TYMLOS is a prescription medicine used to: •decrease the chance of having a fracture of the spine and other bones in postmenopausal women with thinning and weakening bones (osteoporosis). •treat osteoporosis in postmenopausal women who are at high risk for bone fracture.
What is Tymlos used for?
Tymlos is a prescription medicine used to treat osteoporosis in postmenopausal women who have a high risk of bone fracture. It is not recommended that people use Tymlos for more than 2 years during their lifetime. Tymlos has caused bone cancer (osteosarcoma) in animals but it is not known whether this would occur in people using this medicine.
Who should take Tymlos for osteoporosis?
With osteoporosis, your bones may fracture or break more easily than usual. For this use, Tymlos is given to those with a high risk for bone fracture. (To learn more about risk factors for osteoporosis, see the “ Tymlos for osteoporosis ” section below.) Tymlos contains the active drug abaloparatide, which is a biologic medication.
What is the dosage for Tymlos?
However, be sure to use the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs. Tymlos comes as a solution inside a prefilled pen. Each pen holds enough of the drug to supply doses for 30 days. Tymlos is available in one strength: 2,000 mcg/milliliter (mL).
What type of Pharmacy can dispense Tymlos?
Your prescription will need to be sent to a specialty pharmacy that can dispense TYMLOS. What is a specialty pharmacy? Like your local pharmacy, specialty pharmacies prepare and dispense prescription medications. The difference is, specialty pharmacies are able to manage medications that local pharmacies may not.
What class is Tymlos?
Tymlos belongs to the class of drugs known as parathyroid hormone-related protein (PTHrP) analogs.
How is Tymlos dispensed?
TYMLOS injection is supplied as a sterile, colorless, clear solution in a glass cartridge which is pre-assembled into a disposable single-patient-use pen. The pen is intended to deliver 30 once daily abaloparatide doses of 80 mcg in 40 mcL.
What treatment follows Tymlos?
Patients are supposed to follow up Tymlos treatment by using bisphosphonates for several years to maintain bone density gains. Radius Health will boast that their Tymlos drug reduces the relative risk of new vertebral fractures by 86% and also lessens the chance of nonvertebral fractures by 43% .
Is Tymlos a specialty drug?
Your prescription will need to be sent to a specialty pharmacy that can dispense TYMLOS.
Is TYMLOS covered by Medicare?
Do Medicare prescription drug plans cover Tymlos? Yes. 71% of Medicare prescription drug plans cover this drug.
Which is better Prolia or TYMLOS?
Prolia has an average rating of 2.7 out of 10 from a total of 322 ratings on Drugs.com. 14% of reviewers reported a positive effect, while 79% reported a negative effect. Tymlos has an average rating of 4.3 out of 10 from a total of 73 ratings on Drugs.com.
What is the newest osteoporosis treatment?
Romosozumab (Evenity). This is the newest bone-building medication to treat osteoporosis. It is given as an injection every month at your doctor's office and is limited to one year of treatment.
What is the safest injection for osteoporosis?
Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors. It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown. It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth.
When was Tymlos approved by the FDA?
Approval Date: 04/28/2017.
What is the retail price of Tymlos?
The average cost of Tymlos is around $3,403.79 for 1, 1.56ML of 3120MCG/1.56ML Solution Pen-injector. To save on the cost of Tymlos, you could use a SingleCare Tymlos coupon.
Is Tymlos safer than Forteo?
Tymlos is marketed as a better version of Forteo, boasting that it reduces the relative risk of nonvertebral fractures by 43%. But, relative risk can be a deceivingly inflated statistic. In actuality, for both drugs there was just a 2-4% reduction in absolute risk of non vertebral fractures.
Is Tymlos available us?
No. There is currently no therapeutically equivalent version of Tymlos available in the United States.
How to get the most out of Tymlos?
Here are some tips to help you stay on track: Take TYMLOS at the same time each day. For example, with breakfast or at bedtime. Set an alert on your phone to remind you. Keep your doctor’s office informed of your progress.
Can you take Tymlos with food?
TYMLOS is a daily injection that you can take with or without food . The helpful video below shows you how to prep, use and store your TYMLOS pen. To jump to a specific section of the video, click on the chapter titles of the video.
