Precautions
Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medication, even months after stopping. The risk of liver problems is highest in adults between the ages of 35 and 65.
What happens when you stop taking isoniazid?
a history of severe allergic reaction to isoniazid; a history of hepatitis or other liver problems caused by taking isoniazid; or. a history of severe isoniazid side effects such as fever, chills, or joint pain and swelling.
What are the signs and symptoms of isoniazid toxicity?
Follow your doctor's instructions carefully when taking this medicine. Don't use more or less isoniazid than is recommended. Sometimes, therapy with isoniazid must be continued for a long period of time (6 to 12 months).
How long should I take isoniazid?
Isoniazid is an antibiotic and works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu ).
What is the mechanism of action of isoniazid?
What happens after finishing TB treatment?
Once your course of treatment is finished, you may have tests to make sure you are clear of TB. You might need more treatment if tests show there is still TB bacteria in your body, but most people will get the all-clear. Your treatment will not be stopped until you are cured.
How do you know if you have TB after treatment?
Even after you finish taking all of your TB medicine, your TB skin test or TB blood test will still be positive. Ask your healthcare provider to give you a written record that says your test was positive and that you finished treatment.
Does latent TB go away after treatment?
If they did receive treatment, their test may stay “positive” or “reactive” but it doesn't mean they need to be treated again unless they are exposed to tuberculosis again.
How long is TB active after treatment?
After taking antibiotics for 2 weeks, most people are no longer infectious and feel better. However, it's important to continue taking your medicine exactly as prescribed and to complete the whole course of antibiotics. Taking medication for 6 months is the best way to ensure the TB bacteria are killed.
Can tuberculosis be completely cured?
With treatment, TB can almost always be cured. A course of antibiotics will usually need to be taken for 6 months. Several different antibiotics are used because some forms of TB are resistant to certain antibiotics.
Can I gain weight after TB treatment?
Overall, patients had a significant change in weight over the course of treatment (p < 0.0001). After 2 months of treatment, 31.9% of patients had gained at least 5% body weight; by the end of treatment, 62.4% of patients had gained at least 5% weight.
How do you know if latent TB is active?
Persons with latent TB infection do not feel sick and do not have any symptoms. They are infected with M. tuberculosis, but do not have TB disease. The only sign of TB infection is a positive reaction to the tuberculin skin test or TB blood test.
Does isoniazid cure latent TB?
Isoniazid and Rifapentine (INH-RPT) are medicines used together to treat LTBI. They kill the sleeping TB germs before they make you sick. It can take many months for the medicine to kill the TB germs because they are strong.
Is latent TB Serious?
In the United States, up to 13 million people may have latent TB infection. Without treatment, on average 1 in 10 people with latent TB infection will get sick with TB disease in the future. The risk is higher for people with HIV, diabetes, or other conditions that affect the immune system.
How long should TB patients be isolated?
Note: Home isolation is recommended for the initial three to five days of appropriate four-drug TB treatment.
Does TB stay in your body forever?
Many people who have latent TB infection never develop TB disease. In these people, the TB bacteria remain inactive for a lifetime without causing disease. But in other people, especially people who have a weak immune system, the bacteria become active, multiply, and cause TB disease.
Which food is not good for TB patients?
As a TB patient, you must avoid caffeine, refined sugar and flour, sodium, and bottled sauces. Foods containing saturated and trans fats worsen the TB symptoms of diarrhoea and abdominal cramping and fatigue. Additionally, alcohol and tobacco are a definite no-no during the disease treatment and cure phase.
Before Taking This Medicine
You should not use isoniazid if you are allergic to it, or if you have: 1. active liver disease; 2. a history of severe allergic reaction to isonia...
How Should I Take Isoniazid?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.Take isonia...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include vomiting, severe dizziness or drowsin...
What Should I Avoid While Taking Isoniazid?
Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid.You may need to avoid certain foods while you are...
What Other Drugs Will Affect Isoniazid?
