Treatment FAQ

what clinical and laboratory values are needed to evaluate therapy for treatment of osteoarthritis?

by Karen Quigley Published 2 years ago Updated 2 years ago

Which lab findings are characteristic of osteoarthritis (OA)?

Osteoarthritis (OA) is the most common joint disease and a leading cause for impaired function and disability with significant treatment costs and socio-economic burden. Despite recent …

Why is early diagnosis of osteoarthritis important?

Most patients with knee and hip osteoarthritis (OA) should be treated in primary care by non-surgical treatments. Building on substantial evidence from randomised trials, exercise therapy …

What is included in a physical exam for arthritis?

Oct 30, 2021 · However, the abnormal and clinically significant laboratory values of aspartate aminotransferase (AST) were observed in 1 (7.7%) subject in 32M and 1 (8.3%) subject in the …

What tests are used to differentiate osteoarthritis from rheumatoid arthritis (RA)?

Mar 21, 2021 · The most recorded functional tests were the Arthritis Hand Function Test (AHFT) (n = 7), the Moberg Pick-Up Test (MPUT) (n = 7), the Jebsen-Taylor Hand Function Test …

What is the treatment for knee and hip osteoarthritis?

Most patients with knee and hip osteoarthritis (OA) should be treated in primary care by non-surgical treatments. Building on substantial evidence from randomised trials, exercise therapy and education, typically delivered by physical therapists, are core first line treatments universally recommended in treatment guidelines for OA alongside weight ...

Is exercise therapy the same as pharmacological pain?

Exercise therapy provides at least as effective pain relief as pharmac ological pain medications, without serious adverse effects; furthermore, the treatment effect from exercise therapy is similar, irrespective of baseline pain intensity and radiographic OA severity.

What are the best diagnostic tools for osteoarthritis?

Two of the best diagnostic tools a doctor has are her ears. Taking a thorough medical history and having a discussion about your symptoms, in addition to examining you physically, are very important to arrive at an osteoarthritis diagnosis.

What is the best way to diagnose osteoarthritis?

Your medical history, physical examination, and imaging studies help diagnose osteoarthritis. During the physical exam, your doctor will check for joint swelling and range of motion. Imaging studies (X-rays) look for joint abnormalities and loss of cartilage.

What does your medical history tell you about your osteoarthritis?

Your medical history tells the doctor about the onset of your osteoarthritis symptoms , past treatments or surgeries, your family history of the disease, and other significant details about your condition.

What is the purpose of a physical exam?

Physical Exam. During the physical examination, your doctor will assess each of your joints for pain, tenderness, and range of motion. Determining the pattern of affected joints has significance and can often distinguish between rheumatoid arthritis and osteoarthritis (for example, one knee or both knees affected).

What doctor can diagnose OA?

If your doctor suspects you have very advanced osteoarthritis or that your joint pain and swelling may be due to something else, they can refer you to a rheumatologist, a doctor who specializes in joint diseases.

How to prepare for a medical exam?

Be prepared in advance. Write down or record the information to bring with you so you won't leave out important clues . While you may think some information should already be in your medical record, it is best to recap them. Past surgeries and injuries, including any recent injuries, are important to discuss during your examination.

Why is the space between the bones narrower on an X-ray?

This is because the cartilage that would normally form a cushion between the bones is disintegrating or has worn away completely. 7

What are the treatment options for osteoarthritis?

All patients with osteoarthritis should receive at least some treatment from the first two categories. Surgical manage- ment should be reserved for those who do

How to reduce weight load in osteoarthritis?

Other nonpharmacologic treatments include bracing and splinting to help sup- port painful or unstable joints. A cane can help reduce the weight load in persons with hip or knee osteoarthritis, but it needs to be properly fitted and used on the side contra- lateral to the affected joint.

How to treat osteoarthritis of the hip and shoulder?

Begin with acetaminophen and continue if still effective, or step up to NSAID Discuss total joint replacement for osteoarthritis of the hip, knee, or shoulder if steps below are unsuccessful Consider hyaluronic acid injection for persistent knee osteoarthritis Consider corticosteroid injection for acute exacerbation of knee osteoarthritis Consider opioid therapy, but monitor carefully for dependence and abuse Add combination glucosamine and chondroitin for moderate to severe knee osteoarthritis; discontinue if no change after three months, but continue if effect is noted Start NSAID therapy, beginning with over-the-counter ibuprofen or naproxen; switch to different NSAID if initial choice is not effective; use generics if possible Encourage regular exercise throughout treatment and encourage weight loss if patient is overweight or obese Consider physical therapy referral for supervised exercise (land- or water-based); consider bracing and splinting Mild osteoarthritis Moderate osteoarthritis Severe osteoarthritis

How long does osteoarthritis pain last?

