Treatment FAQ

what are the treatment options for bipolar disorder

by Prof. Aurelio Auer Published 3 years ago Updated 2 years ago
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The primary treatments for bipolar disorder include medications and psychological counseling (psychotherapy) to control symptoms, and also may include education and support groups.
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Medications
  • Mood stabilizers. ...
  • Antipsychotics. ...
  • Antidepressants. ...
  • Antidepressant-antipsychotic. ...
  • Anti-anxiety medications.
Feb 16, 2021

Medication

  • The goal of maintenance treatment is to prevent future manic or depressive episodes.
  • Because of the relapsing and remitting nature of bipolar I disorder, maintenance treatment is indicated after the first manic episode.
  • The focus of maintenance treatment is long-term medication management, psychotherapy, and lifestyle changes.

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Therapy

Treatment

  • Medications. A number of medications are used to treat bipolar disorder. ...
  • Finding the right medication. Finding the right medication or medications for you will likely take some trial and error. ...
  • Side effects. ...
  • Medications and pregnancy. ...
  • Psychotherapy. ...
  • Other treatment options. ...
  • Treatment in children and teenagers. ...

Which type of therapy is best for treating bipolar disorder?

Medications for bipolar disorder include lithium, anticonvulsants, antipsychotics, antidepressants, and ketamine. Learn about their side effects and benefits.

What is the most typical treatment for bipolar disorder?

Important things to know before getting treatment for bipolar disorder include:

  • there are specially trained mental health professionals such as psychiatrists and psychologists who can help you with bipolar disorder
  • you need a thorough check from a health professional before treatment is prescribed
  • specially prescribed medication is the most effective way to treat and manage bipolar disorder

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What are the most common medications for bipolar disorder?

What should I include in my Bipolar disorder treatment plan?

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What is the best treatment for bipolar disorder?

The most effective treatment for bipolar disorder is a combination of medication and psychotherapy. Most people take more than one drug, like a mood-stabilizing drug and an antipsychotic or antidepressant.

What are two treatment options for bipolar disorder?

In addition to medication for bipolar disorder, other treatment approaches include:Psychotherapy. ... Substance abuse treatment. ... Treatment programs. ... Self-management strategies.

Can bipolar be treated without medication?

Counseling, cognitive behavioral therapy (CBT), and a range of lifestyle changes can help people with bipolar disorder to manage their symptoms and improve their overall quality of life.

What is the first choice treatment for bipolar disorder?

Lithium. Lithium is the first-line choice for preventing mood instability and treating mania. This agent is successful in treating aggressive behavior during acute manic episodes, and it is also the most successful long-term treatment for bipolar disorder.

What are 3 treatments for bipolar disorder?

The primary treatments for bipolar disorder include medications and psychological counseling (psychotherapy) to control symptoms, and also may include education and support groups....MedicationsMood stabilizers. ... Antipsychotics. ... Antidepressants. ... Antidepressant-antipsychotic. ... Anti-anxiety medications.

How do psychologists treat bipolar disorder?

Cognitive behavioral therapy focuses on a person's thoughts and actions, and helps them change unhealthy behavior patterns. It can help people cope with the symptoms of bipolar disease and recognize signs of an impending mood shift.

Does bipolar worsen with age?

Changes in the frequency and severity of episodes are among the most evident changes in bipolar disorder at an older age. Research suggests that older adults with bipolar disorder often experience: more frequent episodes. more depressive episodes and less time spent in manic or hypomanic states.

What happens if bipolar is untreated?

When left untreated, the symptoms of Bipolar Disorder will often increase in severity and may lead to suicide; there is a high suicide rate for people with the disorder. When treated, it's possible to control the symptoms of Bipolar Disorder and enjoy a more stable and fulfilling life.

At what age does bipolar disorder most frequently emerge?

Although bipolar disorder can occur at any age, typically it's diagnosed in the teenage years or early 20s. Symptoms can vary from person to person, and symptoms may vary over time.

What are 5 signs of bipolar?

Symptoms - Bipolar disorderfeeling sad, hopeless or irritable most of the time.lacking energy.difficulty concentrating and remembering things.loss of interest in everyday activities.feelings of emptiness or worthlessness.feelings of guilt and despair.feeling pessimistic about everything.self-doubt.More items...

What is the best mood stabilizer for bipolar?

Lithium: The first mood stabilizer for bipolar disorder. Mood stabilizers are medications that help control the highs and lows of bipolar disorder. They are the cornerstone of treatment, both for mania and depression. Lithium is the oldest and most well-known mood stabilizer and is highly effective for treating mania.

What is the most common medication for bipolar disorder?

