Treatment FAQ

what class of drugs is used in the acute treatment of migraines

by Anastasia Little Published 3 years ago Updated 2 years ago
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  • Triptans, a class of drugs designed to treat migraines. Medications in this category include Imitrex, Relpax, Amerge, Frova, Axert, Maxalt, and Zomig. ...
  • Butalbital, a sedative, is often combined with acetaminophen, aspirin, caffeine, or codeine to treat migraines. Narcotics like meperidine are also an option.
  • Ergotamine, a decades-old option, which has been used to treat migraines since before the introduction of triptans in 1992.
  • Over-the-counter painkillers such as acetaminophen and nonsteroidal anti-inflammatories like ibuprofen and naproxen can help ease migraines, too.
  • There are also options for preventing or reducing the frequency of migraine attacks, including drugs such as amitriptyline, ergonovine, propranolol, clonidine, methysergide, cyproheptadine, calcium channel antagonists, valproic acid, carbamazepine, and ...

Triptans. As a class of drugs, the triptans, were specifically developed for the acute treatment of migraine.Dec 12, 2017

What is the drug of choice for migraine?

What is the drug of choice for moderate-severe migraines? Triptans. What are the three mechanisms of action for triptans? Vasoconstriction, peptide inhibition, and transmission inhibition. What are the contraindications for triptans? Recent MI, History of Angina Pectoris, History of HTN, HEMIPLEGIC/BASILAR migraine.

What is the best treatment for migraine?

The 10 Best Migraine Relief Products That Aren't Total Bunk

  • Premium EVA Foam Roller. If your migraines leave you with an aching neck, roll out the knots with this foam roller. ...
  • Acupressure Mat and Pillow Set. ...
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How effective is ketorolac for migraines?

Who should and should not take ketorolac

  • Other medication. People who regularly take other NSAIDs, such as ibuprofen, naproxen, or aspirin, may have a higher risk of stroke or heart attack when receiving ketorolac.
  • Family medical history. ...
  • Bleeding or clotting. ...
  • Upcoming surgery. ...
  • Ulcers. ...
  • Kidney or liver disease. ...
  • Pregnant, breastfeeding, or giving birth. ...
  • Allergies. ...
  • Asthma. ...

What is the treatment for acute migraine?

Zosano Pharma Corporation (NASDAQ: ZSAN) announced that an article titled, "Long Term Safety, Tolerability, and Efficacy of Intracutaneous Zolmitriptan (M207) in the Acute Treatment of Migraine" was published in the Journal of Headache and Pain

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What is the best medication for migraines?

Triptans are most effective for moderate to severe migraines and work best when taken at the earliest sign of an impending attack. These drugs not only fend off pain, they also help to alleviate nausea and sensitivity to light and sound, which are common symptoms of migraine attacks. They do this by stimulating receptors for ...

What is the best treatment for migraine headaches?

There are two classes of non-prescription painkillers: acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is triptan used for?

Triptans are a class of prescription medication often used to stop a migraine attack that's already underway from getting worse. They also are used to help prevent migraines in women who tend to get them when they have their periods (a.k.a. menstrual migraines).

What is the CGRP antagonist?

There are two main categories of drugs for managing migraine headaches: those taken to prevent them from happening and those used for the acute treatment of a migra ine that's already underway. Doctors often refer to the latter as "abortive" medications. Under the umbrella of abortive migraine treatments are drugs ranging ...

How does CGRP work?

CGRP antagonists work by blocking the binding of cGRP to receptors in the brain, thereby minimizing vasodilation and neurogenic inflammation. Unlike other acute migraine medications, these drugs do not induce vasoconstriction, which means they may be a safer option for people who have increased cardiovascular risk. 7

What is the difference between Frova and Imitrex?

Frova (frovatriptan) Amerge (naratriptan) Maxalt, Maxalt-MLT (rizatriptan), which comes as a tablet or as a wafer that melts on the tongue. Imitrex ( sumatriptan ), which is available as a tablet, nasal spray, or subcutaneous (under-the-skin) injection.

What is an abortive migraine?

Under the umbrella of abortive migraine treatments are drugs ranging from over-the-counter (OTC) analgesics (painkillers) to prescription medications that treat not only the headache but also other migraine symptoms. Finding what works best for you can take some time and requires ...

Which antidepressant is most effective for migraines?

SSRIs are the latest generation of antidepressants and includes Paroxetine, Fluoxetine (Prozac) and Sertraline. Prozac has been proven most effective for people with chronic migraines, that is, migraines which occur 15 or more days per month.

What is the best beta blocker for migraines?

They can smooth out and shrink blood vessels in the head to reduce pain. The best beta blockers for migraine relief are Propranolol (Inderal) and Timolol.

What are the medications for migraines?

