Treatment FAQ

what causes polymyalgia rheumatica treatment

by Prof. Gianni Heathcote V Published 3 years ago Updated 2 years ago
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Common Causes

Steroid treatment is usually very effective at treating polymyalgia rheumatica. However, because it can increase your risk of getting osteoporosis, it’s important to think about other risk factors associated with this condition. Smoking or drinking a lot of alcohol will increase your risk of developing osteoporosis.

Related Conditions

Cause of Polymyalgia Rheumatica and Giant Cell Arteritis Inflammation causes polymyalgia rheumatica and giant cell arteritis, but scientists do not know what triggers it. Some studies have linked certain gene variants with the disorders, but these genetic links have not been consistent across different populations.

How do I know if I have polymyalgia rheumatica?

Oct 14, 2021 · While the exact cause of polymyalgia rheumatica remains unknown, it is speculated that genetics and environmental exposure may have an effect on its onset. Genetics There are some specific genes and gene variations that may increase a person’s chances of developing polymyalgia rheumatica.

Is polymyalgia rheumatica very contagious?

Apr 12, 2022 · Polymyalgia rheumatica (PMR) is a disease that causes pain and stiffness in muscles and joints, low-grade fever, and weight loss. Health care professionals diagnose PMR by characteristic common symptoms associated with abnormal blood testing for inflammation. Treatment of PMR involves taking low doses of cortisone medications.

Does stress affect polymyalgia?

Mar 12, 2022 · Polymyalgia rheumatica sometimes occurs along with giant cell arteritis, a condition that causes swelling of the arteries in your head. Symptoms include headaches and blurred vision. Doctors often prescribe prednisone, a steroid medicine, for both conditions. With treatment, polymyalgia rheumatica usually disappears in a day or two.

What does polymyalgia feel like?

Jun 06, 2020 · The cause of polymyalgia rheumatica is unknown. It is thought there may be a genetic component since the condition is more common among northern Europeans. It may also be due to an autoimmune process, and some researchers believe nonerosive synovitis and tenosynovitis may be responsible for several symptoms of polymyalgia rheumatica.

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What triggers polymyalgia rheumatica?

The cause of polymyalgia rheumatica (PMR) is unknown. It is possible that the way the immune system responds to certain viruses may trigger the disease. It is most probable that its development is triggered by a combination of genetic and environmental factors.

Does polymyalgia rheumatica ever go away?

With treatment, PMR symptoms usually lessen or go away within days. Without treatment, they may go away after a year but could take up to five years or more. Proper nutrition, activity, rest and following medication regimens are important for managing the condition.

Is polymyalgia rheumatica a serious condition?

It sounds serious, even ferocious, but it responds beautifully to proper treatment. It's polymyalgia rheumatica (PMR), a painful, sometimes disabling condition that can be associated with giant cell arteritis (GCA), a disease that is much less common but much more serious.Nov 1, 2011

Can polymyalgia be brought on by stress?

Inflammatory conditions such as PMR can result or flare up from excessive stress.

Does heat help polymyalgia rheumatica?

Learn new ways to manage pain – there are many things you can do to manage pain – and different strategies will work for different situations. For example, heat packs can help ease muscle pain, cold packs can help with inflammation, gentle exercise can help relieve muscle tension.

What is the best pain relief for polymyalgia?

Medications. Corticosteroids. Polymyalgia rheumatica is usually treated with a low dose of an oral corticosteroid, such as prednisone (Rayos). You'll likely start to feel relief from pain and stiffness within the first two or three days.Jun 18, 2020

Can a blood test detect polymyalgia rheumatica?

Tests. There's no specific test for polymyalgia rheumatica, but it's likely that a series of blood tests will be done. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are blood tests that can be used to check the levels of inflammation in your body.

What does polymyalgia pain feel like?

The most common symptom of polymyalgia rheumatica (PMR) is pain and stiffness in the shoulder muscles, which develops quickly over a few days or weeks. You may also have pain in your neck and hips. Both sides of the body are usually affected. The stiffness is often worse first thing in the morning after you wake up.

Is PMR a form of arthritis?

Rheumatoid arthritis and polymyalgia rheumatica are the two most common systemic rheumatic diseases in adults. Polymyalgia rheumatica (PMR) occurs exclusively in people over the age of 50 years, in contrast to rheumatoid arthritis (RA) with typical onset between 30 and 50 years of age.Nov 16, 2020

What are the warning signs of temporal arteritis?

What are the symptoms of temporal arteritis?Fatigue.Fever.Jaw pain that may become worse after chewing.Tenderness at the scalp or temples.Vision problems, such as double vision, blurry vision, or transient (brief) vision loss; if this is not treated, it could be followed by permanent, irreversible vision loss.More items...•Jan 28, 2019

Can polymyalgia cause bowel problems?