Lithium. In the UK, lithium is the main medicine used to treat bipolar disorder. Lithium is a long-term treatment for episodes of mania and depression. It's usually prescribed for at least 6 months.

What is the best treatment for bipolar disorder?

Bipolar disorder is treated with three main classes of medication: mood stabilizers, antipsychotics, and, while their safety and effectiveness for the condition are sometimes controversial, antidepressants.

How to help bipolar patients?

While medications are usually the cornerstone of treatment for bipolar disorder, ongoing psychotherapy is important to help patients understand and accept the personal and social disruptions of past episodes and better cope with future ones. Several specific forms of psychotherapy have been shown to help speed recovery and improve functioning in bipolar disorder, including cognitive-behavioral therapy, interpersonal/social rhythm therapy, family therapy, and group therapy. In addition, because denial is often a problem -- sticking with medications can be especially tricky in adolescence -- routine psychotherapy helps patients stay on their medications.

What is the best medication for mania?

Haloperidol ( Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole ( Abilify ), asenapine ( Saphris ), olanzapine ( Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis ) or risperidone ( Risperdal ), are often given to patients as an alternative to lithium or divalproex. They also may be given to treat acute symptoms of mania -- particularly psychosis -- before lithium or divalproex ( Depakote) can take full effect, which may be from one to several weeks. Another antipsychotic, lurasidone (Latuda ), is approved for use in bipolar I depression as is the combination of olanzapine plus fluoxetine (called Symbyax ). The antipsychotic quetiapine ( Seroquel) is approved to treat bipolar I or II depression . Preliminary studies also suggest that the atypical antipsychotic cariprazine ( Vraylar) also may have value for treating bipolar depression

What is the most important thing to know about bipolar?

IMPORTANT! Help and Support. In the manic phase of bipolar disorder, patients may engage in risky activities, such as fast driving or certain risky sports. They should be monitored and prevented from taking chances, especially in a car.

How to help someone with bipolar disorder?

If someone you live with has bipolar disorder, maintain a calm environment, particularly when that person is in a manic phase. Keep to regular routines for daily activities -- sleeping, eating, and exercise. Adequate sleep is very important in preventing the onset of episodes. Avoid excessive stimulation.

What are the different types of depression?

The newer types of nonpharmocological treatments of depression are: 1 VNS (Vagus or Vagal Nerve Stimulation) involves implantation of a device that sends electrical signals to the vagus nerve in order to treat depression. 2 TMS (Transcranial Magnetic Stimulation) is a procedure which involves the use of an electromagnetic coil to create electrical currents and stimulate nerve cells in the mood centers of the brain as a treatment for depression. 3 Light therapy has proved effective as an additional treatment when bipolar disorder has a connection to seasonal affective disorder. For those people who usually become depressed in winter, sitting for 20 minutes to 30 minutes a day in front of a special light box with a full-spectrum light can help treat depression.

What is the best antiepileptic drug for depression?

Lamotrigine ( Lamictal), another antiepileptic drug, has been shown to have value for preventing depression and, to a lesser degree, manias or hypomanias. Other antiepileptic drugs, such as gabapentin ( Neurontin), oxcarbazepine ( Trileptal ), or topiramate ( Topamax ), are regarded as experimental treatments that sometimes have value ...

Bipolar Disorder

Cognitive behavioral therapy is one method of treatment for manic depression.

Medication Treatments

Medications used in the treatment of bipolar disorder work to stabilize a person’s extreme mood states. Some medications are used to target the symptoms of the disorder head-on, while others may be used to treat individual symptoms, such as depression and anxiety.

Cognitive Behavioral Therapy

As with any other type of psychological condition, people with bipolar disorder develop unhealthy and/or unproductive coping behaviors to compensate for their symptoms. Over time, these coping behaviors affect the way a person views his or her role within relationship interactions with friends and family.

What is the best treatment for bipolar disorder?

Lithium, introduced by John Cade in 1949, remains the best established long-term treatment for bipolar disorder.49Although the metal has been in clinical use for more than 50 years, the most convincing evidence of long-term efficacy comes from randomised clinical trials in which lithium was included as an active comparator.50A meta-analysis of five placebo-controlled lithium maintenance trials (n=770) showed that lithium reduces the risk of manic relapses by 38% (RR 0·62, 95% CI 0·50–0·84) and depressive relapse by 28% (0·72, 0·40–0·95).50Lithium is the only known anti-suicidal treatment with randomised evidence of a reduction in the risk of suicide of more than 50%.51However, the benefits of lithium are restricted by adverse effects and a low therapeutic index.52Although little evidence exists of a clinically substantial reduction in renal function in most patients, the risk of end-stage renal failure remains unclear. The risk of congenital malformations in the babies of mothers who have taken lithium during pregnancy is uncertain, but probably lower than previously thought. The balance of risks should be considered before lithium is withdrawn during pregnancy. In addition to known effects of lithium on the thyroid, the risk of hyperparathyroidism is increased and calcium concentrations should be checked before and during treatment.52

How to treat bipolar disorder?

