Treatment FAQ

what is chemotherapy primary treatment for

by Dr. Aimee McLaughlin Published 3 years ago Updated 2 years ago
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As a primary treatment, chemotherapy is used for some cancers such as Hodgkin disease, leukemia, Burkitt's lymphoma, localized diffuse large cell lymphoma, Wilms' tumor, small cell lung cancer, and testicular cancer.

What is chemotherapy mainly used for?

Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available. Chemotherapy drugs can be used alone or in combination to treat a wide variety of cancers.Mar 22, 2022

What conditions are treated with chemotherapy?

Chemotherapy is sometimes used to treat diseases other than cancers....Some long-lasting and late-developing effects of chemo can include:Lung, heart, and kidney problems.Infertility.Nerve damage, called peripheral neuropathy.A higher chance of getting a second cancer.Jun 7, 2020

What is the primary treatment for cancer?

Any cancer treatment can be used as a primary treatment, but the most common primary cancer treatment for the most common types of cancer is surgery. If your cancer is particularly sensitive to radiation therapy or chemotherapy, you may receive one of those therapies as your primary treatment.Jun 4, 2020

What is chemotherapy used for other than cancer?

Chemotherapy is a widely used class of drugs to treat many different disorders including, but not limited to: cancers, blood disorders, and a plethora of autoimmune diseases. Similarly it can be administered in many different forms: intravenously, topically, injected, or received orally.

Is chemotherapy painful?

Does chemotherapy hurt? IV chemotherapy should not cause any pain while being administered. If you experience pain, contact the nurse taking care of you to check your IV line. An exception would be if there is a leak and the drug gets into surrounding tissues.Dec 9, 2019

What is the success rate of chemotherapy?

Around 13% of lung cancers are small-cell. Most people with this type receive chemotherapy. Approximately 83% of lung cancers are N-SC....Lung cancer.N-SC lung cancer stageSurgery plus chemo and/or radiotherapy16%7%Chemo alone1%18%Chemo plus radiotherapy without surgery6%35%Total24%60%1 more row

What's the difference between primary and secondary cancer?

A primary cancer is where a cancer starts. Sometimes cancer cells can break away from the primary cancer and settle and grow in another part of the body. This new cancer growth is called secondary cancer. Secondary cancers are also called metastases.

What is primary chemoradiation?

Chemoradiation therapy is the primary treatment for patients with stage IIB-IVA disease. The success of treatment depends on a careful balance between external beam (EBRT) and brachytherapy that optimizes the dose to the tumor and normal tissues and on the overall duration of treatment.

Is primary cancer curable?

When they are first diagnosed, these cancers have already spread beyond the site where they started. This means that the types of treatments that are most likely to be successful, such as surgery or radiation therapy, are not likely to result in a cure in most cases.Mar 9, 2018

Which cancer has the lowest survival rate?

The cancers with the lowest five-year survival estimates are mesothelioma (7.2%), pancreatic cancer (7.3%) and brain cancer (12.8%). The highest five-year survival estimates are seen in patients with testicular cancer (97%), melanoma of skin (92.3%) and prostate cancer (88%).May 25, 2021

Can cancer spread while on chemo?

While chemotherapy is one of the oldest and most successful ways of treating cancer, it doesn't always work. So, yes, cancer can spread during chemotherapy. Spreading could mean the tumor keeps growing, or that the original tumor shrinks, but cancer metastasizes, forming tumors in other areas of the body.Dec 7, 2021

What is the next treatment after chemotherapy?

Maintenance therapy is the treatment of cancer with medication, typically following an initial round of treatment. Maintenance treatment may include chemotherapy, hormonal therapy, or targeted therapy.

What is chemo for cancer?

Chemotherapy for a Cancer of Unknown Primary. Chemotherapy (chemo) is the use of drugs to treat cancer. Often, these drugs are injected into a vein (IV) or taken by mouth. They enter the bloodstream and reach throughout the body, making this treatment potentially useful for cancers that have spread beyond the organ they started in.

Why is chemo important?

Because chemo reaches all parts of the body, it can sometimes be useful for cancers of unknown primary, as it may help kill cancer cells in areas where they haven’t been detected. Chemo can be used in a number of situations for cancer of unknown primary (CUP). If your doctor recommends chemo, it’s important that you understand what the goals ...

What is the treatment for neuroendocrine carcinoma?

Neuroendocrine carcinomas that are poorly differentiated are often treated with the same chemo as is used for small cell cancer of the lung: a platinum drug (cisplatin or carboplatin) and etoposide.

What cancers are treated like well differentiated tumors?

