Treatment FAQ

what does treatment of hemophilia often involve

by Prof. Hildegard Torphy Jr. Published 2 years ago Updated 2 years ago
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The best way to treat hemophilia is to replace the missing blood clotting factor so that the blood can clot properly. This is typically done by injecting treatment products, called clotting factor concentrates, into a person's vein.

Medication

Treatments for hemophilia include: Receiving clotting factors replacement therapy Medication Treatment for joint bleeding and other problems associated …

Therapy

Treatment by factor Rest, Ice, Compression, and Elevation (RICE) No – not the stuff you eat. RICE is another treatment option for people with hemophilia. It is often used in conjunction with factor replacement therapy.

Self-care

Sep 27, 2021 · Treatment for Hemophilia B includes transfusions that increase clotting factors in the blood. There are medications that can help patients control their bleeding, but they are only used for people with fewer symptoms of the disease. Surgery can be done to replace damaged joints caused by chronic bleeding.

Nutrition

Mar 22, 2012 · A: Treatment of hemophilia involves replacement of factor VIII chronically, with additional doses administered during phases of acute bleeding.

How do you cure hemophilia?

Mar 10, 2016 · Hemophilia treatment involves the use of injections to replace the missing clotting factor. There are two main approaches: In on-demand treatment, the missing clotting factor is injected only when needed, for instance to stop active bleeding, or before a medical procedure such as surgery or the pulling of teeth, in order to limit blood loss.

Can you cure hemophilia?

Is there any cure for hemophilia?

How to cure hemophilia?

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How to prevent hemophilia?

Lifestyle and home remedies. To avoid excessive bleeding and protect your joints: Exercise regularly. Activities such as swimming, bicycle riding and walking can build up muscles while protecting joints. Contact sports — such as football, hockey or wrestling — are not safe for people with hemophilia.

How to help a child with hemophilia?

To help you and your child cope with hemophilia: Get a medical alert bracelet. This bracelet lets medical personnel know that you or your child has hemophilia, and the type of clotting factor that's best in case of an emergency. Talk with a counselor.

What is the best treatment for internal bleeding?

Fibrin sealants. These medications can be applied directly to wound sites to promote clotting and healing. Fibrin sealants are especially useful in dental therapy. Physical therapy. It can ease signs and symptoms if internal bleeding has damaged your joints.

How to stop bleeding in mouth?

Using pressure and a bandage will generally take care of the bleeding. For small areas of bleeding beneath the skin, use an ice pack. Ice pops can be used to slow down minor bleeding in the mouth. Vaccinations. Although blood products are screened, it's still possible for people who rely on them to contract diseases.

When is hemophilia diagnosed?

Depending on the severity of the deficiency, hemophilia symptoms can first arise at various ages. Severe cases of hemophilia usually are diagnosed within the first year of life.

What is the best medicine to stop bleeding?

Avoid certain pain medications. Drugs that can aggravate bleeding include aspirin and ibuprofen (Advil, Motrin IB, others). Instead, use acetaminophen (Tylenol, others), which is a safer alternative for mild pain relief. Avoid blood-thinning medications.

How to prevent tooth extractions?

Practice good dental hygiene. The goal is to prevent tooth extraction, which can lead to excessive bleeding. Protect your child from injuries that could cause bleeding. Kneepads, elbow pads, helmets and safety belts all may help prevent injuries from falls and other accidents.

What is the severity of hemophilia?

The severity of hemophilia that a person has is determined by the amount of factor in the blood. The lower the amount of the factor, the more likely it is that bleeding will occur which can lead to serious health problems. In rare cases, a person can develop ...

What are the different types of hemophilia?

There are several different types of hemophilia. The following two are the most common: 1 Hemophilia A (Classic Hemophilia)#N#This type is caused by a lack or decrease of clotting factor VIII. 2 Hemophilia B (Christmas Disease)#N#This type is caused by a lack or decrease of clotting factor IX.

How does hemophilia occur?

Hemophilia is caused by a mutation or change, in one of the genes, that provides instructions for making the clotting factor proteins needed to form a blood clot. This change or mutation can prevent the clotting protein from working properly or to be missing altogether. These genes are located on the X chromosome. Males have one X and one Y chromosome (XY) and females have two X chromosomes (XX). Males inherit the X chromosome from their mothers and the Y chromosome from their fathers. Females inherit one X chromosome from each parent.

What causes swelling and pain in the joints?

Bleeding into the joints. This can cause swelling and pain or tightness in the joints; it often affects the knees, elbows, and ankles. Bleeding into the skin (which is bruising) or muscle and soft tissue causing a build-up of blood in the area (called a hematoma).

How many chromosomes do males have?

Males have one X and one Y chromosome (XY) and females have two X chromosomes (XX). Males inherit the X chromosome from their mothers and the Y chromosome from their fathers. Females inherit one X chromosome from each parent. The X chromosome contains many genes that are not present on the Y chromosome.