Treatment of bipolar disorder conventionally focuses on acute stabilisation, in which the goal is to bring a patient with mania or depression to a symptomatic recovery with euthymic (stable) mood; and on maintenance, in which the goals are relapse prevention, reduction of subthreshold symptoms, and enhanced social and occupational functioning. Treat ment of both phases of the illness can be complex, because the same treatments that alleviate depression can cause mania, hypomania, or rapid cycling (defined as four or more episodes in 12 months), and the treatments that reduce mania might cause rebound depressive episodes.

How long do bipolar patients stay depressed?

Up to a third of patients with bipolar disorder do not respond to treatments in naturalistic studies;4,5,7these figures probably underestimate the proportion of treatment-resistant patients with depression in clinical practice. Even patients who receive adequate pharmacotherapy have lengthy and debilitating periods of subthreshold depressive symptoms after major episodes. Longitudinal studies estimate that patients with bipolar disorder type I spend as many as 3 weeks depressed for every 1 week (hypo)manic; the ratio in bipolar disorder type II is 37:1.5,44Subthreshold depressive symptoms are associated with social and occupational impairment,45and increased psychosocial impairment is prospectively associated with earlier recurrences.46,47

How many people have bipolar disorder?

Bipolar disorders types I and II affect about 2% of the world’s population, with subthreshold forms of the disorder affecting another 2%.1–2Even with treatment, about 37% of patients relapse into depression or mania within 1 year, and 60% within 2 years.3In the STEP-BD cohort (n=1469), 58% of patients with bipolar disorder types I and II achieved recovery, but 49% had recurrences in a 2-year interval; twice as many of these recurrences were of depressive polarity (marked by sad mood, loss of interests, or fatigue) rather than of manic polarity (marked by elevated mood, grandiosity, and decreased need of sleep).4After initial onset, patients with bipolar disorder have residual depressive symptoms for about a third of the weeks of their lives.5In 2009, the direct and indirect costs of bipolar disorder were estimated to be US$151 billion.6Patients also experience psychotic symptoms, impaired functioning, compromised quality of life, and stigma.7,8

How can depression be enhanced?

Long-term maintenance and possibly acute stabilisation of depression can be enhanced by the combination of psychosocial treatments with drugs. The development of future treatments should consider both the neurobiological and psychosocial mechanisms underlying the disorder.

When was lithium first used for mania?

Open in a separate window. Treatment of mania. The pioneering trials of lithium and chlorpromazine were done in the 1970s and were followed by a focus on antiepileptics (eg, valproate and carbamazepine) in the 1980s and 1990s.

Which antidepressants modulate glutamate transmission?

Valproate, lamotrigine, and some antidepressants modulate glutamate transmission; rapid alleviation of

What is the best treatment for bipolar disorder?

Psychotherapy. Psychotherapy, support groups and psychoeducation about the illness are essential to treating bipolar disorder: Cognitive behavioral therapy (CBT) helps change the negative thinking and behavior associated with depression.

How does bipolar affect people?

Bipolar Disorder. Proper treatment helps most people living with bipolar disorder control their mood swings and other symptoms. Because bipolar disorder is a chronic illness, treatment must be ongoing. If left untreated, the symptoms of bipolar disorder get worse, so diagnosing it and beginning treatment early is important.

What is a second generation antipsychotic?

Second-Generation Antipsychotics (SGAs) SGAs are commonly used to treat the symptoms of bipolar disorder and are often paired with other medications, including mood stabilizers. They are generally used for treating manic or mixed episodes. SGAs are often prescribed to help control acute episodes of mania or depression.

Can antidepressants cause bipolar disorder?

Antidepressants present special concerns when used in treating bipolar disorder, as they can trigger mania in some people. A National Institute of Mental Health study showed that taking an antidepressant also to a mood stabilizer is no more effective that using a mood stabilizer alone for bipolar I.

Can bipolar disorder be better treated with medication?

With the prescribing doctor, work together to review the options for medication. Different types of bipolar disorder may respond better to a particular type. The side effects can vary between medications and it may take time to discover the best medicine.

Can bipolar affect a woman's pregnancy?

