We identified characteristics among MDR TB patients associated with the following 3 dichotomous outcomes: drug resistance acquisition, expert consultation use, and death during TB treatment.
Is tuberculosis treatment outcome associated with outcome?
Treatment Outcome of TB and Factors Independently Associated with Outcome Logistic regression analysis was done for all characteristics. In the final multivariable logistic model, unsuccessful treatment outcome varied by weight, tuberculosis type, category of patients, and HIV status (Table 4 ).
What is the success rate of pulmonary tuberculosis (TB) treatment?
A value of less than 0.05 was considered as statistically significant in the final model. Results. Out of the 1584 pulmonary TB patients (882 males and 702 females) including all age group, 60.1% had successful outcome and 39.9% had unsuccessful outcome.
What are the real challenges for tuberculosis (TB) treatment?
Similarly in different parts of the world defaulted treatment, death, failure and transfer-out cases are the real challenges for TB treatment [ 12 T. Vasankari, P. Holmström, J. Ollgren, K. Liippo, M. Kokki, and P. Ruutu, “Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study,” BMC Public Health, vol. 7, article 291, 2007.
How many tuberculosis patients die before they complete treatment?
* Of 254 (137 DOT and 117 SAT) patients who completed therapy, were lost, failed or abandoned treatment, or died of tuberculosis, excluding 21 patients who died of other causes, died before completing at least 1 week of therapy, or transferred/moved before treatment completion.
What are treatment outcomes for tuberculosis?
Regarding the treatment outcome, 30.4% were cured, 62.1% completed their treatment, 3.9% died, 2.4% were defaulted, and the remaining 1.2% had failed treatment. The overall rate of the treatment success among the patients was 92.5%.
Which treatment outcomes are considered as treatment success for TB patient?
Of the total TB patients with known treatment outcome, the overall treatment success rate was 82.5%. Of these 65 (28%) were cured and 126 (54.3%) had completed their treatment. The treatment success rate of HIV-co-infected TB patients (n=40) included in TB treatment outcome analysis was 77.5%.
What is the treatment success rate for tuberculosis?
The WHO recommends that a good performing tuberculosis program should achieve at least 90% treatment success rate and 85% cure rate [2].
What are treatment outcomes?
5.1 Definition. Treatment outcome research was defined by Mowrer (1953) as a situation whereby the “emphasis is upon measuring significant aspects of personality before and after treatment and noting the nature and extent of the resulting changes” (p. 4).
What are the complications of TB?
Without treatment, tuberculosis can be fatal. Untreated active disease typically affects your lungs, but it can affect other parts of your body, as well....Tuberculosis complications include:Spinal pain. ... Joint damage. ... Swelling of the membranes that cover your brain (meningitis). ... Liver or kidney problems. ... Heart disorders.
What is the total duration of treatment of multidrug resistant tuberculosis?
Treatment of MDR-TB lasts for a long duration of approximately 2 years and consists of a combination of multiple second-line drugs, which are more expensive, less effective, and more toxic than the first-line drugs. Therefore, treatment outcomes for MDR-TB are poor, with a success rate of approximately 54% [2].
What is the outcome of tuberculosis?
Before the advent of antituberculous chemotherapy, the majority of patients with TB died within months or years after the development of disease. Approximately 70% of patients with untreated smear-positive TB were dead after 10 years [8]. Death was the only certain marker of the epidemiology and outcome of TB.
What is TB detection rate?
Globally, TB case detection rate has stagnated at around 60 % and has still not reached the 70 % target set for 2005 [6] with sub-Sahara Africa having a much lower rate of 52 % [3].
How can I improve my TB?
If you have an active TB disease you will probably be treated with a combination of antibacterial medications for a period of six to 12 months. The most common treatment for active TB is isoniazid INH in combination with three other drugs—rifampin, pyrazinamide and ethambutol.
What is a treatment outcome study?
research designed to evaluate the efficacy of interventions and to investigate the mechanism by which effective interventions produce change.
What is therapy outcome study?
research that investigates the end results of therapy or other interventions to which patients are exposed. The focus is primarily on the “cure” (or not) of patients, but the research also evaluates their experiences, preferences, and values, as well as the wider influence on society.
What is the purpose of a treatment outcome study?
Treatment outcome studies are designed to answer commonsense questions. To determine whether a treatment accomplishes anything, we have to know how patients who have not received the treatment fare. Perhaps untreated patients do just as well, implying that the treatment does not influence outcome at all.