for glucose homeostasis, the molecular …

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Type 2 Diabetes With type 2 diabetes, your body doesn’t use insulin well and can’t keep blood sugar at normal levels. About 90-95% of people with diabetes have type 2. It develops over many years and is usually diagnosed in adults (but more and more in children, teens, and young adults).

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What is meant by type 2 diabetes mellitus?

Overview. Type 2 diabetes is an impairment in the way the body regulates and uses sugar (glucose) as a fuel. This long-term (chronic) condition results in too much sugar circulating in the bloodstream. Eventually, high blood sugar levels can lead to disorders of the circulatory, nervous and immune systems.Jan 20, 2021

What is the difference between type 2 diabetes and diabetes mellitus?

Type 2 diabetes is a chronic disease. It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes. That's because it used to start almost always in middle- and late-adulthood.

What causes diabetes mellitus 2?

What causes Type 2 diabetes? Type 2 diabetes develops when the pancreas makes less insulin than the body needs, and the body cells stop responding to insulin. They don't take in sugar as they should. Sugar builds up in your blood.Mar 25, 2021

Is diabetes mellitus type 2 fatal?

Type 2 diabetes is a serious condition that can lead to life-threatening complications. However, by adopting effective management strategies, there is a good chance that many people with type 2 diabetes can expect to live as long as a person without the condition.Mar 27, 2019

What are the 3 signs of diabetes mellitus?

The main symptoms of diabetes are described as the three polys - polyuria, polydipsia, and polyphagia. Individuals with high risk for developing diabetes should be alert to these symptoms and seek medical attention if they notice the above symptoms.

What's the worst type of diabetes?

Type 2 diabetes causes The primary problem in type 2 diabetes is the inability of the body's cells to use insulin properly and efficiently, leading to hyperglycemia (high blood sugar) and diabetes. This problem affects mostly the cells of muscle and fat tissues and results in a condition known as insulin resistance.

Which is worse type 1 or 2 diabetes?

Type 2 diabetes is often milder than type 1. But it can still cause major health complications, especially in the tiny blood vessels in your kidneys, nerves, and eyes. Type 2 also raises your risk of heart disease and stroke.Dec 8, 2021

What are 10 warning signs of diabetes?

Early signs and symptoms of diabetesFrequent urination. When your blood sugar is high, your kidneys expel the excess blood sugar, causing you to urinate more frequently. ... Increased thirst. ... Fatigue. ... Blurred vision. ... Increased hunger. ... Unexplained weight loss. ... Slow healing cuts and wounds. ... Tingling or numbness in the hands or feet.More items...•Jun 24, 2021

Can you get rid of type 2 diabetes?

According to recent research, type 2 diabetes cannot be cured, but individuals can have glucose levels that return to non-diabetes range, (complete remission) or pre-diabetes glucose level (partial remission) The primary means by which people with type 2 diabetes achieve remission is by losing significant amounts of ...

How long can a woman live with type 2 diabetes?

Average life expectancy in 2015 in the non-diabetic population is around 74.8 years with longer life expectancy for the female than male population (78 years vs 71) (Table 2). Patients with Type 1 DM and with Type 2 DM are expected to have an average life of 70.96 and 75.19 years at the end of observed period.May 11, 2020

Does type 2 diabetes get worse with age?

Your risk of developing type 2 diabetes increases with age. This may be because people tend to gain weight and exercise less as they get older. Maintaining a healthy weight by eating a healthy, balanced diet and exercising regularly are ways of preventing and managing diabetes.May 27, 2021

What is the life expectancy of someone with diabetes type 2?

For type 2 diabetes, the average patient was 65.4 years old and had a life expectancy from now of 18.6 years. In comparison, patients the same age without diabetes were expected to live 20.3 years from now.Sep 23, 2020

What is type 2 diabetes?

What Is It? Type 2 diabetes is a chronic disease. It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes.

Is type 2 diabetes more common than type 1 diabetes?

Type 2 diabetes is much more common than type 1 diabetes, and is really a different disease. But it shares with type 1 diabetes high blood sugar levels, and the complications of high blood sugar. During digestion, food is broken down into basic components.

Why is Type 2 diabetes so bad?

Type 2 diabetes is primarily the result of two interrelated problems: Cells in muscle, fat and the liver become resistant to insulin. Because these cells don't interact in a normal way with insulin, they don't take in enough sugar. The pancreas is unable to produce enough insulin to manage blood sugar levels.