These patients are treated like patients with well-differentiated carcinoid tumor, with drugs combinations such as: More information about the treatment of well-differentiated neuroendocrine cancers can be found in Gastrointestinal Carcinoid Tumors, Lung Carcinoid Tumor, and Pancreatic Cancer.

What are the side effects of chemo?

Common side effects of chemo include: Hair loss. Mouth sores. Loss of appetite. Diarrhea. Nausea and vomiting. Increased chance of infections (from a shortage of white blood cells)

Is chemo given in combination?

Chemo drugs are often given in combinations, which are more likely to be effective than giving a single drug alone. Which chemo drugs are used depends on the type of cancer.

Does chemotherapy help cancer?

Chemo may be the main treatment for cancers that are clearly advanced and are unlikely to be helped by local treatments such as surgery or radiation therapy. In some cases, it may be very effective in making tumors shrink or even go away altogether.

What is chemo used for?

More often, chemo is used with surgery or radiation therapy or both. And it's sometimes used with other drugs, such as targeted therapy, hormone therapy, or immunotherapy. For example, chemo may be used... To shrink a tumor before surgery or radiation therapy. Chemo used in this way is called neoadjuvant therapy.

What is the treatment for cancer?

There are also other drugs that are used to treat cancer in different ways, including targeted therapy, hormone therapy, and immunotherapy.

How often is chemo given?

Chemotherapy is commonly given at regular intervals called cycles. A cycle may be a dose of one or more drugs on one or more days, followed by several days or weeks without treatment. This gives normal cells time to recover from drug side effects. Sometimes, doses may be given a certain number of days in a row, or every other day for several days, followed by a period of rest. Some drugs work best when given continuously over a set number of days.

What is the term for the use of drugs to treat cancer?

Chemotherapy refers to the use of any drug to treat any disease. But to most people, the word chemotherapy ( or "chemo") means drugs used for cancer treatment. It's important to know that not all medicines and drugs to treat cancer work the same way. It used to be that the only kind of drug that could treat cancer was traditional or standard chemo, ...

Why do people need chemo?

When the cancer is at an advanced stage, probably cannot be controlled, and has spread, the goal of giving chemo may be to improve the quality of life or help the person feel better. For instance, chemo may be used to help shrink a tumor that’s causing pain or pressure so the patient feels better and has less pain.

What is radiation therapy?

Surgery removes a tumor from a part of the body where cancer has been found, and radiation therapy is aimed at a certain area of the body to kill or damage cancer cells. Treatments like these are called local treatments because they affect one part of the body.

Can chemo cause cancer?

Most chemotherapy (chemo) drugs are strong medicines that have a fairly narrow range for dose safety and effectiveness. Taking too little of a drug will not treat the cancer well and taking too much may cause life-threatening side effects. For this reason, doctors must calculate chemo doses very carefully.

How often do you have chemotherapy?

Each cycle of treatment varies depending on what you are having. But usually, it’s every 2 to 4 weeks.

What are some examples of chemotherapy for CUP?

Examples of chemotherapy for CUP include: carboplatin and paclitaxel. gemcitabine and carboplatin or cisplatin. epirubicin, cisplatin and capecitabine (ECX) epirubicin, cisplatin and fluorouracil (ECF) irinotecan and gemcitabine or oxaliplatin. You might have other types of chemotherapy if you have cancer spread that is similar to other types ...

What is the name of the cancer cells that make sperm in the testicles?

These are called extragonadal germ cell tumours . You usually have a combination of chemotherapy that includes the drugs cisplatin or carboplatin.

What is the treatment for CUP?

There are a number of chemotherapy drugs used to treat CUP. The type of drug you have depends on different factors such as: the results of all your tests. the side effects of the drugs. your general health and fitness. whether you have other medical problems such as heart problems.

What is the number to call for chemo?

Tell your doctor or nurse about any problems or side effects that you have. The nurse will give you telephone numbers to call if you have any problems at home. If you have any questions about chemotherapy, you can talk to Cancer Research UK's information nurses on freephone 0808 800 4040, 9am to 5pm, Monday to Friday.

Can you bring a friend to chemo?

You can usually bring a friend or family member with you. You have some types of chemotherapy over several days. You might be able to have some drugs through a small portable pump that you take home. For some types of chemotherapy you have to stay in a hospital ward.

Can chemo cure cancer?

The drugs circulate throughout the body in the bloodstream. Cancer of unknown primary (CUP) is an advanced cancer. This means that unfortunately, it cannot be cured. The aim of treatment is generally to relieve symptoms rather than cure the cancer.

How to help someone with chemotherapy?

Make a caregiving plan. People receiving chemotherapy may need extra help during treatment with transportation, household chores, and other tasks. Family and friends can provide valuable support during this time, called caregiving. Ask your team what type of caregiving at home you may need during and after treatment.