Osteoarthritis can cause morn- ing stiffness, but it usually lasts for less than 30 minutes, unlike rheumatoid arthritis, which causes stiffness for 45 minutes or more.3Patients may report joint locking or joint instability. These symptoms result in loss of function, with patients limiting their activities of daily living because of pain and stiffness. The joints most commonly affected are the hands, knees, hips, and spine, but almost any joint can be involved. Osteoarthritis is often asymmetric. A patient may have severe, debilitating osteoarthritis of one knee with almost normal function of the opposite leg. Physical examination is important in making the diagnosis. Pain on range of motion and limitation of range of motion are common to all forms of osteoarthritis, but each joint has unique physical examina- tion findings (Table 1). Figure 1 shows a hand with typical changes of osteoarthritis. Because osteoarthritis is primarily a clini- cal diagnosis, physicians can confidently make the diagnosis based on the history and physical examination. Plain radiography can be helpful in confirming the diagnosis and ruling out other conditions.1Advanced imaging techniques, such as computed

What is the degen - erative disorder of the articular cartilage associated with hyper- troph

Osteoarthritis is a common degen - erative disorder of the articular cartilage associated with hyper- trophic changes in the bone.1

What are the best exercises for osteoarthritis?

Swimming, elliptical train - ing, and cycling are exer- cise options for patients with osteoarthritis in weight-bearing joints.

What is the most common symptom of osteoarthritis?

The most common symptom of osteoarthri-tis is joint pain. The pain tends to worsen with activity, especially following a period of rest; this has been called the gelling phe-nomenon. Osteoarthritis can cause morn-ing stiffness, but it usually lasts for less than

What is a WOMAC score?

The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to measure the pain and function before and after the therapy [ 22 ]. The specific primary endpoint was change in WOMAC score from baseline to the 46th day when treatment finished. The WOMAC is a questionnaire composed of 24 questions. It was developed for patients with osteoarthritis of the knee and measures three subscales: pain, stiffness, and joint function. Higher scores indicate more severe symptoms.

Is Miao needle therapy worse than acupuncture?

This study shows that the efficacy of Miao crossbow needle therapy is no worse than that of acupuncture therapy. The WOMAC score was lower after treatment in the CN group on the 46th, 62nd, and 77th day. In addition, the VAS score was lower and the Lysholm knee score and JOA score were higher in CN group. The adverse events of crossbow needle therapy and acupuncture therapy were not significantly different.

Clinical Practice Guidelines

To support evidence-based practice, we provide relevant clinical practice guidelines for APTA members. (These were previously housed at PTNow.)

All CPGs

Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline from the American Physical Therapy Association (CPG+)

1. Introduction

Lameness, and more specifically, joint disease, causes significant loss of use of athletic horses and has a large economic impact on the horse industry. Despite numerous medical treatments, novel treatments are needed.

2. Materials and Methods

This study was a blinded, experimentally controlled randomized block design that used 24 horses in an established model of OA [4]. On day 0 of the study, arthroscopic surgery was performed on both midcarpal joints of all horses, and OA was induced in one of the midcarpal joints.

3. Results

Induction of OA resulted in a significant increase in lameness in the corresponding limbs. Significant improvement in clinical lameness (1.7-fold) was noted at the first evaluation time point post-treatment (14 days) in the ESWT-treated horses compared with both the sham and positive control groups.

4. Discussion

This study used an established model of OA that has been used to test various medical treatments for arthritis, such as intra-articular corticosteroids, intravenous hyaluronan, and intramuscular pentosan polysulfate. Furthermore, the induction of arthritis has been shown to result in clinical lameness and histologic and biochemical alterations.

Intake and Examination

Image
Two of the best diagnostic tools a healthcare provider has are her ears. Taking a thorough medical history and having a discussion about your symptoms, in addition to examining you physically, are very important to arrive at an osteoarthritis diagnosis.
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Labs and Tests

  • Routine laboratory tests are sometimes performed to rule out systemic diseases. In addition, healthcare providers sometimes test inflammatory markers, such as C-reactive protein and sedimentation rate, to determine whether the joint discomfort is the product of a systemic inflammatory condition. When there is joint swelling, synovial fluid analysiscan determine wheth…
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Imaging

  • X-rays are typically used to confirm the diagnosis of osteoarthritis. X-rays can reveal assymetric joint space narrowing, osteophytes at the joint margins, joint space narrowing, and subchondral bone sclerosis. Subchondral bone is the layer of bone that is just below the cartilage. While magnetic resonance imaging (MRI)is a more sensitive imaging m...
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Diagnostic Criteria

  • Your healthcare provider will use all of this information to come to a diagnosis. The American College of Rheumatology has established classification criteria, described below, for primary osteoarthritis of the hand, hips, and knees. Osteoarthritis of the Hand2 1. Handpain, aching, or stiffness 2. Hard tissue enlargement of two or more of 10 selected joints 3. Fewer than three sw…
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Differential Diagnoses

  • Part of this process is differentiating osteoarthritis from other types of arthritis. It is also important to determine whether a patient has primary osteoarthritis or a secondary form of osteoarthritis associated with another disease or condition. Other issues that have symptoms similar to osteoarthritis include: 1. Rheumatoid arthritis 2. Gout 3. Lupus Blood tests can often b…
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A Word from Verywell

  • Osteoarthritis is an extremely common cause of joint pain. It is generally a straightforward diagnosis that your healthcare provider will make in their office without further testing. In some cases, your practitioner will utilize laboratory testing and imaging to rule out other underlying inflammatory conditions, such as rheumatoid arthritis.
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