Which race is more likely to develop type 2 diabetes?

Although it's unclear why, people of certain races and ethnicities — including Black, Hispanic, Native American and Asian people, and Pacific Islanders — are more likely to develop type 2 diabetes than white people are. Blood lipid levels.

Why is physical activity important for diabetes?

The less active you are, the greater your risk. Physical activity helps control your weight, uses up glucose as energy and makes your cells more sensitive to insulin. Family history. The risk of type 2 diabetes increases if your parent or sibling has type 2 diabetes. Race and ethnicity.

How long can you live with type 2 diabetes?

Signs and symptoms of type 2 diabetes often develop slowly. In fact, you can be living with type 2 diabetes for years and not know it. When signs and symptoms are present, they may include:

What happens if you have high blood sugar?

Eventually, high blood sugar levels can lead to disorders of the circulatory, nervous and immune systems. In type 2 diabetes, there are primarily two interrelated problems at work. Your pancreas does not produce enough insulin — a hormone ...

What happens when your glucose levels are low?

When your glucose levels are low, such as when you haven't eaten in a while, the liver breaks down stored glycogen into glucose to keep your glucose level within a normal range. In type 2 diabetes, this process doesn't work well.

Where does insulin come from?

Insulin is a hormone that comes from the gland situated behind and below the stomach (pancreas). Insulin regulates how the body uses sugar in the following ways: Sugar in the bloodstream triggers the pancreas to secrete insulin. Insulin circulates in the bloodstream, enabling sugar to enter your cells.

How to reduce risk of diabetes type 2?

Here are some things you can do to lower your risk: Lose weight if you are overweight, and keep it off.

How old do you have to be to get Type 2 diabetes?

You are more likely to develop type 2 diabetes if you are age 45 or older, have a family history of diabetes, or are overweight or obese. Diabetes is more common in people who are African American, Hispanic/Latino, American Indian, Asian American, or Pacific Islander. Physical inactivity and certain health problems such as high blood pressure ...

How to manage diabetes?

Lifestyle changes that include planning healthy meals, limiting calories if you are overweight, and being physically active are also part of managing your diabetes. So is taking any prescribed medicines. Work with your health care team to create a diabetes care plan that works for you.

How to reduce calories in diabetics?

Choosing foods with less fat is another way to reduce calories. Drink water instead of sweetened beverages. Ask your health care team what other changes you can make to prevent or delay type 2 diabetes. Most often, your best chance for preventing type 2 diabetes is to make lifestyle changes that work for you long term.

What are the problems that can be caused by diabetes?

However, if not managed, diabetes can lead to problems such as. heart disease and stroke. nerve damage. kidney disease. foot problems. eye disease. gum disease and other dental problems. sexual and bladder problems. Many people with type 2 diabetes also have nonalcoholic fatty liver disease (NAFLD).

What are the symptoms of diabetes?

feeling tired. blurred vision. numbness or tingling in the feet or hands. sores that do not heal. unexplained weight loss. Symptoms of type 2 diabetes often develop slowly—over the course of several years—and can be so mild that you might not even notice them. Many people have no symptoms.

What is the most common type of diabetes?

Type 2 diabetes, the most common type of diabetes, is a disease that occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is your main source of energy and comes mainly from the food you eat. Insulin, a hormone made by the pancreas, helps glucose get into your cells to be used for energy.

What is type 2 diabetes?

It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes. That's because it used to start almost always in middle- and late-adulthood. However, more and more children and teens are developing this condition.

Why do people with type 2 diabetes take insulin?

Because type 2 diabetes develops when the pancreas cannot make enough insulin to overcome insulin resistance, about one of three people with this disease take some form of insulin injection.

What is it called when the pancreas produces more insulin?

This condition is called insulin resistance .

How to diagnose diabetes?

Diagnosis. Diabetes is diagnosed by testing the blood for sugar levels. Blood is tested in the morning after you have fasted overnight. Typically, the body keeps blood sugar levels between 70 and 100 milligrams per deciliter (mg/dL), even after fasting.

What is the name of the condition where you have a high blood sugar level?

Extremely high blood sugar levels also can lead to a dangerous complication called hyperosmolar syndrome. This is a life-threatening form of dehydration. In some cases, hyperosmolar syndrome is the first sign that a person has type 2 diabetes. It causes confused thinking, weakness, nausea and even seizure and coma.

