Precautions
a sedative-- chlordiazepoxide, diazepam. This list is not complete and many other drugs may affect cimetidine, or be made less effective when taken at the same time as cimetidine. This includes prescription and over-the-counter medicines, vitamins, and herbal products.
What drugs interact with cimetidine?
Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. It is mainly used in the treatment of heartburn and peptic ulcers.. The development of longer-acting H 2 receptor antagonists with fewer drug interactions and adverse effects, such as ranitidine and famotidine, decreased the use of cimetidine, and though it ...
Why is cimetidine a basic drug?
Does CIMETIDINE Interact with other Medications? These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications may interact and cause very harmful effects.
Can I take my medications with cimetidine?
If experienced, these tend to have a Less Severe expression i
- drowsiness
- dizziness
- a skin rash
- nausea
- vomiting
- diarrhea
What are the side effects of cimetidine 400 mg?
How long can you take cimetidine?
The recommended dosage for treating peptic ulcers in adults is 300 to 400 mg twice daily or 800 mg at bedtime for up to eight weeks. The maintenance dosage of cimetidine is 400 mg per day.
How long does it take for cimetidine to start working?
Cimetidine is rapidly and virtually completely absorbed from the gastro-intestinal tract. Absorption is little impaired by food or by antacids. Peak plasma concentrations are obtained about an hour after administration on an empty stomach, and about 2 hours after administration with food.
What are long term side effects of cimetidine?
Headache, dizziness, somnolence, diarrhea.
Does cimetidine heal esophagus?
Cimetidine, 800 mg twice daily, is effective in promoting healing of esophageal ulcers and erosions and in providing heartburn relief in patients with symptomatic erosive/ulcerative GERD.
Can cimetidine be taken on an empty stomach?
How to use Cimetidine. Take this medication by mouth with or without food as directed by your doctor. The dosage and length of treatment are based on your medical condition and response to therapy.
Who should not take cimetidine?
liver disease. pain or trouble trying to swallow food. an unusual or allergic reaction to cimetidine, other medicines, foods, dyes, or preservatives. pregnant or trying to get pregnant.
Why was cimetidine taken off the market?
The FDA said the medicines may contain "unacceptable" amounts of N-Nitrosodimethylamine (NDMA), a substance the World Health Organization has classified as a "probable human carcinogen."
When should cimetidine be taken?
It is usually taken once a day at bedtime or two to four times a day with meals and at bedtime. Over-the-counter cimetidine is usually taken once or twice a day with a glass of water. To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn.
Which is safer omeprazole or cimetidine?
Conclusion: Omeprazole 10 mg o.m. is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis.
Does cimetidine cure ulcer?
Continuous treatment with full doses of cimetidine for a year seems to prevent relapse of the majority of ulcers which have healed during treatment; but it does not cure the ulcer disease, since relapse generally occurs quite rapidly when treatment is discontinued.
Can I take Gaviscon with cimetidine?
Cimetidine pre-treatment slightly, but not significantly, increased the time for half the meal and the Gaviscon to empty from the stomach. The results suggest that the mechanism of action of Liquid Gaviscon is not compromised by concurrent H2-antagonist therapy.
Can cimetidine cause high blood pressure?
Intracerebroventricular administration of cimetidine or metiamide (2 mumol/rat) increased the blood pressure and heart rate. It is concluded that the hypotension after i.v. cimetidine is mediated by peripheral mechanisms.
What medications are affected by cimetidine?
Some examples of affected drugs include atazanavir, dasatinib, delavirdine, certain azole antifungals ( such as itraconazole, ketoconazole ), pazopanib, among others. Ask your doctor or pharmacist if any of the medications you take are affected by cimetidine and how to manage this interaction.
How long before eating can you take Cimetidine?
To prevent heartburn, take 1 tablet by mouth with a glass of water right before or up to 30 minutes before eating food or drinking beverages that cause heartburn.
How to use cipridine?
How to use Cimetidine. Take this medication by mouth with or without food as directed by your doctor. The dosage and length of treatment are based on your medical condition and response to therapy. Follow your doctor's instructions carefully.
What medications slow down the removal of other medications from the body?
Examples of affected drugs include metoprolol, propranolol, tacrine, warfarin, zaleplon, calcium channel blockers (such as diltia zem ), tricyclic antidepressants ( such as amitriptyline ), theophylline, among others. ...
Can you take cipridine while pregnant?
Confusion can increase the risk of falling. Cimetidine should be used only when clearly needed during pregnancy.
Can you stop taking cisapride without your doctor's approval?