Can a male have hemophilia?

Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene. Females can also have hemophilia, but this is much rarer. In such cases both X chromosomes are affected or one is affected and the other is missing or inactive.

What is an HTC?

Often the best choice for care is to visit a comprehensive Hemophilia Treatment Center (HTC). An HTC not only provides care to address all issues related to the disorder, but also provides health education that helps people with hemophilia stay healthy. Learn more about treatment.

What are the complications of hemophilia?

Complications from treatment for hemophilia include: 1 Acquiring a blood-borne disease 2 Changes to the immune system that make the treatment less effective

What is factor VIII used for?

Factor VIII replacement is used to treat hemophilia A and Factor IX is used in the treatment of hemophilia B. The clotting factor is given intravenously (through a needle in your vein) to stop or prevent bleeding. Factor preparations come from two sources: Donated blood plasma. Synthetic (DNA-derived)

Why is monitoring physical activity important?

Monitoring physical activity may be necessary to prevent injury and internal bleeding. Your doctor will discuss the types of physical activities that are appropriate and what kinds of activities may be too dangerous. Your doctor's advice depends on the type and severity of hemophilia. Possible Complications from Hemophilia Treatment.

What is fibrin clot?

The fibrin clot is the end-product of many different "clotting factors" reacting in the blood. Hemophilia is an inherited condition in which one of these clotting factors (mainly factor VIII or IX) is absent from the blood, so that it does not clot normally.

How to give DDAVP?

DDAVP can be given intravenously, through an injection, or in the form of nasal spray. Antifibrinolytic medicines such as tranexamic acid and aminocaproic acid are oral medicines that are sometimes used with replacement therapy in certain situations to help keep blood clots from breaking down.

Why is it important to donate blood?

Still, if you have hemophilia it is important for you to receive immunizations for hepatitis A and B to help prevent becoming infected with these viruses.

What is emicizumab KXWH?

Emicizumab -kxwh (HEMLIBRA) is a medicine that can help prevent or reduce the frequency of bleeding episodes in adults and children with hemophilia A. It works by bridging the gap in the clotting factors left by the missing factor VIII. This medication is given as a weekly, under-the-skin (subcutaneous) injection.

Rest, Ice, Compression, and Elevation (RICE)

No – not the stuff you eat. RICE is another treatment option for people with hemophilia. It is often used in conjunction with factor replacement therapy. This treatment can be used when experiencing a bleed away from home until factor is accessible (although it is advised to have factor on-hand whenever possible).

Ports and Venous Access

Factor must be infused into veins. Infants have a high percentage of body fat, which may make finding a vein difficult. For children or adults who require frequent infusions, or those with difficulty accessing a vein, your hematologist may recommend a central venous access device (also known as a port) that is implanted under the skin.

Treatment logs

It is important that you always maintain infusion/treatment logs. They are much more accurate than trying to recall bleed information from memory. They will also serve as a record of infusions and bleeds in the event your factor therapy needs to be modified by your hematologist.

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Diagnosis

Treatment

Clinical Trials

Lifestyle and Home Remedies

Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves injections of the insufficient clotting factors or plasma.
Medication

Antifibrinolytics: Used to prevent clots from breaking down.

Aminocaproic acid . Tranexamic acid


Fibrin sealant: Used to promote clotting.

Aprotinin


Hormone therapy: Carried out by slowly injecting the hormone into a vein to stimulate release of more clotting factors for mild hemophilia A.

Desmopressin

Therapy

Blood transfusion:Transfusion of clotting factor by infusing recombinant clotting factor. Transfusion of plasma are given to patient to stop bleeding.

Physical therapy:Can relieve symptoms, if the joints are damaged due to internal bleeding.

Self-care

Always talk to your provider before starting anything.

Exercise regularly, avoid certain pain medications and blood thinning medications. Practice dental hygiene.

Nutrition

Foods to eat:

  • Vitamin and mineral containing foods such as fruits and vegetables
  • Calcium containing foods such as iceberg lettuce, oranges and almonds
  • Protein containing foods such as dried beans nut and seeds

Foods to avoid:

  • Avoid supplements that might adversely affect bleeding and clotting times such as: ginseng, gingko biloba, bromelain, flaxseed, garlic, ginger, bilberry fruit

Specialist to consult

Hematologist
Specializes in the study of the blood and blood disorders.