How to restore blood sugar levels in type 2 diabetes?

However, people with type 2 diabetes can sometimes restore their blood sugar levels to normal just by eating a healthy diet, regularly exercising, and losing weight.

Is glucose a type 1 diabetes?

But it shares with type 1 diabetes high blood sugar levels, and the complications of high blood sugar. During digestion, food is broken down into basic components. Carbohydrates are broken down into simple sugars, primarily glucose. Glucose is a critically important source of energy for the body's cells.

Why is diabetes a secondary disease?

Secondary diabetes is caused due to the complication of other diseases affecting the pancreas (for example, pancreatitis), hormone disturbances (for example, Cushing disease), or drugs (for example, corticosteroids). Epidemiology. Diabetes is a worldwide epidemic.

What is T2DM in a diabetic?

In T2DM, the response to insulin is diminished, and this is defined as insulin resistance. During this state, insulin is ineffective and is initially countered by an increase in insulin production to maintain glucose homeostasis, but over time, insulin production decreases, resulting in T2DM.

What are the complications of diabetes mellitus?

Complications. Persistent hyperglycemia in uncontrolled diabetes mellitus can cause several complications, both acute and chronic. Diabetes mellitus is one of the leading causes of cardiovascular disease (CVD), blindness, kidney failure, and amputation of lower limbs.

What are some examples of monogenic diabetes?

Examples of monogenic diabetes include conditions like neonatal diabetes mellitus and maturity-onset diabetes of the young (MODY). Around 1 to 5% of all diabetes cases are due to monogenic diabetes. MODY is a familial disorder and usually presents under the age of 25 years. Secondary Diabetes.

What is the T1DM?

In T1DM, there is cellular-mediated, autoimmune destruction of pancreatic beta cells. T1DM has a strong genetic predisposition. The major histocompatibility complex (MHC), also known as human leukocyte antigens (HLA), is reported to account for approximately 40 to 50% of the familial aggregation of T1DM.

What happens to beta cells in T2DM?

As the disease progresses, beta cells change, and insulin secretion is unable to maintain glucose homeostasis, producing hyperglycemia. Most of the patients with T2DM are obese or have a higher body fat percentage, distributed predominantly in the abdominal region.

Why is T2DM a fetal condition?

T2DM is caused due to duel defects in insulin resistance and insulin secretion. Gestational diabetes is associated with maternal as well as fetal complications. Exercise and a healthy diet are beneficial in both type 1 and type 2 diabetes mellitus.

How does diabetes type 2 affect blood sugar?

With type 2 diabetes, your body doesn’t use insulin well and can’t keep blood sugar at normal levels. About 90-95% of people with diabetes have type 2. It develops over many years and is usually diagnosed in adults (but more and more in children, teens, and young adults). You may not notice any symptoms, so it’s important to get your blood sugar tested if you’re at risk. Type 2 diabetes can be prevented or delayed with healthy lifestyle changes, such as losing weight, eating healthy food, and being active.

How many people have type 1 diabetes?

Approximately 5-10% of the people who have diabetes have type 1. Symptoms of type 1 diabetes often develop quickly. It’s usually diagnosed in children, teens, and young adults. If you have type 1 diabetes, you’ll need to take insulin every day to survive.

What happens when your blood sugar goes up?

When your blood sugar goes up, it signals your pancreas to release insulin.

Why does my body not make enough insulin?

If you have diabetes, your body either doesn’t make enough insulin or can’t use the insulin it makes as well as it should. When there isn’t enough insulin or cells stop responding to insulin, too much blood sugar stays in your bloodstream.

Can gestational diabetes cause health problems?

Gestational diabetes develops in pregnant women who have never had diabetes. If you have gestational diabetes, your baby could be at higher risk for health problems. Gestational diabetes usually goes away after your baby is born but increases your risk for type 2 diabetes later in life.

Is there a cure for diabetes?

There isn’t a cure yet for diabetes, but losing weight, eating healthy food, and being active can really help. Taking medicine as needed, getting diabetes self-management education and support, and keeping health care appointments can also reduce the impact of diabetes on your life.

Does prediabetes raise your risk for diabetes?

