Treatment FAQ

what are the latest treatment options for middle aged people with traumatic brain injury

by Mr. Jarred Stehr Jr. Published 1 year ago Updated 1 year ago

Medication

Treatment is based on the severity of the injury. Mild traumatic brain injuries usually require no treatment other than rest and over-the-counter pain relievers to treat a headache. However, a person with a mild traumatic brain injury usually needs to be monitored closely at home for any persistent, worsening or new symptoms.

Procedures

Even patients over the age of 75 may recover from severe traumatic brain injury, suggests new research. This is the first study to describe the results of surgically treated elderly patients with acute subdural hematomas.

Therapy

Patients who are fully independent before the injury with good mental and physical status would usually be given active treatment including acute surgery.

Nutrition

Moderate TBI —loss of consciousness for more than 30 minutes, but less than 24 hours; or confused or disoriented state lasting more than 24 hours; or memory loss lasting more than 24 hours but less than 7 days; or meets criteria for concussion/mild TBI but with an abnormal CT. Excludes penetrating TBI.

What is the treatment for a traumatic brain injury?

Can the elderly recover from traumatic brain injury?

When is active treatment indicated in the treatment of traumatic brain injury?

What is considered moderate traumatic brain injury?

What are the latest treatments for TBI?

Recent reviews have identified several therapeutic classes showing promise for the treatment of TBI [25]. These includes erythropoietin (EPO), carbamylated form of EPO (CEPO), statins, bone marrow stromal cells (MSC), methylphenidate, progesterone, dexanabinol, and rivastigmine [25].

What type of treatments are available for TBI survivors?

Your individual program may include any or all of these treatments:Physical therapy.Physical medicine.Occupational therapy.Psychiatric care.Psychological care.Speech and language therapy.Social support.

What is the life expectancy after traumatic brain injury?

These changes may affect a person's ability to function in their everyday life. Despite initial hospitalization and inpatient rehabilitation services, about 50% of people with TBI will experience further decline in their daily lives or die within 5 years of their injury.

What is the initial treatment for patients with moderate to severe traumatic brain injury?

The treatment of moderate and severe head injuries begins with initial cardiopulmonary stabilization by ATLS guidelines. The initial resuscitation of a patient with a head injury is of critical importance to prevent hypoxia and hypotension.

Can you fully recover from a traumatic brain injury?

Therefore, a full and functional TBI recovery is almost always possible, even though it might take several years of dedication. But in order to make this type of progress, you must take initiative. In fact, without consistent work, brain injury recovery can stall and even regress.

What is the best medication for brain injury?

Anti-convulsants can sometimes prevent the spread of a seizure within the brain and offer protection against possible excitotoxic (excessive stimulation by chemicals in the nervous system) effects that may result in brain damage. Examples include: sodium valproate, gabapentin, topiramate and carbamazepine.

Does TBI get worse with age?

The short answer is yes. Some brain injuries do get worse over time. Secondary brain injuries are complications that arise after the initial injury, such as hematomas or infections.

Do traumatic brain injuries get worse with age?

People with a moderate or severe traumatic brain injury can experience increased musculoskeletal deterioration with aging, more than occurs in the general non-traumatic brain injury population.

Can a TBI get worse with time?

TBI symptoms often develop and get worse over time. Worsening symptoms can persist for months or years after head trauma and greatly affect quality of life. Traumatic brain injury can be a risk factor for psychiatric problems and diseases of the nervous system such as Alzheimer's Disease and Parkinson's Disease.

What are the long term effects of a traumatic brain injury?

Traumatic Injury Long-term Effects “Trauma to the left side of your brain can cause problems with logic, speech difficulties, trouble understanding others or talking, versus right side injury, which can cause problems processing visual information, neglect, or apraxia - the ability to perform regular or familiar tasks.

What are the top 5 medicines for head trauma?

Head Injury MedicationOsmotic diuretics.Anticonvulsants.Electrolytes.Barbiturates.Calcium Channel Blocker.Stimulants.Dopamine agonist.Selective serotonin reuptake inhibitors.More items...•

What are the 4 types of traumatic brain injuries?

Types of TBIsConcussions.Contusions.Penetrating injuries.Anoxic brain injuries.

What are the long term effects of a traumatic brain injury?

