First-line treatment or therapy simply refers to the initial, or first treatment recommended for a disease or illness. This may also be referred to as primary treatment, initial treatment, or induction therapy. With many conditions, including cancer, there are many possible treatments that could be effective.
What is the definition of first line therapy?
first-line treatment The initial, preferred, or best treatment for a disease. It is often the therapy that combines the best efficacy with the best safety profile and/or the lowest cost. Synonym: first-line therapy Medical Dictionary, © 2009 Farlex and Partners Want to thank TFD for its existence?
What is first line of therapy?
first-line treatment (redirected from First-line therapy) first-line treatment The initial, preferred, or best treatment for a disease. It is often the therapy that combines the best efficacy with the best safety profile and/or the lowest cost. Synonym: first-line therapy Medical Dictionary, © …
What is the best first line of treatment for hypertension?
First line therapy is the treatment regimen or regimens that are generally accepted by the medical establishment for initial treatment of a given type and stage of cancer. It is also called primary treatment or therapy. The intent of first-line therapy is to cure the cancer if possible.
What is first-line chemotherapy?
first-line adjective Save Word \ ˈfərst-ˈlīn \ Definition of first-line : being the preferred, standard, or first choice first-line treatment of tuberculosis — compare second-line Synonyms for first-line …
What is the difference between first-line and second-line treatment?
Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren't tolerated.Jun 9, 2020
What does line of treatment mean?
“Lines of therapy” is the term used to describe the order in which different therapies are given to people as their disease progresses.May 5, 2021
What is 2nd line therapy?
Treatment that is given when initial treatment (first-line therapy) doesn't work, or stops working.
What does third line treatment mean?
Treatment that is given when both initial treatment (first-line therapy) and subsequent treatment (second-line therapy) don't work, or stop working.
What is a first-line antibiotic?
Amoxicillin or amoxicillin/clavulanate is the recommended first-line therapy. Macrolides such as azithromycin are not recommended due to high levels of Streptococcus pneumoniae antibiotic resistance (~40%).
What is first-line and second-line chemotherapy?
How well your treatment works often varies. Your first-line treatment may not work, may start but then stop working, or may cause serious side effects. Your doctor may then suggest a second-line treatment, also called second-line therapy. It is a different treatment that is likely to be effective.
What are the signs that chemo is working?
Complete response - all of the cancer or tumor disappears; there is no evidence of disease. A tumor marker (if applicable) may fall within the normal range. Partial response - the cancer has shrunk by a percentage but disease remains. A tumor marker (if applicable) may have fallen but evidence of disease remains.
What are the signs that chemo is not working?
Here are some signs that chemotherapy may not be working as well as expected: tumors aren't shrinking. new tumors keep forming. cancer is spreading to new areas.Jul 31, 2019
What is a line of chemo?
A PICC line (peripherally inserted central catheter line) is used to give someone chemotherapy treatment or other medicines. A PICC line is a long, thin, hollow, flexible tube called a catheter. It is put into one of the large veins of the arm, above the bend of the elbow.
Is chemo worse the second time around?
Don't plan your chemo response until you've gone through your first infusion. The effects of chemo are cumulative. They get worse with each cycle.
What happens after 2nd chemo treatment?
You may experience nausea (feeling like you might throw up) and vomiting (throwing up) after your last chemotherapy treatment. It should go away in 2 to 3 weeks. Your appetite may continue to be affected due to taste changes you may have experienced during your treatment.Feb 7, 2022
How long does it take for a tumor to shrink after radiation?
For tumors that divide slowly, the mass may shrink over a long, extended period after radiation stops. The median time for a prostate cancer to shrink is about 18 months (some quicker, some slower).
What is the ADU S100?
Aduro Biotech announced that the first patient has been dosed in a Phase 2 clinical trial of ADU-S100, a novel STING pathway activator, in combination with KEYTRUDA, an approved anti-PD-1 antibody, as a first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma.The Phase 2, open-label, multicenter trial, which is part of an ongoing research and development collaboration with Novartis, is designed to evaluate the efficacy and safety of ADU-S100 administered intratumorally in combination with pembrolizumab in the first-line setting.
Is Tagrisso approved in China?