Medications in this category include Imitrex, Relpax, Amerge, Frova, Axert, Maxalt, and Zomig.

What is the best medicine for migraines?

They ease nausea and pain, as well as sensitivity to light and sound. • Butalbital, a sedative, is often combined with acetaminophen, aspirin, caffeine, or codeine to treat migraines. Narcotics like meperidine are also an option.

Is there a drug free migraine treatment?

A new study suggests that there may be a drug-free alternative to treating some migraines: a handheld transcranial magnetic stimulation device that, when held against the bottom of the back of the head, eased migraine symptoms in some study volunteers. While it will be months, at a minimum, before the new device reaches market, ...

What are the best migraine medications?

The classes of acute treatment migraine drugs include: 1 Analgesics treat pain and include both over-the-counter and prescription medicines. 2 Ergots work to balance brain chemicals and constrict blood vessels. Nausea is a common side effect. 3 Triptans work in much the same way as ergots. However, they are more specific for migraine. Common side effects may include flushing, tingling, sleepiness, and throat or chest tightness. 4 Small molecule CGRP blockers are not approved to prevent migraine but are effective for rapidly treating acute migraine episodes. They are an oral pill that can be taken with other migraine drugs.

What are the main classes of preventive treatment for migraines?

The main classes of preventive treatment migraine drugs include: Antidepressants also balance brain chemicals that play a role in migraine. Side effects vary depending on the drug. Anticonvulsants are drugs that treat seizures through various effects on the brain. Common side effects include sleepiness and weight changes.

What are the side effects of CGRP injections?

Common side effects include headache, neck pain, and pain at the injection site. Monoclonal antibody CGRP blockers are the first class of drugs specifically produced to prevent migraines. They block a molecule thought to instigate migraine and increase migraine pain and intensity. This drug is injected under the skin.

How long does it take for migraines to go away?

In general, your acute migraine medication should relieve your symptoms in four hours or less. You should be able to return to your daily routine within that time. If your headaches still interfere with your day, talk with your doctor. You may need to try different treatments to find the right one for you.

What is the difference between Eletriptan and Metoprolol?

It is a tablet you take at the onset of your migraine symptoms. For triptans, your doctor will tell you how many tablets you can take in a 24 hour period. Metoprolol ( Lopressor, Toprol XL) is a beta blocker. It comes in both an immediate-release and an extended-release form.

Why do women get migraines?

These headaches tend to happen more commonly in women compared to men. Your risk of migraine also increases if you have a family history of it. Common migraine triggers include hormone changes, stress, alcohol, and certain foods.

How long before headache do you have aura?

Sometimes, people have an aura up to 30 minutes before the headache. An aura can range from seeing flashing lights to tingling to mental fuzziness. During the migraine, you may have other migraine symptoms, such as nausea, vomiting, or sensitivity to light or sounds. Over 30 million Americans suffer from migraine headaches.

What is the drug class of Topamax?

Topamax (topiramate) Drug class: Anti-epileptics. Topiramate (Topamax) is an inexpensive drug used to treat seizures in adults or children with epilepsy. It is also used for the prevention of migraine headaches. It is slightly more popular than comparable drugs. It is available in brand and generic versions.

What is dihydroerogatomine used for?

DIHYDROERGOTAMINE is part of a group of medicines called ergot alkaloids. It is used to treat migraine headaches with or without aura. It should not be used to prevent migraine headaches.

What is Maxalt MLT?

Maxalt-Mlt (rizatriptan) Drug class: Triptans. Rizatriptan ( Maxalt, Maxalt-mlt) is a moderately priced drug used to treat migraines with or without aura. An aura is a strange feeling or visual disturbance that warns you of an attack. It is not used to prevent migraines.

What is Divalproex used for?

Divalproex ER is an expensive drug used to prevent seizures caused by some forms of epilepsy. It is also used to treat bipolar mania and to prevent migraine headaches. This drug is slightly less popular than other comparable drugs. It is available in brand and generic versions.

What is aura medicine?

An aura is a strange feeling or visual disturbance that warns you of an attack. It is not used to prevent migraines. It is slightly more popular than comparable drugs. It is available in generic and brand versions.

Is Inderal a generic drug?

It is slightly less popular than comparable drugs. Propranolol is only available as a generic drug; all brands have been discontinued. Generic propranolol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Is amitriptyline a generic drug?

Amitriptyline is used to treat depression. It is more popular than comparable drugs. Amitriptyline is only available as a generic drug; all brands have been discontinued. Generic amitriptyline is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Drugs used to treat Migraine

The following list of medications are in some way related to, or used in the treatment of this condition.

Alternative treatments for Migraine

The following products are considered to be alternative treatments or natural remedies for Migraine. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Migraine.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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