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: cisapride, dofetilide, epirubicin, ticlopidine, artemether, clopidogrel, lumefantrine, metformin, moclobemide, moricizine, quinidine, silver sulfadiazine.
Can cimetidine cause allergies?
Precautions. Before taking cimetidine, tell your doctor or pharmacist if you are allergic to it; or to other H2 blockers (e.g., famotidine, nizatidine, ranitidine ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
How long does cipetidine help with ulcers?
study, patients with endoscopically confirmed benign gastric ulcer were treated with Cimetidine 300 mg four times a day or with placebo for 6 weeks. Patients were limited to those with ulcers ranging from 0.5 to 2.5 cm in size. Endoscopically confirmed healing at 6 weeks was seen in significantly* more Cimetidine-treated patients than in patients receiving placebo, as shown below:
How long does it take for cipetidine to heal?
Cimetidine Hydrochloride Oral Solution is indicated in: (1) Short-term treatment of active duodenal ulcer. Most patients heal within 4 weeks and there is rarely reason to use Cimetidine at full dosage for longer than 6 to 8 weeks (see Dosage and Administration-Duodenal Ulcer).
How long does it take for cipridine to be absorbed?
Cimetidine is rapidly absorbed after oral administration and peak levels occur in 45 to 90 minutes. The half-life of Cimetidine is approximately 2 hours. Both oral and parenteral (I.V. or I.M.) administration provide comparable periods of therapeutically effective blood levels; blood concentrations remain above that required to provide 80% inhibition of basal gastric acid secretion for 4 to 5 hours following a dose of 300 mg.
How long does cipridine last?
or 400 mg q.i.d.) for 12 weeks. The use of Cimetidine beyond 12 weeks has not been established.
How to report adverse reactions to cipridine?
To report SUSPECTED ADVERSE REACTIONS, contact Pharmaceutical Associates, Inc. at 1-800-845-8210 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Adverse effects reported in patients taking Cimetidine are described below by body system.
How long before cipridine can you give ketoconazole?
Alteration of pH may affect absorption of certain drugs (e.g., ketoconazole). If these products are needed, they should be given at least 2 hours before Cimetidine administration. Additional clinical experience may reveal other drugs affected by the concomitant administration of Cimetidine.
What factors can cause variations in the percentage of patients on cipridine?
Factors such as smoking, duration and severity of disease, gender, and genetic traits may contribute to variations in actual percentages. Trials of other anti-ulcer therapy, whether placebo-controlled, positive-controlled or open, have demonstrated a range of results similar to that seen with Cimetidine.
How often should I take cimetidine?
Cimetidine comes as a tablet and a liquid to take by mouth. It is usually taken once a day at bedtime or two to four times a day with meals and at bedtime. Over-the-counter cimetidine is usually taken once or twice a day with a glass of water.
How long should I take cimetidine before eating?
To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn. Follow the directions on your prescription or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cimetidine exactly as directed.
What to tell your doctor before taking cimetidine?
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
Why is cipridine prescribed?
Why is this medication prescribed? Cimetidine is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome.
How long before cimetidine can you take digoxin?
if you are taking antacids (Maalox, Mylanta, Tums), digoxin (Lanoxin), ketoconazole (Nizoral), or iron salts, take them 2 hours before cimetidine.
What is cipridine used for?
Cimetidine is also used sometimes to treat stress ulcers, hives and itching, and viral warts, and to prevent aspiration pneumonia during anesthesia. Talk to your doctor about the possible risks of using this medication for your condition.
Can you get pregnant while taking cimetidine?
tell your doctor if you have or have ever had human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), or kidney or liver disease. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking cimetidine, call your doctor.
How many drugs interact with cimetidine?
Severe interactions of cimetidine include: Cimetidine has serious interactions with at least 143 different drugs. Cimetidine has moderate interactions with at least 193 different drugs.
What is cipridine used for?
Cimetidine is a prescription medication used as an acid reducer. Cimetidine relieves heartburn associated with acid indigestion and sour stomach. Cimetidine also prevents heartburn associated with acid indigestion and sour stomach brought on by eating or drinking certain foods and beverages. Cimetidine is available under ...
How many drugs does cipridine interact with?
Cimetidine has serious interactions with at least 143 different drugs. Cimetidine has moderate interactions with at least 193 different drugs. Cimetidine has mild interactions with at least 69 different drugs. This information does not contain all possible interactions or adverse effects.
Can antiandrogen cause feminization?
Antiandrogen: may cause feminization and sexual dysfunction in males. Pregnancy and Lactation. Cimetidine use may be acceptable during pregnancy. Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk.