How is chemo given?

The most common way that chemotherapy drugs are given is through a needle into a vein. This is called intravenous or IV chemotherapy. Chemotherapy can also be taken as a pill, capsule, or liquid by mouth, as an injection or shot, or as a cream that is put directly on your skin.

How long does chemo last?

Most chemotherapy treatments are given in repeating cycles. The length of a cycle depends on the drug (s) you receive. Most cycles range from 2 to 6 weeks. The number of treatment doses scheduled within each cycle also depends on the prescribed chemotherapy.

What type of doctor is best for cancer?

Medical oncologist. This type of doctor specializes in treating cancer with medication. Your medical oncologist works closely with other team members to create your overall cancer treatment plan. They also lead your chemotherapy treatments.

How to get a blood test for cancer?

Have a blood sample taken. Meet with your oncologist so they can check your health and blood test results. Meet the nurse or other health professionals who will give your treatment. Have your blood pressure, pulse, breathing, and temperature taken before starting treatment.

What to tell your chemo team?

Always tell your chemotherapy team about any prescription and non-prescription medicines you take. Include vitamins and other supplements, such as herbs. This is to avoid drug interactions and other unwanted side effects. Your doctor will tell you if you should not take them during chemotherapy.

What is the best treatment for cancer?

Relieving physical and emotional side effects is an important part of your overall cancer treatment. This type of care is called palliative care or supportive care . Talk with your health care team about the side effects you experience and ways to manage and treat them. Learn more about the side effects of chemotherapy.

What is neoadjuvant chemotherapy?

Neoadjuvant chemotherapy means that chemo takes place before the main treatment. The goal is to improve the likelihood that the main treatment, usually surgery or radiation therapy, will be successful. As with adjuvant chemotherapy, there are many factors involved in choosing the timing of neoadjuvant chemo.

What is adjuvant treatment?

In addition to chemotherapy, adjuvant treatments can include: Hormone therapy is often used for hormone receptor positive cancers. Immunotherapy may be used to help your immune system recognize and fight cancer cells. Radiation therapy can help target a particular tumor or organ.

Can chemo shrink a tumor?

Chemo may be able to shrink the tumor first so it’s less risky to remove. There’s a chance that cancer cells have broken away from the primary tumor. Any complications from surgery can delay the start of adjuvant chemo. Starting with chemo can prevent tumors from developing in distant organs.

Can you get chemo for stage 2 colon cancer?

But not all people with stage 2 colon cancer get the same benefit. In stage 2 colon cancer, the use of adjuvant chemo may depend on certain biomarkers. All these factors must be considered when deciding if adjuvant chemo is likely to be beneficial.

Is chemo a neoadjuvant?

As with adjuvant chemotherapy, there are many factors involved in choosing the timing of neoadjuvant chemo. Your doctor might recommend neoadjuvant chemotherapy in the following situations: The primary tumor is large or pressing on vital organs, which can make surgery complicated and risky. Chemo may be able to shrink the tumor first so it’s less ...

Can you have chemotherapy with a specific type of cancer?

Your doctor may recommend adjuvant chemotherapy if: you have a particular type of cancer or carry certain biomarkers that are known to respond well to chemotherapy drugs. you carry specific genetic mutations that carry a high risk of cancer recurrence. during surgery, cancer cells were found in your lymph nodes.

Can cancer cells be found in the lymphatic system?

It’s also possible that cancer cells may be circulating in your bloodstream or lymphatic system. The traveling cancer cells don’t show up on imaging tests. Without treatment, they can find their way to distant organs to form new tumors. Chemotherapy is a systemic treatment.

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Overview

  • Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body.Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body.Many different chemotherapy drugs are available. Chemotherapy drugs can be used alone or in combination to treat a wide variety of cancers.Tho…
See more on mayoclinic.org
  • Hair loss often begins around the time of your second chemotherapy infusion, though this varies widely. It may start slowly, but increases rapidly around 1 month to 2 months after starting treatment. Some people do not lose all of their hair until they have nearly completed chemotherapy. Hair re-growth typically begins within 3 months of concluding chemotherapy. Wh…
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Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.
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Treatment

  • Some chemotherapy drugs result in only minimal hair loss, though these are often combined with drugs that cause more hair loss. These include: Some of the targeted therapies that have been linked with hair changes include: There are a number of non-cancer related medications that are associated with hair loss, that might accentuate the effects of chemotherapy drugs if used in co…
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  • Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs …
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  • Each therapy works differently and serves a different purpose. Not every medication will be right for everyone. Which therapy is right for you will depend on various factors including the type of cancer youre fighting, the severity of your case, and other health considerations.
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Side Effects

