When a treatment stops working, the cancer resumes growing or begins cropping up in other places in the body as metastases. Doctors may find this through routine scans or tests that are typically done at scheduled intervals, or the patient may describe new symptoms, as Brickell did, that prompt the doctor to run tests.
Full Answer
Is it time to stop your cancer treatment?
May 13, 2019 · Cancer treatments can help stop cancer from growing or spreading. But sometimes treatment does not work well or stops working. Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing. If this happens, your doctor might say …
How do you know if your cancer treatment is working?
At the moment you are told your treatment isn’t likely to work, you might become silent or feel like you’re not able to listen or focus anymore. You might start crying and feel like you’ll never stop. You might feel completely numb. Or you might feel calm and detached – that happens too.
When stopping chemotherapy is the best option?
Nov 03, 2021 · When a treatment stops working, the cancer resumes growing or begins cropping up in other places in the body as metastases. Doctors may find this through routine scans or tests that are typically done at scheduled intervals, or the patient may describe new symptoms, as Brickell did, that prompt the doctor to run tests.
When chemo no longer works?
Feb 09, 2022 · If one treatment stops working, there usually is another you can try. The cancer can be active sometimes and then go into remission at other times. Many different treatments — alone, in combination, or in sequence — are often used. Breaks in treatment can make a big difference when the disease is under control and you are feeling good.

Why does cancer treatment stopped working?
Resistance can occur when cancer cells—even a small group of cells within a tumor—contain molecular changes that make them insensitive to a particular drug before treatment even begins. Because cancer cells within the same tumor often have a variety of molecular changes, this so-called intrinsic resistance is common.Dec 21, 2016
What does it mean when chemo stops working?
If this happens, your doctor might say your cancer has advanced or progressed. There may or may not be other treatment options. But when many different treatments have been tried and are no longer controlling the cancer, it could be time to weigh the benefits and risks of continuing to try new treatments.May 13, 2019
What are signs that cancer treatment is not working?
Here are some signs that chemotherapy may not be working as well as expected: tumors aren't shrinking. new tumors keep forming. cancer is spreading to new areas.Jul 31, 2019
What happens when cancer treatment ends?
When treatment ends, you may expect life to return to the way it was before you were diagnosed with cancer. But it can take time to recover. You may have permanent scars on your body, or you may not be able to do some things you once did easily. Or you may even have emotional scars from going through so much.
What is the most life threatening side effect of chemotherapy?
Low blood cell counts happen because of chemotherapy's effect on blood cells made in the bone marrow. Blood cell counts often reach their lowest level about 7 to 14 days after chemotherapy. Low blood cell counts is the most common and most serious side effect of chemotherapy.
What happens if chemo doesn't shrink tumors?
In those cases, the patients are very likely to remain cancer-free for life after surgery. But not all tumors shrink under chemotherapy. If the tumor resists neoadjuvant therapy, there can be a higher risk of developing metastatic disease, meaning that the tumor will recur in other organs, such as bones or lungs.Jan 1, 2019
What is Stage 4 cancer life expectancy?
In most cases, how stage 4 cancer is likely to progress (its prognosis) depends on the type of cancer....Survival Rates.Five-Year Survival Rates for Distant (Stage 4) CancerCancer TypeRelative 5-Year Survival RateLeukemia*63.7%Non-Hodgkin lymphoma*63.3%Thyroid54.9%9 more rows•Mar 5, 2022
What are the last stages of cancer?
Patients may have trouble swallowing food and fluids at the end of life. Patients with cancer may have trouble swallowing in the last days of life. Both fluids and food may be hard to swallow, causing a loss of appetite, weight loss and muscle wasting, and weakness.Feb 16, 2022
What is the most common cause of death in cancer patients?
Lung cancer was the leading cause of cancer death, accounting for 23% of all cancer deaths. Other common causes of cancer death were cancers of the colon and rectum (9%), pancreas (8%), female breast (7%), prostate (5%), and liver and intrahepatic bile duct (5%).Feb 28, 2022
What are the signs of cancer coming back?
Common signs of active cancer include:Unexplained weight loss.Fatigue.Fever.Pain.Skin changes.Change in bowl habits or bladder function.Sores that do not heal.Hoarseness or trouble swallowing.More items...