AstraZeneca announces approval for Tagrisso in China as first-line treatment for EGFR-mutated non-small cell lung cancer. Global Banking News-September 5, 2019-AstraZeneca announces approval for Tagrisso in China as first-line treatment for EGFR-mutated non-small cell lung cancer. AstraZeneca announces approval for Tagrisso in China as first-line ...
What is first line therapy?
First line therapy is the treatment regimen or regimens that are generally accepted by the medical establishment for initial treatment of a given type and stage of cancer. It is also called primary treatment or therapy. The intent of first-line therapy is to cure the cancer if possible. Also called induction therapy, ...
What is the first line of treatment for cancer?
First-line therapies for cancers are usually one or a combination of: radiation, surgery, and chemotherapy. There are different types of these treatment modalities. Variations and tweaks to the therapy regimens may be employed as the doctor takes into account the patient’s age, general health, other diseases, and stage of cancer.
What is induction therapy?
Also called induction therapy, this primary therapy is the first assault of chemotherapy drugs on the malignancy. The US government’s Agency for Healthcare Research and Quality operates a clearinghouse of evidence-based clinical practice guidelines as do other organizations – both governmental and non-governmental around the world.
What is the second line of medicine?
What classifies a medicine as the second line? 1 It’s not proven. It may work for some, but not all people with asthma. A good example here is Singular. It helps some asthmatics, but not all. Biologics like Xolair may also fit into this category. It’s a relatively new line of treatment. So, future studies may reveal it only helps some asthmatics. 2 There’s a greater risk for side effects. Systemic corticosteroids fit nicely into this category. They work great for ending asthma attacks and controlling asthma. But, the risk for side effects is too great. So, they sit as second-line treatments ready to be prescribed if and when needed. 3 It’s not cost effective. Xolair costs thousands of dollars. Because it costs so much, it’s reserved as a second-line option. At the present time, all biologics fit into this category. 4 It’s not easy to administer. Xolair needs to be injected into a vein. So, it’s not easy to give to yourself. 5 Doctors are not as comfortable with it. Xolair is a newer medicine. So, some doctors may be leary of it. This relegates it to second-line status. So, new medicines may fit into this category.
What is the best medicine for asthma?
For asthma, they include systemic corticosteroids like Flovent, Asmanex, and Qvar. They include combination inhalers like Advair, Symbicort, Dulera, and Breo. These medicines are the first choices doctors will prescribe when trying to help you obtain better asthma control. One or a combination of these will work for most asthmatics.
Is it safe to use a nebulizer for asthma?
Doctors are comfortable prescribing it. They recognize that it will benefit you. They are confident it’s safe and effective. Most asthma experts recommend all asthmatics have a rescue inhaler like albuterol handy at all times.
Do corticosteroids work for asthma?
There’s a greater risk for side effects. Systemic corticosteroids fit nicely into this category. They work great for ending asthma attacks and controlling asthma. But, the risk for side effects is too great. So, they sit as second-line treatments ready to be prescribed if and when needed. It’s not cost effective.
Is ICS safe for asthma?
After studying this hard, researchers learned ICS are safe and effective for controlling asthma. This moved ICS out of second-line into the first-line status. Better, stronger, safer medicinal options become available. A good example here is theophylline. It was a first-line asthma medicine during the 1970s and 80s.
Can albuterol cause thrush?
Both medicines may cause tremors, but it’s often considered a good trade-off for being able to breathe. Advair may cause thrush. But, it’s both preventable by rinsing and treatable. It’s cost effective.
Is corticosteroids a first line treatment for COPD?
So, it remains a first-line treatment for COPD. Likewise, because it may help some asthmatics, it remains a second-line option here. Researchers learn more. Back in the 1970s, doctors were leary that inhaled corticosteroids (ICS) may cause the same side effects as systemic corticosteroids.
Understanding First-Line Treatment
Questions to Ask
- When you and your healthcare provider consider a first-line treatment or first-line treatments, think through these questions. 1. Clarify the type and stage and molecular profile of your tumor. Is there any further testing that should be done? (If you've been diagnosed with advanced cancer, ask about the molecular profile of your tumor, and if this hasn't been done, ask why not). 2. What is y…
Alternative and Complementary Treatments
- It's important when talking about treatment to clarify what is meant by "alternative treatments." Most people now use the phrase alternative treatments to refer to complementary treatments that are offered by some cancer centers. In this setting, therapies such as acupuncture, meditation, massage, and yoga are used in an integrative fashion—that is, they are used along with tradition…