Can you use Tymlos pen for first time?
Before you use TYMLOS for the first time, a healthcare provider should show you how to prepare and inject TYMLOS. Do not try to use the TYMLOS pen until you have been shown the right way to inject.
What is Tymlos used for?
TYMLOS is a prescription medicine used to: decrease the chance of having a fracture of the spine and other bones in postmenopausal women with thinning and weakening bones (osteoporosis). treat osteoporosis in postmenopausal women who are at high risk for bone fracture.
How long can you use Tymlos?
It is not recommended that people use TYMLOS for more than 2 years during their lifetime.
How many mcg is in a TYMLOS pen?
Injection: 3120 mcg/1.56 mL (2000 mcg/mL) in a single-patient-use prefilled pen. The prefilled pen delivers 30 doses of TYMLOS, each containing 80 m cg of abaloparatide in 40 mcL of a sterile, clear, colorless solution.
Where to administer Tymlos?
Administer TYMLOS as a subcutaneous injection into the periumbilical region of the abdomen. Rotate the site of the injection every day and administer at approximately the same time every day. Do not administer intravenously or intramuscularly.
Can Tymlos cause hypercalcemia?
TYMLOS may cause hypercalcemia. TYMLOS is not recommended in patients with preexisting hypercalcemia or in patients who have an underlying hypercalcemic disorder, such as primary hyperparathyroidism, because of the possibility of exacerbating hypercalcemia [see ADVERSE REACTIONS ].
Does Tymlos cause calcium?
In the clinical trial of women with postmenopausal osteoporosis, TYMLOS caused increases in serum calcium concentrations [see WARNINGS AND PRECAUTIONS ]. The incidence of hypercalcemia, defined as albumin -corrected serum calcium ≥10.7 mg/dL at 4 hours following injection at any visit was 3% in TYMLOS-treated patients and 0.1% with placebo. Pre-dose serum calcium was similar to baseline in both groups. There were 2 (0.2%) TYMLOS-treated patients and no placebo-treated patients who discontinued from the study due to hypercalcemia. The incidence of hypercalcemia with TYMLOS was higher in patients with mild or moderate renal impairment (4%) compared to patients with normal renal function (1%).
Can TYMLOS cause kidney stones?
TYMLOS can cause some people to have higher levels of calcium in their urine than normal. Increased calcium may also cause you to develop kidney stones ( urolithiasis) in your kidneys, bladder or urinary tract.
How long can you use tymlos?
Tymlos should not be used for longer than two years.
What is Tymlos a brand?
Tymlos is a brand (trade) name for abaloparatide. Abaloparatide is a man-made version of a protein related to the human parathyroid hormone (also called parathyrin). Parathyrin is important in bone remodeling where bone tissue is resorbed and rebuilt over time.
How long can you keep Tymlos in the refrigerator?
Keep unopened Tymlos in the refrigerator at 2°C to 8°C (36°F to 46°F). May be stored for up to 30 days at room temperature. Each pre-filled pen contains enough Tymlos for 30 separate injections. Only use the injection pen provided with Tymlos; do not transfer to another container.
Can you take Tymlos if you forgot your daily dose?
Follow his/her advice and talk to him/her before taking any other supplements or medication. If you forget your daily dose of Tymlos, just continue with your normal dosing schedule.
Why do people use tymlos?
They may fracture or break more easily than usual. For this use, Tymlos is given to females with a high risk of bone fracture. (To learn more about risk factors for osteoporosis, see the “ Tymlos for osteoporosis ” section below.)
How often can you give Tymlos?
The drug is typically given once each day as a subcutaneous injection (an injection under your skin). Your doctor or healthcare provider will show you how to give yourself injections of the drug. Tymlos is available in one strength: 2,000 micrograms/milliliter (mcg/mL). One pen is meant to last 1 month.
What is the difference between Forteo and Tymlos?
Tymlos contains the active drug abaloparatide, while Forteo contains the active drug teriparatide. Tymlos is a form of the natural human parathyroid hormone that your body produces naturally. Forteo is a form of parathyroid hormone that’s created in a lab.