Coping and Support

  • Severe cases of hemophilia usually are diagnosed within the first year of life. Mild forms might not be apparent until adulthood. Some people learn they have hemophilia after they bleed excessively during a surgical procedure. Clotting-factor tests can reveal a clotting-factor deficiency and determine how severe the hemophilia is. For people with a family history of hem
See more on mayoclinic.org

Preparing For Your Appointment

  • The main treatment for severe hemophilia involves replacing the clotting factor you need through a tube in a vein. This replacement therapy can be given to treat a bleeding episode in progress. It can also be given on a regular schedule at home to help prevent bleeding episodes. Some people receive continuous replacement therapy. Replacement clotting factor can be made from donate…
See more on mayoclinic.org

Causes

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Types

  • To avoid excessive bleeding and protect your joints: 1. Exercise regularly.Activities such as swimming, bicycle riding and walking can build muscles while protecting joints. Contact sports — such as football, hockey or wrestling — are not safe for people with hemophilia. 2. Avoid certain pain medications.Drugs that can make bleeding worse include aspirin and ibuprofen (Advil, Motr…
See more on mayoclinic.org

Signs and Symptoms

  • To help you and your child cope with hemophilia: 1. Get a medical alert bracelet.This lets medical personnel know that you or your child has hemophilia, and the type of clotting factor that's best in case of an emergency. 2. Talk with a counselor.Striking the right balance between keeping your child safe and encouraging as much activity as possible can be tricky. A social worker or therapi…
See more on mayoclinic.org

Who Is Affected

  • If you or your child has signs or symptoms of hemophilia, you might be referred to a doctor who specializes in blood disorders (hematologist).
See more on mayoclinic.org

Diagnosis

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Hemophilia is caused by a mutationor change, in one of the genes, that provides instructions for making the clotting factor proteins needed to form a blood clot. This change or mutation can prevent the clotting protein from working properly or to be missing altogether. These genes are located on the X chromosome. Males …
See more on cdc.gov

Treatment

  • There are several different types of hemophilia. The following two are the most common: 1. Hemophilia A (Classic Hemophilia) This type is caused by a lack or decrease of clotting factor VIII. 2. Hemophilia B (Christmas Disease) This type is caused by a lack or decrease of clotting factor IX.
See more on cdc.gov

Inhibitors

  • Common signs of hemophilia include: 1. Bleeding into the joints. This can cause swelling and pain or tightness in the joints; it often affects the knees, elbows, and ankles. 2. Bleeding into the skin (which is bruising) or muscle and soft tissue causing a build-up of blood in the area (called a hematoma). 3. Bleeding of the mouth and gums, and bleeding that is hard to stop after losing a t…
See more on cdc.gov

Home Remedies and Lifestyle

  • Hemophilia occurs in about 1 of every 5,000 male births. Based on recent study that used data collected on patients receiving care in federally funded hemophilia treatment centers during the period 2012-2018, about 20,000 as many as 33,000 males in the United States are living with the disorder. Hemophilia A is about four times as common as hemophilia B, and about half of those …
See more on cdc.gov

Over-The-Counter (OTC) Therapies

  • Many people who have or have had family members with hemophilia will ask that their baby boys get tested soon after birth. About one-third of babies who are diagnosed with hemophilia have a new mutation not present in other family members. In these cases, a doctor might check for hemophilia if a newborn is showing certain signs of hemophilia. To make a diagnosis, doctors w…
See more on cdc.gov

Prescriptions

  • The best way to treat hemophilia is to replace the missing blood clotting factor so that the blood can clot properly. This is done by infusing (administering through a vein) commercially prepared factor concentrates. People with hemophilia can learn how to perform these infusions themselves so that they can stop bleeding episodes and, by performing the infusions on a regular basis (call…
See more on cdc.gov

Surgeries and Specialist-Driven Procedures

  • About 15-20 percent of people with hemophilia develop an antibody (called an inhibitor) that stops the clotting factors from being able to clot the blood and stop bleeding. Treatment of bleeding episodes becomes extremely difficult, and the cost of care for a person with an inhibitor can skyrocket because more clotting factor or a different type of clotting factor is needed. People wi…
See more on cdc.gov

Complementary and Alternative Medicine

  • If you have hemophilia A, it’s important that you try to avoid injuries. This can mean avoiding contact sports and other known injury risks. If you get a cut, you might be able to slow down the bleeding by holding pressure over it or by putting ice on it. Don’t place ice directly on your skin—make sure the ice is wrapped to ensure that your skin doesn’t get too cold. It’s also import…
See more on verywellhealth.com

Summary

  • Sometimes hemophilia A can cause joint pain. Generally, Tylenol (acetaminophen) is recommended to help manage the pain.1 There are no OTC therapies that can help treat hemophilia A, but there are some medications that you should avoid: 1. Aspirin is commonly used for pain relief, and it is sometimes recommended for prevention of heart attacks and strokes for …
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A Word from Verywell

  • Hemophilia A can be treated, but there is no cure. The treatments are used long-term. Replacement of factor VIII is the main treatment for hemophilia A, and this treatment is often referred to as clotting factor. Other treatments can prevent bleeding through biological actions that do not specifically replace factor VIII. Treatments include: 1. Clotting factor products: Thes…
See more on verywellhealth.com

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