What’s more, more than 84% of them don’t know they have it. With prediabetes, blood sugar levels are higher than normal, but not high enough yet to be diagnosed as type 2 diabetes. Prediabetes raises your risk for type 2 diabetes, heart disease, and stroke.

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Overview

A condition results from insufficient production of insulin, causing high blood sugar.
Condition Highlight
Urgent medical attention is usually recommended in severe cases by healthcare providers
Condition Highlight
May be dangerous or life threatening
How common is condition?
Very common (More than 3 million cases per year in US)
Is condition treatable?
Treatable by a medical professional
Does diagnosis require lab test or imaging?
Requires lab test or imaging
Condition Highlight
Family history may increase likelihood
Condition Image

Symptoms

Causes

Risk Factors

Complications

  • Type 2 diabetes is an impairment in the way the body regulates and uses sugar (glucose) as a fuel. This long-term (chronic) condition results in too much sugar circulating in the bloodstream. Eventually, high blood sugar levels can lead to disorders of the circulatory, nervous and immune systems. In type 2 diabetes, there are primarily two interrel...
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Prevention

  • Signs and symptoms of type 2 diabetes often develop slowly. In fact, you can be living with type 2 diabetes for years and not know it. When signs and symptoms are present, they may include: 1. Increased thirst 2. Frequent urination 3. Increased hunger 4. Unintended weight loss 5. Fatigue 6. Blurred vision 7. Slow-healing sores 8. Frequent infections 9. Numbness or tingling in the hands …
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Overview

  • Type 2 diabetes is primarily the result of two interrelated problems: 1. Cells in muscle, fat and the liver become resistant to insulin. Because these cells don't interact in a normal way with insulin, they don't take in enough sugar. 2. The pancreas is unable to produce enough insulin to manage blood sugar levels. Exactly why this happens is unknown, but being overweight and inactive are …
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Signs and symptoms

  • Factors that may increase your risk of type 2 diabetes include: 1. Weight.Being overweight or obese is a main risk. 2. Fat distribution.Storing fat mainly in your abdomen — rather than your hips and thighs — indicates a greater risk. Your risk of type 2 diabetes rises if you're a man with a waist circumference above 40 inches (101.6 centimeters) or a woman with a measurement above 35 i…
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Causes

  • Type 2 diabetes affects many major organs, including your heart, blood vessels, nerves, eyes and kidneys. Also, factors that increase the risk of diabetes are risk factors for other serious chronic diseases. Managing diabetes and controlling your blood sugar can lower your risk for these complications or coexisting conditions (comorbidities). Potential complications of diabetes and …
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Pathophysiology

  • Healthy lifestyle choices can help prevent type 2 diabetes, and that's true even if you have biological relatives living with diabetes. If you've received a diagnosis of prediabetes, lifestyle changes may slow or stop the progression to diabetes. A healthy lifestyle includes: 1. Eating healthy foods.Choose foods lower in fat and calories and higher in fiber. Focus on fruits, vegeta…
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Diagnosis

Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Symptoms may also include increased hunger, feeling tired, and sores that do not heal. Often symptoms come on slowly. Long-term complications from high blood sugar include heart disease, strokes, diabeti…

Screening

The classic symptoms of diabetes are frequent urination (polyuria), increased thirst (polydipsia), increased hunger (polyphagia), and weight loss. Other symptoms that are commonly present at diagnosis include a history of blurred vision, itchiness, peripheral neuropathy, recurrent vaginal infections, and fatigue. Other symptoms may include loss of taste. Many people, however, have no symptoms during the first few years and are diagnosed on routine testing. A small number of pe…

Prevention

The development of type 2 diabetes is caused by a combination of lifestyle and genetic factors. While some of these factors are under personal control, such as diet and obesity, other factors are not, such as increasing age, female sex, and genetics. Obesity is more common in women than men in many parts of Africa. The nutritional status of a mother during fetal development may also play a role, with one proposed mechanism being that of DNA methylation. The intestinal bacteria Prevotella …

Management

Type 2 diabetes is due to insufficient insulin production from beta cells in the setting of insulin resistance. Insulin resistance, which is the inability of cells to respond adequately to normal levels of insulin, occurs primarily within the muscles, liver, and fat tissue. In the liver, insulin normally suppresses glucoserelease. However, in the setting of insulin resistance, the liver inappropriately releases glucose into the blood. The proportion of insulin resistance versus beta cell dysfunctio…

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