Traumatic Injury Long-term Effects “Trauma to the left side of your brain can cause problems with logic, speech difficulties, trouble understanding others or talking, versus right side injury, which can cause problems processing visual information, neglect, or apraxia - the ability to perform regular or familiar tasks.

What are two forms of treatment for a concussion?

Physical and mental rest Your doctor will recommend that you physically and mentally rest to recover from a concussion. Relative rest, which includes limiting activities that require thinking and mental concentration, is recommended for the first two days after a concussion.

What is the best way to recover from a TBI?

If you have had a TBI, rehabilitation (or rehab) will be an important part of your recovery. Rehab can take many forms depending on your needs, and might include physical, occupational, and speech therapy, as well as psychiatric care and social support. All of these are designed to help you recover from the effects of your injury as much as possible.

What to do before rehab for TBI?

Before you can start rehab, you must get care and treatment for the early effects of TBI. This might include: Emergency treatment for head and any other injuries. Intensive care treatment. Surgery to repair brain or skull injuries. Recovery in the hospital . Transfer to a rehabilitation hospital.

What is a case coordinator after TBI?

Every person's needs and abilities after TBI are different. You will have a rehab program designed especially for you. Your program is likely to involve many types of healthcare providers. It’s important to have one central person you can talk to. This person is often called your case coordinator.

What is the difference between a closed head injury and a penetrating head injury?

Traumatic brain injury (TBI) occurs when a sudden injury causes damage to your brain. A "closed head injury" may cause brain damage if something hits your head hard but doesn’t break through your skull. A "penetrating head injury" occurs when an object breaks through your skull and enters your brain.

Why should primary care providers be given all the records and recommendations from your therapy team?

Your primary care provider should be given all the records and recommendations from your therapy team to help ensure that you continue to get the right care.

What are the symptoms of a TBI?

Symptoms that may occur after TBI may include: Headaches. Dizziness. Confusion. Convulsions. Loss of coordination. Slurred speech. Poor concentration.

What are the causes of TBI?

According to the CDC, the leading cause of TBI is falls, particularly for young children and adults over 65. Other common causes of TBI include accidental blunt force trauma, motor vehicle accidents, and violent assaults.

The management of elderly patients with severe traumatic brain injury

The elderly population is defined by the World Health Organization as those aged over 65 years. Life expectancy has gradually increased but as the population of the elderly has progressively increased so has the incidence of traumatic brain injury (TBI).

Publication

How aggressively should neurosurgeons treat elderly patients with severe blunt traumatic brain injury? Rosenfeld JV, Tee JW Injury. 2015 Sep

Is surgery based on age alone?

According to Raj, the study throws new light on the old assumption that surgical treatment of the elderly is not a sensible course of action: "The decision to treat through surgery should not be based on age alone, even though this is common."

Can the elderly recover from a brain injury?

Even the elderly can recover from a severe traumatic brain injury. Even patients over the age of 75 may recover from severe traumatic brain injury, suggest s new research. This is the first study to describe the results of surgically treated elderly patients with acute subdural hematomas.

Can subdural hematoma be applied to contusions?

This means that the results cannot be applied to patients with contusions or other intracranial injuries, whose treatment and prognosis are different.".

Does Helsinki University Hospital treat subdural hematoma?

The Neurosurgical Department in Helsinki University Hospital has been an exception in its policy to also treat elderly patients with acute subdural hematomas surgically. Researchers from the University of Helsinki and Helsinki University Hospital have now determined how the patients' functional status before the injury and the use of oral anticoagulant medications influence the prognosis of patients 75 years or older operated on for an acute subdural hematoma.

Can falling cause brain hemorrhage?

In the worst case, falling may result in brain hemorrhage. Age is one of the most significant outcome predictors in patients with traumatic brain injury. If the patient is young, an acute subdural hematoma is normally treated through a neurosurgical operation.

Can elderly patients be treated surgically?

This is the first study to describe the results of surgically treated elderly patients with acute subdural hematomas. It is generally accepted that elderly patients who suffer from an acute subdural hematoma should not be treated surgically, as few survive and even fewer recover to an independent life .

What is a TBI?

Traumatic brain injury (TBI) is a form of nondegenerative acquired brain injury, resulting from an external physical force to the head (e.g., fall) or other mechanisms of displacement of the brain within the skull (e.g., blast injuries). Consistent with the diagnostic criteria detailed in the Diagnostic and Statistical Manual of Mental Disorders ...