How many mcg of Tymlos should I take a day?
The Tymlos dosage your doctor will prescribe is typically 80 micrograms (mcg) per day. This is one injection. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.
How far away from the belly button should you give Tymlos?
Tymlos should be injected into the belly, at least 2 inches away from the belly button. Your doctor or a healthcare provider will show you how to yourself give injections of the drug.
Where to inject Forteo and Tymlos?
Tymlos should be injected into the belly, at least 2 inches away from the belly button. Forteo should be injected into the thigh or belly.
What is a biosimilar drug?
A biosimilar medication is a drug that’s similar to a brand-name biologic drug (the parent drug). Biosimilar drugs are still safe medications and still work in the same way as the original biologic. Like generic forms, biosimilar drugs often cost less than brand-name drugs.
How It Works
- Tymlos is a brand (trade) name for abaloparatide which may be used to increase bone density.
- Tymlos (abaloparatide) is a man-made version of a protein related to the human parathyroid hormone (also called parathyrin). Parathyrin is important in bone remodeling where bone tissue is resorbed...
- Tymlos belongs to the class of drugs known as parathyroid hormone-related protein (PTHrP…
- Tymlos is a brand (trade) name for abaloparatide which may be used to increase bone density.
- Tymlos (abaloparatide) is a man-made version of a protein related to the human parathyroid hormone (also called parathyrin). Parathyrin is important in bone remodeling where bone tissue is resorbed...
- Tymlos belongs to the class of drugs known as parathyroid hormone-related protein (PTHrP) analogs.
Upsides
- May be considered for the treatment of osteoporosis in postmenopausal women who have tried and not responded to, or been intolerant of, other medications for osteoporosis.
- Significantly reduces the risk of vertebral and nonvertebral fractures.
- No dosage adjustment is required in kidney disease. The manufacturer does not state if a dosage adjustment is needed in liver disease.
- May be considered for the treatment of osteoporosis in postmenopausal women who have tried and not responded to, or been intolerant of, other medications for osteoporosis.
- Significantly reduces the risk of vertebral and nonvertebral fractures.
- No dosage adjustment is required in kidney disease. The manufacturer does not state if a dosage adjustment is needed in liver disease.
- There are no significant drug interactions reported with Tymlos.
Downsides
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. High calcium levels in urine (may exacerbate active or recent urolithiasis), increased uric acid levels, and redness or pain around the injection site are the most common side effects reported. Dizziness, headache, naus…
Bottom Line
- Tymlos is an injection that is given daily under the skin to treat osteoporosis in postmenopausal women who have been intolerant of other medications or those medications have been ineffective. Tymlos should not be used for longer than two years.
Tips
- Inject Tymlos under the skin as instructed into the area around your belly button (periumbilical region). Rotate the injection site every day and administer it at the same time every day. Do not ad...
- Keep unopened Tymlos in the refrigerator at 2°C to 8°C (36°F to 46°F). May be stored for up to 30 days at room temperature. Each pre-filled pen contains enough Tymlos for 30 separate inj…
- Inject Tymlos under the skin as instructed into the area around your belly button (periumbilical region). Rotate the injection site every day and administer it at the same time every day. Do not ad...
- Keep unopened Tymlos in the refrigerator at 2°C to 8°C (36°F to 46°F). May be stored for up to 30 days at room temperature. Each pre-filled pen contains enough Tymlos for 30 separate injections. On...
- Your doctor may require you to take supplements or change aspects of your diet while you are taking Tymlos. Follow his/her advice and talk to him/her before taking any other supplements or medication.
- If you forget your daily dose of Tymlos, just continue with your normal dosing schedule. Do n…
Response and Effectiveness
- Tymlos reaches peak blood levels in approximately 30 minutes.
- The cumulative lifetime duration of use of Tymlos and other parathyroid hormone analogs should not exceed two years.
Interactions
- Few interaction studies have been done with Tymlos. Medicines that interact with Tymlos may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Tymlos. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your do…
Further Information
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Tymlos only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright 1996-2022 Drugs.com. Revision date: February 15, 2022. Medical Disc…