  • Some women with breast cancer have developed permanent hair loss following a combination of taxanes (such as Taxol or Taxotere) and hormonal therapy, though this is rare. There have also been a few reported cases of permanent and severe hair loss in women with breast cancer who have received a combination of FEC (fluorouracil/epirubicin/cyclophosphamide) with docetaxel.
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  • You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemot…
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  • Side effects for breast cancer oral chemotherapy drugs are similar to those for traditional chemotherapy. They include:
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  • Side effects of chemotherapy can include: 1. Nausea 2. Vomiting 3. Loss of appetite 4. Malnutrition 5. Hair loss 6. Bleeding or damage to the heart, liver or kidneysChemotherapy can weaken the body's immune system. This can make a person more likely to get sick. Improvements in chemotherapy include new drugs that cause fewer side effects. Other drugs can help control …
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Risks

  • Side effects of chemotherapy drugs can be significant. Each drug has different side effects, and not every drug causes every side effect. Ask your doctor about the side effects of the particular drugs you'll receive.
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  • It can be very emotional coping with the hair loss you experience during chemotherapy. Even though this complication is more of a nuisance, it remains one of the most feared side effects. Many oncologists recommend that you purchase a wig, hats, or scarves before beginning chemotherapy. All or a portion of the cost of a wig may be covered by your insurance. To have it …
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  • You should also ask your doctor whether its safe to use a pill organizer. Chemotherapy pills should be considered hazardous, according to Mayo Clinic. So you need to keep them in the container they came in and cant store them with other medications or supplements. You should also avoid crushing, breaking, or chewing oral chemotherapy pills. The American Cancer Societ…
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Results

  • You'll meet with your cancer doctor (oncologist) regularly during chemotherapy treatment. Your oncologist will ask about any side effects you're experiencing, since many can be controlled.Depending on your situation, you may also undergo scans and other tests to monitor your cancer during chemotherapy treatment. These tests can give your doctor an idea of how yo…
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  • Dont make any changes to your doses unless your doctor explicitly tells you to. Even if you begin to feel better, your body needs the chemo to continue to fight the growth of cancer cells. Your doctor will request blood tests and other scans to monitor changes in the cancer and make any necessary adjustments to your treatment plan.
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  • Figure 4 displays the density distribution of the synergy scores based on the Loewe model. The values range from −326 to 179. The median and the standard deviation of the distribution are 4.37 and 22.89, respectively. By definition all synergy scores above zero are synergistic. However, drug combinations exhibiting a highly synergistic effect are attractive candidates for clinical studies. …
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Preparation

  • How you prepare for chemotherapy depends on which drugs you'll receive and how they'll be administered. Your doctor will give you specific instructions to prepare for your chemotherapy treatments. You may need to: 1. Have a device surgically inserted before intravenous chemotherapy. If you'll be receiving your chemotherapy intravenously — into a vein — your docto…
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  • Unlike traditional chemotherapy treatment given at a clinic or hospital, chemotherapy pills are taken at home. Your doctors will provide you with clear instructions on how to take your medication and when. Theyll also tell you whether you should take the pills with food and how long or before after eating. Its very important to follow these instructions exactly. In some cases…
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What You Can Expect

  • Your doctor chooses which chemotherapy drugs you'll receive based on several factors, including: 1. Type of cancer 2. Stage of cancer 3. Overall health 4. Previous cancer treatments 5. Your goals and preferencesDiscuss your treatment options with your doctor. Together you can decide what's right for you.
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  • Most of the time, these drugs come in two forms: 1. Intravenous (IV) 2. PillThe doctor must find out the amount and type of drug that works best for each patient. It can take one or more treatments to find the right balance. If too little of the drug is given, the tumor might not shrink. If too much is given, the drugs may be too hard on the patient’s body. A personal plan will find the …
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Cost

  • Scalp cooling units can reduce roughly 50 percent of hair loss, but comes with a price. Many infusion centers do not have these units and therefore you may have to rent a cooling device, and depending on the device, this can be fairly pricey.
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Benefits

  • One of the primary benefits of breast cancer chemotherapy pills is their convenience. You can take them at home. You dont have to allot extra time for traveling to and from the clinic and receiving treatment. Also, because oral chemotherapy is significantly less invasive than traditional chemotherapy, which involves IVs that are painful for some, its a more comfortable option. Oral …
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Symptoms

  • The newer targeted therapies for cancer don't usually cause total hair loss like chemotherapy drugs, but can result in changes such as thinning of the hair and dryness, as well as changes in texture similar to the chemo curls noted above. Some targeted therapies may also affect the pigmentation of hair, often causing the hair to become darker.
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