How long does a TBI last?

Concussion/Mild TBI —loss of consciousness for up to 30 minutes; or confused or disoriented state lasting less than 24 hours; or memory loss lasting less than 24 hours. Excludes penetrating TBI. Results of a computed tomography (CT) scan, if obtained, are normal.

What are the levels of TBI?

The Department of Defense (DOD) defines the following levels of severity (Defense Health Agency, 2019): 1 Concussion/Mild TBI —loss of consciousness for up to 30 minutes; or confused or disoriented state lasting less than 24 hours; or memory loss lasting less than 24 hours. Excludes penetrating TBI. Results of a computed tomography (CT) scan, if obtained, are normal. 2 Moderate TBI —loss of consciousness for more than 30 minutes, but less than 24 hours; or confused or disoriented state lasting more than 24 hours; or memory loss lasting more than 24 hours but less than 7 days; or meets criteria for concussion/mild TBI but with an abnormal CT. Excludes penetrating TBI. A structural brain imaging study may be normal or abnormal. 3 Severe TBI —loss of consciousness for more than 24 hours; or confused or disoriented state lasting more than 24 hours; or memory loss lasting more than 7 days. Excludes penetrating TBI. A structural brain imaging study may be normal but usually is abnormal. 4 Penetrating TBI —open head injury; scalp, skull, and dura mater (outer layer of meninges) are penetrated. Caused by high-velocity projectiles, objects of lower velocity such as knives, or bone fragments from a skull fracture that are driven into the brain.

What is the second leading cause of TBI hospitalizations?

Falls and motor vehicle crashes were reported to be the first and second leading causes of all TBI-related hospitalizations (52% and 20%, respectively).

How many people have TBI?

According to the National Center for Injury Prevention and Control, an estimated cumulative 5.3 million individuals are living with a TBI-related disability in the United States. This represents a prevalence of approximately 2% of the U.S. population (CDC, 2015). Additional data suggest the prevalence of U.S. TBI-related disability after hospitalization to be 3.2 million (Zaloshnja, Miller, Langlois, & Selassie, 2008). Current studies estimate that approximately 775,000 older adults live with long-term disability associated with TBI (Zaloshnja et al., 2008).

What causes TBI?

Sports-related injuries and explosive blasts/military combat injuries are other leading causes of TBI. Acquiring a brain injury may predispose an individual to additional brain injuries before symptoms of the first have resolved completely; the second impact is more likely to cause brain swelling and widespread damage (Dessy, Rasouli, & Choudhri, 2015). See ASHA's resource on common classifications of TBI.

Is TBI a clinical or epidemiological study?

Incidence and prevalence rates of TBI vary across clinical and epidemiological studies. These variations are often due to differences in participant characteristics (e.g., ages included), diagnostic classification criteria within and across subtypes (e.g., mild TBI vs. severe TBI), and sources of data (e.g., hospital admissions, emergency room visits, general practitioner visits). Moreover, current statistics do not consider individuals who do not seek medical care. Therefore, these estimates may significantly underestimate the incidence and prevalence of TBI.

How to treat traumatic brain injury?

Treatment modalities vary extensively based on the severity of the injury and range from daily cognitive therapy sessions to radical surgery such as bilateral decompressive craniectomies. Guidelines have been set forth regarding the optimal management of TBI, but they must be taken in context of the situation and cannot be used in every individual circumstance. In this review article, we have summarized the current status of treatment for TBI in both clinical practice and basic research. We have put forth a brief overview of the various subtypes of traumatic injuries, optimal medical management, and both the noninvasive and invasive monitoring modalities, in addition to the surgical interventions necessary in particular instances. We have overviewed the main achievements in searching for therapeutic strategies of TBI in basic science. We have also discussed the future direction for developing TBI treatment from an experimental perspective.

How to minimize cerebral injury after TBI?

In order to minimize the cerebral injury after the TBI, therapeutic intervention is directed to prevent the first impact damage and to restrict the molecular and cellular cascade of the continuous cell damage. So far, there are no effective treatments for the first impact damage. Numerous studies have been carried out in an effort to search for treatment to prevent further neuronal damage after TBI and to enhance neural network reorganization and functional recovery. Unfortunately, these experimental studies have not been successfully translated into clinical therapies. Many questions have been raised through these years such as whether we fully understand the pathological dynamics after TBI and whether TBI models are clinically relevant.