Women. Women with bipolar disorder who are of childbearing age, or who are considering getting pregnant, need special attention. A complex risk- benefit discussion needs to occur to look at the treatment options available . Some medicines can have risk to the developing fetus and to children in breast milk. However, there is also evidence that being off of all medications increases the likelihood of bipolar symptoms, which itself creates risks to both mother and fetus or baby. Planning ahead and getting good information from your health care team based on your individual circumstances improves your chance of a best outcome.

Does lithium cause bipolar?

Lithium (Lithobid, Eskalith) is effective at stabilizing mood and preventing the extreme highs and lows of bipolar disorder. Periodic blood tests are required because lithium can cause thyroid and kidney problems. Common side effects include restlessness, dry mouth and digestive issues. Lithium levels should be monitored carefully to ensure the best dosage and watch for toxicity.

What is the best treatment for bipolar disorder?

Other therapeutic methods are also available for the treatment of bipolar disorder. Interpersonal and social rhythm therapy is one such option. The goals of this type of therapy are to help improve the patient’s relationships with others and help him learn to manage his daily routines.

How to help someone with bipolar disorder?

Support programs are another important part of treating bipolar disorder, including cognitive behavioral therapy treatment . This therapy involves retraining your brain to think and react differently to situations. Many people suffering from this disorder may find they are able to benefit from speaking with others who are experiencing the same challenges and symptoms. One of the goals of such treatment programs is to assist you in learning how to cope with the symptoms you may experience.

What is electroconvulsive therapy?

In cases in which psychotherapy and medication have not been successful, electroconvulsive therapy may be used. In the past, this type of therapy was referred to as shock therapy and once had a bad reputation. The National Institute of Mental Health reports that this form of therapy has been significantly improved in the last few years, and it is now used to provide relief for individuals who suffer from severe symptoms related to bipolar disorder. This form of therapy may also be used when other forms of treatment are considered too risky, such as when a patient is pregnant and not able to take prescription medications. Although electroconvulsive therapy is not typically used as a first-line treatment, it has been shown to be effective for mixed, manic or severe episodes.

What is the treatment for manic depression?

Therapies for manic depression can be far reaching and may include cognitive behavioral therapy as well as medications. Medicines are often considered an integral component in treating bipolar disorder. Mood stabilizers are often among the first medications to be used in the treatment of this disorder.

How long does a manic phase last?

For instance, if you are experiencing a manic phase, you might notice such symptoms as the following: The manic phase of bipolar disorder can last for weeks or even go on for months. When an individual is in the middle of a depressive episode, he may have difficulty concentrating or making decisions.

Why is medical supervision important for bipolar disorder?

Due to the risk for self-harm that accompanies bipolar disorder, such medical supervision is critical, particularly if you are experiencing a depressive episode. In addition, medical staff will be available to assist you in regulating your daily schedule, including your sleep schedule.

What is bipolar disorder?

Bipolar disorder, sometimes referred to as manic-depressive disorder, is a type of brain disorder that results in changes in activity levels, energy and mood. Individuals who suffer from this disorder may experience difficulty in carrying out everyday tasks. Bipolar disorder treatment program options are ...

What are some ways to help with bipolar disorder?

massage therapy. yoga. acupuncture. meditation. Calming techniques can’t cure bipolar disorder. But they may help you manage your symptoms and be a valuable part of your treatment plan. 9. Interpersonal and social rhythm therapy (IPSRT) Erratic patterns and sleep deprivation may worsen symptoms of bipolar disorder.

What are the best foods to help with bipolar?

1. Fish oil. Fish oil and fish are common sources of two of the three main types of omega-3 fatty acids: These fatty acids may affect the chemicals in your brain associated with mood disorders. Bipolar disorder seems to be less common in countries where people consume fish and fish oil.

How long does inositol help with bipolar?

, 66 people with bipolar disorder who were experiencing a major depressive episode that was resistant to a combination of mood stabilizers and one or more antidepressants, were also given inositol or another additional therapy for up to 16 weeks.

How to reduce manic episodes?

maintain a regular routine. adopt good sleep habits. learn how to solve problems that interrupt their routine. IPSRT, in addition to your prescribed medications for bipolar disorder, may help to reduce the number of manic and depressive episodes you have. 10. Lifestyle changes.

How to improve mood and reduce irritability?

Adequate sleep can help stabilize your mood and reduce irritability. Tips to improve sleep include establishing a routine and creating a calm bedroom environment.

Can alternative treatments be used for bipolar disorder?

Alternative treatments shouldn’t replace your current treatment or medication for bipolar disorder.

Does fish oil help with bipolar?

Bipolar disorder seems to be less common in countries where people consume fish and fish oil. People with depression also tend to have lower levels of omega-3 fatty acids in their blood. Omega-3 fatty acids may help:

What is the best medication for bipolar disorder?