Conclusions. Patients with polymyalgia may have perforated colonic diverticular disease which mimics their rheumatic pathology. In such cases steroid therapy, which is the mainstay of polymyalgia therapy, can be detrimental.Sep 6, 2010

Does polymyalgia affect the hands?

Symptoms may include muscle pain (myalgia) and stiffness in the neck, shoulders, upper arms, lower back, hips, and/or thighs. The lower arms, hands, lower legs, and feet (distal extremities) are not usually affected by this disorder.Jun 17, 1997

How to diagnose polymyalgia rheumatica?

There’s no specific test to diagnose polymyalgia rheumatica. Your doctor will make a diagnosis after listening to you talk about the history of your symptoms and by carrying out a physical examination. You’ll also have blood tests to check for any inflammation in your body, and to rule out other conditions.

How to tell if you have polymyalgia?

If you’re over 50 and have the following symptoms and signs your GP will probably diagnose polymyalgia rheumatica, and start treatment straight away: 1 new shoulder, neck, hip or thigh pain on both sides of the body, which has been present for at least two weeks 2 pain and stiff muscles in the shoulders, hips or thighs in the mornings that lasts at least 30 minutes 3 high levels of inflammation measured by blood tests 4 no evidence of rheumatoid arthritis, such as swollen joints, or positive blood tests.

What is PMR in medical terms?

Polymyalgia rheumatica (poly-my-al-ger ru-mah-ticker), or PMR, is a relatively common condition that causes stiffness and pain in muscles. The word ‘poly’ means many and the word ‘myalgia’ means muscle pain. It can start at any age from 50, but mainly affects people over the age of 70. More women are affected than men.

How long does it take for polymyalgia rheumatica to go away?

Normally, steroid treatment for polymyalgia rheumatica will be taken as tablets. Your symptoms may almost disappear after four weeks of steroid treatment. However, treatment usually needs to continue for up to two years, or occasionally longer, to stop the symptoms returning.

Can you feel pain after exercise?

The symptoms are different from the ache you may feel after exercise that your body isn’t used to. The pain and stiffness from polymyalgia rheumatica is often widespread, and is worse when resting or after rest. Symptoms can improve with activity or as the day goes on. The pain may also wake you at night.

Does alcohol cause osteoporosis?

However, because it can increase your risk of getting osteoporosis, it’s important to think about other risk factors associated with this condition. Smoking or drinking a lot of alcohol will increase your risk of developing osteoporosis.

What are some examples of painkillers?

Examples include alendronate and risedronate. Pain relief. Painkillers, such as paracetamol, or short courses of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, can help ease pain and stiffness. They can be taken at the same time as steroid tablets.

How do you know if you have polymyalgia rheumatica?

Symptoms. The signs and symptoms of polymyalgia rheumatica usually occur on both sides of the body and might include: Aches or pain in your shoulders. Aches or pain in your neck, upper arms, buttocks, hips or thighs. Stiffness in affected areas, particularly in the morning or after being inactive for a time. Limited range of motion in affected ...

What are the symptoms of giant cell arteritis?

Signs and symptoms include headaches, jaw pain, vision problems and scalp tenderness.

What are the symptoms of polymyalgia rheumatica?

Symptoms of polymyalgia rheumatica tend to start suddenly and may include: Pain and stiffness in the: Shoulders. Upper arms. Neck. Lower back. Hips. Thighs. The pain and stiffness tends to be worse in the morning.

How long does polymyalgia rheumatica last?

Treatment is generally necessary for at least six months. And it often continues for one to two years or even longer.

What is the condition that causes pain in the lower back, thighs, hips, neck, and upper arms?

Polymyalgia rheumatica is an inflammatory condition that causes pain in the joints and muscles of the lower back, thighs, hips, neck, shoulder and upper arms, and other parts of the body. The condition occurs when the lining surrounding the joints, bursa and tendons near the shoulders and hips becomes inflamed.

What is the best medicine for osteoporosis?

For example, calcium, vitamin D and alendronate ( Fosamax) may be prescribed to prevent osteoporosis. For people who have significant side effects from corticosteroids or when the dose of corticosteroids cannot be reduced to low doses without a return of symptoms, other drugs may be prescribed.

What does it mean when you have a headache and a fever?

The situation may be urgent if you have fever, visual problems or headache. These symptoms suggest that you could have giant cell arteritis.

Can polymyalgia rheumatica cause stiffness?

Left untreated, it can lead to stiffness and significant disability. In some cases, symptoms do not get worse. They may even lessen in a few years. In a minority of cases, polymyalgia rheumatica is associated with giant cell arteritis (also called temporal arteritis).

What are the symptoms of PMR?

This occurs in at least two of the following areas; hips, shoulders, neck, thigh, buttocks and upper arms. However, some people experience pain and/or stiffness in their hands or wrists as well ( x ).

