
Staging is the term oncologists use to define where cancer is located and how much it has spread. Once the stage of cancer is determined, your physician can recommend a particular course of treatment. Most cancer teams use the system developed by the American Joint Committee on Cancer
American Joint Committee on Cancer
The American Joint Committee on Cancer is an organization best known for defining and popularizing cancer staging standards, officially the AJCC staging system. The American Joint Committee on Cancer was established in 1959 to formulate and publish systems of classification of cancer, including staging and end results reporting, which will be acceptable to and used by the medical profession for s…
TNM staging system
The TNM Classification of Malignant Tumours (TNM) is a cancer staging notation system that gives codes to describe the stage of a person's cancer, when this originates with a solid tumor.
What is cancer staging and how does it work?
Staging is the process of finding out how much cancer is in a person’s body and where it’s located. It’s how the doctor determines the stage of a person’s cancer.
How does cancer staging Help the patient?
Stage refers to the extent of your cancer, such as how large the tumor is, and if it has spread. Knowing the stage of your cancer helps your doctor: Understand how serious your cancer is …
What determines the stage of a cancer?
The stage of a cancer is one of the most important things to know when deciding on how to treat the cancer. Each cancer, by organ, has its own staging system. In most cases, the stages are …

What does cancer staging mean?
Is staging and grading of cancer the same?
What are the 4 main stages of cancer and how are they determined?
How is cancer staging determined?
How fast do cancer stages progress?
Is Stage 4 cancer always terminal?
What is the highest stage of cancer?
Is Stage 4 cancer a death sentence?
At what stage of cancer is chemotherapy used?
What are the 3 stages of cancer development?
Can a biopsy tell stage of cancer?
How do you know if cancer has spread to lymph nodes?
What is the staging system used for cancer?
This staging system is more often used by cancer registries than by doctors.
What is the TNM staging system?
Some, such as the TNM staging system, are used for many types of cancer. Others are specific to a particular type of cancer. Most staging systems include information about: Where the tumor is located in the body. The cell type (such as, adenocarcinoma or squamous cell carcinoma) The size of the tumor. Whether the cancer has spread ...
What is CIS in cancer?
Also called carcinoma in situ, or CIS. CIS is not cancer, but it may become cancer. Stage I, Stage II, and Stage III. Cancer is present. The higher the number, the larger the cancer tumor and the more it has spread into nearby tissues. Stage IV. The cancer has spread to distant parts of the body.
What is stage IV cancer?
Stage IV. The cancer has spread to distant parts of the body. Another staging system that is used for all types of cancer groups the cancer into one of five main categories. This staging system is more often used by cancer registries than by doctors.
What is cancer in situ?
In situ —Abnormal cells are present but have not spread to nearby tissue. Localized —Cancer is limited to the place where it started, with no sign that it has spread. Regional —Cancer has spread to nearby lymph nodes, tissues, or organs. Distant —Cancer has spread to distant parts of the body.
What is localized cancer?
Localized —Cancer is limited to the place where it started, with no sign that it has spread. Regional —Cancer has spread to nearby lymph nodes, tissues, or organs. Distant —Cancer has spread to distant parts of the body. Unknown —There is not enough information to figure out the stage.
What is regional cancer?
Regional —Cancer has spread to nearby lymph nodes, tissues, or organs. Distant —Cancer has spread to distant parts of the body. Unknown —There is not enough information to figure out the stage. To learn more about staging for your type of cancer, see the PDQ ® cancer treatment summaries for adult and childhood cancers.
What is the difference between stage 1 and stage 2 cancer?
Most kinds of cancer do not use this stage. Stage I. Cancer is only in the cells where it first started and the area is small. This is considered early stage and most curable. Stage II. Cancer is in the organ where it first started. It may be a bit larger than stage I and/or may have spread to nearby lymph nodes.
What is the first stage of cancer?
Stage I. Cancer is only in the cells where it first started and the area is small. This is considered early stage and most curable. Stage II.
What happens after cancer diagnosis?
After cancer is diagnosed, healthcare providers will begin to determine the grade and stage of the cancer. This helps them to plan the best treatment and look at overall outcomes and goals.
What does the grade of cancer mean?
What does the grade of a cancer mean? The grade of a cancer describes what the cancer cells look like using a microscope. Most cancers are graded by how they compare with normal cells. Low grade or grade I tumors are well-differentiated. This means that the tumor cells are organized and look more like normal tissue.
How are cancers graded?
Most cancers are graded by how they compare with normal cells. Low grade or grade I tumors are well-differentiated. This means that the tumor cells are organized and look more like normal tissue. High grade or grade III tumor cells are poorly differentiated. This means that the tumor cells don't look like normal cells.
What is a grade II tumor?
They're disorganized under the microscope and tend to grow and spread faster than grade I tumors. Cancer cells that don't look well-differentiated or poorly differentiated are called moderately differentiated, or grade II. In general, cancer cells are graded using the scale below.
Is carcinoma in situ pre-malignant?
Carcinoma in situ is considered pre-malignant or pre-cancer. Abnormal cells are found only in the first layer of cells in the place where the changes first started. The cells do not invade the deeper tissues. These cells may become cancer over time, so it's good to find and treat them before that happens.
What is cancer staging?
Cancer staging can be clinical or pathological: 1 Clinical Staging: Based on test results received before surgery, such as physical exams, lab tests, and imaging scans 2 Pathological Staging: Based on what the doctor finds during surgery and provides the most accurate information about a patient’s prognosis
Why is staging important?
According to the National Cancer Institute, staging is an important tool that provides doctors with information about where the cancer is located, how large the tumor is, and whether it has spread to other parts of the body.
How many stages of cancer are there?