Can you take Tagamet HB if you are allergic to Cimetidine?
This medication contains cimetidine. Do not take Tagamet HB if you are allergic to cimetidine or any ingredients contained in this drug. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
What drugs interact with cimetidine?
This interaction may occur between cimetidine and warfarin ( Coumadin ), a commonly used blood thinning agent.
What is the class of cipridine?
It belongs to a class of drugs called H2 (histamine-2) blockers that also includes ranitidine ( Zantac ), nizatidine ( Axid ), and famotidine ( Pepcid ).
What is the drug tagamet?
Cimetidine (Tagamet) is a drug prescribed for the treatment of GERD, duodenal ulcers, active gastric ulcers, Zollinger Ellison syndrome, heartburn, indigestion; and the prevention of gastrointestinal bleeding.
Does cimetidine help with acid reflux?
Because cimetidine reduces stomach acid, it may reduce the absorption of drugs (for example, ketoconazole [ Nizoral, Extina, Xolegel, Kuric ]) that are best absorbed in acidic conditions. Such drugs should be administered at least 2 hours before the administration of cimetidine.
What are the side effects of cimetidine?
Ask a doctor or pharmacist if cimetidine is safe to use if you have: 1 stomach pain, nausea, and vomiting; 2 trouble swallowing; 3 frequent chest pain; 4 heartburn with wheezing; 5 unexplained weight loss; 6 heartburn lasting longer than 3 months; or 7 liver or kidney disease.
How to use cipridine?
Use Cimetidine (Tagamet) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Use exactly as directed on the label, or as prescribed by your doctor. Cimetidine is usually taken with meals or at bedtime.
What to do if someone overdoses on cipridine?
If you think you or someone else may have overdosed on: Cimetidine (Tagamet) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Cimetidine (Tagamet), call 911. 911.
Can you breastfeed while taking cimetidine?
liver or kidney disease. Ask a doctor before using this medicine if you are pregnant. You should not breastfeed while using cimetidine.
What is this medicine?
CIMETIDINE (sye MET i deen) is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can relieve ulcer pain and discomfort, and the heartburn from acid reflux.
How should I use this medicine?
Take this medicine by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. If you only take this medicine once a day take it at bedtime. Take your doses at regular intervals. Do not take your medicine more often than directed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your pain does not start to get better or gets worse. You may need to take this medicine for several days before your symptoms get better. Finish the full course of tablets prescribed by your doctor or health care professional even if you feel better.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
What is cipridine used for?
What is Cimetidine? Cimetidine is a drug, available both by prescription and over the counter, to treat heartburn, indigestion, GERD (gastroesophageal reflux disease), ulcers, and related disorders.
What are some alternatives to cimetidine for molluscum?
Alternatives to cimetidine for molluscum include other oral antiviral drugs, topical medications, natural remedies, and minor surgical procedures such as scraping or freezing off the bumps. Laser therapy is another option.
What is the best treatment for molluscum?
An oral medication like cimetidine is preferable to treatments like cryotherapy (burning off molluscum bumps) and laser treatments for molluscum to many people since those treatments can cause pain and scarring. Oral medication is also easier to use than topical medications, which must be carefully applied to each molluscum bump.
Can cimetidine be used for molluscum?
Cimetidine is not a very commonly-prescribed molluscum contagiosum treatment, but sometimes doctors do recommend it. We’ll tell you about the pros and cons of using cimetidine to treat molluscum. We’ll also tell you about some of the alternatives.
Is cimetidine safe for children?
Not everyone should use cimetidine. It is often not recommended for people with immune system problems, kidney problems, liver problems, and some types of lung disease. It is not recommended for children under the age of 12 (and molluscum is most common in children ages 10 and under) and the risk of serious side effects is greater in elderly people. It may not be safe to take if pregnant or breastfeeding.
Can you buy cimetidine over the counter?
Note that we do not recommend using cimetidine to treat molluscum unless advised by your doctor, however. Do not go to the drug store and buy some over the counter and treat yourself .
Description
Cimetidine is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems caused by too much stomach acid (such as Zollinger-Ellison syndrome, erosive esophagitis) or a backward flow of stomach acid into the esophagus (acid reflux disease/GERD).