What is the most common inflammatory rheumatic disease?

Polymyalgia rheumatica ( PMR) is the most common inflammatory rheumatic disease that effects the elderly. While any older adult can get PMR, it is most common in Caucasians over the age of 50. It typically impacts women more often than men ( x ). This inflammatory disorder can cause muscle pain and stiffness, typically around the shoulders and hips ...

How old is PMR?

PMR almost exclusively affects adults. The average age of onset is 70 years old and it is very rare for anyone under the age of 50 to develop PMR ( x ). This disorder is especially common in women and in Caucasians with ancestors from Scandinavia or Europe ( x ). Polymyalgia Rheumatica and Similar Disorders.

Is PMR a benign condition?

Most of the time PMR remains a benign condition that easily responds to treatment. However, in rare cases, permanent muscle weakness, atrophy (the degeneration and loss of muscle mass) and disability may occur ( x ).

What is temporal arteritis?

This is a chronic inflammatory disease also known as temporal arteritis. It involves panarteritis, which is the progressive inflammation of arteries in your body. About 30 percent of people who have PMR are also diagnosed with giant cell arteritis ( x ). Symptoms of GCA vary from person to person.

Is PMR the same as GCA?

Because PMR and GCA are so similar, researchers think that they may be possible variants of the same disease process ( x ).

Is there a cure for polymyalgia rheumatica?

While there is not one specific cure for polymyalgia rheumatica, treatment focuses on reducing overall pain and inflammation and decreasing stiffness, achiness and other symptoms. PMR normally requires long term treatment with glucocorticosteroids. This type of treatment improves the patient’s symptoms very quickly.

What are the symptoms of polymyalgia rheumatica?

A patient may have a healthy history until awakening one morning with stiffness and pain of muscles and joints throughout the body, particularly in the upper arms, hips, neck, and shoulders.

What is PMR in medical terms?

Facts you should know about polymyalgia rheumatica ( PMR) Muscle pain and joint stiffness are symptoms of polymyalgia rheumatica. Polymyalgia rheumatica (PMR) is a disease that causes pain and stiffness in muscles and joints, low-grade fever, and weight loss. Health care professionals diagnose PMR by characteristic common symptoms associated ...

What is the name of the disease that affects the muscles and joints?

Polymyalgia rheumatica is a disease of the muscles and joints characterized by muscle pain ( myalgia) and stiffness, affecting both sides of the body, and involving the shoulders, arms, neck, and buttock areas. People with the disease are typically over 50 years of age. Polymyalgia rheu matica is abbreviated PMR.

What is giant cell arteritis?

Giant cell arteritis, also called temporal arteritis or cranial arteritis, is a serious disease characterized by inflammation of the walls of the blood vessels ( vasculitis). The vessels affected are the arteries (hence the name "arteritis"). Giant cell arteritis occurs in 10%-15% of patients with polymyalgia rheumatica.

How long does it take to wean off prednisone?

Most patients are able to completely wean from the corticosteroid within several years. Some patients require longer-term medical treatment. Occasionally, patients have recurrence years after the symptoms have resolved. The ideal prednisone dosing regimen continues to be sought by clinical researchers.

Is a virus associated with cancer?

Theories include viral stimulation of the immune system in genetically susceptible individuals. Rarely, the disease is associated with a cancer.

Is giant cell arteritis a cancer?

Giant cell arteritis is a potentially more serious condition. It can also occur, as mentioned above, in association with a cancer. The prognosis in this setting is based on the ability to cure the cancer. The polymyalgia rheumatica symptoms resolve with resolution of the cancer.

What are the symptoms of polymyalgia rheumatica?

Symptoms of polymyalgia rheumatica include pain and stiffness in the shoulders, hips, and neck, usually on both sides of the body. Characteristics of the pain and stiffness include: Stiffness may be severe and patients may have difficulty standing up from sitting, getting up from the toilet, turning over in bed, getting out of bed, ...

How long does polymyalgia rheumatica last?

Polymyalgia rheumatica is usually self-limiting and often goes away within several months to 5 years and is not generally associated with serious complications. Complications of polymyalgia rheumatica may include: Diminished quality of life if the condition is not treated. Side effects and complications from long-term corticosteroid therapy.

What is the condition that causes pain and stiffness in the neck and shoulders?

What Is Polymyalgia Rheumatica? Symptoms of polymyalgia rheumatica include pain and stiffness in the shoulders, hips, and neck, usually on both sides of the body. Polymyalgia rheumatica is a common chronic inflammatory condition that causes stiffness and aches in the shoulders, neck, and hips, and typically affects people aged 50 and older.

What are the symptoms of a stiffness in the morning?