Medications generally used to treat bipolar disorder include mood stabilizers and second-generation (“atypical”) antipsychotics. Treatment plans may also include medications that target sleep or anxiety. Health care providers often prescribe antidepressant medication to treat depressive episodes in bipolar disorder, combining the antidepressant with a mood stabilizer to prevent triggering a manic episode.

How to help someone with bipolar disorder?

Proper diagnosis and treatment can help people with bipolar disorder lead healthy and active lives. Talking with a doctor or other licensed health care provider is the first step. The health care provider can complete a physical exam and order necessary medical tests to rule out other conditions. The health care provider may then conduct a mental health evaluation or provide a referral to a trained mental health care provider, such as a psychiatrist, psychologist, or clinical social worker who has experience in diagnosing and treating bipolar disorder.

How does electroconvulsive therapy work?

Electroconvulsive Therapy (ECT): ECT is a brain stimulation procedure that can help people get relief from severe symptoms of bipolar disorder. With modern ECT, a person usually goes through a series of treatment sessions over several weeks. ECT is delivered under general anesthesia and is safe. It can be effective in treating severe depressive and manic episodes, which occur most often when medication and psychotherapy are not effective or are not safe for a particular patient. ECT can also be effective when a rapid response is needed, as in the case of suicide risk or catatonia (a state of unresponsiveness).

How long does a manic period last?

Less severe manic periods are known as hypomanic episodes. Bipolar I Disorder— defined by manic episodes that last at least 7 days, or by manic symptoms that are so severe that the person needs immediate hospital care. Usually, depressive episodes occur as well, typically lasting at least 2 weeks.

What is bipolar 2?

Bipolar II Disorder— defined by a pattern of depressive episodes and hypomanic episodes, but not the full-blown manic episodes that are typical of Bipolar I Disorder.

Why is it important to take a medical history of bipolar disorder?

Taking a careful medical history is essential to ensure that bipolar disorder is not mistaken for major depression. This is especially important when treating an initial episode of depression as antidepressant medications can trigger a manic episode in people who have an increased chance of having bipolar disorder.

What are the symptoms of bipolar disorder?

Signs and Symptoms. People with bipolar disorder experience periods of unusually intense emotion, changes in sleep patterns and activity levels, and uncharacteristic behaviors —often without recognizing their likely harmful or undesirable effects. These distinct periods are called “mood episodes.”.

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Diagnosis

Treatment

Clinical Trials

Lifestyle and Home Remedies

Medically reviewed by
Dr. Abhimanyu Chandak
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Bipolar disorder lasts for a lifetime, with treatments aiming at managing the symptoms by psychotherapy and medication.
Medication

Mood stabilizers: Helps control extreme mood variations.

Carbamazepine . Lamotrigine . Valproate


Antipsychotic drugs: Help reduce symptoms of psychosis such as illusion, hallucination, etc.

Olanzapine . Quetiapine . Lurasidone . Cariprazine


Antidepressants: Helps stabilize the mood swings.

Sertraline . Fluoxetine . Citalopram . Desvenlafaxine . Duloxetine . Levomilnacipran . Venlafaxine


Antianxiety drugs: Reduces anxiousness.

Alprazolam . Clonazepam . Diazepam . Lorazepam . Oxazepam

Therapy

Psychotherapy:Interpersonal and social rhythm therapy, cognitive behavioral therapy, Psychoeducation and Family-focused therapy are used.

Electroconvulsive therapy (ECT):Passing mild electrical current to the brain to alter its chemistry and functioning. Usually given in severe cases.

Transcranial magnetic stimulation (TMS):Applying a magnetic field to the brain to alter its functions; still being tested. Usually given in severe cases.

Specialist to consult

Psychiatrist
Specializes in the branch of medicine concerned with the diagnosis and treatment of mental illness.

Alternative Medicine

  • To determine if you have bipolar disorder, your evaluation may include: 1. Physical exam.Your doctor may do a physical exam and lab tests to identify any medical problems that could be causing your symptoms. 2. Psychiatric assessment.Your doctor may refer you to a psychiatrist, who will talk to you about your thoughts, feelings and b…
See more on mayoclinic.org

Preparing For Your Appointment

  • Treatment is best guided by a medical doctor who specializes in diagnosing and treating mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. You may have a treatment team that also includes a psychologist, social worker and psychiatric nurse. Bipolar disorder is a lifelong condition. Treatment is directed at managing symptoms. Depending on your needs, treatment may include: 1. Medications.Often, you'll n…
See more on mayoclinic.org

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