- indication. first-line treatment given immediately after HIV exposure (such as in health care personnel) initiate within 72 hours.
- drug regimen. tenofovir, emtricitabine, and raltegravir. tenofovir, emtricitabine, and dolutegravir.
When should HIV treatment be started?
People with HIV should start taking HIV medicines as soon as possible after HIV is diagnosed. A main goal of HIV treatment is to reduce a person's viral load to an undetectable level. An undetectable viral load means that the level of HIV in the blood is too low to be detected by a viral load test.
At what stage of HIV infection is antiretroviral treatment recommended?
HIV treatment involves taking highly effective medicines called antiretroviral therapy (ART) that work to control the virus. ART is recommended for everyone with HIV, and people with HIV should start ART as soon as possible after diagnosis, even on that same day.
When do you start Haart therapy?
Currently, the standard of care for a treatment-naïve patient with HIV-1 is a three-drug, highly active antiretroviral therapy (HAART) regimen that is started as soon as possible after a patient tests positive for HIV.
When do you start antiretroviral CD4 count?
START (Strategic Timing of Antiretroviral Therapy) is a clinical trial enrolling patients with CD4 counts more than 500 cells/μL and randomizing them to either immediate therapy or deferral of therapy until the CD4 count is less than 350 cells/μL.
At what CD4 count should ART be initiated?
As a priority, ART should be initiated among all adults with severe or advanced HIV clinical disease (WHO clinical stage 3 or 4) and adults with CD4 count ≤350 cells/mm3 (strong recommendation, moderate-quality evidence).
When should I start taking zidovudine?
A 4-week zidovudine (ZDV) ARV prophylaxis regimen can be used in newborns whose mothers received ART during pregnancy and had viral suppression within 4 weeks prior to delivery (defined as a confirmed HIV RNA level <50 copies/mL) and for whom maternal adherence is not of concern (BII).
What is the most important factor to consider when deciding to initiate ARV therapy?
[17,18] Regardless of CD4 cell count, the decision to initiate ART should always include consideration of any co-morbid conditions, the willingness and readiness of the patient to initiate therapy, and the availability of resources.
When is the best time to start ART?
ART is recommended for all individuals with HIV to reduce the morbidity and mortality associated with HIV infection (AI) and to prevent HIV transmission to sexual partners and infants (AI). ART should be initiated as soon as possible after HIV diagnosis (AII).