How does TBI occur?

The primary deficit is related directly to the primary external impact of the brain. The secondary injury can happen from minutes to days from the primary impact and consists of a molecular, chemical, and inflammatory cascade responsible for further cerebral damage. This cascade involves depolarization of the neurons with the release of excitatory neurotransmitters such as glutamate and aspartate that lead to increased intracellular calcium. Intracellular calcium activates a series of mechanisms with the activation of enzymes caspases, calpases, and free radicals that results in degradation of cells either directly or indirectly through an apoptotic process. This degradation of neuronal cells is associated with an inflammatory response that further damages neuronal cells and incites a breach in the blood brain barrier (BBB) and further cerebral edema. This entire process is upregulated and downregulated as well through several mediators. After the second injury phase follows the recovery period, which consists of reorganization in an anatomical, molecular, and functional level.

How does raising the head of a traumatic brain injury affect ICP?

Raising the head of a traumatic brain-injured individual generally has rapid effects. ICP is reduced by displacement of CSF from the intracranial compartment as well as promotion of venous outflow. 5 Although the mean carotid pressure is reduced during head of bed elevation, ICP is reduced and cerebral blood flow (CBF) is unaffected. 17

What is second impact syndrome?

A very rare condition seen most often in athletes is second impact syndrome. The inciting event is often a concussion, however, the player may return to play prematurely and sustain a second concussive event amid continued recovery from their initial injury. The mechanism typically involves the rapid evolution of malignant cerebral edema, ensuing over a short-time course after the second injury takes place often on the playing field. The mortality rate ranges from 50% to 100%. 8

What is the intracranial volume?

The volume of the intracranial compartment is comprised of 3 separate contents: the brain parenchyma (83%), cerebrospinal fluid (CSF, 11%), and blood (6%). 4 Each of these contents relies on one another for a homeostatic environment within the skull. However, when intracranial volume exceeds that of its normal constituents, a cascade of compensatory mechanisms takes place. An increase in intracranial volume can take place in the traumatized brain via mass effect from blood, both cytotoxic and vasogenic edema, and venous congestion. Brain tissue is incompressible. As a result, edematous brain tissue will initially cause an extrusion of CSF to the spinal compartment. Eventually, blood, especially that of venous origin, is also extruded away from the brain. Without proper intervention, and sometimes even with maximal intervention, the compensatory mechanisms fail and the end result is pathological brain compression and ensuing death. 5

Is oxidative stress a secondary effect of TBI?

It is thought that oxidative stress is a secondary effect of TBI. Therapeutic hypothermia has been shown in infants and children to decrease oxidative injury. 22 As the body’s temperature cools, the cerebral metabolic demand decreases. This type of therapy also comes with risks such as alterations in blood sugar, platelet count, and coagulation factors. Platelet count and coagulation factors must be checked before any invasive procedure when an individual is brought to a hypothermic state. Therapeutic cooling in the context of severe TBI has had mixed results and is currently a second-tier therapeutic modality. 23

What are the causes of trauma in older people?

Traumatic injury has many causes, including road traffic collisions, pedestrians being hit by vehicles, assault, domestic abuse and suicide attempts. However, the most frequent cause of injury in older people is falling, from either a low level (i.e. from standing or a chair), or a higher level (such as falling from a ladder).

How does medication affect healing?

Some older patients take a number of medicines and tablets on a daily basis such as aspirin, warfarin or painkillers, and these may affect the time it takes to heal after trauma. Warfarin, a blood thinning medicine, can cause internal and external bleeding after injuries.

Can ageing cause trauma?

Younger people also suffer these types of traumatic injuries, but ageing can mean that the effects of trauma may be more severe. In some older people the severity of injuries may be difficult to detect at first and recovery may be more complex and prolonged. This is due to a number of factors, such as:

Can a high level fall cause a traumatic injury?

However for some older people, both low and high level falls can result in significant traumatic injury.

Can you take warfarin after trauma?

Therefore it is recommended that older people who are prescribed warfarin should seek medical advice after trauma, even if the injury appears to be relatively simple . As a result of injury, older people may have to spend a considerable amount of time in hospital in comparison to their younger counterparts.

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