What is refractory cancer and how is it treated?
refractory. [ re-frak´tah-re] 1. not readily yielding to treatment. 2. not responding to a stimulus. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
What does refractory mean in medical terms?
Jan 31, 2018 · Published: January 31, 2018. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment.
What does treatment refractory mean?
Definition of refractory. (Entry 1 of 2) 1 : resisting control or authority : stubborn, unmanageable. 2 a : resistant to treatment or cure a refractory lesion. b : unresponsive to stimulus. c : immune, insusceptible after recovery they were refractory to infection.
What does it mean to be refractory?
Mar 29, 2021 · Refractory: Not yielding, or not yielding readily, to treatment. CONTINUE SCROLLING OR CLICK HERE QUESTION What causes tooth decay? See Answer Health Solutions From Our Sponsors Penis Curved When Erect Could I have CAD? Treat Bent Fingers Treat HR+, HER2- MBC Tired of Dandruff? Life with Cancer
What does refractory mean?
1 : resisting control or authority : stubborn, unmanageable. 2a : resistant to treatment or cure a refractory lesion. b : unresponsive to stimulus. c : immune, insusceptible after recovery they were refractory to infection.
What does it mean when cancer is refractory?
Listen to pronunciation. (reh-FRAK-tor-ee KAN-ser) Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment or it may become resistant during treatment.
What is chemo refractory?
Chemorefractory: This means cancer does not shrink or go away when the chemo drugs are given. Sometimes, cancer that is chemorefractory is called a "failure of cancer chemotherapy," or a "resistance to chemotherapy."8.Mar 13, 2022
What is the difference between relapse and refractory?
What are relapsed and refractory diseases? Relapsed disease means a cancer has come back. Refractory disease means a cancer has stopped responding to treatment.Dec 1, 2020
What is the life expectancy of someone with multiple myeloma?
Multiple myeloma is an uncommon cancer of the blood. The median length of survival after diagnosis with multiple myeloma is 62 months for Stage I, 44 months for Stage II, and 29 months for Stage III. Life expectancy depends on many factors, including the person's age, health, kidney function, and more.Jun 11, 2021
How do you know cancer has metastasized?
Some common signs of metastatic cancer include:pain and fractures, when cancer has spread to the bone.headache, seizures, or dizziness, when cancer has spread to the brain.shortness of breath, when cancer has spread to the lung.jaundice or swelling in the belly, when cancer has spread to the liver.Nov 10, 2020
What is refractory multiple myeloma?
What Is Refractory Multiple Myeloma? Multiple myeloma is a cancer that affects a type of white blood cell called a plasma cell, which helps your immune system fight infections. Refractory means your cancer doesn't improve with treatment, or it stops responding to treatment.Apr 22, 2021
What is Advanced Refractory?
Advanced Refractory Technologies is a provider and manufacturer of refractory products for industry. Elgin, Illinois, United States. www.advancedrefractory.com.
What is refractory melanoma?
Definition. Melanoma that does not respond to treatment. [ from NCI]
How quickly can lymphoma relapse?
Most relapses of Hodgkin lymphoma or high-grade non-Hodgkin lymphoma happen within the first 2 years after treatment. As time goes on, relapse generally becomes less likely.
How I treat refractory acute lymphoblastic leukemia?
Chemotherapy. Chemotherapy is the primary treatment for relapsed and refractory ALL. When it is given for relapsed and refractory ALL, it is called reinduction chemotherapy. If ALL relapses after a long remission, it may respond to the drugs used in the original treatment.
What do you call it when a disease comes back?
Listen to pronunciation. (REE-laps) The return of a disease or the signs and symptoms of a disease after a period of improvement.
Where does the word "refractory" come from?
Refractory is from the Latin word refractarius. During the 17th century, it was sometimes spelled as refractary, but that spelling, though more in keeping with its Latin parent, had fallen out of use by the century's end. Refractarius, like refractory, is the result of a slight variation in spelling. It stems from the Latin verb refragari, meaning ...
What does "unruly" mean?
unruly, ungovernable, intractable, refractory, recalcitrant, willful, headstrong mean not submissive to government or control. unruly implies lack of discipline or incapacity for discipline and often connotes waywardness or turbulence of behavior. unruly children ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others. ungovernable rage intractable suggests stubborn resistance to guidance or control. intractable opponents of the hazardous-waste dump refractory stresses resistance to attempts to manage or to mold. special schools for refractory children recalcitrant suggests determined resistance to or defiance of authority. acts of sabotage by a recalcitrant populace willful implies an obstinate determination to have one's own way. a willful disregard for the rights of others headstrong suggests self-will impatient of restraint, advice, or suggestion. a headstrong young cavalry officer
Citation
"refractory." Definitions.net. STANDS4 LLC, 2021. Web. 5 Sep. 2021. < https://www.definitions.net/definition/refractory >.
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What is refractory leukemia?
Patients who still have cancer cells in their bone marrow after treatment have refractory leukemia. Relapsed lymphoma is a disease that responded to treatment initially, but then returned. Refractory disease means the cancer hasn’t responded to the initial treatment (it could be getting worse or staying the same).
What is relapsed disease?
What are relapsed and refractory diseases? Relapsed disease means a cancer has come back. Refractory disease means a cancer has stopped responding to treatment. “Most hematologic cancers, like leukemia, lymphoma, and multiple myeloma, are initially very sensitive to treatment.
What are the different types of blood cancer?
Relapsed and refractory disease can be different depending on the type of blood cancer: 1 With leukemia, people who have been in remission can have a return of cancer cells and a decrease in normal blood cells. This is a relapse. Patients who still have cancer cells in their bone marrow after treatment have refractory leukemia. 2 Relapsed lymphoma is a disease that responded to treatment initially, but then returned. Refractory disease means the cancer hasn’t responded to the initial treatment (it could be getting worse or staying the same). 3 With multiple myeloma, almost all patients will experience a relapse or will see the disease become refractory.
Can cancer go into remission?
Patients very commonly go into remission when we treat them,” Styler said. “But ultimately, there may be some cancer cells that are just inherently resistant to those treatments, and over time, they start to multiply and the disease comes back again. At that point, it’s actually quite resistant to standard therapy.”.
What is refractory AML?
Patients who have not achieved complete remission after two cycles of induction chemotherapy are usually diagnosed as having "refractory AML.". Relapsed AML: Some patients reach remission and then have a return of leukemia cells in the marrow and a decrease in normal blood cells. This is called “relapsed leukemia.”.
When to use stem cell transplant?
Stem cell transplantation may be used when remission is achieved , which may result in a more durable remission. For relapsed AML, re-treatment with the same induction regimen that produced the patient's first remission may be used.