May Treat: Gastroesophageal reflux disease · Gastric ulcer · Dyspepsia · Zollinger-Ellison syndrome · Duodenal ulcer and more
Brand Names: Tagamet · Tagamet HB · Acid Reducer (cimetidine) · Acid Relief (cimetidine) · Heartburn 200
Drug Class: Gastric Acid Secretion Reducer - Histamine H2-Receptor Antagonists
Availability: Prescription sometimes needed
Pregnancy: Consult your doctor
May Treat: Gastroesophageal reflux disease · Gastric ulcer · Dyspepsia · Zollinger-Ellison syndrome · Duodenal ulcer and more
Brand Names: Tagamet · Tagamet HB · Acid Reducer (cimetidine) · Acid Relief (cimetidine) · Heartburn 200
Drug Class: Gastric Acid Secretion Reducer - Histamine H2-Receptor Antagonists
Availability: Prescription sometimes needed
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
- Tell doctor your complete medical history
- Review all drugs you are taking with your doctor
- May make you drowsy or dizzy. Drive with caution
- Tell doctor your complete medical history
- Review all drugs you are taking with your doctor
- May make you drowsy or dizzy. Drive with caution
- Limit alcohol consumption and stop using tobacco.
- Avoid caffeine which is in coffee, tea & colas
- Call MD now for heartburn with sweating & dizziness
- Unless MD directs, do not use in kids less than 12
- Call doctor if you are not getting better
Clinical Pharmacology
Indications and Usage
Precautions General
Adverse Reactions
Overdosage
- Cimetidine competitively inhibits the action of histamine at the histamine H 2 receptors of the parietal cells and thus is a histamine H 2receptor antagonist. Cimetidine is not an anticholinergic agent. Studies have shown that Cimetidine inhibits both daytime and nocturnal basal gastric acid secretion. Cimetidine also inhibits gastric acid secretion stimulated by food, histamine, pentaga…
Dosage and Administration
- Cimetidine Hydrochloride Oral Solution is indicated in: (1) Short-term treatment of active duodenal ulcer.Most patients heal within 4 weeks and there is rarely reason to use Cimetidine at full dosage for longer than 6 to 8 weeks (see Dosage and Administration-Duodenal Ulcer). Concomitant antacids should be given as needed for relief of pain. Howeve...
How Supplied
- Symptomatic response to Cimetidine therapy does not preclude the presence of a gastric malignancy. There have been rare reports of transient healing of gastric ulcers despite subsequently documented malignancy. Reversible confusional states (see Adverse Reactions) have been observed on occasion, predominantly, but not exclusively, in severely ill patients. Adv…
Package/Label Principal Display Panel
- To report SUSPECTED ADVERSE REACTIONS, contact Pharmaceutical Associates, Inc. at 1-800-845-8210 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Adverse effects reported in patients taking Cimetidine are described below by body system. Incidence figures of 1 in 100 and greater are generally derived from controlled clinical studies. Gastrointestinal Diarrhea (usually …
Medical uses
- Studies in animals indicate that toxic doses are associated with respiratory failure and tachycardia that may be controlled by assisted respiration and the administration of a beta-blocker. Reported acute ingestions orally of up to 20 grams have been associated with transient adverse effects similar to those encountered in normal clinical experience. The usual measures …
Usage
- Duodenal Ulcer Active Duodenal Ulcer:Clinical studies have indicated that suppression of nocturnal acid is the most important factor in duodenal ulcer healing (see Clinical Pharmacology-Antisecretory Activity-Acid Secretion). This is supported by recent clinical trials (see Clinical Pharmacology-Clinical Trials Duodenal Ulcer-Active Duodenal Ulcer). Therefore, there is no appa…
Administration
- Cimetidine Hydrochloride Oral Solution is supplied as a clear, light orange, berry flavored solution containing 300 mg of Cimetidine per 5 mL (teaspoonful) supplied in the following: NDC 0121-0649-08: 8 fl oz (237 mL) bottle NDC 0121-0649-16: 16 fl oz (473 mL) bottle Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature]. Dispense in a tight, light-resistant contai…
Diet
- NDC 0121-0649-08 Cimetidine Hydrochloride Oral Solution 300 mg/5 mL* Rx ONLY 8 fl oz (237 mL) Pharmaceutical Associates, Inc. Greenville, SC 29605
Side effects
- Cimetidine is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome. Over-the-counter cimetidine is used to prevent and treat sympto...
Prevention
- Cimetidine comes as a tablet and a liquid to take by mouth. It is usually taken once a day at bedtime or two to four times a day with meals and at bedtime. Over-the-counter cimetidine is usually taken once or twice a day with a glass of water. To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn. Follow the directions on your pres…
Preparation
- Do not take over-the-counter cimetidine for longer than 2 weeks unless your doctor tells you to. If symptoms of heartburn, acid indigestion, or sour stomach last longer than 2 weeks, stop taking cimetidine and call your doctor.