What is the first-line antipsychotic drug?
There is no first-line antipsychotic drug that is suitable for all patients and the properties of individual antipsychotic drugs should be considered and discussed with the patient or carers when prescribing.
What is the recommended treatment for schizophrenia?
Antipsychotics. Antipsychotics are usually recommended as the initial treatment for the symptoms of an acute schizophrenic episode. They work by blocking the effect of the chemical dopamine on the brain.
Is clozapine a first-line treatment?
As a first‐ or second‐line treatment option clozapine outperforms other antipsychotics in schizophrenia spectrum disorders. Compared to first‐line risperidone, clozapine is more effective in schizophrenia spectrum disorders.
Which class of antipsychotic medications is considered first-line therapy for schizophrenia?
According to the American Psychiatric Association, second-generation (atypical) antipsychotics (SGAs)—with the exception of clozapine—are the agents of choice for first-line treatment of schizophrenia. Clozapine is not recommended because of its risk of agranulocytosis.
What is the best antipsychotic?
With respect to the incidence of discontinuation, clozapine was the most effective antipsychotic drug, followed by aripiprazole. As with the survival analysis for time to discontinuation, clozapine and aripiprazole were the top ranked.
What theory and treatment options would be most effective in treating schizophrenia?
The most effective treatment for schizophrenia is a combination of using antipsychotic medications and therapeutic and social support.
Why is clozapine not considered a first-line treatment for schizophrenia?
Clozapine is the most effective medication but is not recommended as first-line therapy because it has a high burden of adverse effects, requires regular blood work, and has not outperformed other medications in first-episode patients. Numerous guidelines or algorithms for the treatment of schizophrenia are available.
What are the side effects of clozapine?
Clozapine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:drowsiness.dizziness, feeling unsteady, or having trouble keeping your balance.increased salivation.dry mouth.restlessness.headache.
Is chlorpromazine an antidepressant?
Chlorpromazine is a psychiatric medication that belongs to the class of drugs called phenothiazine antipsychotics. It works by helping to restore the balance of certain natural substances in the brain.
Are atypical antipsychotics first-line treatment?
Consequently, atypical antipsychotics are now considered to be the first-line treatment for schizophrenia, with the exception of clozapine, which is considered a second-line agent because of risks associated with its use. This review will discuss the literature on atypical antipsychotic efficacy in psychotic disorders.
What drug is most used for schizophrenia?
Some common ones are: Chlorpromazine (Thorazine) Fluphenazine (Prolixin) Haloperidol (Haldol)...Examples of these medicines include:Paliperidone (Invega Sustenna)Paliperidone palmitate (Invega Trinza)Quetiapine (Seroquel)Risperidone (Risperdal)Ziprasidone (Geodon)More items...•
Is clozapine a first or second generation antipsychotic?
What is clozapine? Second generation antipsychotics (sometimes referred to as 'atypical' antipsychotics) such as clozapine are a newer class of antipsychotic medication than first generation 'typical' antipsychotics. Second generation antipsychotics are effective for the positive symptoms of schizophrenia.