Morning stiffness for more than 1 hour is common. Swelling of the arms or legs. Swelling of peripheral joints. Limited range of motion in the hips or shoulders. Other systemic symptoms include: Fever. Weight loss. Feeling unwell (Malaise) Fatigue.

Is polymyalgia rheumatica genetic?

It is thought there may be a genetic component since the condition is more common among northern Europeans. It may also be due to an autoimmune process, and some researchers believe nonerosive synovitis and tenosynovitis may be responsible for several symptoms of polymyalgia rhe umatica.

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Lifestyle and Home Remedies

Pain or tenderness in one or more muscles which can involve any area of the body.

Common Causes

Muscle pain is not always related to an underlying condition. It may be caused by:

  • Stress
  • Overuse of particular muscle group
  • Repetitive strain injuries
  • Sprains and strains
  • Excessive physical activity
  • Infections
Related Conditions
Sometimes muscle pain may signify an underlying health condition. These conditions include:

Coping and Support

Preparing For Your Appointment

Overview

  • Over-the-counter nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve), are not usually recommended for easing the signs and symptoms of polymyalgia rheumatica. Healthy lifestyle choices can help you manage the side ef…
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Symptoms

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Causes

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Risk Factors

  • Polymyalgia rheumatica is an inflammatory disorder that causes muscle pain and stiffness, especially in the shoulders and hips. Signs and symptoms of polymyalgia rheumatica (pol-e-my-AL-juh rue-MAT-ih-kuh) usually begin quickly and are worse in the morning. Most people who develop polymyalgia rheumatica are older than 65. It rarely affects people under 50. This conditi…
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Complications

  • The signs and symptoms of polymyalgia rheumatica usually occur on both sides of the body and might include: 1. Aches or pain in your shoulders 2. Aches or pain in your neck, upper arms, buttocks, hips or thighs 3. Stiffness in affected areas, particularly in the morning or after being inactive for a time 4. Limited range of motion in affected areas 5. Pain or stiffness in your wrists…
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The Mayo Clinic Experience and Patient Stories

  • The exact cause of polymyalgia rheumatica is unknown. Two factors appear to be involved in the development of this condition: 1. Genetics.Certain genes and gene variations might increase your susceptibility. 2. An environmental exposure.New cases of polymyalgia rheumatica tend to come in cycles, possibly developing seasonally. This suggests that an environmental trigger, such as …
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What Is Polymyalgia Rheumatica?

  • Risk factors for polymyalgia rheumatica include: 1. Age.Polymyalgia rheumatica affects older adults almost exclusively. It most often occurs between ages 70 and 80. 2. Sex.Women are about two to three times more likely to develop the disorder. 3. Race.Polymyalgia rheumatica is most common among white people whose ancestors were from Scandinavia or northern Europe.
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Symptoms

  • Symptoms of polymyalgia rheumatica can greatly affect your ability to perform everyday activities, such as: 1. Getting out of bed, standing up from a chair or getting out of a car 2. Combing your hair or bathing 3. Getting dressed These difficulties can affect your health, social interactions, physical activity, sleep and general well-being.
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Diagnosis

  • Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.
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Expected Duration

  • Polymyalgia rheumatica is an inflammatory condition that causes pain in the joints and muscles of the lower back, thighs, hips, neck, shoulder and upper arms, and other parts of the body. The condition occurs when the lining surrounding the joints, bursa and tendons near the shoulders and hips becomes inflamed. The disease is centered on the joints (especially the shoulders and hips…
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Treatment

  • Symptoms of polymyalgia rheumatica tend to start suddenly and may include: 1. Pain and stiffness in the: 1.1. Shoulders 1.2. Upper arms 1.3. Neck 1.4. Lower back 1.5. Hips 1.6. Thighs The pain and stiffness tends to be worse in the morning. 1. Low-grade fever 2. Joint swelling 3. Difficulty walking 4. Weight loss 5. Fatigue
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When to Call A Professional

  • Your doctor will diagnose this condition based on a combination of: 1. Your description of symptoms 2. A physical examination, and 3. Test results Certain symptoms may suggest the presence of giant cell arteritis. These include scalp pain, headache, fever, or jaw pain when you chew. An erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) blood test may b…
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Prognosis

  • Without treatment, polymyalgia rheumatica sometimes goes away on its own over several years. With treatment, symptoms lessen or go away within days. Treatment is generally necessary for at least six months. And it often continues for one to two years or even longer. Symptoms tend to come back if you stop or decrease your treatment.
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Further Information

  • Treatment usually begins with nonsteroidal anti-inflammatory drugs (NSAIDs). These include ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn). However, they are rarely very helpful. Corticosteroids, such as prednisone, usually are required to effectively treat polymyalgia rheumatica. Low doses (such as prednisone, 10 mg to 20 mg per day) are highly effective. Doct…
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