After conducting an array of tests, doctors often assign cancer to one of five stages: Stage 0, Stage 1, Stage 2 , Stage 3 , or Stage 4. Sometimes, these stages can be further divided using letters, such as Stage 2A or Stage 3B.
What does the letter T mean in cancer?
The National Cancer Institute explains how each letter of the system helps health care providers evaluate the extent of cancer in the body: T: Refers to the size and location of the primary tumor. N: Refers to the number of nearby lymph nodes that have cancer.
What is clinical staging?
Clinical staging is based on the results of tests done before surgery, such as physical examinations and imaging scans. Pathological staging is based on what is found during surgery. Clinical stage is often indicated with a lowercase “c” before the TNM classification.
How to tell if a cancer is staged?
Staging helps describe where a cancer is located, if or where it has spread, and whether it is affecting other parts of the body. Doctors often use diagnostic tests to determine a cancer’s stage. Staging may not be complete until all of these tests are finished. Knowing the stage helps the doctor: 1 Plan treatment, including the type of surgery and/or whether chemotherapy or radiation therapy are needed 2 Predict the chance that the cancer will come back after the original treatment 3 Predict the chance of recovery 4 Talk about the diagnosis in a clear, common language with the entire health care team 5 Determine how well the treatment worked 6 Compare how well new treatments work among large groups of people with the same diagnosis
How to predict cancer?
Predict the chance that the cancer will come back after the original treatment. Predict the chance of recovery. Talk about the diagnosis in a clear, common language with the entire health care team. Determine how well the treatment worked.
What does the letter M mean in cancer?
The letter "M" indicates whether the cancer has spread to other parts of the body, called distant metastasis. If the cancer has not spread, it is labeled M0. If the cancer has spread, it is considered M1.
How many stages of cancer are there?
Doctors combine the T, N, M results and other factors specific to the cancer to determine the stage of cancer for each person. Most types of cancer have four stages: stages I (1) to IV (4). Some cancers also have a stage 0 (zero).
What is the difference between stage 0 and stage 1 cancer?
Stage 0 cancers are still located in the place they started and have not spread to nearby tissues. This stage of cancer is often highly curable, usually by removing the entire tumor with surgery. Stage I. This stage is usually a small cancer or tumor that has not grown deeply into nearby tissues.
Does cancer change over time?
The stage of a cancer does not change over time. If the cancer comes back or spreads to another part of the body, the more recent information about the size and spread of the cancer is added to the original stage.
What is cancer staging?
Cancer staging is a way to describe how much cancer is in your body and where it is located in your body. Staging helps determine where the original tumor is, how big it is, whether it has spread, and where it has spread. Cancer staging can help your health care provider:
How does staging help cancer?
Staging helps determine where the original tumor is, how big it is, whether it has spread, and where it has spread. Cancer staging can help your health care provider: Determine your prognosis (chance of recovery or likelihood the cancer will come back) Plan your treatment.
What is expand section?
Expand Section. Cancer is the uncontrolled growth of abnormal cells in the body. These cells often form a tumor. This tumor can grow into the surrounding tissues and organs. As the cancer progresses, cancer cells from the tumor can break away and spread to other parts of the body through the bloodstream or lymph system.
What is the uncontrolled growth of abnormal cells in the body?
Cancer is the uncontrolled growth of abnormal cells in the body. These cells often form a tumor. This tumor can grow into the surrounding tissues and organs. As the cancer progresses, cancer cells from the tumor can break away and spread to other parts of the body through the bloodstream or lymph system. When cancer spreads, tumors can form in ...
How does cancer spread?
As the cancer progresses, cancer cells from the tumor can break away and spread to other parts of the body through the bloodstream or lymph system. When cancer spreads, tumors can form in other organs and parts of the body. The spread of cancer is called metastasis. Cancer staging is used to help describe the progression of cancer.
What is the term for the spread of cancer?
The spread of cancer is called metastasis. Cancer staging is used to help describe the progression of cancer. It is often defined by: Location of the primary (original) tumor and type of cancer cells. Size of the primary tumor. Whether the cancer has spread to lymph nodes. Number of tumors from the cancer that has spread.
What tests can be done to determine if you have cancer?
Imaging tests, such as x-rays, CT scans, PET scans, or MRIs. Lab tests. Biopsy. You also may have surgery to remove the cancer and lymph nodes or to explore the cancer in your body and take a tissue sample. These samples are tested and can provide more detailed information about the cancer stage.
What does the stage of cancer mean?
What do cancer stages and grades mean? The stage of a cancer describes the size of a tumour and how far it has spread from where it originated. The grade describes the appearance of the cancerous cells. If you're diagnosed with cancer, you may have more tests to help determine how far it has progressed. Staging and grading the cancer will allow the ...
What is the difference between stage 1 and stage 2 cancer?
stage I – the cancer is small and hasn't spread anywhere else. stage II – the cancer has grown, but hasn't spread. stage III – the cancer is larger and may have spread to the surrounding tissues and/or the lymph nodes (part of the lymphatic system )
What is stage 3 cancer?
stage III – the cancer is larger and may have spread to the surrounding tissues and/or the lymph nodes (part of the lymphatic system ) stage IV – the cancer has spread from where it started to at least one other body organ; also known as "secondary" or "metastatic" cancer.
What does a lower grade mean for cancer?
In general, a lower grade indicates a slower-growing cancer and a higher grade indicates a faster-growing one. The grading system that's usually used is as follows: grade I – cancer cells that resemble normal cells and aren't growing rapidly.
The impact of DNA changes on breast cancer
In the past, most breast cancer patients with lymph node involvement were automatically classified as stage II or higher, and were often given chemotherapy.
How will these changes affect you?
The impact of these staging changes will be far greater for patients with cancers diagnosed on or after Jan. 1, 2018.