How long can a cancer patient live after treatment?
A health care provider might say, “People with this type of cancer generally have a 60 percent five-year survival rate.” This means that 60 out of 100 people who were treated for this type of cancer during the research studies were still living after five years.
What do you say at the end of chemo?
Many people often say "congratulations" after the person finished chemotherapy, but it may not always be a good thing. Instead of saying "let's celebrate," ask, "how do you feel now that chemo is over?" There are certain stock phrases that people seem to say in tough times, such as "everything happens for a reason."Oct 14, 2014
What happens if cancer stops working?
Or maybe one type of cancer treatment has stopped working and the cancer has kept growing. If this happens, your doctor might say your cancer has advanced or progressed. There may or may not be other treatment options. But when many different treatments have been tried and are no longer controlling the cancer, it could be time to weigh ...
How to trust your doctor about cancer?
Trusting your cancer care team. Talking with your doctor and cancer care team, and trusting them to be honest, open, and supportive, is very important. You will have more confidence in treatment decisions if you trust the doctors making recommendations. This means communication is a key part of your care, from diagnosis throughout treatment ...
How to talk to your loved ones about cancer?
Talking with your loved ones. Be open with your loved ones about your cancer and the news you've been given. Explore their thoughts, feelings, and suggestions. Talk to them about the options you have been given, along with the decisions you have made or are thinking of making. If you feel you need their input, ask.
Is there hope for a life without cancer?
Staying hopeful. Your hope for a life without cancer might not be as bright, but there is still hope for good times with family and friends – times that are filled with happiness and meaning. Pausing at this time in your cancer treatment gives you a chance to refocus on the most important things in your life.
Can cancer shrink?
If you have cancer that keeps growing or comes back after one kind of treatment, it’s possible that another treatment might still help shrink the cancer, or at least keep it in check enough to help you live longer and feel better. Clinical trials also might offer chances to try newer treatments that could be helpful.
Can you get a second opinion on cancer?
When faced with deciding whether to continue cancer treatment, some patients or their loved ones may want to get a second opinion. Even when you place full trust in your doctor and cancer care team, you might wonder if another doctor could offer something else or more information. It's normal to think about talking to someone else, and your doctor should support you if you decide to get another opinion. Remember that your cancer care team wants you to be sure about the decisions you make. You can read more in Seeking a Second Opinion.
Does cancer stop working?
If Cancer Treatments Stop Working. Cancer treatments can help stop cancer from growing or spreading. But sometimes treatment does not work well or stops working. Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing.
Why should I stop chemotherapy?
This may be because of adverse side effects, because the treatment seems to be ineffective, or for other reasons. Anyone who is considering stopping should speak with their doctor first.
What to do if chemotherapy stops working?
If chemotherapy stops working, discuss the other options with the oncologist, the rest of the healthcare team, and loved ones, including family members, before making a decision about treatment going forward . Last medically reviewed on March 1, 2021. Cancer / Oncology.
How does radiation therapy work?
Radiation therapy involves using radiation to kill cancer cells and reduce the size of tumors. It can be a primary treatment, but it also works well with other approaches, such as surgery. Radiation therapy damages the DNA in cancer cells so that they can no longer repair themselves.
How do you know if chemo is not working?
Signs chemo is not working. Signs that a person’s cancer is not responding to chemotherapy include: a tumor growing or not shrinking. cancer spreading to other areas of the body, a process called metastasis. cancer symptoms returning.
How long does radiation treatment last?
It can be inconvenient and time-consuming, as a person needs to have the treatment 5 days a week for up to 2 months. It can be expensive, though the exact cost depends on the type and amount of treatment. The skin around the site of radiation can become red and sore.
How long does it take for a radioactive implant to be removed?
The implants can either be permanent or temporary. Temporary implants are usually removed after a few minutes or days , and the person is considered radioactive until the removal.
Why do doctors do chemo tests?
Doctors do tests at intervals to assess the effectiveness of chemotherapy.
What happens when the Chemotherapy Stops
My brother was diagnosed with Terminal stage 4 oesophageal cancer in March. He is coming up to his 5th ECX infusion next week. The scan after the 3rd infusion showed a small reduction in the size of the cancer.