Many drugs can interact with isoniazid. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible...
How to take medicine at the same time?
Ask a family member or friend to remind you. Use a pillbox. Put a reminder note on your mirror or refrigerator. Use a calendar to check off the day when you take your medicine.
How to treat latent TB?
Go to your planned clinic visits. Discuss any alcohol use with your doctor. Alcohol use may cause side effects. Tell your doctor about all other medicines you are taking. Be sure to tell your other doctors that you are being treated for latentTB infection.
How to take a pill?
Tips to Help You Take Your Medicine: 1 Take your medicine at the same time every day. 2 Set an alarm reminder for the time you should take your medicine. 3 Ask a family member or friend to remind you. 4 Use a pillbox. 5 Put a reminder note on your mirror or refrigerator. 6 Use a calendar to check off the day when you take your medicine.
How long should I take isoniazid?
Take isoniazid on an empty stomach, at least 1 hour before or 2 hours after a meal. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
How do you know if you have isoniazid?
This reaction may occur several weeks after you began using isoniazid. Call your doctor at once if you have:
What is isoniazid used for?
Isoniazid is an antibiotic that fights bacteria. Isoniazid is used to treat and to prevent tuberculosis (TB). You may need to take other TB medicines in combination with isoniazid. When treating active TB, isoniazid must be used with other TB medicines. Tuberculosis can become resistant to treatment if isoniazid is used alone.
What are the side effects of a syringe?
Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or. abnormal liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Can isoniazid cause liver problems?
Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medicine, especially if you are between the ages of 35 and 65. Your liver function may need to be checked every month while you are taking this medicine.
Can Isoniazid be used alone?
Tuberculosis can become resistant to treatment if isoniazid is used alone. Take all your medicines as prescribed by your doctor. Isoniazid may also be used for purposes not listed in this medication guide. 510790083_PB. oval, white, imprinted with b, 071 300. Isoniazid 100 mg-VER.
Is isoniazid safe for kidneys?
a history of severe isoniazid side effects such as fever, chills, or joint pain and swelling. To make sure isoniazid is safe for you, tell your doctor if you have: a history of liver disease; kidney disease; nerve problems that cause pain, weakness, or numbness; diabetes; HIV or AIDS;
Does isoniazid cause side effects?
Side effects requiring immediate medical attention. Along with its needed effects, is oniazid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Does isoniazid increase the risk of hepatitis?
The risk for hepatitis increases with advancing age, concomitant alcohol use, chronic liver disease, and injection drug use. Patients given isoniazid should be carefully monitored and interviewed at monthly intervals.
Does isoniazid need medical attention?
Side effects not requiring immediate medical attention. Some side effects of isoniazid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Can isoniazid cause hepatitis?
Severe and sometimes fatal hepatitis has been reported with is oniazid therapy and may occur even after many months of treatment. The risk for hepatitis increases with advancing age, concomitant alcohol use, chronic liver disease, and injection drug use. Patients given isoniazid should be carefully monitored and interviewed at monthly intervals. For persons 35 and older, in addition to monthly symptom reviews, hepatic enzymes (specifically, AST and ALT (formerly SGOT and SGPT, respectively) should be measured prior to starting isoniazid therapy and periodically throughout treatment. An increased risk of fatal hepatitis associated with isoniazid has been reported in women, particularly black and Hispanic women. The risk may also be increased during the post partum period. More careful monitoring should be considered in these groups, possibly including more frequent laboratory monitoring.
How do you know if you have isoniazid?
Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using isoniazid. Call your doctor at once if you have:
What are the side effects of a syringe?
Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or. abnormal liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Can isoniazid be used alone?
Tuberculosis can become resistant to treatment if isoniazid is used alone. Take all your medicines as prescribed by your doctor. Isoniazid may also be used for purposes not listed in this medication guide.
Can you take isoniazid if you are allergic to it?