What happens when the Chemotherapy Stops
Thanks Dave - Glad to hear that your situation is as you state. I appreciate that everyone is different and no-one can give a clear cut vision of the future. My brother, Michael and I discuss how he is at the moment, but don't talk about anything further than the next infusion or event.
What happens when the Chemotherapy Stops
Gosh, same question for us too. My fella has stage 4 stomach cancer, for 6 cycles of EOX, just had 3rd and now waiting of a scan. We only seem talk about the "here and now" although we have sorted out our "affairs"....
What happens when the Chemotherapy Stops
Hi Gemini 23, thanks for your post - Yesterday Michael had his 5th infusion - everything seems to obe going surprisingly well and notwithstanding the possible, even probable outcomes, the mood is one of absolute optimism - lets hope that alls well that ends well and in the meantime, we need to stay supportive and caring - have beautiful wedding - NIck.
What happens when the Chemotherapy Stops
Hello Thanks for the message. Yes we're now married after 23 years and was a huge surprise for everyone!! Loved every minute!! Gosh a lot has happened since my initial post. His mid way scan during EOX showed it hadn't worked as it should of, was a big disappointment after seeing good results ourselves.
What to do if you have cancer?
Counseling and other resources to help with the fear, anxiety, and depression your cancer might cause. Help with health insurance, employment, and legal issues that arise from your cancer and its treatment. Hospice Care. Your doctor might recommend this if your treatments have stopped working and your cancer has spread.
What happens if immunotherapy isn't right for you?
If it turns out that immunotherapy isn’t right for you, the treatment you try next will depend on a few things, including: Your health. Your age. The type of cancer you have. Other treatments you've tried. Side effects the other treatments caused.
Why do scientists use immunotherapy?
Scientists use them to test new ways to treat cancer to see if they’re safe and if they work. A clinical trial gives you a chance to try a new cancer treatment that isn't available to everyone. Many new types of immunotherapy are in clinical trials. Your doctor can let you know if one of these trials might be a good fit.
What are the pros and cons of immunotherapy?
Pros and Cons of Immunotherapy. Immunotherapy Success Rate. Combination Care for Cancer. Immunotherapy Side Effects. Ways to Boost Immune System. When Immunotherapy Stops Working. Immunotherapy is a treatment that helps your body's immune system fight cancer. It's approved to treat certain kinds, including some types of lymphoma, leukemia, ...
What is the best treatment for cancer?
You can get it from a machine that’s outside your body, or a doctor can put it inside your body near the cancer. Chemotherapy.
Can immunotherapy be used for cancer?
It's approved to treat certain kinds, including some types of lymphoma, leukemia, breast cancer, and lung cancer. Your doctor will recommend immunotherapy if it has a good chance of working and it isn't likely to cause a lot of side effects. But it doesn’t work for everyone, and it may cause side effects you can't handle.

If You’Re Generally in Good Health…
- Sometimes when treatment stops working, the patient is actually in very good shape and is eligible for another treatment, so we simply discuss the new treatment. It’s the same as any treatment discussion we have with a patient: We talk about the potential benefits and weigh them against the risks, and together with the patient, we decide whether to move on to that option. So…
If You’Re Not Well Enough to Receive Standard Treatment…
- At Roswell Park, we almost never run out of treatment options, because we have a phase I clinical trials program led by Dr. Igor Puzanov that offers investigational drugsfor patients who are not eligible for any standard treatments. However, clinical trials have fairly strict eligibility requirements, and a patient who is not well enough to undergo standard treatment may not be w…
Hard Discussions
- In addition to seeing patients, I also train medical fellows — doctors who have completed their training in internal medicine but are furthering their training in the subspecialty area of cancer medicine (hematology/oncology). I spend quite a bit of time teaching them how to communicate bad news. Of course, the fastest and easiest thing for a doctor to do is go into the room and offe…
Patient, Physician & Family
- So, in a nutshell, when a cancer treatment stops working, many variables will determine what happens next. Discussions about which road to take can be very different depending on the type of cancer involved, the number of treatment options available, how well the patient is doing and how well the physician communicates. It is important that the pat...