You should not use isoniazid if you are allergic to it, or if you have: a history of severe isoniazid side effects such as fever, chills, or joint pain and swelling. To make sure isoniazid is safe for you, tell your doctor if you have: if you have ever had to stop taking isoniazid for any reason.
Can Isoniazid be used for a viral infection?
Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Isoniazid will not treat a viral infection such as the flu or a common cold.
Can isoniazid cause joint pain?
a history of severe is oniazid side effects such as fever, chills, or joint pain and swelling. To make sure isoniazid is safe for you, tell your doctor if you have: a history of liver disease; kidney disease; nerve problems that cause pain, weakness, or numbness; diabetes; HIV or AIDS; if you drink alcohol daily;
Can isoniazid harm a baby?
Ask your doctor about your specific risk. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Talk to your doctor if you will be breast-feeding a baby during your treatment with isoniazid.
How long should I take isoniazid?
You may have to take it every day for as long as 6 months to 2 years. It is important that you do not miss any doses. Your doctor may also want you to take pyridoxine (e.g., Hexa-Betalin, vitamin B 6) every day to help prevent or lessen some of the side effects of isoniazid.
What is isoniazid used for?
Overview TOP. Isoniazid is used to treat tuberculosis (TB) or prevent its return (reactivation). It may be given alone, or in combination with other medicines, to treat TB or to prevent its return (reactivation). This medicine may also be used for other problems as determined by your doctor.
How much does isoniazid cost?
ISONIAZID is used to prevent or to treat tuberculosis (TB). The lowest GoodRx price for the most common version of isoniazid is around $6.92, 66% off the average retail price of $20.81. Compare antimycobacterials. Prescription Settings.
How many times a day should I take a sulfate supplement?
Adults and teenagers—300 mg once a day; or 15 mg per kg (6.8 mg per pound) of body weight, up to 900 mg, two times a week or three times a week, depending on the schedule your doctor chooses for you. Children—Dose is based on body weight.
Can isoniazid cause hepatitis?
Intramuscular route (Solution) Severe and sometimes fatal hepatitis has been reported with isoniazid therapy and may occur even after many months of treatment. The risk for hepatitis increases with advancing age, concomitant alcohol use, chronic liver disease, and injection drug use. Patients given isoniazid should be carefully monitored ...
Can isoniazid cause side effects?
Isoniazid can cause serious side effects in any patient. Therefore, it is especially important that you discuss with the child's doctor the good that this medicine may do as well as the risks of using it.
Can you take tegafur and rifampin together?
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
How to take isoniazid?
How to use Isoniazid. Take this medication by mouth on an empty stomach (1 hour before or 2 hours after meals) as directed by your doctor. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
What is isoniazid used for?
Isoniazid is used with other medications to treat active tuberculosis (TB) infections. It is also used alone to prevent active TB infections in people who may be infected with the bacteria (people with positive TB skin test ). Isoniazid is an antibiotic and works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu ). Using any antibiotic when it is not needed can cause it to not work for future infections.
What to do if side effects persist?
If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Does isoniazid cause blood pressure to increase?
Isoniazid may interact with foods containing tyramine/ histamine (such as cheese, red wine, certain types of fish). This interaction may cause increased blood pressure, flushing of the skin, headache, dizziness, or fast/pounding heartbeat. Tell your doctor right away if any of these symptoms occur.
Does isoniazid work for viral infections?
Isoniazid is an antibiotic and works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu ). Using any antibiotic when it is not needed can cause it to not work for future infections.
Can you take aluminum antacids with a spoon?
Do not use a household spoon because you may not get the correct dose. If you also take antacids that contain aluminum, take this medication at least 1 hour before the antacid. Dosage is based on your age, weight, medical condition, and response to treatment. For the best effect, take this drug at evenly spaced times.
Can drug interactions change your medication?
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Warning
Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some things I need to know or do while I take this drug?
Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
How is this drug best taken?
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
General drug facts
If your symptoms or health problems do not get better or if they become worse, call your doctor.
Consumer Information Use and Disclaimer
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.